James M. Berger

Research Interests: My laboratory’s research is focused on understanding how multi-subunit assemblies use ATP for overcoming topological challenges within the chromosome and controlling the flow of genetic information. We are particularly interested in developing mechanistic models that explain how...

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Robert N. Cole

Our research is highly collaborative and focuses on developing, optimizing and applying innovative mass spectrometry strategies to reveal the proteins, their modifications, interactomes and adductomes in modulating or monitoring human health and disease. Ongoing research: Albumin Adductome: Air pollution...

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Douglas Robinson

Multi-cellular living organisms grow from single cells into multicellular, complex systems composed of highly diverse cell-types organized into tissues, which in turn form organs and organ systems. To organize and maintain this complex architecture, the organism must undergo constant...

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Katherine Wilson

Within each human cell is a NUCLEUS, ‘mothership’ of the human genome and still the least-understood cellular structure. Chromosomes are enclosed by the nuclear envelope (NE) and communicate with the cytoplasm through Nuclear Pore Complexes (NPCs). The inner and...

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Sergi Regot

A fundamental property of living cells is their extraordinary ability to sense and respond to a changing environment. In higher eukaryotes, malfunctioning of signaling networks has many devastating consequences such as cancer, diabetes or autoimmunity. Such consequences arise from...

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Patrick Cahan

My lab is an interdisciplinary group that devises and experimentally tests computational tools to explore cell type identity and its molecular underpinnings. A unifying component of our research is the gene regulatory network (GRN). GRNs are programs encoded in...

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Rajini Rao

The Rao laboratory studies the role of novel ion transporters in human health and disease. One project focuses on the calcium signaling in breast cancer. We showed that an isoform of the secretory pathway Ca2+-ATPase, SPCA2, interacts with ion...

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Mollie K. Meffert

How are gene programs regulated to modify the brain during experience and disease? The Meffert lab studies molecular mechanisms underlying enduring changes in brain function. We are interested in understanding how programs of gene expression are coordinated and maintained...

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Joel L. Pomerantz

My laboratory is interested in the molecular mechanisms by which cells interpret signals from their environment that instruct them to proliferate, differentiate, or die by apoptosis. This process is of fundamental importance in the development and function of the...

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Winston Timp

My lab’s focus is in the development and application of sequencing technologies to gain a deeper understanding of biology and a more accurate set of clinical tools for human disease. We integrate biophysics, molecular biology and computational biology to...

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