Deborah Andrew

We study how epithelial tubular organs – which are essential to life in all multicellular organisms – form and specialize. Using the simple unbranched tubes of the Drosophila salivary gland and the beautifully branched tubular network of the Drosophila...

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Mollie K. Meffert

The goal of the Meffert lab is to gain a mechanistic understanding of how selective gene programs are recruited and maintained to modify the nervous system during development, experience-dependent plasticity, and in injury or disease.  Rather than focusing on...

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Joel L. Pomerantz

My laboratory is interested in the molecular mechanisms by which cells interpret signals from their environment that instruct them to proliferate, differentiate, or die by apoptosis. This process is of fundamental importance in the development and function of the...

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Joshua Modell

CRISPR-Cas loci serve as acquired immune systems which protect their bacterial and archaeal hosts from viruses and plasmids. CRISPR immunity occurs in two phases: First, short DNA segments from foreign invaders are captured and inserted into the CRISPR locus...

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Winston Timp

My lab’s focus is on the development and application of sequencing technologies to gain a deeper understanding of biology and a more accurate set of clinical tools for human disease. Our research integrates the principles of biophysics, molecular biology,...

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Anthony K. L. Leung

Laboratory of ADP-ribosylation in RNA Biology Our research program focuses on how gene regulation impacts diseases states, including cancer, neurodegeneration and virus infection. Recent research focus includes a druggable protein modification called poly(ADP-ribose). Poly(ADP-ribose) polymerase (PARP) inhibitors are currently...

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Scott Bailey

Research in my laboratory focuses on the molecular basis of the processes that relate to protein nucleic acid interaction. The strategy that we use is based primarily on structural studies using X-ray crystallography, for which I have extensive training....

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Photo of Keri Martinowich

Keri Martinowich

Even among similar cell types, differences in synaptic connectivity and activity patterns render these populations functionally and molecularly distinct. While early cell type-specific investigations obtained molecular profiles on the basis of cell-type markers,   molecular genetic tools now allow researchers...

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Carl Wu

We are interested in the biochemical principles that govern chromatin structure and gene expression. Chromatin is the native complex of DNA and histone proteins in nucleosome arrays, associated with nonhistone proteins and RNA. Chromatin has an important role in...

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