Chad Hicks


BS, Gonzaga University

Wolberger Lab

2024

Associated BCMB Faculty Member(s)

Name Lab Website
Cynthia Wolberger Lab website

Publications

  • Rahman S, Hicks CW, Gwizdala A, Wolberger C., 2025, Mechanism of USP21 autoinhibition and histone H2AK119 deubiquitination, Sci Adv., 11(41):eady2604. doi: 10.1126/sciadv.ady2604. PMCID: PMC12513422  PubMed
  • Hicks CW, Gliech CR, Rahman S, Zhang X, Eneim AS, Vasquez SJ, Holland AJ, Wolberger C., 2025, Haspin kinase binds to a nucleosomal DNA supergroove, Nat Struct Mol Biol., 32(6):1030-1037. doi: 10.1038/s41594-025-01502-y. PMCID: PMC12170164  PubMed
  • Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C., 2024, Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch, Nucleic Acids Res., 52(16):9978-9995. doi: 10.1093/nar/gkae698. Erratum in: Nucleic Acids Res. 2024 Sep 01:gkae751. doi: 10.1093/nar/gkae751. PMCID: PMC11381367  PubMed
  • Zhao F, Hicks CW, Wolberger C., 2023, Mechanism of histone H2B monoubiquitination by Bre1, Nat Struct Mol Biol., doi: 10.1038/s41594-023-01137-x. PMID: 37872231  PubMed
  • Fields JK, Hicks CW, Wolberger C., 2023, Diverse modes of regulating methyltransferase activity by histone ubiquitination, Curr Opin Struct Biol., 82:102649. doi: 10.1016/j.sbi.2023.102649. PMID: 37429149  PubMed

  • Worden EJ, Hoffmann NA, Hicks CW, Wolberger C. 2019 Mar 7. “Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.” Cell.;176(6):1490-1501.e12. doi: 10.1016/j.cell.2019.02.002. Epub 2019 Feb 11. PMID: 30765112. PMCID: PMC6498860. PubMed.

Awards and Distinctions

  • 2021 NIH F31 Predoctoral Fellowship