Recent Publications


Cairns L, Patterson A, Weingartner KA, Koehler TJ, DeAngelis DR, Tripp KW, Bothner B, Kavran JM., 2020 May 1, “Biophysical characterization of SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila,” J Biol Chem. 295(18):6202-6213 doi: 10.1074/jbc.RA120.012679. PubMed  
White CJ, Lee J, Choi J, Chu T, Scafidi S, Wolfgang MJ., 2020 Apr 28, “Determining the bioenergetic capacity for fatty acid oxidation in the mammalian nervous system.” Mol Cell Biol. 40(10) pii: MCB.00037-20. doi: 10.1128/MCB.00037-20. PubMed
Jiao Z, Cai H, Long Y, Sirka OK, Padmanaban V, Ewald AJ, Devreotes PN., 2020, “Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects,” Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4158-4168. doi: 10.1073/pnas.1917938117. Epub 2020 Feb 12. PubMed
Jang Y, Elsayed Z, Eki R, He S, Du KP, Abbas T, Kai M., 2020, “Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites,” Proc Natl Acad Sci U S A. 2020 Feb 24. pii: 201913280. doi: 10.1073/pnas.1913280117. [Epub ahead of print] PubMed  
Xu Z, Green B, Benoit N, Schatz M, Wheelan S, Cormack B., 2020, “De novo genome assembly of Candida glabrata reveals cell wall protein complement and structure of dispersed tandem repeat arrays,” Mol Microbiol. 2020 Feb 18. doi: 10.1111/mmi.14488 PubMed  
Padmanaban V, Tsehay Y, Cheung KJ, Ewald AJ, Bader JS. 2020 Jan 21. “Between-tumor and within-tumor heterogeneity in invasive potential.” PLoS Comput Biol.;16(1):e1007464. doi: 10.1371/journal.pcbi.1007464. PMCID: PMC6994152. PubMed.  
Ruan L, Wang Y, Zhang X, Tomaszewski A, McNamara JT, Li R. 2020 Jan 13. “Mitochondria-Associated Proteostasis.” Annu Rev Biophys.. doi: 10.1146/annurev-biophys-121219-081604. PMID: 31928428. PubMed.  
Barrows JM, Sundararajan K, Bhargava A, Goley ED. 2020 Jan 13. “FtsA regulates Z-ring morphology and cell wall metabolism in an FtsZ C-terminal linker dependent manner in C. crescentus.” J Bacteriol. pii: JB.00693-19. doi: 10.1128/JB.00693-19. PMID: 31932314. PubMed.  
Dobrowolski M, Cave C, Levy-Myers R, Lee C, Park S, Choi BR, Xiao B, Yang W, Sockanathan S. 2020 Jan 23. “GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRα.” Development;147(2). pii: dev180695. doi: 10.1242/dev.180695. PMID: 31932351. PMCID: PMC6983723. PubMed.  
Maynard KR, Kardian A, Hill JL, Mai Y, Barry B, Hallock HL, Jaffe AE, Martinowich K. 2020 Jan 13. "TrkB signaling influences gene expression in cortistatin-expressing interneurons.” eNeuro.. pii: ENEURO.0310-19.2019. doi: 10.1523/ENEURO.0310-19.2019. PMID: 31941661. PubMed.  
Lee CS, Putnam A, Lu T, He S, Ouyang JPT, Seydoux G. 2020 Jan 24. “Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins.” Elife.;9. pii: e52896. doi: 10.7554/eLife.52896. PMID: 31975687. PubMed.  
Woldemeskel SA, Daitch AK, Alvarez L, Panis G, Zeinert R, Gonzalez D, Smith E, Collier J, Chien P, Cava F, Viollier PH, Goley ED. 2020 Jan 21 “The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter.” PLoS Genet.;16(1):e1008591. doi: 10.1371/journal.pgen.1008591. PMCID: PMC6994171 PubMed  
Wangen JR, Green R. 2020 Jan 23. “Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. Elife.;9. pii: e52611. doi: 10.7554/eLife.52611. PMID: 31971508. PubMed  
Putnam A, Cassani M, Smith J, Seydoux G. 2020 Jan 2. “Author Correction: A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos.” Nat Struct Mol Biol. doi: 10.1038/s41594-019-0367-y. PMID: 31896770. PubMed  
Veltri AJ, D'Orazio KN, Green R. 2020 Jan 8. “Make or break: the ribosome as a regulator of mRNA decay.” Cell Res.. doi: 10.1038/s41422-019-0271-3. PMID: 31913358. PubMed  
Renuse S, Madugundu AK, Jung JH, Byeon SK, Goldschmidt HL, Tahir R, Meyers D, Kim DI, Cutler J, Kim KP, Wu X, Huganir RL, Pandey A. 2020 Jan 13. “Signature Fragment Ions of Biotinylated Peptides.” J Am Soc Mass Spectrom. PMID: 31939678. PubMed.                    
Park EM, Scott PM, Clutario K, Cassidy KB, Zhan K, Gerber SA, Holland AJ. 2020 Jan 6. “WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication.” J Cell Biol.;219(1). pii: e201904203. doi: 10.1083/jcb.201904203. PMID: 31874114. PubMed.  


Rodriguez S, Little HC, Daneshpajouhnejad P, Shepard BD, Tan SY, Wolfe A, Cheema MU, Jandu S, Woodward OM, Talbot CC Jr, Berkowitz DE, Rosenberg AZ, Pluznick JL, Wong GW. 2019 Dec 26 “Late-onset renal hypertrophy and dysfunction in mice lacking CTRP1.” FASEB J. doi: 10.1096/fj.201900558RR. PMID: 31908037. PubMed.  
Howell M, Aliashkevich A, Sundararajan K, Daniel JJ, Lariviere PJ, Goley ED, Cava F, Brown PJB. 2019 Apr. “Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division.” Mol Microbiol.;111(4):1074-1092. doi: 10.1111/mmi.14212. Epub 2019 Mar 4. PMID: 30693575. PMCID: PMC6482847. PubMed.  
Mohammad F, Buskirk AR., 2019 Dec 20, “Protocol for Ribosome Profiling in Bacteria,” Bio Protoc.;9(24). pii: e3468. doi: 10.21769/BioProtoc.3468. PMCID: PMC7079819 PubMed  
Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. 2019 Dec. “Massive centriole production can occur in the absence of deuterosomes in multiciliated cells.” Nat Cell Biol.;21(12):1544-1552. doi: 10.1038/s41556-019-0427-x. PMID: 31792378. PMCID: PMC6913274. PubMed.  
Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, Wong GW, Hankenson KD. 2019 Dec 6. “CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing.” J Orthop Res..doi:10.1002/jor.24553. [Epub ahead of print]. PMID: 31808575. PubMed.  
Rodriguez S, Stewart AN, Lei X, Cao X, Little HC, Fong V, Sarver DC, Wong GW. 2019 Nov 5. “PRADC1: a novel metabolic-responsive secretory protein that modulates physical activity and adiposity.” FASEB J.:fj201901279R. doi: 10.1096/fj.201901279R. PMID: 31689374. PubMed.  
Lee JH, Berger JM. 2019 Oct 30. “Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II.” Genes (Basel).;10(11). pii: E859. doi: 10.3390/genes10110859. Review. PMCID: PMC6896119. PubMed.  
Georgess D, Padmanaban V, Sirka OK, Coutinho K, Choi A, Frid G, Neumann NM, Inoue T, Ewald AJ.  2019 Nov 1 “Twist1-induced epithelial dissemination requires Prkd1 signaling.” Cancer Res. pii: canres.3241.2018. doi: 10.1158/0008-5472.CAN-18-3241. PMID: 31676574. PubMed.  
Le TT, Gao X, Park SH, Lee J, Inman JT, Lee JH, Killian JL, Badman RP, Berger JM, Wang MD. 2019 Oct 17. “Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity.” Cell.;179(3):619-631.e15. doi: 10.1016/j.cell.2019.09.034. PMID: 31626768. PubMed  
Allen J, Hao S, Sears CL, Timp W. 2019 May 21. “Epigenetic Changes Induced by Bacteroides fragilis Toxin” Infect Immun.;87(6). pii: e00447-18. doi: 10.1128/IAI.00447-18. Print 2019 Jun. PMID: 30885929. PMCID: PMC6529667. PubMed.  
Keener R, Connelly CJ, Greider CW. 2019 Dec. “Tel1 Activation by the MRX Complex Is Sufficient for Telomere Length Regulation but Not for the DNA Damage Response in Saccharomyces cerevisiae. Genetics. 213(4):1271-1288. doi: 10.1534/genetics.119.302713 PMCID: PMC6893380. PubMed  
Bowman CE, Selen Alpergin ES, Cavagnini K, Smith DM, Scafidi S, Wolfgang MJ. 2019 Oct 29. “Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress.” Cell Rep.;29(5):1299-1310.e3. doi: 10.1016/j.celrep.2019.09.053. PMID: 31665641. PubMed.  
Comert F, Greenwood A, Maramba J, Acevedo R, Lucas L, Kulasinghe T, Cairns LS, Wen Y, Fu R, Hammer J, Blazyk J, Sukharev S, Cotten ML, Mihailescu M. 2019 Oct 16.“The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels” J Biol Chem. pii: jbc.RA119.010232. doi: 10.1074/jbc.RA119.010232. [Epub ahead of print] PMID: 31619519. PubMed
Kothari P, Johnson C, Sandone C, Iglesias PA, Robinson DN. 2019 Sep 2. “How the mechanobiome drives cell behavior, viewed through the lens of control theory.” J Cell Sci. 132(17). pii: jcs234476. doi: 10.1242/jcs.234476. Review. PMID: 31477578. PubMed.  
Frandolig JE, Matney CJ, Lee K, Kim J, Chevée M, Kim SJ, Bickert AA, Brown SP. 2019 Sep 17. “The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina.” Cell Rep. 28(12):3131-3143.e5. doi: 10.1016/j.celrep.2019.08.048. PMID: 31533036. PubMed.  
Padmanaban V, Krol I, Suhail Y, Szczerba BM, Aceto N, Bader JS, Ewald AJ. 2019 Sep. “E-cadherin is required for metastasis in multiple models of breast cancer.” Nature. 573(7774):439-444. doi: 10.1038/s41586-019-1526-3. Epub 2019 Sep 4. PMID: 31485072. PubMed.  
Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, Gordon M, Meirman R, Millan-Zambrano G, Ayestaran I, Salguero I, Sharan R, Li R, Kupiec M, Jackson SP. 2019 Sep. “Genome architecture and stability in the Saccharomyces cerevisiae knockout collection.” Nature. 573(7774):416-420. doi: 10.1038/s41586-019-1549-9. PMCID: PMC6774800. PubMed.  
Tan Y, Cahan P. 2019 Aug 28. “SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species.” Cell Syst.;9(2):207-213.e2. doi: 10.1016/j.cels.2019.06.004. Epub 2019 Jul 31. PMID: 31377170. PMCID: PMC6715530.  PubMed  
Vissers C, Kageyama R. 2019 Aug 19. “Bursting the Notch Bubble: New Insights into In Vivo Transcriptional Dynamics.” Dev Cell.;50(4):393-394. doi: 10.1016/j.devcel.2019.07.028. PMID: 31430449. PubMed.  
Pike AM, Strong MA, Ouyang JPT, Greider CW. 2019 Aug 5. “TIN2 functions with TPP1/POT1 to stimulate telomerase processivity.” Mol Cell Biol.. pii: MCB.00593-18. doi: 10.1128/MCB.00593-18. PMCID: PMC6791651. PubMed  
Wang Z, Hutcherson SM, Yang C, Jattani RP, Tritapoe JM, Yang YK, Pomerantz JL. J Biol Chem. 2019 Aug 7. “Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling.” pii: jbc.RA119.009551. doi: 10.1074/jbc.RA119.009551. PMID: 31391255. PubMed  
Ouyang JPT, Folkmann A, Bernard L, Lee CY, Seroussi U, Charlesworth AG, Claycomb JM, Seydoux G. 2019 Aug 6. “P Granules Protect RNA Interference Genes from Silencing by piRNAs.” Dev Cell.. pii: S1534-5807(19)30632-X. doi: 10.1016/j.devcel.2019.07.026. PMID: 31402283. PubMed.  
Pundir P, Liu R, Vasavda C, Serhan N, Limjunyawong N, Yee R, Zhan Y, Dong X, Wu X, Zhang Y, Snyder SH, Gaudenzio N, Vidal JE, Dong X. 2019 Jul 10. “A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity.” Cell Host Microbe.;26(1):114-122.e8. doi: 10.1016/j.chom.2019.06.003. Epub 2019 Jul 2. PMID: 31278040. PMCID: PMC6649664. PubMed.  
Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, Snyder SH. 2019 Jul 23. “Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.” Cell Chem Biol. pii: S2451-9456(19)30218-1. doi: 10.1016/j.chembiol.2019.07.006. [Epub ahead of print] PMID: 31353321. PubMed.  
Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF. 2019 Jul 10. “The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.” Cell Host Microbe.;26(1):73-85.e4. doi: 10.1016/j.chom.2019.06.005. PMID: 31295427. PMCID: PMC6724192 PubMed.  
Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC. 2019 Jul 23. “FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.” Cell Rep.;28(4):845-854.e5. doi: 10.1016/j.celrep.2019.06.072. PMID: 31340148. PubMed.  
Hayward D, Kouznetsova VL, Pierson HE, Hasan NM, Guzman ER, Tsigelny IF, Lutsenko S. 2019 Jul 23. “ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.” J Biol Chem.. pii: jbc.RA119.008231. doi: 10.1074/jbc.RA119.008231. [Epub ahead of print]. PMID: 31337707. PubMed.  
Surcel A, Schiffhauer ES, Thomas DG, Zhu Q, DiNapoli KT, Herbig M, Otto O, West-Foyle H, Jacobi A, Kräter M, Plak K, Guck J, Jaffee EM, Iglesias PA, Anders RA, Robinson DN. 2019 Jul 29. “Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14.” Cancer Res.. pii: canres.3131.2018. doi: 10.1158/0008-5472.CAN-18-3131. [Epub ahead of print] PMID: 31358530. PubMed.  
Johnson DM, Andrew DJ. 2019 Jun 26. “Role of tbc1 in Drosophila embryonic salivary glands.” BMC Mol Cell Biol. 20(1):19. doi: 10.1186/s12860-019-0198-z. PMCID: PMC6595604. PubMed.  
Allen J, Sears CL. 2019 Feb 25. “Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development.” Genome Med. 20(1):19. doi: 10.1186/s12860-019-0198-z. PMID: 30803449. PMCID: PMC6388476. PubMed  
Zhu L*, Liao SE*, Fukunaga R. 2019 Jun 23. “Drosophila Regnase-1 RNase is required for mRNA and miRNA profile remodelling during larva-to-adult metamorphosis.” RNA Biol. 1-15. doi: 10.1080/15476286.2019.1630799. [Epub ahead of print], PMCID: PMC6542536, *equal contribution. PubMed  
Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF. 2019 Jun 13. “SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL.” J Cell Biol. pii: jcb.201803041. doi: 10.1083/jcb.201803041. [Epub ahead of print]. PMID: 31197030. PubMed.  
D'Orazio KN, Wu CC, Sinha N, Loll-Krippleber R, Brown GW, Green R. 2019 Jun 20. “The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay.” Elife. 8. pii: e49117. doi: 10.7554/eLife.49117. PMCID: PMC6598757. PubMed.