Christopher J. Potter

Christopher J. Potter

Associate Professor
Primary Appointment: 
Neuroscience
443-287-4151

855 N. Wolfe Street
Rangos 434
Baltimore MD 21205

Research topic: 

Insect Olfaction: Molecules, Neurons, and Behavior

The current research focus of my laboratory is investigating the olfactory system of Anopheles mosquitoes.

We have developed new strains of Anopheles mosquitoes, utilizing the Q-system we originally developed for use in Drosophila, to explore how living Anopheles mosquitoes respond to their olfactory environment. Current efforts are focused on exploring how insect repellents affect a mosquito’s sense of smell, from the neurons that are activated, to the receptors required, to the behaviors that are elicited. Other projects include (but are not limited to): investigating the dynamic regulation of mosquito odorant receptors, generating and characterizing knock-ins and mutants of mosquito olfactory receptors, and exploring biting behaviors.

We are always looking for motivated graduate students, so if any of the above sounds interesting, email me to learn more about the lab. Or visit our lab webpage in the link above!

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BCMB students currently in the lab:
Selected Publications: 

Afify A and Potter CJ (2020). Insect Repellents Mediate Species-Specific Olfactory Behaviours in Mosquitoes. Malaria Journal. https://malariajournal.biomedcentral.com/articles/10.1186/s12936-020-032....

Afify A, Betz JF, Riabinina O, Lahondère C, Potter CJ (2019). Commonly used insect repellents hide human odors from Anopheles mosquitoes. Current Biology. DOI:10.1016/j.cub.2019.09.007. https://www.cell.com/current-biology/fulltext/S0960-9822(19)31167-4

Maguire SE, Potter CJ (2019) Diet Drugs Trick Mosquitoes into Feeling Full. Trends in Pharmacol Sci S0165-6147(19)30093-8. https://www.sciencedirect.com/science/article/pii/S0165614719300938?via%...

Potter CJ (2019) Olfaction: Mosquitoes Love your Acid Odors. Current Biology 29(8), R282–R284. https://www.sciencedirect.com/science/article/pii/S0960982219303082

Chin SG, Maguire SE, Huoviala P, Jefferis GSXE, Potter CJ (2018) Olfactory Neurons and Brain Centers Directing Oviposition Decisions in Drosophila. Cell Reports 24, 1667-1678 https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31108-2

Potter CJ. (2018) Shining a Light on Olfactory Circuits. Neuron 98, 1061-1063 https://www.cell.com/neuron/fulltext/S0896-6273(18)30488-4

Riabinina, O, Task, D, Marr, E, Lin, C-C, Alford R, O'Brochta, DA, Potter, CJ (2016) Organization of Olfactory Centers in the Malaria Mosquito Anopheles gambiae. Nature Communications 7, 1–12. http://doi.org/10.1038/ncomms13010 Lin, C-C,

Potter, CJ (2016) Non-Mendelian Dominant Maternal Effects Caused by CRISPR/Cas9 Transgenic Components in Drosophila melanogaster. G3 Genes|Genomes|Genetics Early Online September 16, 2016, doi: 10.1534/g3.116.034884; http://www.g3journal.org/content/6/11/3685.full

Lin, C-C, Potter, CJ (2016) Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster. Genetics 203(4) 1613-1628; DOI: 10.1534/genetics.116.191783; http://www.genetics.org/content/203/4/1613 Lin, C-C,

Riabinina, O., Potter, C. J. (2016) Olfactory Behaviors Assayed by Computer Tracking Of Drosophila in a Four-quadrant Olfactometer. J. Vis. Exp. (114), e54346, doi:10.3791/54346 JoVE

Lin, C-C., Prokop-Prigge, KA, Preti, G and Potter CJ (2015) Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions. eLife. http://dx.doi.org/10.7554/eLife.08688

Lin, C-C. and Potter, CJ (2015) Re-classification of Drosophila melanogaster Trichoid and Intermediate Sensilla Using Fluorescence-guided Single Sensillum Recording. PLoS ONE, http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139675

Riabinina, O., Luginbuhl, D., Marr, E., Liu, S., Wu, M.N., Luo, L., and Potter, C.J (2015) Improved and expanded Q-system reagents for genetic manipulations. Nature Methods, 12:219-222. http://dx.doi.org/10.1038/nmeth.3250 Potter, CJ (2014) Stop the Biting: Targeting a Mosquito’s Sense of Smell (review). Cell 156:878-881.