Recent Publications




Bryan DS, Stack M, Krysztofiak K, Cichoń U, Thomas DG, Surcel A, Schiffhauer ES, Beckett MA, Khodarev NN, Xue L, Poli EC, Pearson AT, Posner MC, Robinson DN, Rock RS, Weichselbaum RR., 2020 “4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis,” Proc Natl Acad Sci U S A. 2020 Aug 26:202014639. doi: 10.1073/pnas.2014639117. Online ahead of print. PMID: 32848073 PubMed.  
Enam SU, Zinshteyn B, Goldman DH, Cassani M, Livingston NM, Seydoux G, Green R., 2020, “Puromycin reactivity does not accurately localize translation at the subcellular level.” Elife. 2020 Aug 26;9:e60303. doi: 10.7554/eLife.60303. Online ahead of print. PMID: 32844748 PubMed.  
Thorpe J, Frelin LP, McCann M, Pardo CA, Cohen BA, Comi AM, Pevsner J., 2020, “Identification of a mosaic activating mutation in GNA11 in atypical Sturge-Weber Syndrome.” J Invest Dermatol. 2020 Aug 6:S0022-202X(20)31955-2. doi: 10.1016/j.jid.2020.03.978. Online ahead of print. PMID: 32771470 PubMed.  
Ruan L, McNamara JT, Zhang X, Chang AC, Zhu J, Dong Y, Sun G, Peterson A, Na CH, Li R., 2020 “Solid-phase inclusion as a mechanism for regulating unfolded proteins in the mitochondrial matrix.” Sci Adv. 2020 Aug 5;6(32):eabc7288. doi: 10.1126/sciadv.abc7288. eCollection 2020 Aug. PMID: 32821848 PMCID: PMC7406381 PubMed.  
Mihaljević L, Urban S., 2020, “Decoding the Functional Evolution of an Intramembrane Protease Superfamily by Statistical Coupling Analysis.” Structure. 2020 Aug 10:S0969-2126(20)30279-3. doi: 10.1016/j.str.2020.07.015. Online ahead of print. PMID: 32795403 PubMed.  
Chin AC, Yovanno RA, Wied TJ, Gershman A, Lau AY. 2020, “D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2.” Structure. 2020 Jul 28:S0969-2126(20)30238-0. doi: 10.1016/j.str.2020.07.005. Online ahead of print. PMID: 32735769 PubMed.  
May MR, Bettridge JT, Desiderio S., 2020, "Binding and allosteric transmission of histone 3 Lys-4 trimethylation to the recombinase RAG-1 are separable functions of the RAG-2 PHD finger," J Biol Chem. 2020 Jul 3;295(27):9052-9060. doi: 10.1074/jbc.RA120.014382. PMCID: PMC7335790 PubMed.
Tan SY, Little HC, Sarver DC, Watkins PA, Wong GW., 2020 “CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression.” FEBS Lett. 2020 Aug 4. doi: 10.1002/1873-3468.13895. Online ahead of print. PMID: 32749667 PubMed.    
Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF., 2019, “SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL.” J Cell Biol. 2019 Jul 1;218(7):2185-2197. doi: 10.1083/jcb.201803041. PMCID: PMC6605807 PubMed.  
Poll BG, Cheema MU, Pluznick JL., 2020, “Gut Microbial Metabolites and Blood Pressure Regulation: Focus on SCFAs and TMAO.” Physiology (Bethesda). 2020 Jul 1;35(4):275-284. doi: 10.1152/physiol.00004.2020. PMID: 32490748 PubMed.  
Shubin CB, Greider CW., “The Role of Rif1 in telomere length regulation is separable from its role in origin firing.” Elife. 2020 Jun 29;9. pii: e58066. doi: 10.7554/eLife.58066. PMCID: PMC7371424 PubMed.  
Bian Q, Cheng YH, Wilson JP, Su EY, Kim DW, Wang H, Yoo S, Blackshaw S, Cahan P., 2020, "A single cell transcriptional atlas of early synovial joint development," Development. 2020 Jun 24. pii: dev.185777. doi: 10.1242/dev.185777. [Epub ahead of print] PMCID: PMC7390639 PubMed.
Wang TS, Coppens I, Saorin A, Brady NR, Hamacher-Brady A., 2020, "Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling," Dev Cell. 2020 Jun 22;53(6):627-645.e7. doi: 10.1016/j.devcel.2020.05.014. PubMed.  
Zhang R, Lee DM, Jimah JR, Gerassimov N, Yang C, Kim S, Luvsanjav D, Winkelman J, Mettlen M, Abrams ME, Kalia R, Keene P, Pandey P, Ravaux B, Kim JH, Ditlev JA, Zhang G, Rosen MK, Frost A, Alto NM, Gardel M, Schmid SL, Svitkina TM, Hinshaw JE, Chen EH., 2020, "Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein," Nat Cell Biol. 2020 Jun;22(6):674-688. doi: 10.1038/s41556-020-0519-7. PubMed.    
Timmons A, Fray E, Kumar M, Wu F, Dai W, Bullen CK, Kim P, Hetzel C, Yang C, Beg S, Lai J, Pomerantz JL, Yukl SA, Siliciano JD, Siliciano RF., 2020 “HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo.” Proc Natl Acad Sci U S A. 2020 Jun 22. pii: 201916290. doi: 10.1073/pnas.1916290117. PMID: 32571938 PubMed.
Zinshteyn B, Wangen JR, Hua B, Green R., 2020, "Nuclease-mediated depletion biases in ribosome footprint profiling libraries," RNA. 2020 Jun 5. pii: rna.075523.120. doi: 10.1261/rna.075523.120. PubMed.  
Gelsinger DR, Dallon E, Reddy R, Mohammad F, Buskirk AR, DiRuggiero J., 2020, "Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution," Nucleic Acids Res.2020 Jun 4;48(10):5201-5216. doi: 10.1093/nar/gkaa304 PMCID: PMC7261190 PubMed.    
Hunyara JL, Kolodkin AL., 2020, “Repurposing developmental mechanisms in the adult nervous system.” Curr Opin Genet Dev. 2020 May 30;65:14-21. doi: 10.1016/j.gde.2020.04.006. Review. PMID: 32485480 PubMed.  
Vasavda C, Ho BK, Snyder SH., 2020, “Ease restrictions on U.S. blood donations.” Science. 2020 May 29;368(6494):957. doi: 10.1126/science.abc2322. No abstract available. PMID: 32467382 PubMed.
Sadler E, Ryals MM, May LA, Martin D, Welsh N, Boger ET, Morell RJ, Hertzano R, Cunningham LL., 2020, “Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium.” Front Cell Neurosci. 2020 May 15;14:123. doi: 10.3389/fncel.2020.00123. eCollection 2020. PMCID: PMC7247426 PubMed.  
Lariviere PJ, Mahone CR, Santiago-Collazo G, Howell M, Daitch AK, Zeinert R, Chien P, Brown PJB, Goley ED., 2019, “An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation”, Curr Biol. 2019 May 6;29(9):1460-1470.e4. doi: 10.1016/j.cub.2019.03.066. PMCID: PMC6504580 PubMed.  
Cairns L, Patterson A, Weingartner KA, Koehler TJ, DeAngelis DR, Tripp KW, Bothner B, Kavran JM., 2020 May 1, “Biophysical characterization of SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila,” J Biol Chem. 295(18):6202-6213 doi: 10.1074/jbc.RA120.012679. PubMed.  
Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, Wong GW, Hankenson KD. 2020, “CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing,” J Orthop Res. 2020 May 01;38(5):996-1006. doi: 10.1002/jor.24553. Epub 2019 Dec 16. PMID: 31808575 PMCID: PMC7162724 PubMed.  
White CJ, Lee J, Choi J, Chu T, Scafidi S, Wolfgang MJ. 2020, “Determining the Bioenergetic Capacity for Fatty Acid Oxidation in the Mammalian Nervous System.” Mol Cell Biol. 2020 Apr 28;40(10):e00037-20. doi: 10.1128/MCB.00037-20. Print 2020 Apr 28. PMID: 32123009 PMCID: PMC7189099 PubMed.
Jiao Z, Cai H, Long Y, Sirka OK, Padmanaban V, Ewald AJ, Devreotes PN., 2020, “Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects,” Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4158-4168. doi: 10.1073/pnas.1917938117. Epub 2020 Feb 12. PubMed.
Jang Y, Elsayed Z, Eki R, He S, Du KP, Abbas T, Kai M., 2020, “Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites,” Proc Natl Acad Sci U S A. 2020 Feb 24. pii: 201913280. doi: 10.1073/pnas.1913280117. [Epub ahead of print] PubMed.  
Xu Z, Green B, Benoit N, Schatz M, Wheelan S, Cormack B., 2020, “De novo genome assembly of Candida glabrata reveals cell wall protein complement and structure of dispersed tandem repeat arrays,” Mol Microbiol. 2020 Feb 18. doi: 10.1111/mmi.14488 PubMed.  
Padmanaban V, Tsehay Y, Cheung KJ, Ewald AJ, Bader JS. 2020 Jan 21. “Between-tumor and within-tumor heterogeneity in invasive potential.” PLoS Comput Biol.;16(1):e1007464. doi: 10.1371/journal.pcbi.1007464. PMCID: PMC6994152. PubMed.  
Ruan L, Wang Y, Zhang X, Tomaszewski A, McNamara JT, Li R. 2020 Jan 13. “Mitochondria-Associated Proteostasis.” Annu Rev Biophys.. doi: 10.1146/annurev-biophys-121219-081604. PMID: 31928428. PubMed.  
Barrows JM, Sundararajan K, Bhargava A, Goley ED. 2020 Jan 13. “FtsA regulates Z-ring morphology and cell wall metabolism in an FtsZ C-terminal linker dependent manner in C. crescentus.” J Bacteriol. pii: JB.00693-19. doi: 10.1128/JB.00693-19. PMID: 31932314. PubMed.  
Dobrowolski M, Cave C, Levy-Myers R, Lee C, Park S, Choi BR, Xiao B, Yang W, Sockanathan S. 2020 Jan 23. “GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRα.” Development;147(2). pii: dev180695. doi: 10.1242/dev.180695. PMID: 31932351. PMCID: PMC6983723. PubMed.  
Maynard KR, Kardian A, Hill JL, Mai Y, Barry B, Hallock HL, Jaffe AE, Martinowich K. 2020 Jan 13. "TrkB signaling influences gene expression in cortistatin-expressing interneurons.” eNeuro.. pii: ENEURO.0310-19.2019. doi: 10.1523/ENEURO.0310-19.2019. PMID: 31941661. PubMed.  
Lee CS, Putnam A, Lu T, He S, Ouyang JPT, Seydoux G. 2020 Jan 24. “Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins.” Elife.;9. pii: e52896. doi: 10.7554/eLife.52896. PMID: 31975687. PubMed.  
Woldemeskel SA, Daitch AK, Alvarez L, Panis G, Zeinert R, Gonzalez D, Smith E, Collier J, Chien P, Cava F, Viollier PH, Goley ED. 2020 Jan 21 “The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter.” PLoS Genet.;16(1):e1008591. doi: 10.1371/journal.pgen.1008591. PMCID: PMC6994171 PubMed.  
Wangen JR, Green R. 2020 Jan 23. “Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. Elife.;9. pii: e52611. doi: 10.7554/eLife.52611. PMID: 31971508. PubMed.  
Putnam A, Cassani M, Smith J, Seydoux G. 2020 Jan 2. “Author Correction: A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos.” Nat Struct Mol Biol. doi: 10.1038/s41594-019-0367-y. PMID: 31896770. PubMed.  
Veltri AJ, D'Orazio KN, Green R. 2020 Jan 8. “Make or break: the ribosome as a regulator of mRNA decay.” Cell Res.. doi: 10.1038/s41422-019-0271-3. PMID: 31913358. PubMed.  
Renuse S, Madugundu AK, Jung JH, Byeon SK, Goldschmidt HL, Tahir R, Meyers D, Kim DI, Cutler J, Kim KP, Wu X, Huganir RL, Pandey A. 2020 Jan 13. “Signature Fragment Ions of Biotinylated Peptides.” J Am Soc Mass Spectrom. PMID: 31939678. PubMed.                    
Park EM, Scott PM, Clutario K, Cassidy KB, Zhan K, Gerber SA, Holland AJ. 2020 Jan 6. “WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication.” J Cell Biol.;219(1). pii: e201904203. doi: 10.1083/jcb.201904203. PMID: 31874114. PubMed.  


Howell M, Aliashkevich A, Sundararajan K, Daniel JJ, Lariviere PJ, Goley ED, Cava F, Brown PJB. 2019 Apr. “Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division.” Mol Microbiol.;111(4):1074-1092. doi: 10.1111/mmi.14212. Epub 2019 Mar 4. PMID: 30693575. PMCID: PMC6482847. PubMed.  
Rodriguez S, Little HC, Daneshpajouhnejad P, Shepard BD, Tan SY, Wolfe A, Cheema MU, Jandu S, Woodward OM, Talbot CC Jr, Berkowitz DE, Rosenberg AZ, Pluznick JL, Wong GW. 2019 Dec 26 “Late-onset renal hypertrophy and dysfunction in mice lacking CTRP1.” FASEB J. doi: 10.1096/fj.201900558RR. PMID: 31908037. PubMed.  
Mohammad F, Buskirk AR., 2019 Dec 20, “Protocol for Ribosome Profiling in Bacteria,” Bio Protoc.;9(24). pii: e3468. doi: 10.21769/BioProtoc.3468. PMCID: PMC7079819 PubMed  
Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. 2019 Dec. “Massive centriole production can occur in the absence of deuterosomes in multiciliated cells.” Nat Cell Biol.;21(12):1544-1552. doi: 10.1038/s41556-019-0427-x. PMID: 31792378. PMCID: PMC6913274. PubMed.  
Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, Wong GW, Hankenson KD. 2019 Dec 6. “CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing.” J Orthop Res..doi:10.1002/jor.24553. [Epub ahead of print]. PMID: 31808575. PubMed.  
Comert F, Greenwood A, Maramba J, Acevedo R, Lucas L, Kulasinghe T, Cairns LS, Wen Y, Fu R, Hammer J, Blazyk J, Sukharev S, Cotten ML, Mihailescu M., 2019, "The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels," J Biol Chem. 2019 Dec 6;294(49):18557-18570. doi: 10.1074/jbc.RA119.010232. PMCID: PMC6901303 PubMed  
Lee JH, Berger JM. 2019 Oct 30. “Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II.” Genes (Basel).;10(11). pii: E859. doi: 10.3390/genes10110859. Review. PMCID: PMC6896119. PubMed.  
Georgess D, Padmanaban V, Sirka OK, Coutinho K, Choi A, Frid G, Neumann NM, Inoue T, Ewald AJ.  2019 Nov 1 “Twist1-induced epithelial dissemination requires Prkd1 signaling.” Cancer Res. pii: canres.3241.2018. doi: 10.1158/0008-5472.CAN-18-3241. PMID: 31676574. PubMed.  
Allen J, Hao S, Sears CL, Timp W. 2019 May 21. “Epigenetic Changes Induced by Bacteroides fragilis Toxin” Infect Immun.;87(6). pii: e00447-18. doi: 10.1128/IAI.00447-18. Print 2019 Jun. PMID: 30885929. PMCID: PMC6529667. PubMed.  
Keener R, Connelly CJ, Greider CW. 2019 Dec. “Tel1 Activation by the MRX Complex Is Sufficient for Telomere Length Regulation but Not for the DNA Damage Response in Saccharomyces cerevisiae. Genetics. 213(4):1271-1288. doi: 10.1534/genetics.119.302713 PMCID: PMC6893380. PubMed  
Bowman CE, Selen Alpergin ES, Cavagnini K, Smith DM, Scafidi S, Wolfgang MJ. 2019 Oct 29. “Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress.” Cell Rep.;29(5):1299-1310.e3. doi: 10.1016/j.celrep.2019.09.053. PMID: 31665641. PubMed.