Recent Publications

Board NL, Moskovljevic M, Wu F, Siliciano RF, Siliciano JD., 2021, Engaging innate immunity in HIV-1 cure strategies, Nat Rev Immunol., doi: 10.1038/s41577-021-00649-1. PMID: 34824401  PubMed

Lyu P, Hoang T, Santiago CP, Thomas ED, Timms AE, Appel H, Gimmen M, Le N, Jiang L, Kim DW, Chen S, Espinoza DF, Telger AE, Weir K, Clark BS, Cherry TJ, Qian J, Blackshaw S., 2021,Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina, Cell Rep., 37(7):109994. doi: 10.1016/j.celrep.2021.109994. PMID: 34788628  PubMed

Wong X, Hoskins VE, Melendez-Perez AJ, Harr JC, Gordon M, Reddy KL., 2021, Lamin C is required to establish genome organization after mitosis, Genome Biol., 22(1):305. doi: 10.1186/s13059-021-02516-7. PMCID: PMC8591896  PubMed

Sholes SL, Karimian K, Gershman A, Kelly TJ, Timp W, Greider CW., 2021, Chromosome-specific telomere lengths and the minimal functional telomere revealed by nanopore sequencing, Genome Res., gr.275868.121. doi: 10.1101/gr.275868.121. PMID: 34702734  PubMed

Huang L, Bichsel C, Norris A, Thorpe J, Pevsner J, Alexandrescu S, Pinto A, Zurakowski D, Kleiman RJ, Sahin M, Greene AK, Bischoff J., 2021, Endothelial GNAQ p.R183Q Increases ANGPT2 (Angiopoietin-2) and Drives Formation of Enlarged Blood Vessels, Arterioscler Thromb Vasc Biol., ATVBAHA121316651. doi: 10.1161/ATVBAHA.121.316651. PMID: 34670408  PubMed

DiNapoli KT, Robinson DN, Iglesias PA., 2021, A mesoscale mechanical model of cellular interactions, Biophys J., S0006-3495(21)00880-8. doi: 10.1016/j.bpj.2021.10.021. PMID: 34687718.  PubMed

Tower RJ, Li Z, Cheng YH, Wang XW, Rajbhandari L, Zhang Q, Negri S, Uytingco CR, Venkatesan A, Zhou FQ, Cahan P, James AW, Clemens TL., 2021, Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling, Proc Natl Acad Sci U S A, 118(42):e2103087118. doi: 10.1073/pnas.2103087118. PMCID: PMC8545472  PubMed

McGuire MR, Mukhopadhyay D, Myers SL, Mosher EP, Brookheart RT, Kammers K, Sehgal A, Selen ES, Wolfgang MJ, Bumpus NN, Espenshade PJ., 2021, Progesterone receptor membrane component 1 (PGRMC1) binds and stabilizes cytochromes P450 through a heme-independent mechanism, J Biol Chem., 101316. doi: 10.1016/j.jbc.2021.101316. PMID: 34678314  PubMed

Wier E, Asada M, Wang G, Alphonse MP, Li A, Hintelmann C, Sweren E, Youn C, Pielstick B, Ortines R, Lyu C, Daskam M, Miller LS, Archer NK, Garza LA., 2021, Neutrophil extracellular traps impair regeneration, J Cell Mol Med., doi: 10.1111/jcmm.16896. PMID: 34623736  PubMed

Tran MN, Maynard KR, Spangler A, Huuki LA, Montgomery KD, Sadashivaiah V, Tippani M, Barry BK, Hancock DB, Hicks SC, Kleinman JE, Hyde TM, Collado-Torres L, Jaffe AE, Martinowich K., 2021, Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain, Neuron., 109(19):3088-3103.e5. doi: 10.1016/j.neuron.2021.09.001. PMCID: PMC8564763  PubMed

Guy B, Zhang JS, Duncan LH, Johnston RJ Jr., 2021, Human neural organoids: Models for developmental neurobiology and disease, Dev Biol., 478:102-121. doi: 10.1016/j.ydbio.2021.06.012. PMCID: PMC8364509  PubMed

Sell GL, Xin W, Cook EK, Zbinden MA, Schaffer TB, O’Meally RN, Cole RN, Margolis SS., 2021, Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice, Sci Rep., 11(1):19414. doi: 10.1038/s41598-021-97898-w. PMCID: PMC8484563.  PubMed

Vevea JD, Kusick GF, Courtney KC, Chen E, Watanabe S, Chapman ER., 2021, Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons, Elife, 10:e67261. doi: 10.7554/eLife.67261. PMCID: PMC8452306. 2021 PubMed

Lee JH, Mosher EP, Lee YS, Bumpus NN, Berger JM., 2021, Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites, Cell Chem Biol., S2451-9456(21)00403-7. doi: 10.1016/j.chembiol.2021.08.014. PMID: 34529934  PubMed

Poll BG, Xu J, Gupta K, Shubitowski TB, Pluznick JL., 2021, Olfactory receptor 78 modulates renin but not baseline blood pressure, Physiol Rep., (18):e15017. doi: 10.14814/phy2.15017. PMCID: PMC8455973  PubMed

Tahir R, Madugundu AK, Udainiya S, Cutler JA, Renuse S, Wang L, Pearson NA, Mitchell CJ, Mahajan N, Pandey A, Wu X., 2021, Proximity-Dependent Biotinylation to Elucidate the Interactome of TNK2 Nonreceptor Tyrosine Kinase, J Proteome Res., 20(9):4566-4577. doi: 10.1021/acs.jproteome.1c00551. Epub 2021 Aug 24. PMID: 34428048.  PubMed

Hutcherson SM, Bedsaul JR, Pomerantz JL., 2021, Pathway-Specific Defects in T, B, and NK Cells and Age-Dependent Development of High IgE in Mice Heterozygous for a CADINS-Associated Dominant NegativeCARD11 Allele, J Immunol., 207(4):1150-1164. doi: 10.4049/jimmunol.2001233, PMCID: PMC8355193. PubMed

Wang S, Latallo MJ, Zhang Z, Huang B, Bobrovnikov DG, Dong D, Livingston NM, Tjoeng W, Hayes LR, Rothstein JD, Ostrow LW, Wu B, Sun S., 2021, Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD, Nat Commun., 12(1):4908. doi: 10.1038/s41467-021-25082-9, PMCID: PMC8363653.  PubMed

Masuda I, Hwang JY, Christian T, Maharjan S, Mohammad F, Gamper H, Buskirk AR, Hou YM., 2021, Loss of N¹-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression, Elife, 10:e70619. doi: 10.7554/eLife.70619, PMCID: PMC8384417. PubMed

Coyne AN, Baskerville V, Zaepfel BL, Dickson DW, Rigo F, Bennett F, Lusk CP, Rothstein JD., 2021, Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS, Sci Transl Med., 13(604):eabe1923. doi: 10.1126/scitranslmed.abe1923, PMID: 34321318.  PubMed

Eagles NJ, Burke EE, Leonard J, Barry BK, Stolz JM, Huuki L, Phan BN, Serrato VL, Gutiérrez-Millán E, Aguilar-Ordoñez I, Jaffe AE, Collado-Torres L., 2021, Correction to: SPEAQeasy: a scalable pipeline for expression analysis and quantification for R/bioconductor‑powered RNA‑seq analyses. BMC Bioinformatics, 22(1):381. doi: 10.1186/s12859-021-04283-5. Erratum for: BMC Bioinformatics. 2021 May 1;22(1):224. PMCID: PMC8299680.  PubMed

Zaepfel BL, Rothstein JD., 2021, RNA Is a Double-Edged Sword in ALS Pathogenesis, Front Cell Neurosci., 15:708181. doi: 10.3389/fncel.2021.708181, PMCID: PMC8326408. PubMed

Saba JA, Liakath-Ali K, Green R, Watt FM., 2021, Translational control of stem cell function, Nat Rev Mol Cell Biol., doi: 10.1038/s41580-021-00386-2. Epub ahead of print. PMID: 34272502.  PubMed

Sharma J, Du M, Wong E, Mutyam V, Li Y, Chen J, Wangen J, Thrasher K, Fu L, Peng N, Tang L, Liu K, Mathew B, Bostwick RJ, Augelli-Szafran CE, Bihler H, Liang F, Mahiou J, Saltz J, Rab A, Hong J, Sorscher EJ, Mendenhall EM, Coppola CJ, Keeling KM, Green R, Mense M, Suto MJ, Rowe SM, Bedwell DM., 2021, A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion, Nat Commun., 12(1):4358. doi: 10.1038/s41467-021-24575-x,  PMCID: PMC8285393. PubMed

Jeon SM, Chang D, Geske A, Ginty DD, Caterina MJ., 2021, Sex-Dependent Reduction in Mechanical Allodynia in the Sural-Sparing Nerve Injury Model in Mice Lacking Merkel Cells, J Neurosci., 41(26):5595-5619. doi: 10.1523/JNEUROSCI.1668-20.2021. PMCID: PMC8244979  PubMed

Narkar A, Johnson BA, Li R., 2021, Complex interplay between p53 and chromosome stability, Mol Cell Oncol., 8(4):1938479. doi: 10.1080/23723556.2021.1938479. PMCID: PMC8489959  PubMed

Yoo S, Kim J, Lyu P, Hoang TV, Ma A, Trinh V, Dai W, Jiang L, Leavey P, Duncan L, Won JK, Park SH, Qian J, Brown SP, Blackshaw S., 2021, Control of neurogenic competence in mammalian hypothalamic tanycytes, Sci Adv., 7(22):eabg3777. doi: 10.1126/sciadv.abg3777, PMID: 34049878 PubMed

White CJ, Ellis JM, Wolfgang MJ, The role of ethanolamine phosphate phospholyase in regulation of astrocyte lipid homeostasis, 2021, J Biol Chem., 297(1):100830. doi: 10.1016/j.jbc.2021.100830, PMCID: PMC8233209. PubMed

Jeon SM, Chang D, Geske A, Ginty DD, Caterina MJ., 2021, Sex dependent reduction in mechanical allodynia in the sural-sparing nerve injury model in mice lacking Merkel cells., J Neurosci., :JN-RM-1668-20. doi: 10.1523/JNEUROSCI.1668-20.2021, PMID: 34031166  PubMed

Boleij A, Fathi P, Dalton W, Park B, Wu X, Huso D, Allen J, Besharati S, Anders RA, Housseau F, Mackenzie AE, Jenkins L, Milligan G, Wu S, Sears CL., 2021, G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis, Commun Biol., 4(1):585. doi: 10.1038/s42003-021-02014-3, PMCID: PMC8121840  PubMed

Yang X, McQuillen R, Lyu Z, Phillips-Mason P, De La Cruz A, McCausland JW, Liang H, DeMeester KE, Santiago CC, Grimes CL, de Boer P, Xiao J., 2021, A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW, Nat Microbiol., 6(5):584-593. doi: 10.1038/s41564-020-00853-0, PMCID: PMC8085133. PubMed

Kolar EA, Shi X, Clay EM, Moser AB, Lal B, Nirujogi RS, Pandey A, Bandaru VVR, Laterra J, Pei Z, Watkins PA., 2021, Very long-chain acyl-CoA synthetase 3 mediates onco-sphingolipid metabolism in malignant glioma, Med Res Arch., 9(5):2433. doi: 10.18103/mra.v9i5.2433. Epub 2021 May 25, PMCID: PMC8360346. PubMed

Peng D, Gleyzer R, Tai WH, Kumar P, Bian Q, Isaacs B, da Rocha EL, Cai S, DiNapoli K, Huang FW, Cahan P, 2021, Evaluating the transcriptional fidelity of cancer models, Genome Med., 13(1):73. doi: 10.1186/s13073-021-00888-w, PMCID: PMC8086312  PubMed

Whilden CM, Chevée M, An SY, Brown SP., 2021, The synaptic inputs and thalamic projections of two classes of layer 6 corticothalamic neurons in primary somatosensory cortex of the mouse, J Comp Neurol., doi: 10.1002/cne.25163, PMID: 33908623  PubMed

Türker F, Cook EK, Margolis SS., 2021, The proteasome and its role in the nervous system, Cell Chem Biol., 28(7):903-917. doi: 10.1016/j.chembiol.2021.04.003. PMCID: PMC8286317  PubMed

Shubin CB, Mayangsari R, Swett AD, Greider CW., 2021, Rif1 regulates telomere length through conserved HEAT repeats, Nucleic Acids Res., 49(7):3967-3980. doi: 10.1093/nar/gkab206, PMCID: PMC8053089  PubMed

Goldman DH, Livingston NM, Movsik J, Wu B, Green R, 2021, Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling, Mol Cell., 81(8):1830-1840.e8. doi: 10.1016/j.molcel.2021.01.029, PMCID: PMC8052310.  PubMed

Pokrass MJ, Regot S, 2021, 3D time-lapse microscopy paired with endpoint lineage analysis in mouse blastocysts, STAR Protoc., 2(2):100446. doi: 10.1016/j.xpro.2021.100446, PMCID: PMC8055709  PubMed

Poll BG, Xu J, Jun S, Sanchez J, Zaidman NA, He X, Lester L, Berkowitz DE, Paolocci N, Gao WD, Pluznick JL., 2021, Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility Along with Blood Pressure, J Pharmacol Exp Ther.,377(1):39-50. doi: 10.1124/jpet.120.000187, PMCID: PMC7985618  PubMed

Wang Y, Cottle WT, Wang H, Feng XA, Mallon J, Gavrilov M, Bailey S, Ha T., 2021, Genome oligopaint via local denaturation fluorescence in situ hybridization, Mol Cell., 81(7):1566-1577.e8. doi: 10.1016/j.molcel.2021.02.011, PMCID: PMC8026568  PubMed

Zaepfel BL, Zhang Z, Maulding K, Coyne AN, Cheng W, Hayes LR, Lloyd TE, Sun S, Rothstein JD., 2021, UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction, Cell Rep., 34(13):108925. doi: 10.1016/j.celrep.2021.108925. PMID: 33789100 PubMed

Johnston ML, Freel Meyers CL., 2021, Revealing Donor Substrate-Dependent Mechanistic Control on DXPS, an Enzyme in Bacterial Central Metabolism, Biochemistry, 60(12):929-939. doi: 10.1021/acs.biochem.1c00019. PMCID: PMC8015787  PubMed

Wang Y, Bae T, Thorpe J, Sherman MA, Jones AG, Cho S, Daily K, Dou Y, Ganz J, Galor A, Lobon I, Pattni R, Rosenbluh C, Tomasi S, Tomasini L, Yang X, Zhou B, Akbarian S, Ball LL, Bizzotto S, Emery SB, Doan R, Fasching L, Jang Y, Juan D, Lizano E, Luquette LJ, Moldovan JB, Narurkar R, Oetjens MT, Rodin RE, Sekar S, Shin JH, Soriano E, Straub RE, Zhou W, Chess A, Gleeson JG, Marquès-Bonet T, Park PJ, Peters MA, Pevsner J, Walsh CA, Weinberger DR; Brain Somatic Mosaicism Network, Vaccarino FM, Moran JV, Urban AE, Kidd JM, Mills RE, Abyzov A., 2021, Comprehensive identification of somatic nucleotide variants in human brain tissue, Genome Biol., 22(1):92. doi: 10.1186/s13059-021-02285-3. PMCID: PMC8006362  PubMed

Clark HR, McKenney C, Livingston NM, Gershman A, Sajjan S, Chan IS, Ewald AJ, Timp W, Wu B, Singh A, Regot S, 2021, Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level, Nat Commun., 12(1):1836. doi: 10.1038/s41467-021-22070-x, PMCID: PMC7988009  PubMed

Narkar A, Johnson BA, Bharne P, Zhu J, Padmanaban V, Biswas D, Fraser A, Iglesias PA, Ewald AJ, Li R., 2021, On the role of p53 in the cellular response to aneuploidy, Cell Rep., 34(12):108892. doi: 10.1016/j.celrep.2021.108892. PMID: 33761356. PubMed

Wong X, Cutler JA, Hoskins VE, Gordon M, Madugundu AK, Pandey A, Reddy KL., 2021, Mapping the micro-proteome of the nuclear lamina and lamina-associated domains, Life Sci Alliance, 4(5):e202000774. doi: 10.26508/lsa.202000774. PMCID: PMC8008952  PubMed

Yang W, Pang D, Chen M, Du C, Jia L, Wang L, He Y, Jiang W, Luo L, Yu Z, Mao M, Yuan Q, Tang P, Xia X, Cui Y, Jing B, Platero A, Liu Y, Wei Y, Worley PF, Xiao B., 2021, Rheb mediates neuronal-activity-induced mitochondrial energetics through mTORC1-independent PDH activation, Dev Cell., 56(6):811-825.e6. doi: 10.1016/j.devcel.2021.02.022. PMID: 33725483  PubMed

Gordon MR, Zhu J, Qu V, Li R., 2021, A case of convergent-gene interference in the budding yeast knockout library causing chromosome instability, G3 (Bethesda), 11(5):jkab084. doi: 10.1093/g3journal/jkab084. PMCID: PMC8104933.  PubMed

Xu Z, Green B, Benoit N, Sobel JD, Schatz MC, Wheelan S, Cormack BP., 2021, Cell wall protein variation, break-induced replication, and subtelomere dynamics in Candida glabrata, Mol Microbiol., doi: 10.1111/mmi.14707. Epub ahead of print. PMID: 33713372. PubMed

Martinez M, Renuse S, Kreimer S, O’Meally R, Natov P, Madugundu AK, Nirujogi RS, Tahir R, Cole R, Pandey A, Zachara NE., 2021, Quantitative Proteomics Reveals that the OGT Interactome is Remodeled in Response to Oxidative Stress, Mol Cell Proteomics., 100069. doi: 10.1016/j.mcpro.2021.100069. Epub ahead of print. PMID: 33716169 PubMed

Cadena AM, Ventura JD, Abbink P, Borducchi EN, Tuyishime H, Mercado NB, Walker-Sperling V, Siamatu M, Liu PT, Chandrashekar A, Nkolola JP, McMahan K, Kordana N, Hamza V, Bondzie EA, Fray E, Kumar M, Fischinger S, Shin SA, Lewis MG, Siliciano RF, Alter G, Barouch DH., 2021, Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques, Nat Commun., 12(1):1474. doi: 10.1038/s41467-021-21724-0. PMCID: PMC7935896. PubMed

Thorpe J, Frelin LP, McCann M, Pardo CA, Cohen BA, Comi AM, Pevsner J., 2021, Identification of a Mosaic Activating Mutation in GNA11 in Atypical Sturge-Weber Syndrome, J Invest Dermatol., 141(3):685-688. doi: 10.1016/j.jid.2020.03.978. PMCID: PMC8483769  PubMed

Maynard KR, Collado-Torres L, Weber LM, Uytingco C, Barry BK, Williams SR, Catallini JL 2nd, Tran MN, Besich Z, Tippani M, Chew J, Yin Y, Kleinman JE, Hyde TM, Rao N, Hicks SC, Martinowich K, Jaffe AE., 2021, Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex, Nat Neurosci., 24(3):425-436. doi: 10.1038/s41593-020-00787-0. Epub 2021 Feb 8. Erratum in: Nat Neurosci.; PMID: 33558695.  PubMed

Sam PN, Calzada E, Acoba MG, Zhao T, Watanabe Y, Nejatfard A, Trinidad JC, Shutt TE, Neal SE, Claypool SM., 2021, Impaired phosphatidylethanolamine metabolism activates a reversible stress response that detects and resolves mutant mitochondrial precursors, iScience, 24(3):102196. doi: 10.1016/j.isci.2021.102196. PMCID: PMC7921845. PubMed

Mahadevaraju, S., Fear, JM., Akeju, M., Galletta, BJ., Pinheiro, MMLS., Avelino, CC., Cabral-de-Mello, DC., Conlon, K., Dell’Orso, S., Demere, Z., Mansuria, K., Mendonça, CA., Palacios-Gimenez, OM., Ross, E., Savery, M., Yu, K., Smith, HE., Sartorelli, V., Yang, H., Rusan, NM., Vibranovski, MD., Matunis, E., Oliver, B., 2021, Dynamic sex chromosome expression in Drosophila male germ cells, Nat Commun., 12(1):892. doi: 10.1038/s41467-021-20897-y. PMCID: PMC7873209  PubMed

Workman, RE., Pammi, T., Nguyen, BTK., Graeff, LW., Smith, E., Sebald, SM., Stoltzfus, MJ., Euler, CW., Modell, JW., 2021, A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression, Cell, 184(3):675-688.e19. doi: 10.1016/j.cell.2020.12.017. PMID: 33421369  PubMed

Simonetti FR, Zhang H, Soroosh GP, Duan J, Rhodehouse K, Hill AL, Beg SA, McCormick K, Raymond HE, Nobles CL, Everett JK, Kwon KJ, White JA, Lai J, Margolick JB, Hoh R, Deeks SG, Bushman FD, Siliciano JD, Siliciano RF., 2021, Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo, J Clin Invest., 131(3):e145254. doi: 10.1172/JCI145254. PMCID: PMC7843227.  PubMed

Bowman CE, Arany Z, Wolfgang MJ., 2021, Regulation of maternal-fetal metabolic communication, Cell Mol Life Sci., 78(4):1455-1486. doi: 10.1007/s00018-020-03674-w. PMCID: PMC7904600  PubMed

Konopka JK, Task D, Afify A, Raji J, Deibel K, Maguire S, Lawrence R, Potter CJ., 2021, Olfaction in Anopheles mosquitoes, Chem Senses, 46:bjab021. doi: 10.1093/chemse/bjab021, PMCID: PMC8256107.  PubMed

Li, S., Raychaudhuri, S., Lee, SA., Brockmann, MM., Wang, J., Kusick, G., Prater, C., Syed, S., Falahati, H., Ramos, R., Bartol, TM., Hosy, E., Watanabe, S., 2021, Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses, Nat Commun., 12(1):677. doi: 10.1038/s41467-021-21004-x. PMCID: PMC7846561  PubMed

McCausland, JW., Yang, X., Squyres, GR., Lyu, Z., Bruce, KE., Lamanna, MM., Söderström, B., Garner, EC., Winkler, ME., Xiao, J., Liu, J., 2021, Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism, Nat Commun., 12(1):609. doi: 10.1038/s41467-020-20873-y. PMCID: PMC7840769  PubMed

Gershman A, Romer TG, Fan Y, Razaghi R, Smith WA, Timp W., 2021, De novo genome assembly of the tobacco hornworm moth (Manduca sexta), G3 (Bethesda). 11(1):jkaa047. doi: 10.1093/g3journal/jkaa047, PMCID: PMC8022704. PubMed

Phan TP, Maryniak AL, Boatwright CA, Lee J, Atkins A, Tijhuis A, Spierings DC, Bazzi H, Foijer F, Jordan PW, Stracker TH, Holland AJ., 2021, Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway, EMBO J., 40(1):e106118. doi: 10.15252/embj.2020106118, PMCID: PMC7780150.  PubMed

Tahir R, Renuse S, Udainiya S, Madugundu AK, Cutler JA, Nirujogi RS, Na CH, Xu Y, Wu X, Pandey A., 2021, Mutation-Specific and Common Phosphotyrosine Signatures of KRAS G12D and G13D Alleles, J Proteome Res., 20(1):670-683. doi: 10.1021/acs.jproteome.0c00587, PMID: 32986951  PubMed

Obregon-Perko V, Bricker KM, Mensah G, Uddin F, Kumar MR, Fray EJ, Siliciano RF, Schoof N, Horner A, Mavigner M, Liang S, Vanderford T, Sass J, Chan C, Berendam SJ, Bar KJ, Shaw GM, Silvestri G, Fouda GG, Permar SR, Chahroudi A., 2020, Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4⁺ T Cells, J Virol., 95(2):e01669-20. doi: 10.1128/JVI.01669-20. PMCID: PMC7944446 PubMed

Watanabe, S., Davis, MW., Kusick, GF., Iwasa, J., Jorgensen, EM., 2020, SynapsEM: Computer-Assisted Synapse Morphometry, Front Synaptic Neurosci, 12:584549. doi: 10.3389/fnsyn.2020.584549. PMCID: PMC7775558  PubMed

Sarver DC, Stewart AN, Rodriguez S, Little HC, Aja S, Wong GW., 2020, “Loss of CTRP4 alters adiposity and food intake behaviors in obese mice.” Am J Physiol Endocrinol Metab. 2020 Oct 5. doi: 10.1152/ajpendo.00448.2020. Epub ahead of print. PMID: 33017221. PubMed

Patterson L, Allen J, Posey I, Shaw JJP, Costa-Pinheiro P, Walker SJ, Gademsey A, Wu X, Wu S, Zachos NC, Fox TE, Sears CL, Kester M., 2020, Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin-induced colon epithelial cell signaling, FASEB J., 34(12):15922-15945. doi: 10.1096/fj.202001669R, PMID: 33047400  PubMed

DiNapoli, KT., Robinson, DN., Iglesias, PA., Tools for computational analysis of moving boundary problems in cellular mechanobiology, Wiley Interdiscip Rev Syst Biol Med, e1514. doi: 10.1002/wsbm.1514. PMID: 33305503  PubMed

Osei-Owusu, IA., Norris, AL., Joynt, AT., Thorpe, J., Cho, S., Tierney, E., Schmidt, J., Hagopian, L., Harris, J., Pevsner, J., 2020, Characterization of an unbalanced translocation causing 3q28qter duplication and 10q26.2qter deletion in a patient with global developmental delay and self-injury, Cold Spring Harb Mol Case Stud., 6(6):a005884. doi: 10.1101/mcs.a005884. PMCID: PMC7784495  PubMed

Chai, Z., Silverman, D., Li, G., Williams, D., Raviola, E., Yau, KW., 2020, Light-dependent photoreceptor orientation in mouse retina, Sci Adv., 6(51):eabe2782. doi: 10.1126/sciadv.abe2782. PMCID: PMC7744070 PubMed

Mihaljević L, Urban S., 2020, Decoding the Functional Evolution of an Intramembrane Protease Superfamily by Statistical Coupling Analysis, Structure, 28(12):1329-1336.e4. doi: 10.1016/j.str.2020.07.015. PMCID: PMC7710553  PubMed

Lee, I., Razaghi, R., Gilpatrick, T., Molnar, M., Gershman, A., Sadowski, N., Sedlazeck, FJ., Hansen, KD., Simpson, JT., Timp, W., 2020, Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing, Nat Methods, 17(12):1191-1199. doi: 10.1038/s41592-020-01000-7. PMCID: PMC7704922 PubMed

Thorpe J, Osei-Owusu IA, Avigdor BE, Tupler R, Pevsner J., 2020, Mosaicism in Human Health and Disease, Annu Rev Genet., 54:487-510. doi: 10.1146/annurev-genet-041720-093403. Epub 2020 Sep 11. PMID: 32916079.  PubMed

Barrows JM, Goley ED, 2021, FtsZ dynamics in bacterial division: What, how, and why?, Curr Opin Cell Biol., 2021 Feb;68:163-172. doi: 10.1016/j.ceb.2020.10.013. PMCID: PMC7925355.  PubMed

Gonzalez-Magaldi M, McCabe JM, Cartwright HN, Sun N, Leahy DJ., 2020, Conserved roles for receptor tyrosine kinase extracellular regions in regulating receptor and pathway activity, Biochem J., 477(21):4207-4220. doi: 10.1042/BCJ20200702. PMID: 33043983  PubMed

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Rodriguez, S., Lei, X., Petersen, PS., Tan, SY., Little, HC., Wong, GW., 2016, “Loss of CTRP1 disrupts glucose and lipid homeostasis,” Am J Physiol Endocrinol Metab. 23:ajpendo.00087.2016. PMID: 27555298 PubMed

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Yuan, G., Peng, YJ., Khan, SA., Nanduri, J., Singh, A., Vasavda, C., Semenza, GL., Kumar, GK., Snyder, SH. and Prabhakar, NR., 2016, “H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea,” Sci Signal. 9(441):ra80. PMID: 27531649 PubMed

Laskey, SB., Pohlmeyer, CW., Bruner, KM. and Siliciano, RF., 2016, “Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality,”  PLoS Pathog. 12(8):e1005689. PMCID:PMC4975415 PubMed

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Goldschmidt, HL., Tu-Sekine, B., Volk, L., Anggono, V., Huganir, RL. and Raben, DM., 2016,  “DGKθ Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses,” Cell Rep. 14(2):200-7. PubMed

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Mitchell, CJ., Kim, MS., Zhong, J., Nirujogi, RS., Bose, AK., and Pandey, A., 2016, “Unbiased identification of substrates of protein tyrosine phosphatase ptp-3 in C. elegans,” Mol Oncol.  pii: S1574-7891(16)30010-2.​ PubMed​

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Lei, X., Rodriguez, S., Petersen, PS., Seldin, MM., Bowman, CE., Wolfgang, MJ., and Wong, GW., 2016, “Loss of CTRP5 improves insulin action and hepatic steatosis,” Am J Physiol Endocrinol Metab. ajpendo.00010.2016. PubMed

Bowman, CE., Zhao, L., Hartung, T., and Wolfgang, MJ., 2016, “Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series,” Mol Cell Biol. 36(15):2089-104. PMCID: PMC4946427 PubMed 

Lin, X., Steinberg, S., Kandasamy, SK., Afzal, J., Mbiyangandu, B., Liao, SE., Guan, Y., Corona-Villalobos, CP., Matkovich, SJ.,  Epstein, N., Tripodi, D., Huo, Z., Cutting, G., Abraham, TP., Fukunaga, R., and Abraham, MR., 2016, “Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis,” PLoS One. 11(5):e0156065. eCollection 2016.​  PubMed

Pokorná, L., Čermáková, P., Horváth, A., Baile, MG., Claypool, SM., Griač, P., Malínský, J. and Balážová, M., 2016, “Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and function,” Biochim Biophys Acta. 1857(1):34-45. PMCID: PMC4690203  PubMed

Mitchell, CJ., Kim, MS., Na, CH., and Pandey, A., 2016, ” PyQuant: a versatile framework for analysis of quantitative mass spectrometry data,” Mol Cell Proteomics. pii: mcp.O115.056879  15(8):2829-38. PMCID: PMC4974355  PubMed​

Lee, J., Choi, J., Wong, GW., and Wolfgang, MJ., 2016, “Neurometabolic roles of ApoE and Ldl-R in mouse brain,” J Bioenerg Biomembr. ​48(1):13-21. PMCID: PMC4733629  PubMed

Maruotti, J., Sripathi, SR., Bharti, K., Fuller, J., Wahlin, KJ., Ranganathan, V., Sluch, VM., Berlinicke, CA., Davis, J., Kim, C., Zhao, L., Wan, J., Qian, J., Corneo, B., Temple, S., Dubey, R., Olenyuk, BZ., Bhutto, I., Lutty, GA., and Zack, DJ., 2015, “Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells,” Proc Natl Acad Sci U S A. 112(35):10950-5.​ PMCID: PMC4568212  PubMed

Lin, Q., Jia, B., Mitchell, LA., Luo, J., Yang, K., Zeller, KI., Zhang, W., Xu, Z., Stracquadanio, G., Bader, JS., Boeke, JD., and Yuan, YJ., 2015, “RADOM, an efficient in vivo method for assembling designed DNA fragments up to 10 kb long in Saccharomyces cerevisiae,” ACS Synth Biol. 4(3):213-20.​ PubMed

Clister, T., Mehta, S. and Zhang, J., 2015, “Single-cell Analysis of G-protein Signal Transduction,” J Biol Chem, 290(11):6681-8. PMCID: PMC4358091 PubMed

Greenspan, LJ., de Cuevas, M. and Matunis, E., 2015, “Genetics of Gonadal Stem Cell Renewal,” Annu Rev Cell Dev Biol,31:291-315  PMCID: PMC4659427 PubMed

Garcia-Gonzalo FR*, Phua SC*, Roberson EC, Garcia III G, Abedin M, Schurmans S, Inoue T, Reiter JF. 2015. Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Developmental Cell. 34: 400-409. (*co-first authors) PMCID: PMC4557815 PubMed

Phua, SC., Lin, YC. and Inoue, T., 2015, “An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli,” Cell Calcium, 58: 415-422, Review. PMCID: PMC4564334 [Available on 2016-10-01] PubMed

Koutmou, KS., Schuller, AP., Brunelle, JL., Radhakrishnan, A., Djuranovic, S. and Green, R., 2015, “Ribosomes slide on lysine-encoding homopolymeric A stretches,” Elife, 4: e05534. PMCID: PMC4363877 PubMed

Goodrich, AC. and Frueh, DP., 2015, “A Nuclear Magnetic Resonance Method for Probing Molecular Influences of Substrate Loading in Nonribosomal Peptide Synthetase Carrier Proteins. Biochemistry, 54, 1154-6.  PMCID: PMC4378656 PubMed

Lu, YW. and Claypool, SM., 2015, “Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes,” Front Genet. 2015 Feb 3;6:3 PMCID: PMC4315098

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Kowalinski, E., Schuller, A., Green, R. and Conti, E., 2015, “Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases,” Structure, 23(7):1336-43 PMCID: PMC4509514  PubMed

Sluch, VM., Davis, CH., Ranganathan, V., Kerr, JM., Krick, K., Martin, R., Berlinicke, CA., Marsh-Armstrong, N., Diamond, JS., Mao, HQ. and Zack, DJ., 2015, “Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line,” Sci Rep. 5:16595. PMCID: PMC4643248 PubMed

Cheng, YL. and Andrew, DJ., 2015, “Extracellular Mipp1 Activity Confers Migratory Advantage to Epithelial Cells during Collective Migration,” Cell Rep. 13(10):2174-88. PMCID: PMC4776642. PubMed

Goodrich, AC., Harden, BJ. and Frueh, DP., 2015, “Solution Structure of a Nonribosomal Peptide Synthetase Carrier Protein Loaded with Its Substrate Reveals Transient, Well-Defined Contacts,” J Am Chem Soc. PMID: 26334259​ PubMed

Sun, G. j, Zhou, Y., Ito, S., Bonaguidi, M. a, O’Brien, G. s, Kawasaki, N., Modak, N., Zhu, Y., Ming, G.-L., Song, H., “Latent tri-lineage potential of adult neural stem cells in the hippocampus revealed by Nf1 inactivation”, Nature Neuroscience, 2015 Dec;18(12):1722-4. PMID: 26523645 PubMed

Ward, MD. and Leahy, DJ., 2015, “Kinase activator-receiver preference in ErbB heterodimers is determined by intracellular regions and is not coupled to extracellular asymmetry,” J Biol Chem. 290(3):1570-9. PMCID: PMC4340403 PubMed

Deng, K., Pertea, M., Rongvaux, A., Wang, L., Durand, CM., Ghiaur, G., Lai, J., McHugh, HL., Hao, H., Zhang, H., Margolick, JB., Gurer, C., Murphy, AJ., Valenzuela, DM., Yancopoulos, GD., Deeks, SG., Strowig, T., Kumar, P., Siliciano, JD., Salzberg, SL., Flavell, RA., Shan, L. and Siliciano, RF, 2015, “Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations,” Nature.15;517(7534):381-5. PMCID: PMC4406054  PubMed

Multhaup, ML., Seldin, MM., Jaffe, AE., Lei, X., Kirchner, H., Mondal, P., Li, Y., Rodriguez, V., Drong, A., Hussain, M., Lindgren, C., McCarthy, M., Näslund, E., Zierath, JR., Wong, GW. and Feinberg, AP., 2015, “Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes,” Cell Metab. 21(1):138-49. PMCID: PMC4340475  PubMed

Dancy, BM. and Cole, PA., 2015, “Protein Lysine Acetylation by p300/CBP,” Chem Rev, 115(6):2419-52. PMCID: PMC4378506 PubMed

Goodrich, AC. and Frueh, DP., 2015, “A Nuclear Magnetic Resonance Method for Probing Molecular Influences of Substrate Loading in Nonribosomal Peptide Synthetase Carrier Proteins. Biochemistry, 54, 1154-6.  PMCID: PMC4378656 PubMed

Harr, JC.*, Luperchio, TR.*, Wong, X.*, Cohen, E*., Wheelan, SJ. and Reddy, KL., 2015, “Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins,” J Cell Biol. 208(1):33-52. PMCID: PMC4284222 *equal contribution.​ PubMed​

Surcel, A., Ng, WP., West-Foyle, H., Zhu, Q., Ren, Y., Avery, LB., Krenc, AK., Meyers, DJ., Rock, RS., Anders, RA., Freel, Meyers, CL. and Robinson, DN., 2015, “Pharmacological activation of myosin II paralogs to correct cell mechanics defects,” Proc Natl Acad Sci USA, 112(5):1428-33.  PMCID: PMC4321244 PubMed​

Clister, T., Mehta, S. and Zhang, J., 2015, “Single-cell Analysis of G-protein Signal Transduction,” J Biol Chem, 290(11):6681-8. PMCID: PMC4358091 PubMed

Koutmou, K.S., Schuller, A.P., Brunelle, J.L., Radhakrishnan, A., Djuranovic, S. & Green, R. Ribosomes slide on lysine-encoding homopolymeric A stretches. eLife, e05534 (2015). . PMCID: PMC4363877 PubMed​

Lu, YW. and Claypool, SM., 2015, “Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes,” Front Genet. 2015 Feb 3;6:3 PMCID: PMC4315098  PubMed​

Lei, X.*, Li, Q., Rodriguez, S.*, Tan, SY.*, Seldin, MM.*, McLenithan, JC., Jia, W. and Wong, GW., 2015, “Thromboxane synthase deficiency improves insulin action and attenuates adipose tissue fibrosis,” Am J Physiol Endocrinol Metab. 308(9):E792-804 *equal contribution PubMed

Cox, E., Uzoma, I., Guzzo, C., Jeong, JS., Matunis, M., Blackshaw, S. and Zhu, H., 2015, “Identification of SUMO E3 Ligase-Specific Substrates Using the HuProt Human Proteome Microarray,” Methods Mol Biol. 1295:455-63. PMCID: unknown PubMed

Zhou, X., Clister, TL., Lowry, PR., Seldin, MM., Wong, GW. and Zhang, J., 2015, “Dynamic Visualization of mTORC1 Activity in Living Cells,” Cell Rep. pii: S2211-1247(15)00177-1. PMCID: PMC4567530  PubMed

Eginton C, Cressman WJ, Bachas S, Wade H, Beckett D. Allosteric Coupling via Distant Disorder-to-Order Transitions. J Mol Biol. 2015 Apr 24;427(8):1695-1704. doi: 10.1016/j.jmb.2015.02.021. Epub 2015 Mar 4. PubMed

Deng, H., Wang, W., Yu, J., Zheng, Y., Qing, Y., and Pan, D., 2015, “Spectrin regulates Hippo signaling by modulating cortical actomyosin activity,”  ELife, 4:e06567.  PMCID: PMC4412106  PubMed

Yoo, SW., Motari, MG., Susuki, K., Prendergast, J., Mountney, A., Hurtado, A. and Schnaar, RL., 2015 “Sialylation regulates brain structure and function,” FASEB J. 29(7):3040-53. PMCID: PMC4478807 PubMed​

Metcalf, Pate, KA., Pohlmeyer, CW., Walker-Sperling, VE., Foote, JB., Najarro, KM., Cryer, CG., Salgado, M., Gama, L., Engle, EL., Shirk, EN., Queen, SE., Chioma, S., Vermillion, MS., Bullock, B., Li, M., Lyons, CE., Adams, RJ., Zink, MC., Clements, JE., Mankowski, JL. and Blankson, JN., 2015, “A murine viral outgrowth assay to detect residual HIV-1 in patients with undetectable viral loads,” J Infect Dis. 212:1387-1396. PMCID: PMC4601916 ​ PubMed

Onguka, O., Calzada, E., Ogunbona, OB. and Claypool, SM., 2015, “Phosphatidylserine Decarboxylase 1 Autocatalysis and Function Does Not Require a Mitochondrial-specific Factor,” J Biol Chem, 290: 12744-52  PMCID: PMC4432291  PubMed​

Li, Z., He, SQ., Tseng, PY., Xu, Q., Tiwari, V., Yang, F., Shu, B., Zhang, T., Tang, Z., Raja, SN., Wang, Y., Dong, X. and Guan, Y., 2015, “The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms,” Neuroscience, 300:393-403. PMCID: PMC4485588  PubMed​

Zhang, W., Wu, J., Ward, MD., Yang, S., Chuang, YA., Xiao, M., Li, R., Leahy, DJ. and Worley, PF., 2015, “Structural basis of arc binding to synaptic proteins: implications for cognitive disease.” Neuron. 22;86(2):490-500. PMCID: PMC4409568 PubMed

Kurbanov, F., Kim, Y., Latanich, R., Chaudhari, P., El-Diwany, R., Knabel, M., Kandathil, AJ., Cameron, A., Cox, A., Jang, YY., Thomas, DL. and Balagopal, A., 2015, “IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes,” Antivir Ther. doi: 10.3851/IMP2974. [Epub ahead of print]  PMCID: unknownPubMed

Hasan, S., Hétié, P amd Matunis, EL., 2015, “Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1,” Dev Biol, 404(1):27-39 PMCID: PMC4469572 PubMed

Westerbeck, JW. and Machamer, CE., 2015, “A Coronavirus E Protein is Present in Two Distinct Pools with Different Effects on Assembly and the Secretory Pathway,” J Virol., 89:18.  PMCID: PMC4542375  PubMed

Zhou, Y., Williams, J., Smallwood, PM. and Nathans, J., 2015, “Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina,” PLoS One. 10(12):e0143650.​ ​ PubMed

Lim, C., Gandhi, S., Biniossek, ML., Feng, L., Schilling, O., Urban, S., and Chen, X., 2015, “An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation,” Cell Rep. 13(2):315-25. PMCID: PMC4607668 PubMed

Subramanian, M., Timmerman, CK., Schwartz, J.L., Pham, DL. and Meffert, MK., 2015, “Characterizing autism spectrum disorders by key biochemical pathways,” Front Neurosci. 9:313.  Review. PMCID: PMC4586332 . PubMed

Lambrus, BG., Uetake, Y., Clutario, KM., Daggubati, V., Snyder, M., Sluder, G. and Holland, AJ., 2015, “p53 protects against genome instability following centriole duplication failure,” J Cell Biol., 210(1):63-77. PMCID: PMC4494000  PubMed

Hobbs, RP., DePianto, DJ., Jacob, JT., Han, MC., Chung, BM., Batazzi, AS., Poll, BG., Guo, Y., Han, J., Ong, S., Zheng, W., Taube, JM., Čiháková, D., Wan, F. and Coulombe, PA. 2015, “Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes,” Nat Genet. 47(8):933-8. PMCID: PMC4520766 ​PubMed​

Moore,CD.*, Ajala, OZ.* and Zhu, H., 2015, “Applications in high-content functional protein microarrays,” Curr Opin Chem Biol. 30:21-27.  Review. *equal contribution PubMed

Echeverria, I., Liu, Y., Gabelli, SB., and Amzel, LM., 2015, “Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α,” FEBS J. 282(18):3528-42.​ PMCID: PMC4573839 PubMed

Margolis, SS., Sell, GL., Zbinden, MA., and Bird, LM., 2015, “Angelman Syndrome,” Neurotherapeutics. 12(3):641-50.​ ​ PubMed

Ellis, JM., Bowman, CE. and Wolfgang, MJ., 2015, “Metabolic and tissue-specific regulation of acyl-CoA metabolism,” PLoS One. 10(3):e0116587.​ ​ PubMed

Yuan, G.*, Vasavda, C.*, Peng, YJ.*, Makarenko, VV.*, Raghuraman, G., Nanduri, J., Gadalla, MM., Semenza, GL., Kumar, GK., Snyder, SH. and Prabhakar, NR., 2015, “Protein kinase G-regulated production of H2S governs oxygen sensing,” Sci Signal. 8(373):ra37. *equal contribution  PubMed​

Mohammad, F., Woolstenhulme, CJ., Green, R., and Buskirk, AR., 2015, “Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling,” Cell Rep. pii: S2211-1247(15)01529-6.​  PubMed

Metcalf Pate, KA., Pohlmeyer, CW., Walker-Sperling, VE., Foote, JB., Najarro, KM., Cryer, CG., Salgado, M., Gama, L., Engle, EL., Shirk, EN., Queen, SE., Chioma, S., Vermillion, MS., Bullock, B., Li, M., Lyons, CE., Adams, RJ., Zink, MC., Clements, JE., Mankowski, JL., and Blankson, JN., 2015, “A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads,” J Infect Dis. 212(9):1387-96. PubMed

de la Peña, AH., Suarez, A., Duong-Ly, KC., Schoeffield, AJ., Pizarro-Dupuy, MA., Zarr, M., Pineiro, SA., Amzel, LM. and Gabelli, SB., 2015, “Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus,” PLoS One, PMID: 26524597 PubMed

Baras, AS., Mitchell, CJ., Myers, JR., Gupta, S., Weng, LC., Ashton, JM., Cornish, TC., Pandey, A. and  Halushka, MK., 2015, “miRge – A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy,” PLoS One. PMID: 26571139  PubMed

Phua, SC., Lin, YC. and Inoue, T., 2015, “An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli,” Cell Calcium. 58(4):415-22. Review. PMID: 25828566 PubMed​

Lim, C., Gandhi, S., Biniossek, ML., Feng, L., Schilling, O., Urban, S., Chen, X., 2015, An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation. Cell Rep. 13(2):315-25. PMID: 26440886  PubMed

Sundararajan, K.*, Miguel, A., Desmarais, SM., Meier, EL*., Casey, Huang, K. and Goley, ED.*, 2015, “The bacterial tubulin FtsZ requires its intrinsically disordered linker to direct robust cell wall construction,” Nat Commun. 6:7281. PMCID: PMC4532373 *equal contribution​ PubMed

Kurbanov, F., Kim, Y., Latanich, R., Chaudhari, P., El-Diwany, R., Knabel, M., Kandathil, AJ., Cameron, A., Cox, A., Jang, YY., Thomas, DL. and Balagopal, A., 2015, “IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes,” Antivir Ther. doi: 10.3851/IMP2974. [Epub ahead of print]  PMCID: unknown PubMed

Greenspan, LJ., de Cuevas, M. and Matunis, E., 2015, “Genetics of gonadal stem cell renewal,” Annu Rev Cell Dev Biol. 31:291-315. PMID: 26355592 PubMed​

Lee, CF., Lo, YC., Cheng, CH., Furtmüller, GJ., Oh, B., Andrade-Oliveira, V., Thomas, AG., Bowman, CE., Slusher, BS., Wolfgang, MJ., Brandacher, G., Powell, JD., 2015, “Preventing Allograft Rejection by Targeting Immune Metabolism,” Cell Rep. 13(4):760-70. PMID: 26489460 PubMed

Mitchell, CJ., Getnet, D., Kim, MS., Manda, SS., Kumar, P., Huang, TC., Pinto, SM., Nirujogi, RS., Iwasaki, M., Shaw, PG., Wu, X., Zhong, J., Chaerkady, R., Marimuthu, A., Muthusamy, B., Sahasrabuddhe, NA., Raju, R., Bowman, C., Danilova, L., Cutler, J., Kelkar, DS., Drake, CG., Prasad, TS., Marchionni, L., Murakami, PN., Scott, AF., Shi, L., Thierry-Mieg, J., Thierry-Mieg, D., Irizarry, R., Cope, L., Ishihama, Y., Wang, C., Gowda, H. and Pandey, A., 2015, “A multi-omic analysis of human naïve CD4+ T cells,” BMC Syst Biol. 9:75. PMID: 26542228 PubMed

Goodrich, A.C., Nichols, S.R., and Frueh, D.P, 2014, “Resonance Assignments and Structure Determination of Large and Challenging Proteins,” Encyclopedia of Magnetic Resonance. 3. 

Zhang, H., Zou, B., Du, F., Xu, K. and Li, M., 2014, “Reporting Sodium Channel Activity using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5,” Mol Pharmacol.87(2):207-17  PMCID: PMC4293450 PubMed

Van den Elzen, A.M.G., Schuller, A., Green, R. and Séraphin, B., 2014, “Dom34-Hbs1 mediated dissociation of inactive 80S ribosomes promotes restart of translation after stress.,” EMBO J. 33, 265-276 (2014). PMCID: PMC3989619 ​PubMed

Davis, C.-H.O., Kim, K.-Y., Bushong, E. a, Mills, E. a, Boassa, D., Shih, T., Kinebuchi, M., Phan, S., Zhou, Y., Bihlmeyer, N. a, Nguyen, J.V., Jin, Y., Ellisman, M.H., Marsh-Armstrong, N., “Transcellular degradation of axonal mitochondria”, Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9633-8. PMID: 24979790 PubMed

Wang, JT. and Seydoux, G., 2014, “P granules,” Curr Biol. 24(14):R637-8. PubMed

Schaughency, P., Merran, J., and Corden, JL., 2014, “Genome-wide mapping of yeast RNA polymerase II termination,” PLoS Genet. 10(10):e1004632.​ PubMed

Bruner, JK., Zou, B., Zhang, H., Zhang, Y., Schmidt, K. and Li, M., 2014, “Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel,” Eur J Pharmacol. pii: S0014-2999(14)00463-4. PubMed

Clayton, AM., Dong, Y. and Dimopoulos, G., 2014, “The Anopheles innate immune system in the defense against malaria infection,” J Innate Immun. 6(2):169-81. PMCID: PMC3939431 PubMed

Baile, MG., Lu, YW. and Claypool, SM., 2014, “The topology and regulation of cardiolipin biosynthesis and remodeling in yeast,” Chem Phys Lipids, 179:25-31. PMCID: PMC3947685   PubMed

Wang, Y., Wang, JT., Rasoloson, D., Stitzel, ML., O’Connell, KF., Smith, HE. and Seydoux, G., 2014, “Identification of Suppressors of mbk-2/DYRK by Whole-Genome Sequencing,” G3 (Bethesda), 4(2):231-41.  PMCID: PMC3931558  PubMed

Hétié, P., de Cuevas, M. and Matunis, E., 2014, “Conversion of quiescent niche cells to somatic stem cells causes ectopic niche formation in the Drosophila testis,” Cell Rep. 7(3):715-21. PMCID: PMC4080611​ PubMed ​

Shamir, ER. and Ewald, AJ., 2014, “Three-dimensional organotypic culture: experimental models of mammalian biology and disease,” Nat Rev Mol Cell Biol. 15(10):647-64. PMCID: PMC4352326 PubMed

Rodriguez, S., Ellis, JM. and Wolfgang, MJ., 2014, “Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle,” BMC Biochem. 15:20.  PMCID: PMC4236586 ​PubMed​

Herb, BR., 2014, “Epigenetics as an answer to Darwin’s “special difficulty”,” Front Genet. 5:321. PMCID: PMC4162389 PubMed

Chen, BC., Legant, WR., Wang, K., Shao, L., Milkie, DE., Davidson, MW., Janetopoulos, C., Wu, XS., Hammer, JA. 3rd, Liu, Z., English, BP., Mimori-Kiyosue, Y., Romero, DP., Ritter, AT., Lippincott-Schwartz, J., Fritz-Laylin, L., Mullins, RD., Mitchell, DM., Bembenek, JN., Reymann, AC., Böhme, R., Grill, SW., Wang, JT., Seydoux, G., Tulu, US., Kiehart, DP. and Betzig, E., 2014, “Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution,” Science. 346(6208):1257998. PMCID: PMC4336192 PubMed​

Hua, ZL., Jeon, S., Caterina, MJ. and Nathans, J., 2014, “Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system,” Proc Natl Acad Sci U S A. 111(29):E3005-14.  PMCID: PMC4115534​ PubMed

Ren, Y., West-Foyle, H., Surcel, A., Miller, C. and Robinson, DN., 2014, “Genetic suppression of a phosphomimic myosin II identifies system-level factors that promote myosin II cleavage furrow accumulation,” Mol Biol Cell. 25(25):4150-65.  PMCID: PMC4263456  PubMed

Salgado, M., Gandhi, S., Buckheit, RW., Berkenblit, GV. and Blankson, JN., 2014, “Evolution of an attenuated HIV-1 isolate in an elite suppressor,” AIDS Res Hum Retroviruses. 30(3):284-8. Epub 2013 Nov 13. PubMed

Cox, PM. and Bumpus, NN., 2014, “Structure-Activity Studies Reveal the Oxazinone Ring Is a Determinant of Cytochrome P450 2B6 Activity Toward Efavirenz,” ACS Med Chem Lett. 5(10):1156-1161. PMCID: PMC4191608 PubMed​

Levine, MS. and Holland, AJ., 2014, “Polo-like kinase 4 shapes up,” Structure, 22(8):1071-3.  PubMed

Kalia, J., Milescu, M., Salvatierra, J., Wagner, J., Klint, JK., King, GF., Olivera, BM. and Bosmans, F., 2014, “From Foe to Friend: Using Animal Toxins to Investigate Ion Channel Function,” J Mol Biol. 427(1):158-75, Review. PMCID: PMC4277912 PubMed

Salvatierra, J., Lee, DA., Zibetti, C., Duran-Moreno, M., Yoo, S., Newman, EA., Wang, H., Bedont, JL., de Melo, J., Miranda-Angulo, AL., Gil-Perotin, S., Garcia-Verdugo, JM. and Blackshaw, S., 2014, “The LIM Homeodomain Factor Lhx2 Is Required for Hypothalamic Tanycyte Specification and Differentiation,” J Neurosci. 34(50):16809-20. PMCID: PMC4261103 PubMed​

Bende, NS., Dziemborowicz, S., Mobli, M., Herzig, V., Gilchrist, J., Wagner, J., Nicholson, GM., King, GF. and Bosmans, F., 2014, “A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a,” Nat Commun. 5:4350. PMCID: PMC4115291 PubMed

Stine, RR., Greenspan, LJ., Ramachandran, KV. and Matunis, EL., 2014, “Coordinate Regulation of Stem Cell Competition by Slit-Robo and JAK-STAT Signaling in the Drosophila Testis,” PLoS Genet. 10(11):e1004713. PMCID: PMC4222695  PubMed

Cleveland, TE 4th., McCabe, JM. and Leahy, DJ., 2014, “Detergent-solubilized Patched purified from Sf9 cells fails to interact strongly with cognate Hedgehog or Ihog homologs,” Protein Expr Purif, 104C, 92-102. PMCID: PMC4380871 PubMed

McCabe, JM. and Leahy, DJ., 2014, “Smoothened Goes Molecular: New Pieces in the Hedgehog Signaling Puzzle.” J Biol Chem, 6: 3500-7 PMCID: PMC4319017 PubMed​

Kelkar, DS., Provost, E., Chaerkady, R., Muthusamy, B., Manda, SS., Subbannayya, T., Selvan, LD., Wang, CH., Datta, KK., Woo, S., Dwivedi, SB., Renuse, S., Getnet, D., Huang, TC., Kim, MS.,, Pinto, SM., Mitchell, CJ., Madugundu, AK., Kumar, P., Sharma, J., Advani, J., Dey, G., Balakrishnan, L., Syed, N., Nanjappa, V., Subbannayya, Y., Goel, R., Keshava Prasad, TS., Bafna, V., Sirdeshmukh, R., Gowda, H., Wang, C., Leach, SD. and Pandey, A., 2014, “Annotation of the Zebrafish Genome through an Integrated Transcriptomic and Proteomic Analysis,” Mol Cell Proteomics. 13(11):3184-98. PMCID: PMC4223501 PubMed

Qing, Y., Yin, F., Wang, W., Zheng, Y., Guo, P., Schozer, F., Deng, H., and Pan, D., 2014, “The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6,” Elife, 3.  PMCID: PMC4118621   PubMed

Mehta, S., Aye-Han, NN., Ganesan, A., Oldach, L., Gorshkov, K. and Zhang, J., 2014, “Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin,” Elife. 3:e03765. PMCID: PMC4141273 PubMed

Berk, JM., Simon, DN., Jenkins-Houk, CR., Westerbeck, JW., Grønning-Wang, LM., Carlson, CR. and Wilson, KL., 2014, “The molecular basis of emerin-emerin and emerin-BAF interactions,” J Cell Sci. 127(Pt 18):3956-69. PMCID: PMC4163644 PubMed

Zhou, Y. and Nathans, J., 2014, “Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling,” Dev Cell. 31(2):248-56. PMCID: PMC4223636  PubMed

Rattner, A., Wang, Y., Zhou, Y., Williams, J. and Nathans, JH., 2014, “The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling,” Invest Ophthalmol Vis Sci. 55(12):8614-25. PMCID: PMC4280883  PubMed

Wang, J. T., Smith, J., Chen, B.-C., Schmidt, H., Rasoloson, D., Paix, A., Lambrus, BG., Calidas, D., Betzig, E., and Seydoux, G., 2014, “Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically-disordered proteins in C. elegans,” eLife, 3: e04591. PMCID: PMC4296509 PubMed

Heydarian, M., Luperchio, TR., Cutler, J., Mitchell, CJ., Kim, M., Pandey, A., Sollner-Webb, B. and Reddy, K., 2014, “Prediction of Gene Activity in Early B Cell Development Based on an Integrative Multi-Omics Analysis,” J Proteomics Bioinform. 7. pii: 1000302. PMCID: PMC4276347 PubMed

Tu-Sekine, B., Goldschmidt, H. and Raben, DM., 2014, “Diacylglycerol, phosphatidic acid, and their metabolic enzymes in synaptic vesicle recycling,” Adv Biol Regul, 57:147-52. PubMed

Lu, C., Ward, A., Bettridge, J., Liu, Y. and Desiderio, S., 2014, “An Autoregulatory Mechanism Imposes Allosteric Control on the V(D)J Recombinase by Histone H3 Methylation,” Cell Rep.10(1):29-38 PMCID: PMC4308961 PubMed

Freed, D., Stevens, EL. and Pevsner, J., 2014, “Somatic mosaicism in the human genome,” Genes (Basel). 5(4):1064-94. Review. PMCID: PMC4276927 PubMed

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Suarez, A., Ueno, T., Huebner, R., McCaffery, JM. and Inoue, T., 2014, “Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells,” Sci Rep. 4:4693.   PubMed

Cross, BM., Breitwieser, GE., Reinhardt, TA. and Rao, R., 2014, “Cellular calcium dynamics in lactation and breast cancer: from physiology to pathology,” Am J Physiol Cell Physiol. 306(6):C515-26. PMCID: PMC3948975 PubMed​

Wong, X., Luperchio, TR. and Reddy, KL., 2014, “NET gains and losses: the role of changing nuclear envelope proteomes in genome regulation,” Curr Opin Cell Biol. 28C:105-120.  Review.​ PubMed

Colis, L., Peltonen, K., Sirajuddin, P., Liu, H., Sanders, S., Ernst, G., Barrow, JC. and Laiho, M., 2014, “DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response,” Oncotarget, 5(12):4361-4369. PMCID: PMC4147329 PubMed

Davis, CH., Kim, KY., Bushong, EA., Mills, EA., Boassa, D., Shih, T., Kinebuchi, M., Phan, S., Zhou, Y., Bihlmeyer, NA., Nguyen, JV., Jin, Y., Ellisman, MH. and Marsh-Armstrong, N., 2014, “Transcellular degradation of axonal mitochondria,” Proc Natl Acad Sci U S A. 111(26):9633-8.  PMCID: PMC4084443 PubMed

Guzzo, CM., Ringel, A., Cox, E., Uzoma, I., Zhu, H., Blackshaw, S., Wolberger, C. and Matunis, MJ., 2014, “Characterization of the SUMO-Binding Activity of the Myeloproliferative and Mental Retardation (MYM)-Type Zinc Fingers in ZNF261 and ZNF198,” PLoS One. 9(8):e105271. PMCID: PMC4136804​ PubMed

Kuang, Z., Cai, L., Zhang, X., Ji, H., Tu, BP. and Boeke, JD., 2014, “High-temporal-resolution view of transcription and chromatin states across distinct metabolic states in budding yeast,” Nat Struct Mol Biol. 21(10):854-63  PMCID: PMC4190017 ​ PubMed

Papazyan, R., Voronina, E., Chapman, JR., Luperchio, TR., Gilbert, TM., Meier, E., Mackintosh, SG., Shabanowitz, J., Tackett, AJ., Reddy, KL., Coyne, RS., Hunt, DF., Liu, Y. and Taverna, SD., 2014, “Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis,” Elife. 3:e02996. PMCID: PMC4141274 PubMed

Cieniewicz, AM., Moreland, L., Ringel, AE., Mackintosh, SG., Raman, A., Gilbert, TM., Wolberger, C., Tackett, AJ. and Taverna, SD., 2014, “The bromodomain of Gcn5 regulates site-specificity of lysine acetylation on histone H3,” Mol Cell Proteomics,13(11):2896-910.  PMCID: PMC4223480 PubMed

Gilbert, TM., McDaniel, SL., Byrum, SD., Cades, JA., Dancy, BC., Wade, H., Tackett, AJ., Strahl, BD. and Taverna, SD., 2014, “An H3K36me3 binding PWWP protein targets the NuA3 acetyltransferase complex to coordinate transcriptional elongation at coding regions,” Mol Cell Proteomics, 13(11):2883-95. PMCID: PMC4223479​ PubMed

Li, Y., Ma, Q., Cherry, CM. and Matunis, EL., 2014, “Steroid signaling promotes stem cell maintenance in the Drosophila testis,” Dev Biol. 394(1):129-41.  PMCID: PMC4165524​ PubMed

Kim, YS., Chu, Y., Han, L., Li, M., Li, Z., Lavinka, PC., Sun, S., Tang, Z., Park, K., Caterina, MJ., Ren, K., Dubner, R., Wei, F. and Dong, X., 2014, “Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain,” Neuron, 81(4):873-87.  PMCID: PMC3943838 PubMed

Debeljak, M., Freed, DN., Welch, JA., Haley, L., Beierl, K., Iglehart, BS., Pallavajjala, A., Gocke, CD., Leffell, MS., Lin, MT., Pevsner, J., Wheelan, SJ and Eshleman, JR., 2014, “Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection,” J Mol Diagn. 16(5):495-503.      PubMed 

Colis, L., Ernst, G., Sanders, S., Liu, H., Sirajuddin, P., Peltonen, K., DePasquale, M., Barrow, JC. and Laiho, M., 2014, “Design, synthesis, and structure-activity relationships of pyridoquinazolinecarboxamides as RNA polymerase I inhibitors,” J Med Chem 57(11):4950-61.​ PMCID: PMC4059246​ PubMed 

Prendergast, J., Umanah, GK., Yoo, SW., Lagerlöf, O., Motari, MG., Cole, RN., Huganir, RL., Dawson, TM., Dawson, VL. and Schnaar, RL., 2014, “Ganglioside regulation of AMPA receptor trafficking,” J Neurosci. 34(39):13246-58. PMCID: PMC4172811  PubMed

Paix, A., Wang, Y., Smith, H., Lee, CY., Calidas, D., Lu, T., Smith, J., Schmidt, H., Krause, M. and Seydoux, G., 2014, “Scalable and Versatile Genome Editing Using Linear DNAs with Micro-homology to Cas9 Sites in Caenorhabditis elegans,” Genetics, 198(4):1347-56.  PMCID: PMC4256755 PubMed

Li, Z., He, SQ., Xu, Q., Yang, F., Tiwari, V., Liu, Q., Tang, Z., Han, L., Chu, YX., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Guan, X., Wei, F., Raja, SN., Dong, X. and Guan, Y., 2014, “Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice,” Pain, 155(8):1613-21. PMCID: PMC4104261  PubMed

Gilbert, CE., Zuckerman, DM., Currier, PL. and Machamer, CE., 2014, “Three basic residues of intracellular loop 3 of the Beta-1 adrenergic receptor are required for golgin-160-dependent trafficking,” Int J Mol Sci. 15(2):2929-45. PMCID: PMC3958891 PubMed

Brubaker, SW., Gauthier, AE., Mills, EW., Ingolia, NT. and Kagan, JC.,  2014, “A Bicistronic MAVS Transcript Highlights a Class of Truncated Variants in Antiviral Immunity,” Cell. 2014 Feb 13;156(4):800-11. doi: 10.1016/j.cell.2014.01.021. PMCID: PMC3959641 PubMed

Meier, EL. and Goley, ED., 2014, “Form and function of the bacterial cytokinetic ring,” Curr Opin Cell Biol. 26C:19-27.  PubMed

Oldach, L. and Zhang, J., 2014, “Genetically Encoded Fluorescent Biosensors for Live-Cell Visualization of Protein Phosphorylation,” Chem Biol. 21(2):186-197. PMCID: PMC4050661  PubMed

Luperchio, TR., Wong, X. and Reddy, KL., 2014, “Genome regulation at the peripheral zone: lamina associated domains in development and disease,” Curr Opin Genet Dev. 25C:50-61.  Review. PubMed

Huebner, RJ. and Ewald, AJ., 2014, “Cellular foundations of mammary tubulogenesis,” Semin Cell Dev Biol, 31:124-31. Review.​ PMCID: PMC4116098 PubMed

Annaluru, N., Muller, H., Mitchell, LA., Ramalingam, S., Stracquadanio, G., Richardson, SM., Dymond, JS., Kuang, Z., Scheifele, LZ., Cooper, EM., Cai, Y., Zeller, K., Agmon, N., Han, JS., Hadjithomas, M., Tullman, J., Caravelli, K., Cirelli, K., Guo, Z., London, V., Yeluru, A., Murugan, S., Kandavelou, K., Agier, N., Fischer, G., Yang, K., Martin, JA., Bilgel, M., Bohutski, P., Boulier, KM., Capaldo, BJ., Chang, J., Charoen, K., Choi, WJ., Deng, P., DiCarlo, JE., Doong, J., Dunn, J., Feinberg, JI., Fernandez, C., Floria, CE., Gladowski, D., Hadidi, P., Ishizuka, I., Jabbari, J., Lau, CY., Lee, PA., Li, S., Lin, D., Linder, ME., Ling, J., Liu, J., Liu, J., London, M., Ma, H., Mao, J., McDade, JE., McMillan, A., Moore, AM., Oh, WC., Ouyang, Y., Patel, R., Paul, M., Paulsen, LC., Qiu, J., Rhee, A., Rubashkin, MG., Soh, IY., Sotuyo, NE., Srinivas, V., Suarez, A., Wong, A., Wong, R., Xie, WR., Xu, Y., Yu, AT., Koszul, R., Bader, JS., Boeke, JD. and Chandrasegaran, S., 2014, “Total synthesis of a functional designer eukaryotic chromosome,” Science. 344(6179):55-8. . Erratum in: Science. 2014 May 23;344(6186):816. PMCID: PMC4033833 PubMed

Hodge, DL., Berthet, C., Coppola, V., Kastenmüller, W., Buschman, MD., Schaughency, PM., Shirota, H., Scarzello, AJ., Subleski, JJ., Anver, MR., Ortaldo, JR., Lin, F., Reynolds, DA., Sanford, ME., Kaldis, P., Tessarollo, L., Klinman, DM. and Young, HA., 2014, “IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice,” J Autoimmun. 53:33-45. PMCID: PMC4148478 PubMed

Shamir, ER., Pappalardo, E., Jorgens, DM., Coutinho, K., Tsai, WT., Aziz, K., Auer, M., Tran, PT., Bader, JS. and Ewald, AJ., 2014, “Twist1-induced dissemination preserves epithelial identity and requires E-cadherin,” J Cell Biol. 204(5):839-56. PMCID: PMC3941052 PubMed

Sluch, VM. and Zack, DJ. 2014, “Stem cells, retinal ganglion cells and glaucoma,” Dev Ophthalmol. 53:111-21. PMCID: PMC4547935  PubMed

Kim, MS., Pinto, SM., Getnet, D., Nirujogi, RS., Manda, SS., Chaerkady, R., Madugundu, AK., Kelkar, DS., Isserlin, R., Jain, S., Thomas, JK., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, NA., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, LD., Patil, AH., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, SK., Marimuthu, A., Sathe, GJ., Chavan, S., Datta, KK., Subbannayya, Y., Sahu, A., Yelamanchi, SD., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, KR., Syed, N., Goel, R., Khan, AA., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, TC., Zhong, J., Wu, X., Shaw, PG., Freed, D., Zahari, MS., Mukherjee, KK., Shankar, S., Mahadevan, A., Lam, H., Mitchell, CJ., Shankar, SK., Satishchandra, P., Schroeder, JT., Sirdeshmukh, R., Maitra, A., Leach, SD., Drake, CG., Halushka, MK., Prasad, TS., Hruban, RH., Kerr, CL., Bader, GD., Iacobuzio-Donahue, CA., Gowda, H. and Pandey, A., 2014, “A draft map of the human proteome, “Nature. 509(7502):575-81. PMCID: PMC4403737 PubMed

Chivukula, RR., Shi, G., Acharya, A., Mills, EW., Zeitels, LR., Anandam, JL., Abdelnaby, AA., Balch, GC., Mansour, JC., Yopp, AC., Maitra, A. and Mendell, JT., 2014, “An Essential Mesenchymal Function for miR-143/145 in Intestinal Epithelial Regeneration,” Cell.157(5):1104-16. PMCID: PMC4175516​ PubMed

Salgado, M., Swanson, MD., Pohlmeyer, CW., Buckheit, RW 3rd., Wu, J., Archin, NM., Williams, TM., Margolis, DM., Siliciano, RF., Garcia, JV. and Blankson,  JN., 2014, “HLA-B*57 Elite Suppressor and Chronic Progressor HIV-1 Isolates Replicate Vigorously and Cause CD4+ T cell Depletion in Humanized BLT Mice,” J Virol. 88:3340-3352  PMCID: PMC3957943 PubMed

He, SQ., Han, L., Li, Z., Xu, Q., Tiwari, V., Yang, F., Guan, X., Wang, Y., Raja, SN., Dong, X. and Guan, Y., 2013, “Temporal changes in MrgC expression after spinal nerve injury,” Neuroscience. pii: S0306-4522(13)01065-8. PMCID: PMC3945476 

Lin, YC., Phua, SC., Lin, B. and Inoue, T.,  2013, “Visualizing molecular diffusion through passive permeability barriers in cells: conventional and novel approaches,” Curr Opin Chem Biol. 17(4):663-71. Review. PMCID: PMC3860267 PubMed

Su, S., Phua, SC., DeRos,e R., Chiba, S., Narita, K., Kalugin, PN., Katada, T., Kontani, K., Takeda, S. and Inoue, T., 2013, “Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia,” Nat Methods. 10(11):1105-7. PMCID: PMC3860264 PubMed

Patenaude, C., Zhang, Y., Cormack, B., Koehler, J. and Rao, R., 2013, “Essential Role for Vacuolar Acidification in Candida albicans Virulence,” J Biol Chem. 288(36):26256-64.  PMCID: PMC3764829PubMed

Frueh, DP., Goodrich, AC., Mishra, SH. and Nichols, SR., 2013, “NMR methods for structural studies of large monomeric and multimeric proteins,” Curr Opin Struct Biol., 23, 734-9. PMCID: PMC3805735PubMed

Eyler, DE., Wehner, KA. and Green, R., 2013, “Eukaryotic release factor 3 is required for multiple turnovers of peptide release catalysis by eukaryotic release factor 1,” J Biol Chem., 288(41):29530-8. PMCID: PMC3795251  PubMed

Yu, H., Lin, Z., Mattmann, ME., Zou, B., Terrenoire, C., Zhang, H., Wu, M., McManus, OB., Kass, RS., Lindsley, CW., Hopkins, CR. and Li, M., 2013, “Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels,” Proc Natl Acad Sci U S A. 110(21):8732-7. PMCID: PMC3666726 PubMed

Shirley, MD, 2013, “Concerns regarding “Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA”, Genomics. 102(4):430.  PubMed

Tu-Sekine, B., Goldschmidt, H., Petro, E. and Raben, DM., 2013, “Diacylglycerol kinase θ: regulation and stability,” Adv Biol Regul. 53(1):118-26. PMCID: PMC3992713PubMed

Berk, JM., Tifft, KE. and Wilson, KL., 2013, “The nuclear envelope LEM-domain protein emerin,” Nucleus, 4(4):298-314. PMCID: PMC3810338  PubMed

Hu, S., Wan, J., Su, Y., Song, Q., Zeng, Y., Nguyen, HN., Shin, J., Cox, E., Rho, HS., Woodard, C., Xia, S., Liu, S., Lyu, H., Ming, GL., Wade, H., Song, H., Qian, J. and Zhu, H., 2013, “DNA methylation presents distinct binding sites for human transcription factors,” Elife. 2:e00726. PMCID: PMC3762332 PubMed​

Wang, Z., Raines, LL., Hooy, RM., Roberson, H., Leahy, DJ. and Cole, PA., 2013, “Tyrosine Phosphorylation of Mig6 Reduces Its Inhibition of the Epidermal Growth Factor Receptor,” ACS Chem Biol. 8(11):2372-6. PMCID: PMC3830645PubMed

Lessard, JC., 2013, “Growth Media for E. coli,” Methods Enzymol. 533:181-9. PMID: 24182923  PubMed

Donnelly, CJ., Zhang, PW., Pham, JT., Heusler, AR., Mistry, NA., Vidensky, S., Daley, EL., Poth, EM., Hoover, B., Fines, DM., Maragakis, N., Tienari, PJ., Petrucelli, L., Traynor, BJ., Wang, J., Rigo, F., Bennett, CF., Blackshaw, S., Sattler, R. and Rothstein, JD., 2013, “RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention,” Neuron. ;80(2):415-28. PMCID: PMC4098943 PubMed

Salgado, M., Buckheit, R., Gandhi, S., Berkenblit, G., Blankson, J., 2013, “Evolution of an Attenuated HIV-1 Isolate in an Elite Suppressor,” AIDS Res Hum Retroviruses. PubMed

Lessard, JC., Piña-Paz, S., Rotty, JD., Hickerson, RP., Kaspar, RL., Balmain, A. and Coulombe, PA., 2013, “Keratin 16 regulates innate immunity in response to epidermal barrier breach,” Proc Natl Acad Sci USA, 110(48):19537-42. PMCID: PMC3845144 PubMed

Abrams, EW., Cheng, YL. and Andrew, DJ., 2013, “Drosophila KDEL Receptor Function in the Embryonic Salivary Gland and Epidermis,” PLoS One. 2013 Oct 18;8(10):e77618. PMCID: PMC3799842 PubMed

Teng, X., Dayhoff-Brannigan, M., Cheng, WC., Gilbert, CE., Sing, CN., Diny, N.L., Wheelan, SJ., Dunham, MJ., Boeke, JD., Pineda, FJ. and Hardwick, JM., 2013, “Genome-wide Consequences of Deleting Any Single Gene,” Mol Cell. 52(4):485-94. PMCID: PMC3975072     PubMed

Rath, P., Lal, B., Ajala, O., Li, Y., Xia, S., Kim, J. and Laterra, J., 2013, “In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells,” Transl Oncol. 6(2):104-11. Epub 2013 Apr 1. PMCID: PMC3612837      PubMed

Ruch, TR. and Machamer, CE., 2012, “The coronavirus E protein: assembly and beyond,” Viruses, 4(3):363-82. PMCID: PMC3347032 Pubmed 

Baile, MG. and Claypool, SM., 2013, “The power of yeast to model diseases of the powerhouse of the cell,” Front Biosci (Landmark Ed). 18:241-78. Review, PMCID: PMC3874933 PubMed

Zhang, F., Bhat, S., Gabelli, SB., Chen, X., Miller, MS., Nacev, BA., Cheng, YL., Meyers, DJ., Tenney, K., Shim, JS., Crews, P., Amzel, LM., Ma, D. and Liu, JO., 2013, “Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells,” J Med Chem. 56(10):3996-4016. PMCID: PMC3714011. PubMed

Cross, BM., Hack, A., Reinhardt, TA. and Rao, R., 2013, “SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation,” PLoS One. ;8(6):e67348. PMCID: PMC3696057 PubMed

Whited, K., Baile, MG., Currier, P. and Claypool, SM., 2013, “Seven functional classes of Barth syndrome mutation,” Hum Mol Genet. 1;22(3):483-92. PMCID: PMC3606006 PubMed

Issigonis, M. and Matunis, E., 2012, “The Drosophila BCL6 homolog Ken and Barbie promotes somatic stem cell self-renewal in the testis niche,” Dev Biol. 368(2):181-92. PMCID: PMC3402624 Pubmed

Huster, D., Kühne, A., Bhattacharjee, A., Raines, L., Jantsch, V., Noe, J., Schirrmeister, W., Sommerer, I., Sabri, O., Berr, F., Mössner, J., Stieger, B., Caca, K. and Lutsenko, S., 2012, “Diverse functional properties of Wilson disease ATP7B variants,” Gastroenterology. 142(4), 947-956. PMCID: PMC3461965 Pubmed 

Hobbs, RP., Lessard, JC. and Coulombe, PA., 2012, “Keratin intermediate filament proteins – novel regulators of inflammation and immunity in skin,” J Cell Sci.,125(Pt 22):5257-8. PMCID: PMC3561851 Pubmed

Clayton, AM., Cirimotich, CM., Dong, Y. and Dimopoulos, G., 2013, “Caudal is a negative regulator of the Anopheles IMD pathway that controls resistance to Plasmodium falciparum infection,” Dev Comp Immunol. 39(4):323-32. PMCID: PMC3892953 Pubmed

Tamura, Y., Onguka, O., Itoh, K., Endo, T., Iijima, M., Claypool, SM. and Sesaki, H., 2012, “Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P,” J Biol Chem. 287(52):43961-71. PMCID: PMC3527979 Pubmed 

Stevens, EL., Baugher, JD., Shirley, MD., Frelin, LP. and Pevsner, J., 2012, “Unexpected relationships and inbreeding in HapMap phase III populations,” PLoS One. 7(11):e49575. PMCID: PMC3501496 Pubmed

Han, L., Ma, C., Liu, Q., Weng, HJ., Cui, Y., Tang, Z., Kim, Y., Nie, H., Qu, L., Patel, KN., Li, Z., McNeil, B., He, S., Guan, Y., Xiao, B., Lamotte, RH. and Dong, X., 2013, “A subpopulation of nociceptors specifically linked to itch,” Nat Neurosci.16(2):174-82. PMCID: PMC3557753 Pubmed 

Wang, Y., Rattner, A., Zhou, Y., Williams, J., Smallwood, PM. and Nathans, J., 2012, “Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity,” Cell. 151(6):1332-44, PMCID: PMC3535266  Pubmed 

Porter, JR., Burg, JS., Espenshade, PJ. and Iglesias, PA., 2012, “Identifying a static nonlinear structure in a biological system using noisy, sparse data,” J Theor Biol. 300:232-41. PMCID: PMC3307847  Pubmed 

Phua, SC., Pohlmeyer, C. and Inoue, T., 2012, “Rapidly relocating molecules between organelles to manipulate small GTPase activity,” ACS Chem Biol. 7(12):1950-5. PMCID: PMC3528809 PubMed

Mularoni, L., Zhou, Y., Bowen, T., Gangadharan, S., Wheelan, SJ. and Boeke, JD., 2012, “Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots,” Genome Res. 22(4):693-703. doi: 10.1101/gr.129460.111. Epub 2012 Jan 4, PMCID: PMC3317151Pubmed 

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