Carl Wu

We are interested in the biochemical principles that govern chromatin structure and gene expression. Chromatin is the native complex of DNA and histone proteins in nucleosome arrays, associated with nonhistone proteins and RNA. Chromatin has an important role in...

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Joshua Modell

CRISPR-Cas loci serve as acquired immune systems which protect their bacterial and archaeal hosts from viruses and plasmids. CRISPR immunity occurs in two phases: First, short DNA segments from foreign invaders are captured and inserted into the CRISPR locus...

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Winston Timp

My lab’s focus is on the development and application of sequencing technologies to gain a deeper understanding of biology and a more accurate set of clinical tools for human disease. Our research integrates the principles of biophysics, molecular biology,...

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