Siew Cheng Phua

Image of Siew Cheng Phua

Siew Cheng Phua

BS, Nanyang Technological University
Alumni
Associated BCMB Faculty Member: 
Selected Publications:
Phua, SC., Nihongaki, Y. and Inoue, T., 2018, “Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides,” Curr Opin Cell Biol.; 50:72-78. PMCID: PMC5911401 PubMed
Phua, SC., Chiba, S., Suzuki, M., Su, E., Roberson, EC., Pusapati, GV., Setou, M., Rohatgi, R., Reiter, JF., Ikegami, K. and Inoue, T., 2017, "Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision," Cell. 168(1-2):264-279.e15. PMCID: PMC5660509 PubMed
Garcia-Gonzalo FR*, Phua SC*, Roberson EC, Garcia III G, Abedin M, Schurmans S, Inoue T, Reiter JF. 2015. Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Developmental Cell. 34: 400-409. (*co-first authors) PMCID: PMC4557815 PubMed  
Phua, SC., Lin, YC. and Inoue, T., 2015, "An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli," Cell Calcium, 58: 415-422, Review. PMCID: PMC4564334 [Available on 2016-10-01] PubMed  
Phua, SC., Lin, YC. and Inoue, T., 2015, "An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli," Cell Calcium. 58(4):415-22. Review. PMID: 25828566 PubMed​
Lin, YC., Niewiadomski, P., Lin, B., Nakamura, H., Phua, SC., Jiao, J., Levchenko, A., Inoue, T., Rohatgi, R. and Inoue, T., 2013, "Chemically inducible diffusion trap at cilia reveals molecular sieve-like barrier," Nat Chem Biol. 9(7):437-43. PMCID: PMC3870470 PubMed  
Lin, YC., Phua, SC., Lin, B. and Inoue, T.,  2013, "Visualizing molecular diffusion through passive permeability barriers in cells: conventional and novel approaches," Curr Opin Chem Biol. 17(4):663-71. Review. PMCID: PMC3860267 PubMed  
Su, S., Phua, SC., DeRos,e R., Chiba, S., Narita, K., Kalugin, PN., Katada, T., Kontani, K., Takeda, S. and Inoue, T., 2013, "Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia," Nat Methods. 10(11):1105-7. PMCID: PMC3860264 PubMed  
Phua, SC., Pohlmeyer, C. and Inoue, T., 2012, "Rapidly relocating molecules between organelles to manipulate small GTPase activity," ACS Chem Biol. 7(12):1950-5. PMCID: PMC3528809 PubMed
Beginning year: 
2011
Graduation year: 
2017
Position: 
Postdoctoral fellow
Affiliation: 
Institute of Molecular and Cellular Biology (A*STAR Singapore)
Affiliation type: 
Academic/Research Institution
Position type: 
Postdoctoral Fellow