Recent Publications


Cieniewicz, AM.*, Moreland, L., Ringel, AE., Mackintosh, SG., Raman, A*., Gilbert, TM.*, Wolberger, C., Tackett, AJ. and Taverna, SD., 2014, "The bromodomain of Gcn5 regulates site-specificity of lysine acetylation on histone H3," Mol Cell Proteomics,13(11):2896-910.  PMCID: PMC4223480 *equal contribution​ PubMed
Gilbert, TM., McDaniel, SL., Byrum, SD., Cades, JA., Dancy, BC., Wade, H., Tackett, AJ., Strahl, BD. and Taverna, SD., 2014, "An H3K36me3 binding PWWP protein targets the NuA3 acetyltransferase complex to coordinate transcriptional elongation at coding regions," Mol Cell Proteomics, 13(11):2883-95. PMCID: PMC4223479​ PubMed
Li, Y.*, Ma, Q.*, Cherry, CM.* and Matunis, EL., 2014, "Steroid signaling promotes stem cell maintenance in the Drosophila testis," Dev Biol. 394(1):129-41.  PMCID: PMC4165524 *equal contribution​ PubMed
Kim, YJ., Lim, H., Li, Z., Oh, Y., Kovlyagina, I., Choi, IY., Dong, X. and Lee, G., 2014, "Generation of Multipotent Induced Neural Crest by Direct Reprogramming of Human Postnatal Fibroblasts with a Single Transcription Factor," Cell Stem Cell, 15(4):497-506 ​ PubMed
Debeljak, M., Freed, DN., Welch, JA., Haley, L., Beierl, K., Iglehart, BS., Pallavajjala, A., Gocke, CD., Leffell, MS., Lin, MT., Pevsner, J., Wheelan, SJ and Eshleman, JR., 2014, "Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection," J Mol Diagn. 16(5):495-503.      PubMed 
Colis, L., Ernst, G., Sanders, S., Liu, H., Sirajuddin, P., Peltonen, K., DePasquale, M., Barrow, JC. and Laiho, M., 2014, "Design, synthesis, and structure-activity relationships of pyridoquinazolinecarboxamides as RNA polymerase I inhibitors," J Med Chem 57(11):4950-61.​ PMCID: PMC4059246​ PubMed 
Prendergast, J., Umanah, GK., Yoo, SW., Lagerlöf, O., Motari, MG., Cole, RN., Huganir, RL., Dawson, TM., Dawson, VL. and Schnaar, RL., 2014, "Ganglioside regulation of AMPA receptor trafficking," J Neurosci. 34(39):13246-58. PMCID: PMC4172811  PubMed
Chung, S., Hanlon, CD. and Andrew, DJ., 2014, "Building and specializing epithelial tubular organs: the Drosophila salivary gland as a model system for revealing how epithelial organs are specified, form and specialize," Wiley Interdiscip Rev Dev Biol. 3(4):281-300. PMCID: PMC4448711 PubMed
Deng, K. and Siliciano, RF., 2014, "HIV: Early treatment may not be early enough," Nature.  PubMed
Fan, L., Guan, X., Wang, W., Zhao, JY., Zhang, H., Tiwari, V., Hoffman, PN., Li, M. and Tao, YX., 2014, "Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons," Mol Pain. 10(1):8.  PMCID: PMC3909300 ​ PubMed
Paix, A.*, Wang, Y.*, Smith, H., Lee, CY*., Calidas, D.*, Lu, T*., Smith, J.*, Schmidt, H.*, Krause, M. and Seydoux, G., 2014, "Scalable and Versatile Genome Editing Using Linear DNAs with Micro-homology to Cas9 Sites in Caenorhabditis elegans," Genetics, 198(4):1347-56.  PMCID: PMC4256755 *equal contribution​ PubMed
Li, Z., He, SQ., Xu, Q., Yang, F., Tiwari, V., Liu, Q., Tang, Z., Han, L., Chu, YX., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Guan, X., Wei, F., Raja, SN., Dong, X. and Guan, Y., 2014, "Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice," Pain, 155(8):1613-21. PMCID: PMC4104261  PubMed
Kim, YS.*, Chu, Y., Han, L*., Li, M., Li, Z.*, Lavinka, PC.*, Sun, S*., Tang, Z., Park, K.*, Caterina, MJ., Ren, K., Dubner, R., Wei, F. and Dong, X., 2014, "Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain," Neuron, 81(4):873-87.  PMCID: PMC3943838 *equal contribution PubMed
Gilbert, CE., Zuckerman, DM., Currier, PL. and Machamer, CE., 2014, "Three basic residues of intracellular loop 3 of the Beta-1 adrenergic receptor are required for golgin-160-dependent trafficking," Int J Mol Sci. 15(2):2929-45. PMCID: PMC3958891 PubMed
Brubaker, SW., Gauthier, AE., Mills, EW., Ingolia, NT. and Kagan, JC.,  2014, "A Bicistronic MAVS Transcript Highlights a Class of Truncated Variants in Antiviral Immunity," Cell. 2014 Feb 13;156(4):800-11. doi: 10.1016/j.cell.2014.01.021. PMCID: PMC3959641 PubMed
Meier, EL. and Goley, ED., 2014, "Form and function of the bacterial cytokinetic ring," Curr Opin Cell Biol. 26C:19-27.  PubMed
Oldach, L. and Zhang, J., 2014, "Genetically Encoded Fluorescent Biosensors for Live-Cell Visualization of Protein Phosphorylation," Chem Biol. 21(2):186-197. PMCID: PMC4050661  PubMed
Luperchio, TR., Wong, X. and Reddy, KL., 2014, "Genome regulation at the peripheral zone: lamina associated domains in development and disease," Curr Opin Genet Dev. 25C:50-61.  Review. PubMed
Huebner, RJ., Lechler, T. and Ewald, AJ., 2014, "Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells," Development. 141(5):1085-94. PMCID: PMC3929409 PubMed
Annaluru, N., Muller, H., Mitchell, LA., Ramalingam, S., Stracquadanio, G., Richardson, SM., Dymond, JS., Kuang, Z., Scheifele, LZ., Cooper, EM., Cai, Y., Zeller, K., Agmon, N., Han, JS., Hadjithomas, M., Tullman, J., Caravelli, K., Cirelli, K., Guo, Z., London, V., Yeluru, A., Murugan, S., Kandavelou, K., Agier, N., Fischer, G., Yang, K., Martin, JA., Bilgel, M., Bohutski, P., Boulier, KM., Capaldo, BJ., Chang, J., Charoen, K., Choi, WJ., Deng, P., DiCarlo, JE., Doong, J., Dunn, J., Feinberg, JI., Fernandez, C., Floria, CE., Gladowski, D., Hadidi, P., Ishizuka, I., Jabbari, J., Lau, CY., Lee, PA., Li, S., Lin, D., Linder, ME., Ling, J., Liu, J., Liu, J., London, M., Ma, H., Mao, J., McDade, JE., McMillan, A., Moore, AM., Oh, WC., Ouyang, Y., Patel, R., Paul, M., Paulsen, LC., Qiu, J., Rhee, A., Rubashkin, MG., Soh, IY., Sotuyo, NE., Srinivas, V., Suarez, A., Wong, A., Wong, R., Xie, WR., Xu, Y., Yu, AT., Koszul, R., Bader, JS., Boeke, JD. and Chandrasegaran, S., 2014, "Total synthesis of a functional designer eukaryotic chromosome," Science. 344(6179):55-8. . Erratum in: Science. 2014 May 23;344(6186):816. PMCID: PMC4033833 PubMed
Hodge, DL., Berthet, C., Coppola, V., Kastenmüller, W., Buschman, MD., Schaughency, PM., Shirota, H., Scarzello, AJ., Subleski, JJ., Anver, MR., Ortaldo, JR., Lin, F., Reynolds, DA., Sanford, ME., Kaldis, P., Tessarollo, L., Klinman, DM. and Young, HA., 2014, "IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice," J Autoimmun. 53:33-45. PMCID: PMC4148478 PubMed
Shamir, ER., Pappalardo, E., Jorgens, DM., Coutinho, K., Tsai, WT., Aziz, K., Auer, M., Tran, PT., Bader, JS. and Ewald, AJ., 2014, "Twist1-induced dissemination preserves epithelial identity and requires E-cadherin," J Cell Biol. 204(5):839-56. PMCID: PMC3941052 PubMed
Huebner, RJ. and Ewald, AJ., 2014, "Cellular foundations of mammary tubulogenesis," Semin Cell Dev Biol, 31:124-31. Review.​ PMCID: PMC4116098 PubMed
Sluch, VM. and Zack, DJ. 2014, "Stem cells, retinal ganglion cells and glaucoma," Dev Ophthalmol. 53:111-21. PMCID: PMC4547935  PubMed
Kim, MS., Pinto, SM., Getnet, D., Nirujogi, RS., Manda, SS., Chaerkady, R., Madugundu, AK., Kelkar, DS., Isserlin, R., Jain, S., Thomas, JK., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, NA., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, LD., Patil, AH., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, SK., Marimuthu, A., Sathe, GJ., Chavan, S., Datta, KK., Subbannayya, Y., Sahu, A., Yelamanchi, SD., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, KR., Syed, N., Goel, R., Khan, AA., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, TC., Zhong, J., Wu, X., Shaw, PG., Freed, D., Zahari, MS., Mukherjee, KK., Shankar, S., Mahadevan, A., Lam, H., Mitchell, CJ., Shankar, SK., Satishchandra, P., Schroeder, JT., Sirdeshmukh, R., Maitra, A., Leach, SD., Drake, CG., Halushka, MK., Prasad, TS., Hruban, RH., Kerr, CL., Bader, GD., Iacobuzio-Donahue, CA., Gowda, H. and Pandey, A., 2014, "A draft map of the human proteome, "Nature. 509(7502):575-81. PMCID: PMC4403737 PubMed
Chivukula, RR., Shi, G., Acharya, A., Mills, EW., Zeitels, LR., Anandam, JL., Abdelnaby, AA., Balch, GC., Mansour, JC., Yopp, AC., Maitra, A. and Mendell, JT., 2014, "An Essential Mesenchymal Function for miR-143/145 in Intestinal Epithelial Regeneration," Cell.157(5):1104-16. PMCID: PMC4175516​ PubMed
Salgado, M., Swanson, MD., Pohlmeyer, CW., Buckheit, RW 3rd., Wu, J., Archin, NM., Williams, TM., Margolis, DM., Siliciano, RF., Garcia, JV. and Blankson,  JN., 2014, "HLA-B*57 Elite Suppressor and Chronic Progressor HIV-1 Isolates Replicate Vigorously and Cause CD4+ T cell Depletion in Humanized BLT Mice," J Virol. 88:3340-3352  PMCID: PMC3957943 PubMed


Patenaude, C., Zhang, Y., Cormack, B., Koehler, J. and Rao, R., 2013, "Essential Role for Vacuolar Acidification in Candida albicans Virulence," J Biol Chem. 288(36):26256-64.  PMCID: PMC3764829PubMed
Frueh, DP., Goodrich, AC., Mishra, SH. and Nichols, SR., 2013, "NMR methods for structural studies of large monomeric and multimeric proteins," Curr Opin Struct Biol., 23, 734-9. PMCID: PMC3805735PubMed
Eyler, DE., Wehner, KA. and Green, R., 2013, "Eukaryotic release factor 3 is required for multiple turnovers of peptide release catalysis by eukaryotic release factor 1," J Biol Chem., 288(41):29530-8. PMCID: PMC3795251  PubMed
Yu, H., Lin, Z., Mattmann, ME., Zou, B., Terrenoire, C., Zhang, H., Wu, M., McManus, OB., Kass, RS., Lindsley, CW., Hopkins, CR. and Li, M., 2013, "Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels," Proc Natl Acad Sci U S A. 110(21):8732-7. PMCID: PMC3666726 PubMed
Shirley, MD, 2013, "Concerns regarding "Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA", Genomics. 102(4):430.  PubMed
Tu-Sekine, B., Goldschmidt, H., Petro, E. and Raben, DM., 2013, "Diacylglycerol kinase θ: regulation and stability," Adv Biol Regul. 53(1):118-26. PMCID: PMC3992713PubMed
Berk, JM., Maitra, S., Dawdy, AW., Shabanowitz, J., Hunt, DF. and Wilson, KL., 2013, "O-GlcNAc regulates emerin binding to BAF in a chromatin- and lamin B-enriched 'niche'," J Biol Chem. 288(42):30192-209. PMCID: PMC3798487  PubMed
Hu, S., Wan, J., Su, Y., Song, Q., Zeng, Y., Nguyen, HN., Shin, J., Cox, E., Rho, HS., Woodard, C., Xia, S., Liu, S., Lyu, H., Ming, GL., Wade, H., Song, H., Qian, J. and Zhu, H., 2013, "DNA methylation presents distinct binding sites for human transcription factors," Elife. 2:e00726. PMCID: PMC3762332 PubMed​
Zhang, YV., Raghuwanshi, RP., Shen, WL. and Montell, C., 2013, "Food experience-induced taste desensitization modulated by the Drosophila TRPL channel," Nat Neurosci. (10):1468-76. PMCID: PMC3785572  PubMed
Lessard, JC., 2013, "Molecular cloning," Methods Enzymol.529:85-98. PubMed  
Donnelly, CJ., Zhang, PW., Pham, JT., Heusler, AR., Mistry, NA., Vidensky, S., Daley, EL., Poth, EM., Hoover, B., Fines, DM., Maragakis, N., Tienari, PJ., Petrucelli, L., Traynor, BJ., Wang, J., Rigo, F., Bennett, CF., Blackshaw, S., Sattler, R. and Rothstein, JD., 2013, "RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention," Neuron. ;80(2):415-28. PMCID: PMC4098943 PubMed
Salgado, M., Buckheit, R., Gandhi, S., Berkenblit, G., Blankson, J., 2013, "Evolution of an Attenuated HIV-1 Isolate in an Elite Suppressor," AIDS Res Hum Retroviruses. PubMed
Lessard, JC., Piña-Paz, S., Rotty, JD., Hickerson, RP., Kaspar, RL., Balmain, A. and Coulombe, PA., 2013, "Keratin 16 regulates innate immunity in response to epidermal barrier breach," Proc Natl Acad Sci USA, 110(48):19537-42. PMCID: PMC3845144 PubMed
Lessard, JC., 2013, "Growth Media for E. coli," Methods Enzymol. 533:181-9. PMID: 24182923  PubMed
Abrams, EW., Cheng, YL. and Andrew, DJ., 2013, "Drosophila KDEL Receptor Function in the Embryonic Salivary Gland and Epidermis," PLoS One. 2013 Oct 18;8(10):e77618. PMCID: PMC3799842 PubMed
Teng, X., Dayhoff-Brannigan, M., Cheng, WC., Gilbert, CE., Sing, CN., Diny, N.L., Wheelan, SJ., Dunham, MJ., Boeke, JD., Pineda, FJ. and Hardwick, JM., 2013, "Genome-wide Consequences of Deleting Any Single Gene," Mol Cell. 52(4):485-94. PMCID: PMC3975072     PubMed
Dickey,. SW., Baker, RP., Cho, S. and Urban, S.., 2013, "Proteolysis inside the membrane is a rate-governed reaction not driven by substrate affinity," Cell. 2013 Dec 5;155(6):1270-81.  PMCID: PMC3917317 PubMed
He, SQ., Han, L., Li, Z., Xu, Q., Tiwari, V., Yang, F., Guan, X., Wang, Y., Raja, SN., Dong, X. and Guan, Y., 2013, "Temporal changes in MrgC expression after spinal nerve injur," Neuroscience. pii: S0306-4522(13)01065-8. PMCID: PMC3945476 PubMed
He, SQ., Li, Z., Chu, YX., Han, L., Xu, Q., Li, M., Yang, F., Liu, Q., Tang, Z., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Tiwari, V., Shechter, R., Wei, F., Raja, SN., Dong, X. and Guan, Y., 2013, "MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain," Pain, 155(3):534-44.  PMCID: PMC3945061 PubMed
Hua, ZL., Smallwood, PM. and Nathans, J., 2013, "Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons," Elife. 2:e01482.  PMCID: PMC3865743  PubMed
Pohlmeyer, CW., Buckheit, RW 3rd., Siliciano, RF. and Blankson, JN., 2013, "CD8+ T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants," Retrovirology. 10:152. PMCID: PMC3878989 PubMed
Zhou, Y. and Wang, X., 2013, "Spatially extended forward suppression in primate auditory cortex," Eur J Neurosci. PMID 24372934 PubMed
Berk, JM., Tifft, KE. and Wilson, KL., 2013, "The nuclear envelope LEM-domain protein emerin," Nucleus, 4(4):298-314. PMCID: PMC3810338  PubMed