Brendan Cormack

Image of Dr. Brendan Cormack

Brendan Cormack

Professor
Primary Appointment: 
Molecular Biology and Genetics
410-614-4923

725 N. Wolfe Street
617 Hunterian
Baltimore MD 21205

Research topic: 

Fungal pathogenesis: the host-pathogen interaction for the yeast pathogen Candida glabrata

Selected Publications: 

Kaur R, Ma B, Cormack BP. A family of glycosylphosphatidylinositol-linked asparyl proteases is required for virulence of Candida glabrata. Proceedings of the National Academy of Sciences 2007; 104:7628-7633.

Domergue  R., Castaсo I, De Las Peсas A,  Zupancic M,  Lockatell V, Hebel JR, Johnson D and Cormack BP (2005) Nicotinic acid limitation regulates silencing of Candida adhesins during UTI. Science. 308: 866-870.

Castaсo, I., Pan S, Zupancic M, Hennequin C, Dujon B, and Cormack BP (2005) Telomere length control and transcriptional regulation of sub-telomeric adhesins in Candida glabrata. Mol Microbiol. 55: 1246-1258.

Frieman, MB and  Cormack BP (2003) The omega-site sequence of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae can determine distribution between the membrane and the cell wall. Mol Microbiol. 50: 883-896.

De Las Peсas A, Pan S, Castaсo I, Alder J, Cregg R and Cormack BP (2003) Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1- and SIR-dependent transcriptional silencing. Genes Dev. 17(18): 2245-2258.

Castaсo I,  Kaur R, Pan S,  Cregg R, De Las Peсas A, Guo N, Biery M,  Craig N annd Cormack BP (2003) Tn7-Based Genome-Wide Random Insertional Mutagenesis of Candida glabrata. Genome Res. 13(5): 905-913.

Frieman, MB, McCaffery JM and Cormack BP  (2002) Modular domain structure in the Candida glabrata adhesin Epa1p, a beta1,6 glucan-cross-linked cell wall protein. Mol Microbiol. 46(2): 479-492.