Recent Publications

2013

Lessard, JC., 2013, "Molecular cloning," Methods Enzymol.529:85-98. PubMed  
Donnelly, CJ., Zhang, PW., Pham, JT., Heusler, AR., Mistry, NA., Vidensky, S., Daley, EL., Poth, EM., Hoover, B., Fines, DM., Maragakis, N., Tienari, PJ., Petrucelli, L., Traynor, BJ., Wang, J., Rigo, F., Bennett, CF., Blackshaw, S., Sattler, R. and Rothstein, JD., 2013, "RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention," Neuron. ;80(2):415-28. PMCID: PMC4098943 PubMed
Salgado, M., Buckheit, R., Gandhi, S., Berkenblit, G., Blankson, J., 2013, "Evolution of an Attenuated HIV-1 Isolate in an Elite Suppressor," AIDS Res Hum Retroviruses. PubMed
Lessard, JC., Piña-Paz, S., Rotty, JD., Hickerson, RP., Kaspar, RL., Balmain, A. and Coulombe, PA., 2013, "Keratin 16 regulates innate immunity in response to epidermal barrier breach," Proc Natl Acad Sci USA, 110(48):19537-42. PMCID: PMC3845144 PubMed
Lessard, JC., 2013, "Growth Media for E. coli," Methods Enzymol. 533:181-9. PMID: 24182923  PubMed
Abrams, EW., Cheng, YL. and Andrew, DJ., 2013, "Drosophila KDEL Receptor Function in the Embryonic Salivary Gland and Epidermis," PLoS One. 2013 Oct 18;8(10):e77618. PMCID: PMC3799842 PubMed
Teng, X., Dayhoff-Brannigan, M., Cheng, WC., Gilbert, CE., Sing, CN., Diny, N.L., Wheelan, SJ., Dunham, MJ., Boeke, JD., Pineda, FJ. and Hardwick, JM., 2013, "Genome-wide Consequences of Deleting Any Single Gene," Mol Cell. 52(4):485-94. PMCID: PMC3975072     PubMed
Dickey,. SW., Baker, RP., Cho, S. and Urban, S.., 2013, "Proteolysis inside the membrane is a rate-governed reaction not driven by substrate affinity," Cell. 2013 Dec 5;155(6):1270-81.  PMCID: PMC3917317 PubMed
He, SQ., Han, L., Li, Z., Xu, Q., Tiwari, V., Yang, F., Guan, X., Wang, Y., Raja, SN., Dong, X. and Guan, Y., 2013, "Temporal changes in MrgC expression after spinal nerve injur," Neuroscience. pii: S0306-4522(13)01065-8. PMCID: PMC3945476 PubMed
He, SQ., Li, Z., Chu, YX., Han, L., Xu, Q., Li, M., Yang, F., Liu, Q., Tang, Z., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Tiwari, V., Shechter, R., Wei, F., Raja, SN., Dong, X. and Guan, Y., 2013, "MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain," Pain, 155(3):534-44.  PMCID: PMC3945061 PubMed
Hua, ZL., Smallwood, PM. and Nathans, J., 2013, "Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons," Elife. 2:e01482.  PMCID: PMC3865743  PubMed
Pohlmeyer, CW., Buckheit, RW 3rd., Siliciano, RF. and Blankson, JN., 2013, "CD8+ T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants," Retrovirology. 10:152. PMCID: PMC3878989 PubMed
Zhou, Y. and Wang, X., 2013, "Spatially extended forward suppression in primate auditory cortex," Eur J Neurosci. PMID 24372934 PubMed
Berk, JM., Tifft, KE. and Wilson, KL., 2013, "The nuclear envelope LEM-domain protein emerin," Nucleus, 4(4):298-314. PMCID: PMC3810338  PubMed
Rath, P., Lal, B., Ajala, O., Li, Y., Xia, S., Kim, J. and Laterra, J., 2013, "In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells," Transl Oncol. 6(2):104-11. Epub 2013 Apr 1. PMCID: PMC3612837      PubMed
Ruch, TR. and Machamer, CE., 2012, "The coronavirus E protein: assembly and beyond," Viruses, 4(3):363-82. PMCID: PMC3347032 Pubmed 
Baile, MG. and Claypool, SM., 2013, "The power of yeast to model diseases of the powerhouse of the cell," Front Biosci (Landmark Ed). 18:241-78. Review, PMCID: PMC3874933 PubMed
Zhang, F., Bhat, S., Gabelli, SB., Chen, X., Miller, MS., Nacev, BA., Cheng, YL., Meyers, DJ., Tenney, K., Shim, JS., Crews, P., Amzel, LM., Ma, D. and Liu, JO., 2013, "Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells," J Med Chem. 56(10):3996-4016. PMCID: PMC3714011. PubMed
Cross, BM., Hack, A., Reinhardt, TA. and Rao, R., 2013, "SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation," PLoS One. ;8(6):e67348. PMCID: PMC3696057 PubMed
Whited, K., Baile, MG., Currier, P. and Claypool, SM., 2013, "Seven functional classes of Barth syndrome mutation," Hum Mol Genet. 1;22(3):483-92. PMCID: PMC3606006 PubMed

2012

Issigonis, M. and Matunis, E., 2012, "The Drosophila BCL6 homolog Ken and Barbie promotes somatic stem cell self-renewal in the testis niche," Dev Biol. 368(2):181-92. PMCID: PMC3402624 Pubmed
Huster, D., Kühne, A., Bhattacharjee, A., Raines, L., Jantsch, V., Noe, J., Schirrmeister, W., Sommerer, I., Sabri, O., Berr, F., Mössner, J., Stieger, B., Caca, K. and Lutsenko, S., 2012, "Diverse functional properties of Wilson disease ATP7B variants," Gastroenterology. 142(4), 947-956. PMCID: PMC3461965 Pubmed 
Hobbs, RP., Lessard, JC. and Coulombe, PA., 2012, "Keratin intermediate filament proteins - novel regulators of inflammation and immunity in skin," J Cell Sci.,125(Pt 22):5257-8. PMCID: PMC3561851 Pubmed
Clayton, AM., Cirimotich, CM., Dong, Y. and Dimopoulos, G., 2013, "Caudal is a negative regulator of the Anopheles IMD pathway that controls resistance to Plasmodium falciparum infection," Dev Comp Immunol. 39(4):323-32. PMCID: PMC3892953 Pubmed
Tamura, Y., Onguka, O., Itoh, K., Endo, T., Iijima, M., Claypool, SM. and Sesaki, H., 2012, "Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P," J Biol Chem. 287(52):43961-71. PMCID: PMC3527979Pubmed
Stevens, EL., Baugher, JD., Shirley, MD., Frelin, LP. and Pevsner, J., 2012, "Unexpected relationships and inbreeding in HapMap phase III populations," PLoS One. 7(11):e49575. PMCID: PMC3501496 Pubmed
Han, L., Ma, C., Liu, Q., Weng, HJ., Cui, Y., Tang, Z., Kim, Y., Nie, H., Qu, L., Patel, KN., Li, Z., McNeil, B., He, S., Guan, Y., Xiao, B., Lamotte, RH. and Dong, X., 2013, "A subpopulation of nociceptors specifically linked to itch," Nat Neurosci.16(2):174-82. PMCID: PMC3557753 Pubmed 
Wang, Y., Rattner, A., Zhou, Y., Williams, J., Smallwood, PM. and Nathans, J., 2012, "Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity," Cell. 151(6):1332-44, PMCID: PMC3535266  Pubmed 
Porter, JR., Burg, JS., Espenshade, PJ. and Iglesias, PA., 2012, "Identifying a static nonlinear structure in a biological system using noisy, sparse data," J Theor Biol. 300:232-41. PMCID: PMC3307847  Pubmed 
Phua, SC., Pohlmeyer, C. and Inoue, T., 2012, "Rapidly relocating molecules between organelles to manipulate small GTPase activity," ACS Chem Biol. 7(12):1950-5. PMCID: PMC3528809 PubMed
Mularoni, L., Zhou, Y., Bowen, T., Gangadharan, S., Wheelan, SJ. and Boeke, JD., 2012, "Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots," Genome Res. 22(4):693-703. doi: 10.1101/gr.129460.111. Epub 2012 Jan 4, PMCID: PMC3317151Pubmed 
Lessard, JC. and Coulombe, PA., 2012, "Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders," J Invest Dermatol,132(5):1384-91. PMCID: PMC3326191 Pubmed 
Tamura, Y., Onguka, O., Itoh, K., Endo, T., Iijima, M., Claypool, SM. and Sesaki, H., 2012, "Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P," J Biol Chem. 287(52):43961-71. PMCID: PMC3527979 Pubmed 
Ewald, AJ., Huebner, RJ., Palsdottir, H., Lee, JK., Perez, MJ., Jorgens, DM., Tauscher, AN., Cheung, KJ., Werb, Z. and Auer, M., 2012, "Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium," J Cell Sci. 125(Pt 11):2638-54. PMCID: PMC3403234  Pubmed 
Zhong, J., Kim, MS., Chaerkady, R., Wu, X., Huang, TC., Getnet, D., Mitchell, CJ., Palapetta, SM., Sharma, J., O’Meally, RN., Cole, RN., Yoda, A., Moritz, A., Loriaux, MM., Rush, J., Weinstock, DM., Tyner, JW. and Pandey, A., 2012, "TSLP signaling network revealed by SILAC-based phosphoproteomics," Mol Cell Proteomics. 11(6):M112.017764.PMCID: PMC3433886 Pubmed 
Shirley, MD., Baugher, JD., Stevens, EL., Tang, Z., Gerry, N., Beiswanger, CM., Berlin., DS and Pevsner, J., 2012, "Chromosomal variation in lymphoblastoid cell lines," Hum Mutat. 33(7):1075-86. PMCID: PMC3370055 Pubmed 
West-Foyle, H. and Robinson, DN., 2012, "Cytokinesis mechanics and mechanosensing," Cytoskeleton, 69(10):700-709. PMCID: PMC3477504 Pubmed 
Herb, BR., Wolschin, F., Hansen, KD., Aryee, MJ., Langmead, B., Irizarry, R., Amdam, GV., and Feinberg, AP., 2012, "Reversible switching between epigenetic states in honeybee behavioral subcastes," Nat Neurosci. 15(10):1371-3. PMCID: PMC3518384Pubmed 
Hatori, Y., Clasen, S., Hasan, NM., Barry, AN. and Lutsenko, S., 2012, "Functional partnership of the copper export machinery and glutathione balance in human cells," J Biol Chem. 2287(32):26678-87. PMCID: PMC3411007 Pubmed 
Zhu, H., Cox, E. and Qian, J.,2012, "Functional protein microarray as molecular decathlete: A versatile player in clinical proteomics," Proteomics Clin Appl. 6(11-12):548-62.  PMCID: PMC3600421 Pubmed
Rotty, JD. and Coulombe PA., 2012, "A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair," J Cell Biol,197(3):381-9. PMCID: PMC3341159  Pubmed
Darby, MM., Serebreni, L., Pan, X., Boeke, JD. and Corden, JL., 2011, "The Saccharomyces cerevisiae Nrd1-Nab3 transcription termination pathway acts in opposition to Ras signaling and mediates response to nutrient depletion," Mol Cell Biol., 32(10):1762-75. PMCID: PMC3347421Pubmed​ 
Ruch, TR. and Machamer, CE., 2012, "A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein," PLoS Pathog., 2012;8(5):e1002674. PMCID: PMC3343006  Pubmed 
Stevens, EL., Heckenberg, G., Baugher, JD., Roberson, ED., Downey, TJ. and Pevsner, J., 2012, "Consanguinity in Centre d'Étude du Polymorphisme Humain (CEPH) pedigrees," Eur J Hum Genet. 20(6):657-67. PMCID: PMC3355261 Pubmed  
Alammar Zaritsky, L., Gama, L. and Clements, JE., 2012, "Canonical type I IFN signaling in simian immunodeficiency virus-infected macrophages is disrupted by astrocyte-secreted CCL2," J Immunol. 188(8):3876-85. PMCID: PMC3343693 Pubmed 
Shoemaker, CJ. and Green, R., 2012, "Translation drives mRNA quality control," Nat Struct Mol Biol. 19(6):594-601. PMCID: PMC4299859 Pubmed 
Becker, T., Franckenberg, S., Wickles, S., Shoemaker, CJ., Anger, A.,  Armache, JP., Sieber, H., Ungewickell, C., Berninghausen, O., Dabarkov, I., Karcher, A., Thomm, M., Hopfner, KP., Green, R. and Beckmann, R., 2012, "Structural basis of highly conserved ribosome recycling in eukaryotes  and archaea," Nature. 482(7386):501-6. PMID: 22358840 Pubmed 
Simon, DN., Domaradzki, T., Hofmann, WA. and Wilson, KL., 2013, "Lamin A tail modification by SUMO1 is disrupted by familial partial lipodystrophy-causing mutations," Mol Biol Cell., 24(3):342-50. PMCID: PMC3564541  Pubmed 
Huster, D., Kühne, A., Bhattacharjee, A., Raines, L., Jantsch, V., Noe, J., Schirrmeister, W., Sommerer, I., Sabri, O., Berr, F., Mössner, J., Stieger, B., Caca, K. and Lutsenko, S., 2012, "Diverse functional properties of Wilson disease ATP7B variants," Gastroenterology. 142(4), 947-956. PMCID: PMC3461965 Pubmed 
Currier, DG., Polk, RC. and Reeves, RH., 2012, "A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome," Prog Brain Res. 197:223-36. PMCID: PMC4405118 Pubmed 

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