Recent Publications


Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. 2019 Dec. “Massive centriole production can occur in the absence of deuterosomes in multiciliated cells.” Nat Cell Biol.;21(12):1544-1552. doi: 10.1038/s41556-019-0427-x. PMID: 31792378. PMCID: PMC6913274. PubMed.  
Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, Wong GW, Hankenson KD. 2019 Dec 6. “CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing.” J Orthop Res..doi:10.1002/jor.24553. [Epub ahead of print]. PMID: 31808575. PubMed.  
Park EM, Scott PM, Clutario K, Cassidy KB, Zhan K, Gerber SA, Holland AJ. 2020 Jan 6. “WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication.” J Cell Biol.;219(1). pii: e201904203. doi: 10.1083/jcb.201904203. PMID: 31874114. PubMed.  


Rodriguez S, Stewart AN, Lei X, Cao X, Little HC, Fong V, Sarver DC, Wong GW. 2019 Nov 5. “PRADC1: a novel metabolic-responsive secretory protein that modulates physical activity and adiposity.” FASEB J.:fj201901279R. doi: 10.1096/fj.201901279R. PMID: 31689374. PubMed.  
Lee JH, Berger JM. 2019 Oct 30. “Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II.” Genes (Basel).;10(11). pii: E859. doi: 10.3390/genes10110859. Review. PMID: 31671531. PubMed.  
Georgess D, Padmanaban V, Sirka OK, Coutinho K, Choi A, Frid G, Neumann NM, Inoue T, Ewald AJ.  2019 Nov 1 “Twist1-induced epithelial dissemination requires Prkd1 signaling.” Cancer Res. pii: canres.3241.2018. doi: 10.1158/0008-5472.CAN-18-3241. PMID: 31676574. PubMed.  
Le TT, Gao X, Park SH, Lee J, Inman JT, Lee JH, Killian JL, Badman RP, Berger JM, Wang MD. 2019 Oct 17. “Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity.” Cell.;179(3):619-631.e15. doi: 10.1016/j.cell.2019.09.034. PMID: 31626768. PubMed  
Allen J, Hao S, Sears CL, Timp W. 2019 May 21. “Epigenetic Changes Induced by Bacteroides fragilis Toxin” Infect Immun.;87(6). pii: e00447-18. doi: 10.1128/IAI.00447-18. Print 2019 Jun. PMID: 30885929. PMCID: PMC6529667. PubMed.  
Keener R, Connelly CJ, Greider CW. 2019 Oct 23. “Tel1 Activation by the MRX Complex Is Sufficient for Telomere Length Regulation but Not for the DNA Damage Response in Saccharomyces cerevisiae. Genetics. pii: genetics.302713.2019. doi: 10.1534/genetics.119.302713. [Epub ahead of print] PMID: 31645360. PubMed  
Bowman CE, Selen Alpergin ES, Cavagnini K, Smith DM, Scafidi S, Wolfgang MJ. 2019 Oct 29. “Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress.” Cell Rep.;29(5):1299-1310.e3. doi: 10.1016/j.celrep.2019.09.053. PMID: 31665641. PubMed.  
Comert F, Greenwood A, Maramba J, Acevedo R, Lucas L, Kulasinghe T, Cairns LS, Wen Y, Fu R, Hammer J, Blazyk J, Sukharev S, Cotten ML, Mihailescu M. 2019 Oct 16.“The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels” J Biol Chem. pii: jbc.RA119.010232. doi: 10.1074/jbc.RA119.010232. [Epub ahead of print] PMID: 31619519. PubMed
Kothari P, Johnson C, Sandone C, Iglesias PA, Robinson DN. 2019 Sep 2. “How the mechanobiome drives cell behavior, viewed through the lens of control theory.” J Cell Sci. 132(17). pii: jcs234476. doi: 10.1242/jcs.234476. Review. PMID: 31477578. PubMed.  
Frandolig JE, Matney CJ, Lee K, Kim J, Chevée M, Kim SJ, Bickert AA, Brown SP. 2019 Sep 17. “The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina.” Cell Rep. 28(12):3131-3143.e5. doi: 10.1016/j.celrep.2019.08.048. PMID: 31533036. PubMed.  
Padmanaban V, Krol I, Suhail Y, Szczerba BM, Aceto N, Bader JS, Ewald AJ. 2019 Sep. “E-cadherin is required for metastasis in multiple models of breast cancer.” Nature. 573(7774):439-444. doi: 10.1038/s41586-019-1526-3. Epub 2019 Sep 4. PMID: 31485072. PubMed.  
Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, Gordon M, Meirman R, Millan-Zambrano G, Ayestaran I, Salguero I, Sharan R, Li R, Kupiec M, Jackson SP. 2019 Sep. “Genome architecture and stability in the Saccharomyces cerevisiae knockout collection.” Nature. 573(7774):416-420. doi: 10.1038/s41586-019-1549-9. Epub 2019 Sep 11. PMID: 31511699. PubMed.  
Tan Y, Cahan P. 2019 Aug 28. “SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species.” Cell Syst.;9(2):207-213.e2. doi: 10.1016/j.cels.2019.06.004. Epub 2019 Jul 31. PMID: 31377170. PMCID: PMC6715530.  PubMed  
Vissers C, Kageyama R. 2019 Aug 19. “Bursting the Notch Bubble: New Insights into In Vivo Transcriptional Dynamics.” Dev Cell.;50(4):393-394. doi: 10.1016/j.devcel.2019.07.028. PMID: 31430449. PubMed.  
Pike AM, Strong MA, Ouyang JPT, Greider CW. 2019 Aug 5. “TIN2 functions with TPP1/POT1 to stimulate telomerase processivity.” Mol Cell Biol.. pii: MCB.00593-18. doi: 10.1128/MCB.00593-18. PMID: 31383750. PubMed  
Wang Z, Hutcherson SM, Yang C, Jattani RP, Tritapoe JM, Yang YK, Pomerantz JL. J Biol Chem. 2019 Aug 7. “Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling.” pii: jbc.RA119.009551. doi: 10.1074/jbc.RA119.009551. PMID: 31391255. PubMed  
Ouyang JPT, Folkmann A, Bernard L, Lee CY, Seroussi U, Charlesworth AG, Claycomb JM, Seydoux G. 2019 Aug 6. “P Granules Protect RNA Interference Genes from Silencing by piRNAs.” Dev Cell.. pii: S1534-5807(19)30632-X. doi: 10.1016/j.devcel.2019.07.026. PMID: 31402283. PubMed.  
Pundir P, Liu R, Vasavda C, Serhan N, Limjunyawong N, Yee R, Zhan Y, Dong X, Wu X, Zhang Y, Snyder SH, Gaudenzio N, Vidal JE, Dong X. 2019 Jul 10. “A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity.” Cell Host Microbe.;26(1):114-122.e8. doi: 10.1016/j.chom.2019.06.003. Epub 2019 Jul 2. PMID: 31278040. PMCID: PMC6649664. PubMed.  
Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, Snyder SH. 2019 Jul 23. “Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.” Cell Chem Biol. pii: S2451-9456(19)30218-1. doi: 10.1016/j.chembiol.2019.07.006. [Epub ahead of print] PMID: 31353321. PubMed.  
Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF. 2019 Jul 10. “The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.” Cell Host Microbe.;26(1):73-85.e4. doi: 10.1016/j.chom.2019.06.005. PMID: 31295427. PMCID: PMC6724192 PubMed.  
Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC. 2019 Jul 23. “FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.” Cell Rep.;28(4):845-854.e5. doi: 10.1016/j.celrep.2019.06.072. PMID: 31340148. PubMed.  
Hayward D, Kouznetsova VL, Pierson HE, Hasan NM, Guzman ER, Tsigelny IF, Lutsenko S. 2019 Jul 23. “ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.” J Biol Chem.. pii: jbc.RA119.008231. doi: 10.1074/jbc.RA119.008231. [Epub ahead of print]. PMID: 31337707. PubMed.  
Surcel A, Schiffhauer ES, Thomas DG, Zhu Q, DiNapoli KT, Herbig M, Otto O, West-Foyle H, Jacobi A, Kräter M, Plak K, Guck J, Jaffee EM, Iglesias PA, Anders RA, Robinson DN. 2019 Jul 29. “Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14.” Cancer Res.. pii: canres.3131.2018. doi: 10.1158/0008-5472.CAN-18-3131. [Epub ahead of print] PMID: 31358530. PubMed.  
Johnson DM, Andrew DJ. 2019 Jun 26. “Role of tbc1 in Drosophila embryonic salivary glands.” BMC Mol Cell Biol. 20(1):19. doi: 10.1186/s12860-019-0198-z. PMID: 31242864. PubMed.  
Allen J, Sears CL. 2019 Feb 25. “Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development.” Genome Med. 20(1):19. doi: 10.1186/s12860-019-0198-z. PMID: 30803449. PMCID: PMC6388476. PubMed  
Zhu L, Liao SE, Fukunaga R. 2019 Jun 23. “Drosophila Regnase-1 RNase is required for mRNA and miRNA profile remodelling during larva-to-adult metamorphosis.” RNA Biol. 1-15. doi: 10.1080/15476286.2019.1630799. [Epub ahead of print]. PMID: 31195914. PubMed  
Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF. 2019 Jun 13. “SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL.” J Cell Biol. pii: jcb.201803041. doi: 10.1083/jcb.201803041. [Epub ahead of print]. PMID: 31197030. PubMed.  
D'Orazio KN, Wu CC, Sinha N, Loll-Krippleber R, Brown GW, Green R. 2019 Jun 20. “The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay.” Elife. 8. pii: e49117. doi: 10.7554/eLife.49117. PMID: 31219035. PubMed.  
Zieman AG, Poll BG, Ma J, Coulombe PA. 2019 Jul 1. “Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.” Hum Mol Genet. 28(13):2255-2270. doi: 10.1093/hmg/ddz050. PMID: 31220272. PubMed  
Dresselhaus EC, Meffert MK., 2019 May 9. "Cellular Specificity of NF-κB Function in the Nervous System." Front Immunol, 10:1043. doi: 10.3389/fimmu.2019.01043. eCollection 2019. Review. PMCID: PMC6520659. PubMed.
Weaver J, Mohammad F, Buskirk AR, Storz G, 2019 Mar 5. "Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes." MBio, 10(2). pii: e02819-18. doi: 10.1128/mBio.02819-18. PMCID: PMC6401488. PubMed.
Meixiong J, Vasavda C, Snyder SH, Dong X., 2019 May 21. "MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus." Proc Natl Acad Sci USA, 116(21):10525-10530. doi: 10.1073/pnas.1903316116. PubMed.
DeFelice MM*, Clark HR*, Hughey JJ*, Maayan I, Kudo T, Gutschow MV, Covert MW, Regot S., 2019 Apr 30. "NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop." Sci Signal. 12(579). pii: eaau3568. doi: 10.1126/scisignal.aau3568. *equal contribution. PubMed.
Moyer TC, Holland AJ., 2019 May 22. "PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall." Elife, 8. pii: e46054. doi: 10.7554/eLife.46054. [Epub ahead of print]. PubMed.
Zhu L, Liao SE, Ai Y, Fukunaga R, 2019 May 30. "RNA methyltransferase BCDIN3D is crucial for female fertility and miRNA and mRNA profiles in Drosophila ovaries.", PLoS One.14(5):e0217603. doi: 10.1371/journal.pone.0217603. eCollection 2019. PubMed.
Syu GD, Wang SC, Ma G, Liu S, Pearce D, Prakash A, Henson B, Weng LC, Ghosh D, Ramos P, Eichinger D, Pino I, Dong X, Xiao J, Wang S, Tao N, Kim KS, Desai PJ, Zhu H., 2019 Apr 30, "Development and application of a high-content virion display human GPCR array." Nat Commun.;10(1):1997. doi: 10.1038/s41467-019-09938-9. PMCID: PMC6491619  PubMed.
Bowman CE, Scafidi J, Scafidi S., 2019, ”Metabolic perturbations after pediatric TBI: It's not just about glucose”, Exp Neurol. Review. 316:74-84. PubMed  
Clister T, Greenwald EC, Baillie GS, Zhang J., 2019, “AKAP95 Organizes a Nuclear Microdomain to Control Local cAMP for Regulating Nuclear PKA”, Cell Chem Biol. pii: S2451-9456(19)30080-7. PubMed  
Bowman CE, Selen Alpergin ES, Ellis JM, Wolfgang MJ., 2019, “Loss of ACOT7 potentiates seizures and metabolic dysfunction”, Am J Physiol Endocrinol Metab. doi: 10.1152/ajpendo.00537.2018. PubMed  
Liao SE, Kandasamy SK, Zhu L, Fukunaga R. 2019 Jul.”DEAD-box RNA helicase Belle posttranscriptionally promotes gene expression in an ATPase activity-dependent manner.” RNA.;25(7):825-839. doi: 10.1261/rna.070268.118. Epub 2019 Apr 12. PMID: 30979781. PMCID: PMC6573787. PubMed.  
Little HC, Rodriguez S, Lei X, Tan SY, Stewart AN, Sahagun A, Sarver DC, Wong GW., 2019, “Myonectin deletion promotes adipose fat storage and reduces liver steatosis” FASEB J. fj201900520R. PubMed  
Lariviere PJ, Mahone CR, Santiago-Collazo G, Howell M, Daitch AK, Zeinert R, Chien P, Brown PJB, Goley ED., 2019, “An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation”, Curr Biol. pii: S0960-9822(19)30394-X. PubMed  
Patel SP, Vasavda C, Ho B, Meixiong J, Dong X, Kwatra SG., 2019, “Cholestatic pruritus: Emerging mechanisms and therapeutics”, J Am Acad Dermatol. pii: S0190-9622(19)30627-9. Review. PubMed  
Cook EK, Sell GL, Schaffer TB, Margolis SS., 2019, "The emergence of Ephexin5 as a therapeutic target in Alzheimer's disease." Expert Opin Ther Targets. 23(4):263-265. PubMed
Calzada, E.,Avery E, Sam PN, Modak A, Wang C, McCaffery JM, Han X, Alder NN, Claypool SM., 2019, "Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc1 complex function." Nat Commun. 10(1):1432 PMCID: PMC6441012 PubMed
Putnam A, Cassani M, Smith J, Seydoux G. 2019, "A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos," Nat Struct Mol Biol. (3):220-226. doi: 10.1038/s41594-019-0193-2. Epub 2019 Mar 4. PMID: 30833787. PMCID: PMC6668929  PubMed  
Latallo MJ, Livingston NM, Wu B., 2019, "Translation imaging of single mRNAs in Established Cell Lines and Primary Cultured Neurons." Methods. pii: S1046-2023(18)30341-4. Review. PubMed