2021

Mahadevaraju, S., Fear, JM., Akeju, M., Galletta, BJ., Pinheiro, MMLS., Avelino, CC., Cabral-de-Mello, DC., Conlon, K., Dell’Orso, S., Demere, Z., Mansuria, K., Mendonça, CA., Palacios-Gimenez, OM., Ross, E., Savery, M., Yu, K., Smith, HE., Sartorelli, V., Yang, H., Rusan, NM., Vibranovski, MD., Matunis, E., Oliver, B., 2021, Dynamic sex chromosome expression in Drosophila male germ cells, Nat Commun., 12(1):892. doi: 10.1038/s41467-021-20897-y. PMCID: PMC7873209  PubMed

Workman, RE., Pammi, T., Nguyen, BTK., Graeff, LW., Smith, E., Sebald, SM., Stoltzfus, MJ., Euler, CW., Modell, JW., 2021, A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression, Cell, 184(3):675-688.e19. doi: 10.1016/j.cell.2020.12.017. PMID: 33421369  PubMed

Goldman, DH., Livingston, NM., Movsik, J., Wu, B., Green, R., 2021, Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling, Mol Cell, S1097-2765(21)00049-6. doi: 10.1016/j.molcel.2021.01.029. PMID: 33581075  PubMed

Simonetti, FR., Zhang, H., Soroosh, GP., Duan, J., Rhodehouse, K., Hill, AL., Beg, SA., McCormick, K., Raymond, HE., Nobles, CL., Everett, JK., Kwon, KJ., White, JA., Lai, J., Margolick, JB., Hoh, R., Deeks, SG., Bushman, FD., Siliciano, JD., Siliciano, RF., 2021, Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo, J Clin Invest., 131(3):e145254. doi: 10.1172/JCI145254. PMCID: PMC7843227  PubMed

Li, S., Raychaudhuri, S., Lee, SA., Brockmann, MM., Wang, J., Kusick, G., Prater, C., Syed, S., Falahati, H., Ramos, R., Bartol, TM., Hosy, E., Watanabe, S., 2021, Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses, Nat Commun., 12(1):677. doi: 10.1038/s41467-021-21004-x. PMCID: PMC7846561  PubMed

McCausland, JW., Yang, X., Squyres, GR., Lyu, Z., Bruce, KE., Lamanna, MM., Söderström, B., Garner, EC., Winkler, ME., Xiao, J., Liu, J., 2021, Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism, Nat Commun., 12(1):609. doi: 10.1038/s41467-020-20873-y. PMCID: PMC7840769  PubMed

Yang, X., McQuillen, R., Lyu, Z., Phillips-Mason, P., De La Cruz, A., McCausland, JW., Liang, H., DeMeester, KE., Santiago, CC., Grimes, CL., de Boe,r P., Xiao, J., 2021, A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW, Nat Microbiol, doi: 10.1038/s41564-020-00853-0.  PMID: 33495624.  PubMed

Gershman, A., Romer, TG., Fan, Y., Razaghi, R., Smith, WA., Timp, W., 2021, De novo genome assembly of the tobacco hornworm moth (Manduca sexta), G3 (Bethesda), 11(1):jkaa047. doi: 10.1093/g3journal/jkaa047. PMID: 33561252  PubMed

Poll, BG., Xu, J., Jun, S., Sanchez, J., Zaidman, N., He, X., Lester, L., Berkowitz, D., Paolocci, N., Gao, WD., Pluznick, J., 2021, Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility along with Blood Pressure, J Pharmacol Exp Ther, JPET-AR-2020-000187. doi: 10.1124/jpet.120.000187. PMID: 33414131.  PubMed

2020

Watanabe, S., Davis, MW., Kusick, GF., Iwasa, J., Jorgensen, EM., 2020, SynapsEM: Computer-Assisted Synapse Morphometry, Front Synaptic Neurosci, 12:584549. doi: 10.3389/fnsyn.2020.584549. PMCID: PMC7775558  PubMed

Sarver DC, Stewart AN, Rodriguez S, Little HC, Aja S, Wong GW., 2020, “Loss of CTRP4 alters adiposity and food intake behaviors in obese mice.” Am J Physiol Endocrinol Metab. 2020 Oct 5. doi: 10.1152/ajpendo.00448.2020. Epub ahead of print. PMID: 33017221. PubMed

DiNapoli, KT., Robinson, DN., Iglesias, PA., Tools for computational analysis of moving boundary problems in cellular mechanobiology, Wiley Interdiscip Rev Syst Biol Med, e1514. doi: 10.1002/wsbm.1514. PMID: 33305503  PubMed

Osei-Owusu, IA., Norris, AL., Joynt, AT., Thorpe, J., Cho, S., Tierney, E., Schmidt, J., Hagopian, L., Harris, J., Pevsner, J., 2020, Characterization of an unbalanced translocation causing 3q28qter duplication and 10q26.2qter deletion in a patient with global developmental delay and self-injury, Cold Spring Harb Mol Case Stud., 6(6):a005884. doi: 10.1101/mcs.a005884. PMCID: PMC7784495  PubMed

Chai, Z., Silverman, D., Li, G., Williams, D., Raviola, E., Yau, KW., 2020, Light-dependent photoreceptor orientation in mouse retina, Sci Adv., 6(51):eabe2782. doi: 10.1126/sciadv.abe2782. PMCID: PMC7744070 PubMed

Phan TP, Maryniak AL, Boatwright CA, Lee J, Atkins A, Tijhuis A, Spierings DC, Bazzi H, Foijer F, Jordan PW, Stracker TH, Holland AJ., 2020, “Centrosome defects cause microcephaly by activating the 53BP1-USP28-TP53 mitotic surveillance pathway.” EMBO J. 2020 Nov 23:e106118. doi: 10.15252/embj.2020106118. Epub ahead of print. PMID: 33226141. PubMed

Lee, I., Razaghi, R., Gilpatrick, T., Molnar, M., Gershman, A., Sadowski, N., Sedlazeck, FJ., Hansen, KD., Simpson, JT., Timp, W., 2020, Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing, Nat Methods, 17(12):1191-1199. doi: 10.1038/s41592-020-01000-7. PMCID: PMC7704922 PubMed

Barrows JM, Goley ED., 2020, “FtsZ dynamics in bacterial division: What, how, and why?” Curr Opin Cell Biol. 2020 Nov 18;68:163-172. doi: 10.1016/j.ceb.2020.10.013. Epub ahead of print. PMID: 33220539. PubMed

Gonzalez-Magaldi M, McCabe JM, Cartwright HN, Sun N, Leahy DJ., 2020, “Conserved roles for receptor tyrosine kinase extracellular regions in regulating receptor and pathway activity.” Biochem J. 2020 Nov 13;477(21):4207-4220. doi: 10.1042/BCJ20200702. PMID: 33043983. PubMed

Pokrass MJ, Ryan KA, Xin T, Pielstick B, Timp W, Greco V, Regot S., 2020, “Cell-Cycle-Dependent ERK Signaling Dynamics Direct Fate Specification in the Mammalian Preimplantation Embryo.” Dev Cell. 2020 Nov 9;55(3):328-340.e5. doi: 10.1016/j.devcel.2020.09.013. Epub 2020 Oct 21. PMID: 33091369; PMCID: PMC7658051. PubMed

Umanah GKE, Ghasemi M, Yin X, Chang M, Kim JW, Zhang J, Ma E, Scarffe LA, Lee YI, Chen R, Tangella K, McNamara A, Abalde-Atristain L, Dar MA, Bennett S, Cortes M, Andrabi SA, Doulias PT, Ischiropoulos H, Dawson TM, Dawson VL., 2020, “AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF.” Cell Rep. 2020 Nov 3;33(5):108329. doi: 10.1016/j.celrep.2020.108329. PMID: 33147468. PubMed

Bell BJ, Wang AA, Kim DW, Xiong J, Blackshaw S, Wu MN., 2020, “Characterization of mWake expression in the murine brain.” J Comp Neurol. 2020 Nov 3. doi: 10.1002/cne.25066. Epub ahead of print. PMID: 33140455. PubMed

Wolfe K, Kamata R, Coutinho K, Inoue T, Sasaki AT., 2020, “Metabolic Compartmentalization at the Leading Edge of Metastatic Cancer Cells.” Front Oncol. 2020 Nov 2;10:554272. doi: 10.3389/fonc.2020.554272. PMID: 33224873; PMCID: PMC7667250. PubMed

Gliech CR, Holland AJ., 2020, ” Keeping track of time: The fundamentals of cellular clocks.” J Cell Biol. 2020 Nov 2;219(11):e202005136. doi: 10.1083/jcb.202005136. PMID: 32902596 PubMed

Velazquez, JJ., LeGraw, R., Moghadam, F., Tan, Y., Kilbourne, J., Maggiore, JC., Hislop, J., Liu, S., Cats, D., Chuva de Sousa Lopes, SM., Plaisier, C., Cahan, P., Kiani, S., Ebrahimkhani, MR., 2021, Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids, Cell Syst, 12(1):41-55.e11. doi: 10.1016/j.cels.2020.11.002. PMID: 33290741  PubMed

Jacob JT, Nair RR, Poll BG, Pineda CM, Hobbs RP, Matunis MJ, Coulombe PA., 2020, “Keratin 17 regulates nuclear morphology and chromatin organization.” J Cell Sci. 2020 Oct 30;133(20):jcs254094. doi: 10.1242/jcs.254094. PMID: 33008845; PMCID: PMC7648610. PubMed

Choi BR, Dobrowolski M, Sockanathan S. 2020 “GDE2 expression in oligodendroglia regulates the pace of oligodendrocyte maturation.” Dev Dyn. 2020 Oct 23. doi: 10.1002/dvdy.265. Online ahead of print. PMID: 33095500 PubMed

Rodriguez, S., Little, HC., Daneshpajouhnejad, P., Fenaroli, P., Tan, SY., Sarver, DC., Delannoy, M., Talbot, CC Jr., Jandu, S., Berkowitz, DE., Pluznick, JL., Rosenberg, AZ., Wong, GW., 2021, Aging and chronic high-fat feeding negatively affect kidney size, function, and gene expression in CTRP1-deficient mice, Am J Physiol Regul Integr Comp Physiol, 320(1):R19-R35. doi: 10.1152/ajpregu.00139.2020. PMCID: PMC7847058  PubMed

Vasavda C, Ho BK, Davison A., 2020, “Socially Distant Medical Education in the Face of COVID-19.” Med Sci Educ. 2020 Oct 21:1-3. doi: 10.1007/s40670-020-01127-4. Epub ahead of print. PMID: 33106763; PMCID: PMC7577518. PubMed

Bowman CE, Arany Z, Wolfgang MJ., 2020, “Regulation of maternal-fetal metabolic communication.” Cell Mol Life Sci. 2020 Oct 21. doi: 10.1007/s00018-020-03674-w. Epub ahead of print. PMID: 33084944. PubMed

Carosso GA, Boukas L, Augustin JJ, Nguyen HN, Winer BL, Cannon GH, Robertson JD, Zhang L, Hansen KD, Goff LA, Bjornsson HT., 2020, “Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome.” JCI Insight. 2019 Oct 17;4(20):e129375. doi: 10.1172/jci.insight.129375. PMID: 31465303; PMCID: PMC6824316. PubMed

Vissers C, Sinha A, Ming GL, Song H., 2020, “The epitranscriptome in stem cell biology and neural development.” Neurobiol Dis. 2020 Dec;146:105139. doi: 10.1016/j.nbd.2020.105139. Epub 2020 Oct 13. PMID: 33065280; PMCID: PMC7686257. PubMed

Patterson L, Allen J, Posey I, Shaw JJP, Costa-Pinheiro P, Walker SJ, Gademsey A, Wu X, Wu S, Zachos NC, Fox TE, Sears CL, Kester M., 2020, “Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin-induced colon epithelial cell signaling.” FASEB J. 2020 Dec;34(12):15922-15945. doi: 10.1096/fj.202001669R. Epub 2020 Oct 13. PMID: 33047400. PubMed

Luo DG, Silverman D, Frederiksen R, Adhikari R, Cao LH, Oatis JE, Kono M, Cornwall MC, Yau KW., 2020, “Apo-Opsin and Its Dark Constitutive Activity across Retinal Cone Subtypes.” Curr Biol. 2020 Oct 12:S0960-9822(20)31432-9. doi: 10.1016/j.cub.2020.09.062. Epub ahead of print. PMID: 33065015. PubMed

Daitch AK, Goley ED., 2020, “Uncovering Unappreciated Activities and Niche Functions of Bacterial Cell Wall Enzymes.” Curr Biol. 2020 Oct 5;30(19):R1170-R1175. doi: 10.1016/j.cub.2020.07.004. PMID: 33022262. PubMed

Sarver DC, Stewart AN, Rodriguez S, Little HC, Aja S, Wong GW., 2020, “Loss of CTRP4 alters adiposity and food intake behaviors in obese mice.” Am J Physiol Endocrinol Metab. 2020 Oct 5. doi: 10.1152/ajpendo.00448.2020. Epub ahead of print. PMID: 33017221. PubMed

Kusick, GF., Chin, M., Raychaudhuri, S., Lippmann, K., Adula, KP., Hujber, EJ., Vu, T., Davis, MW., Jorgensen, EM., Watanabe, S., 2020, Synaptic vesicles transiently dock to refill release sites, Nat Neurosci, 23(11):1329-1338. doi: 10.1038/s41593-020-00716-1 PMID: 32989294  PubMed

Coyne AN, Zaepfel BL, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD., 2020, “ G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD.” Neuron. 2020 Sep 23;107(6):1124-1140.e11. doi: 10.1016/j.neuron.2020.06.027. Epub 2020 Jul 15. PMID: 32673563. PubMed

Aikin TJ, Peterson AF, Pokrass MJ, Clark HR, Regot S., 2020, “MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression.” Elife. 2020 Sep 17;9:e60541. doi: 10.7554/eLife.60541. PMID: 32940599 PMCID: PMC7498266 PubMed

Silverman D, Chai Z, Yue WWS, Ramisetty SK, Bekshe Lokappa S, Sakai K, Frederiksen R, Bina P, Tsang SH, Yamashita T, Chen J, Yau KW., 2020, “Dark noise and retinal degeneration from D190N-rhodopsin.” Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23033-23043. doi: 10.1073/pnas.2010417117. Epub 2020 Sep 1. PMID: 32873651; PMCID: PMC7502766. PubMed

Thorpe J, Osei-Owusu IA, Avigdor BE, Tupler R, Pevsner J., Annu Rev Genet., 2020, ” Mosaicism in Human Health and Disease.” 2020 Sep 11. doi:10.1146/annurev-genet-041720-093403. Online ahead of print. PMID: 32916079 PubMed

Yeow, ZY., Lambrus, BG., Marlow, R., Zhan, KH., Durin, MA., Evans, LT., Scott, PM., Phan, T., Park, E., Ruiz, LA., Moralli, D., Knight, EG., Badder, LM., Novo, D., Haider, S., Green, CM., Tutt, ANJ., Lord, CJ., Chapman, JR., Holland, AJ., 2020, Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer, Nature, 585(7825):447-452. doi: 10.1038/s41586-020-2690-1. PMCID: PMC7597367   PubMed

Bryan DS, Stack M, Krysztofiak K, Cichoń U, Thomas DG, Surcel A, Schiffhauer ES, Beckett MA, Khodarev NN, Xue L, Poli EC, Pearson AT, Posner MC, Robinson DN, Rock RS, Weichselbaum RR., 2020, “4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis.”  Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22423-22429. doi: 10.1073/pnas.2014639117. Epub 2020 Aug 26. PMID: 32848073; PMCID: PMC7486788. PubMed

Hanley CJ, Henriet E, Sirka OK, Thomas GJ, Ewald AJ., 2020, “Tumor resident stromal cells promote breast cancer invasion through regulation of the basal phenotype.” Mol Cancer Res. 2020 Aug 31:molcanres.0334.2020. doi: 10.1158/1541-7786.MCR-20-0334. Online ahead of print. PMID: 32868298 PubMed

Gandhi S, Baker RP, Cho S, Stanchev S, Strisovsky K, Urban S., 2020, “Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria.” Cell Chem Biol. 2020 Aug 31:S2451-9456(20)30333-0. doi: 10.1016/j.chembiol.2020.08.011. Online ahead of print. PMID: 32888502 PubMed

Enam, SU., Zinshteyn, B., Goldman, DH., Cassani, M., Livingston, NM., Seydoux, G., Green, R., 2020, Puromycin reactivity does not accurately localize translation at the subcellular level, Elife., 9:e60303. doi: 10.7554/eLife.60303. PMCID: PMC7490009  PubMed

Thorpe J, Frelin LP, McCann M, Pardo CA, Cohen BA, Comi AM, Pevsner J., 2020, “Identification of a mosaic activating mutation in GNA11 in atypical Sturge-Weber Syndrome.” J Invest Dermatol. 2020 Aug 6:S0022-202X(20)31955-2. doi: 10.1016/j.jid.2020.03.978. Online ahead of print. PMID: 32771470 PubMed.

Ruan L, McNamara JT, Zhang X, Chang AC, Zhu J, Dong Y, Sun G, Peterson A, Na CH, Li R., 2020 “Solid-phase inclusion as a mechanism for regulating unfolded proteins in the mitochondrial matrix.” Sci Adv. 2020 Aug 5;6(32):eabc7288. doi: 10.1126/sciadv.abc7288. eCollection 2020 Aug. PMID: 32821848 PMCID: PMC7406381 PubMed.

Sinha NK, Ordureau A, Best K, Saba JA, Zinshteyn B, Sundaramoorthy E, Fulzele A, Garshott DM, Denk T, Thoms M, Paulo JA, Harper JW, Bennett EJ, Beckmann R, Green R., 2020, “EDF1 coordinates cellular responses to ribosome collisions.” Elife. 2020 Aug 3;9:e58828. doi: 10.7554/eLife.58828. PMID: 32744497; PMCID: PMC7486125. PubMed

Mihaljević L, Urban S., 2020, “Decoding the Functional Evolution of an Intramembrane Protease Superfamily by Statistical Coupling Analysis.” Structure. 2020 Aug 10:S0969-2126(20)30279-3. doi: 10.1016/j.str.2020.07.015. Online ahead of print. PMID: 32795403 PubMed.

Chin AC, Yovanno RA, Wied TJ, Gershman A, Lau AY. 2020, “D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2.” Structure. 2020 Jul 28:S0969-2126(20)30238-0. doi: 10.1016/j.str.2020.07.005. Online ahead of print. PMID: 32735769 PubMed.

Padmanaban V, Grasset EM, Neumann NM, Fraser AK, Henriet E, Matsui W, Tran PT, Cheung KJ, Georgess D, Ewald AJ., 2020, “Organotypic culture assays for murine and human primary and metastatic-site tumors.” Nat Protoc. 2020 Aug;15(8):2413-2442. doi: 10.1038/s41596-020-0335-3. Epub 2020 Jul 20. PMID: 32690957 PubMed

Silvestri, VL., Henriet, E., Linville, RM., Wong, AD., Searson, PC., Ewald, AJ., 2020, A Tissue-Engineered 3D Microvessel Model Reveals the Dynamics of Mosaic Vessel Formation in Breast Cancer, Cancer Res., 80(19):4288-4301. doi: 10.1158/0008-5472.CAN-19-1564. PMCID: PMC7541732  PubMed

Tan SY, Lei X, Little HC, Rodriguez S, Sarver DC, Cao X, Wong GW., 2020, “CTRP12 ablation differentially affects energy expenditure, body weight, and insulin sensitivity in male and female mice.” Am J Physiol Endocrinol Metab. 2020 Jul 1;319(1):E146-E162. doi: 10.1152/ajpendo.00533.2019. Epub 2020 May 18. PMID: 32421370; PMCID: PMC7468785. PubMed

Tan SY, Little HC, Sarver DC, Watkins PA, Wong GW., 2020 “CTRP12 inhibits triglyceride synthesis and export in hepatocytes by suppressing HNF-4α and DGAT2 expression.” FEBS Lett. 2020 Aug 4. doi: 10.1002/1873-3468.13895. Online ahead of print. PMID: 32749667 PubMed.

Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF., 2019, “SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL.” J Cell Biol. 2019 Jul 1;218(7):2185-2197. doi: 10.1083/jcb.201803041. PMCID: PMC6605807 PubMed.

Poll BG, Cheema MU, Pluznick JL., 2020, “Gut Microbial Metabolites and Blood Pressure Regulation: Focus on SCFAs and TMAO.” Physiology (Bethesda). 2020 Jul 1;35(4):275-284. doi: 10.1152/physiol.00004.2020. PMID: 32490748 PubMed.

Shubin CB, Greider CW., “The Role of Rif1 in telomere length regulation is separable from its role in origin firing.” Elife. 2020 Jun 29;9. pii: e58066. doi: 10.7554/eLife.58066. PMCID: PMC7371424 PubMed.

Bian Q, Cheng YH, Wilson JP, Su EY, Kim DW, Wang H, Yoo S, Blackshaw S, Cahan P., 2020, “A single cell transcriptional atlas of early synovial joint development,” Development. 2020 Jun 24. pii: dev.185777. doi: 10.1242/dev.185777. [Epub ahead of print] PMCID: PMC7390639 PubMed.

Wang, TS., Coppens, I., Saorin, A., Brady, NR., Hamacher-Brady, A., 2020, Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling, Dev Cell., 53(6):627-645.e7. doi: 10.1016/j.devcel.2020.05.014. PMCID: PMC7433306 PubMed

Zhang R, Lee DM, Jimah JR, Gerassimov N, Yang C, Kim S, Luvsanjav D, Winkelman J, Mettlen M, Abrams ME, Kalia R, Keene P, Pandey P, Ravaux B, Kim JH, Ditlev JA, Zhang G, Rosen MK, Frost A, Alto NM, Gardel M, Schmid SL, Svitkina TM, Hinshaw JE, Chen EH., 2020, “Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein.” Nat Cell Biol. 2020 Jun;22(6):674-688. doi: 10.1038/s41556-020-0519-7. Epub 2020 May 25. PMID: 32451441 PubMed

Timmons A, Fray E, Kumar M, Wu F, Dai W, Bullen CK, Kim P, Hetzel C, Yang C, Beg S, Lai J, Pomerantz JL, Yukl SA, Siliciano JD, Siliciano RF., 2020 “HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo.” Proc Natl Acad Sci U S A. 2020 Jun 22. pii: 201916290. doi: 10.1073/pnas.1916290117. PMID: 32571938 PubMed.

Zinshteyn B, Wangen JR, Hua B, Green R., 2020, “Nuclease-mediated depletion biases in ribosome footprint profiling libraries.” RNA. 2020 Oct;26(10):1481-1488. doi: 10.1261/rna.075523.120. Epub 2020 Jun 5. PMID: 32503920; PMCID: PMC7491325. PubMed

Gelsinger DR, Dallon E, Reddy R, Mohammad F, Buskirk AR, DiRuggiero J., 2020, “Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution,” Nucleic Acids Res.2020 Jun 4;48(10):5201-5216. doi: 10.1093/nar/gkaa304 PMCID: PMC7261190 PubMed.

Hunyara JL, Kolodkin AL., 2020, “Repurposing developmental mechanisms in the adult nervous system.” Curr Opin Genet Dev. 2020 May 30;65:14-21. doi: 10.1016/j.gde.2020.04.006. Review. PMID: 32485480 PubMed.

Vasavda C, Ho BK, Snyder SH., 2020, “Ease restrictions on U.S. blood donations.” Science. 2020 May 29;368(6494):957. doi: 10.1126/science.abc2322. No abstract available. PMID: 32467382 PubMed.

May, MR., Bettridge, JT., Desiderio, S., 2020, Binding and allosteric transmission of histone H3 Lys-4 trimethylation to the recombinase RAG-1 are separable functions of the RAG-2 plant homeodomain finger, J Biol Chem., 295(27):9052-9060. doi: 10.1074/jbc.RA120.014382. PMCID: PMC7335790  PubMed

Sadler E, Ryals MM, May LA, Martin D, Welsh N, Boger ET, Morell RJ, Hertzano R, Cunningham LL., 2020, “Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium.” Front Cell Neurosci. 2020 May 15;14:123. doi: 10.3389/fncel.2020.00123. eCollection 2020. PMCID: PMC7247426 PubMed.

Dresselhaus EC, Meffert MK., 2020, “Cellular Specificity of NF-κB Function in the Nervous System.” Front Immunol. 2019 May 9;10:1043. doi: 10.3389/fimmu.2019.01043. PMID: 31143184; PMCID: PMC6520659. PubMed

Lariviere PJ, Mahone CR, Santiago-Collazo G, Howell M, Daitch AK, Zeinert R, Chien P, Brown PJB, Goley ED., 2019, “An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation”, Curr Biol. 2019 May 6;29(9):1460-1470.e4. doi: 10.1016/j.cub.2019.03.066. PMCID: PMC6504580 PubMed.

Cairns L, Patterson A, Weingartner KA, Koehler TJ, DeAngelis DR, Tripp KW, Bothner B, Kavran JM., 2020 May 1, “Biophysical characterization of SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila,” J Biol Chem. 295(18):6202-6213 doi: 10.1074/jbc.RA120.012679. PubMed.

Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, Wong GW, Hankenson KD. 2020, “CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing,” J Orthop Res. 2020 May 01;38(5):996-1006. doi: 10.1002/jor.24553. Epub 2019 Dec 16. PMID: 31808575 PMCID: PMC7162724 PubMed.

White CJ, Lee J, Choi J, Chu T, Scafidi S, Wolfgang MJ. 2020, “Determining the Bioenergetic Capacity for Fatty Acid Oxidation in the Mammalian Nervous System.” Mol Cell Biol. 2020 Apr 28;40(10):e00037-20. doi: 10.1128/MCB.00037-20. Print 2020 Apr 28. PMID: 32123009 PMCID: PMC7189099 PubMed.

Barrows JM, Sundararajan K, Bhargava A, Goley ED., 2020, “FtsA Regulates Z-Ring Morphology and Cell Wall Metabolism in an FtsZ C-Terminal Linker-Dependent Manner in Caulobacter crescentus.” J Bacteriol. 2020 Mar 11;202(7):e00693-19. doi: 10.1128/JB.00693-19. PMID: 31932314; PMCID: PMC7167480. PubMed

Jiao Z, Cai H, Long Y, Sirka OK, Padmanaban V, Ewald AJ, Devreotes PN., 2020, “Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects,” Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4158-4168. doi: 10.1073/pnas.1917938117. Epub 2020 Feb 12. PubMed.

Jang Y, Elsayed Z, Eki R, He S, Du KP, Abbas T, Kai M., 2020, “Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites,” Proc Natl Acad Sci U S A. 2020 Feb 24. pii: 201913280. doi: 10.1073/pnas.1913280117. [Epub ahead of print] PubMed.

Xu Z, Green B, Benoit N, Schatz M, Wheelan S, Cormack B., 2020, “De novo genome assembly of Candida glabrata reveals cell wall protein complement and structure of dispersed tandem repeat arrays,” Mol Microbiol. 2020 Feb 18. doi: 10.1111/mmi.14488 PubMed.

Renuse S, Madugundu AK, Jung JH, Byeon SK, Goldschmidt HL, Tahir R, Meyers D, Kim DI, Cutler J, Kim KP, Wu X, Huganir RL, Pandey A., 2020, “Signature Fragment Ions of Biotinylated Peptides.” J Am Soc Mass Spectrom. 2020 Feb 5;31(2):394-404. doi: 10.1021/jasms.9b00024. Epub 2020 Jan 13. PMID: 31939678; PMCID: PMC7199424. PubMed

Padmanaban V, Tsehay Y, Cheung KJ, Ewald AJ, Bader JS. 2020 Jan 21. “Between-tumor and within-tumor heterogeneity in invasive potential.” PLoS Comput Biol.;16(1):e1007464. doi: 10.1371/journal.pcbi.1007464. PMCID: PMC6994152. PubMed.

Ruan, L., Wang, Y., Zhang, X., Tomaszewski, A., McNamara, JT., Li, R., 2020, Mitochondria-Associated Proteostasis, Annu Rev Biophys., 49:41-67. doi: 10.1146/annurev-biophys-121219-081604. PMID: 31928428 PubMed

Dobrowolski M, Cave C, Levy-Myers R, Lee C, Park S, Choi BR, Xiao B, Yang W, Sockanathan S. 2020 Jan 23. “GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRα.” Development;147(2). pii: dev180695. doi: 10.1242/dev.180695. PMID: 31932351. PMCID: PMC6983723. PubMed.

Maynard KR, Kardian A, Hill JL, Mai Y, Barry B, Hallock HL, Jaffe AE, Martinowich K. 2020 Jan 13. “TrkB signaling influences gene expression in cortistatin-expressing interneurons.” eNeuro.. pii: ENEURO.0310-19.2019. doi: 10.1523/ENEURO.0310-19.2019. PMID: 31941661. PubMed.

Lee CS, Putnam A, Lu T, He S, Ouyang JPT, Seydoux G. 2020 Jan 24. “Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins.” Elife.;9. pii: e52896. doi: 10.7554/eLife.52896. PMID: 31975687. PubMed.

Woldemeskel SA, Daitch AK, Alvarez L, Panis G, Zeinert R, Gonzalez D, Smith E, Collier J, Chien P, Cava F, Viollier PH, Goley ED. 2020 Jan 21 “The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter.” PLoS Genet.;16(1):e1008591. doi: 10.1371/journal.pgen.1008591. PMCID: PMC6994171 PubMed.

Wangen JR, Green R. 2020 Jan 23. “Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. Elife.;9. pii: e52611. doi: 10.7554/eLife.52611. PMID: 31971508. PubMed.

Putnam A, Cassani M, Smith J, Seydoux G. 2020 Jan 2. “Author Correction: A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos.” Nat Struct Mol Biol. doi: 10.1038/s41594-019-0367-y. PMID: 31896770. PubMed.

Veltri AJ, D’Orazio KN, Green R. 2020 Jan 8. “Make or break: the ribosome as a regulator of mRNA decay.” Cell Res.. doi: 10.1038/s41422-019-0271-3. PMID: 31913358. PubMed.

Park EM, Scott PM, Clutario K, Cassidy KB, Zhan K, Gerber SA, Holland AJ. 2020 Jan 6. “WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication.” J Cell Biol.;219(1). pii: e201904203. doi: 10.1083/jcb.201904203. PMID: 31874114. PubMed.

2019

Rodriguez S, Little HC, Daneshpajouhnejad P, Shepard BD, Tan SY, Wolfe A, Cheema MU, Jandu S, Woodward OM, Talbot CC Jr, Berkowitz DE, Rosenberg AZ, Pluznick JL, Wong GW. 2019 Dec 26 “Late-onset renal hypertrophy and dysfunction in mice lacking CTRP1.” FASEB J. doi: 10.1096/fj.201900558RR. PMID: 31908037. PubMed.

Howell M, Aliashkevich A, Sundararajan K, Daniel JJ, Lariviere PJ, Goley ED, Cava F, Brown PJB. 2019 Apr. “Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division.” Mol Microbiol.;111(4):1074-1092. doi: 10.1111/mmi.14212. Epub 2019 Mar 4. PMID: 30693575. PMCID: PMC6482847. PubMed.

Mohammad F, Buskirk AR., 2019 Dec 20, “Protocol for Ribosome Profiling in Bacteria,” Bio Protoc.;9(24). pii: e3468. doi: 10.21769/BioProtoc.3468. PMCID: PMC7079819 PubMed

Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. 2019 Dec. “Massive centriole production can occur in the absence of deuterosomes in multiciliated cells.” Nat Cell Biol.;21(12):1544-1552. doi: 10.1038/s41556-019-0427-x. PMID: 31792378. PMCID: PMC6913274. PubMed.

Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, Wong GW, Hankenson KD. 2019 Dec 6. “CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing.” J Orthop Res..doi:10.1002/jor.24553. [Epub ahead of print]. PMID: 31808575. PubMed.

Comert F, Greenwood A, Maramba J, Acevedo R, Lucas L, Kulasinghe T, Cairns LS, Wen Y, Fu R, Hammer J, Blazyk J, Sukharev S, Cotten ML, Mihailescu M., 2019, “The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels,” J Biol Chem. 2019 Dec 6;294(49):18557-18570. doi: 10.1074/jbc.RA119.010232. PMCID: PMC6901303 PubMed

Lee JH, Berger JM. 2019 Oct 30. “Cell Cycle-Dependent Control and Roles of DNA Topoisomerase II.” Genes (Basel).;10(11). pii: E859. doi: 10.3390/genes10110859. Review. PMCID: PMC6896119. PubMed.

Georgess D, Padmanaban V, Sirka OK, Coutinho K, Choi A, Frid G, Neumann NM, Inoue T, Ewald AJ.  2019 Nov 1 “Twist1-induced epithelial dissemination requires Prkd1 signaling.” Cancer Res. pii: canres.3241.2018. doi: 10.1158/0008-5472.CAN-18-3241. PMID: 31676574. PubMed.

Allen J, Hao S, Sears CL, Timp W. 2019 May 21. “Epigenetic Changes Induced by Bacteroides fragilis Toxin” Infect Immun.;87(6). pii: e00447-18. doi: 10.1128/IAI.00447-18. Print 2019 Jun. PMID: 30885929. PMCID: PMC6529667. PubMed.

Keener R, Connelly CJ, Greider CW. 2019 Dec. “Tel1 Activation by the MRX Complex Is Sufficient for Telomere Length Regulation but Not for the DNA Damage Response in Saccharomyces cerevisiae. Genetics. 213(4):1271-1288. doi: 10.1534/genetics.119.302713 PMCID: PMC6893380. PubMed

Bowman CE, Selen Alpergin ES, Cavagnini K, Smith DM, Scafidi S, Wolfgang MJ. 2019 Oct 29. “Maternal Lipid Metabolism Directs Fetal Liver Programming following Nutrient Stress.” Cell Rep.;29(5):1299-1310.e3. doi: 10.1016/j.celrep.2019.09.053. PMID: 31665641. PubMed.

Rodriguez S, Stewart AN, Lei X, Cao X, Little HC, Fong V, Sarver DC, Wong GW. 2019, “PRADC1: a novel metabolic-responsive secretory protein that modulates physical activity and adiposity.” FASEB J. 2019 Dec;33(12):14748-14759. doi: 10.1096/fj.201901279R.  PMCID: PMC6894076 PubMed

Carosso GA, Boukas L, Augustin JJ, Nguyen HN, Winer BL, Cannon GH, Robertson JD, Zhang L, Hansen KD, Goff LA, Bjornsson HT. 2019 “Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome.” JCI Insight. 2019 Oct 17;4(20):e129375. doi: 10.1172/jci.insight.129375. PMID: 31465303  PubMed

Le TT, Gao X, Park SH, Lee J, Inman JT, Lee JH, Killian JL, Badman RP, Berger JM, Wang MD., 2019, “Synergistic Coordination of Chromatin Torsional Mechanics and Topoisomerase Activity,” Cell. ;179(3):619-631.e15. doi: 10.1016/j.cell.2019.09.034 PMCID: PMC6899335 PubMed

Wang Z, Hutcherson SM, Yang C, Jattani RP, Tritapoe JM, Yang YK, Pomerantz JL., 2019, “Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling,” J Biol Chem. 2019 Oct 4;294(40):14648-14660. doi: 10.1074/jbc.RA119.009551. PMCID: PMC6779434 PubMed

Kothari P, Johnson C, Sandone C, Iglesias PA, Robinson DN. 2019, “How the mechanobiome drives cell behavior, viewed through the lens of control theory.” J Cell Sci. 2020 Sep 2 132(17). pii: jcs234476. doi: 10.1242/jcs.234476. Review. PMID: 31477578. PMCID: PMC6771144  PubMed.

Frandolig JE, Matney CJ, Lee K, Kim J, Chevée M, Kim SJ, Bickert AA, Brown SP., 2019, “The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina.” Cell Rep. 2019 Sep 17;28(12):3131-3143.e5. doi:10.1016/j.celrep.2019.08.048. PMID: 31533036 PMCID: PMC6941480 PubMed

Padmanaban V, Krol I, Suhail Y, Szczerba BM, Aceto N, Bader JS, Ewald AJ. 2019 Sep. “E-cadherin is required for metastasis in multiple models of breast cancer.” Nature. 573(7774):439-444. doi: 10.1038/s41586-019-1526-3. Epub 2019 Sep 4. PMID: 31485072. PubMed.

Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, Gordon M, Meirman R, Millan-Zambrano G, Ayestaran I, Salguero I, Sharan R, Li R, Kupiec M, Jackson SP. 2019 Sep. “Genome architecture and stability in the Saccharomyces cerevisiae knockout collection.” Nature. 573(7774):416-420. doi: 10.1038/s41586-019-1549-9. PMCID: PMC6774800. PubMed.

Ouyang JPT, Folkmann A, Bernard L, Lee CY, Seroussi U, Charlesworth AG, Claycomb JM, Seydoux G., 2019, “P Granules Protect RNA Interference Genes from Silencing by piRNAs.” Dev Cell. 2019 Sep 23;50(6):716-728.e6. doi: 10.1016/j.devcel.2019.07.026. PMCID: PMC6764750 PubMed

Surcel A, Schiffhauer ES, Thomas DG, Zhu Q, DiNapoli KT, Herbig M, Otto O, West-Foyle H, Jacobi A, Kräter M, Plak K, Guck J, Jaffee EM, Iglesias PA, Anders RA, Robinson DN., 2019, “Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14.” Cancer Res. 2019 Sep 15;79(18):4665-4678. doi: 10.1158/0008-5472.CAN-18-3131., PMCID: PMC6744980 PubMed

Tan Y, Cahan P. 2019 Aug 28. “SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species.” Cell Syst.;9(2):207-213.e2. doi: 10.1016/j.cels.2019.06.004. Epub 2019 Jul 31. PMID: 31377170. PMCID: PMC6715530.  PubMed

Vissers C, Kageyama R. 2019 Aug 19. “Bursting the Notch Bubble: New Insights into In Vivo Transcriptional Dynamics.” Dev Cell.;50(4):393-394. doi: 10.1016/j.devcel.2019.07.028. PMID: 31430449. PubMed.

Pike AM, Strong MA, Ouyang JPT, Greider CW. 2019 Aug 5. “TIN2 functions with TPP1/POT1 to stimulate telomerase processivity.” Mol Cell Biol.. pii: MCB.00593-18. doi: 10.1128/MCB.00593-18. PMCID: PMC6791651. PubMed

Pundir P, Liu R, Vasavda C, Serhan N, Limjunyawong N, Yee R, Zhan Y, Dong X, Wu X, Zhang Y, Snyder SH, Gaudenzio N, Vidal JE, Dong X. 2019 Jul 10. “A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity.” Cell Host Microbe.;26(1):114-122.e8. doi: 10.1016/j.chom.2019.06.003. Epub 2019 Jul 2. PMID: 31278040. PMCID: PMC6649664. PubMed.

Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, Snyder SH. 2019 Jul 23. “Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.” Cell Chem Biol. pii: S2451-9456(19)30218-1. doi: 10.1016/j.chembiol.2019.07.006. [Epub ahead of print] PMID: 31353321. PubMed.

Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DN, Seydi M, Gottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF. 2019 Jul 10. “The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.” Cell Host Microbe.;26(1):73-85.e4. doi: 10.1016/j.chom.2019.06.005. PMID: 31295427. PMCID: PMC6724192 PubMed.

Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC. 2019 Jul 23. “FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.” Cell Rep.;28(4):845-854.e5. doi: 10.1016/j.celrep.2019.06.072. PMID: 31340148. PubMed.

Hayward D, Kouznetsova VL, Pierson HE, Hasan NM, Guzman ER, Tsigelny IF, Lutsenko S., 2019 Jul 23, “ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.” J Biol Chem. 2019 Sep 27;294(39):14454-14466. doi: 10.1074/jbc.RA119.008231. PMCID: PMC6768640 PubMed

Little HC, Rodriguez S, Lei X, Tan SY, Stewart AN, Sahagun A, Sarver DC, Wong GW., 2019, “Myonectin deletion promotes adipose fat storage and reduces liver steatosis” FASEB J. 2019 Jul;33(7):8666-8687. doi: 10.1096/fj.201900520R PMCID: PMC6593887 PubMed

Johnson DM, Andrew DJ. 2019 Jun 26. “Role of tbc1 in Drosophila embryonic salivary glands.” BMC Mol Cell Biol. 20(1):19. doi: 10.1186/s12860-019-0198-z. PMCID: PMC6595604. PubMed.

Allen J, Sears CL. 2019 Feb 25. “Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development.” Genome Med. 20(1):19. doi: 10.1186/s12860-019-0198-z. PMID: 30803449. PMCID: PMC6388476. PubMed

Zhu L*, Liao SE*, Fukunaga R. 2019 Jun 23. “Drosophila Regnase-1 RNase is required for mRNA and miRNA profile remodelling during larva-to-adult metamorphosis.” RNA Biol. 1-15. doi: 10.1080/15476286.2019.1630799. [Epub ahead of print], PMCID: PMC6542536, *equal contribution. PubMed

Kodani A, Moyer T, Chen A, Holland A, Walsh CA, Reiter JF. 2019 Jun 13. “SFI1 promotes centriole duplication by recruiting USP9X to stabilize the microcephaly protein STIL.” J Cell Biol. pii: jcb.201803041. doi: 10.1083/jcb.201803041. [Epub ahead of print]. PMID: 31197030. PubMed.

D’Orazio KN, Wu CC, Sinha N, Loll-Krippleber R, Brown GW, Green R. 2019 Jun 20. “The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay.” Elife. 8. pii: e49117. doi: 10.7554/eLife.49117. PMCID: PMC6598757. PubMed.

Zieman AG, Poll BG, Ma J, Coulombe PA. 2019 Jul 1. “Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.” Hum Mol Genet. 28(13):2255-2270. doi: 10.1093/hmg/ddz050. PMCID: PMC6602407. PubMed

Dresselhaus EC, Meffert MK., 2019 May 9. “Cellular Specificity of NF-κB Function in the Nervous System.” Front Immunol, 10:1043. doi: 10.3389/fimmu.2019.01043. eCollection 2019. Review. PMCID: PMC6520659. PubMed.

Weaver J, Mohammad F, Buskirk AR, Storz G, 2019 Mar 5. “Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes.” MBio, 10(2). pii: e02819-18. doi: 10.1128/mBio.02819-18. PMCID: PMC6401488. PubMed.

Meixiong J, Vasavda C, Snyder SH, Dong X., 2019 May 21. “MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.” Proc Natl Acad Sci USA, 116(21):10525-10530. doi: 10.1073/pnas.1903316116. PMCID: PMC6535009 PubMed.

DeFelice MM*, Clark HR*, Hughey JJ*, Maayan I, Kudo T, Gutschow MV, Covert MW, Regot S., 2019 Apr 30. “NF-κB signaling dynamics is controlled by a dose-sensing autoregulatory loop.” Sci Signal. 12(579). pii: eaau3568. doi: 10.1126/scisignal.aau3568. *equal contribution. PubMed.

Moyer TC, Holland AJ., 2019 May 22. “PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall.” Elife, 8. pii: e46054. doi: 10.7554/eLife.46054. [Epub ahead of print]. PMCID: PMC6570480  PubMed.

Zhu L, Liao SE, Ai Y, Fukunaga R, 2019 May 30. “RNA methyltransferase BCDIN3D is crucial for female fertility and miRNA and mRNA profiles in Drosophila ovaries.”, PLoS One.14(5):e0217603. doi: 10.1371/journal.pone.0217603. eCollection 2019. PMCID: PMC6542536 PubMed.

Syu GD, Wang SC, Ma G, Liu S, Pearce D, Prakash A, Henson B, Weng LC, Ghosh D, Ramos P, Eichinger D, Pino I, Dong X, Xiao J, Wang S, Tao N, Kim KS, Desai PJ, Zhu H., 2019 Apr 30, “Development and application of a high-content virion display human GPCR array.” Nat Commun.;10(1):1997. doi: 10.1038/s41467-019-09938-9. PMCID: PMC6491619  PubMed.

Latallo MJ, Livingston NM, Wu B., 2019, “Translation imaging of single mRNAs in established cell lines and primary cultured neurons.” Methods. 2019 Jun 1;162-163:12-22. doi: 10.1016/j.ymeth.2019.03.021. Epub 2019 Mar 21. Review. PMID: 30905747 PubMed

Bowman CE, Scafidi J, Scafidi S., 2019, ”Metabolic perturbations after pediatric TBI: It’s not just about glucose”, Exp Neurol. Review. 316:74-84. PubMed

Clister T, Greenwald EC, Baillie GS, Zhang J., 2019 Jun 20, “AKAP95 Organizes a Nuclear Microdomain to Control Local cAMP for Regulating Nuclear PKA”, Cell Chem Biol. 26(6):885-891.e4. doi: 10.1016/j.chembiol.2019.03.003. PMCID: PMC6588460. PubMed

Bowman CE, Selen Alpergin ES, Ellis JM, Wolfgang MJ., 2019 Nov 1, “Loss of ACOT7 potentiates seizures and metabolic dysfunction”, Am J Physiol Endocrinol Metab. 317(5):E941-E951. doi: 10.1152/ajpendo.00537.2018. PMCID: PMC6879868. PubMed

Liao SE, Kandasamy SK, Zhu L, Fukunaga R. 2019 Jul.”DEAD-box RNA helicase Belle posttranscriptionally promotes gene expression in an ATPase activity-dependent manner.” RNA.;25(7):825-839. doi: 10.1261/rna.070268.118. Epub 2019 Apr 12. PMID: 30979781. PMCID: PMC6573787. PubMed.

Lariviere PJ, Mahone CR, Santiago-Collazo G, Howell M, Daitch AK, Zeinert R, Chien P, Brown PJB, Goley ED., 2019, “An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation”, Curr Biol. pii: S0960-9822(19)30394-X. PubMed

Patel SP, Vasavda C, Ho B, Meixiong J, Dong X, Kwatra SG., 2019, “Cholestatic pruritus: Emerging mechanisms and therapeutics”, J Am Acad Dermatol. pii: S0190-9622(19)30627-9. Review. PubMed

Cook EK, Sell GL, Schaffer TB, Margolis SS., 2019 Apr, “The emergence of Ephexin5 as a therapeutic target in Alzheimer’s disease.” Expert Opin Ther Targets. 23(4):263-265. PMCID: PMC6715421 PubMed

Calzada, E.,Avery E, Sam PN, Modak A, Wang C, McCaffery JM, Han X, Alder NN, Claypool SM., 2019, “Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc1 complex function.” Nat Commun. 10(1):1432 PMCID: PMC6441012 PubMed

Putnam A, Cassani M, Smith J, Seydoux G. 2019, “A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos,” Nat Struct Mol Biol. (3):220-226. doi: 10.1038/s41594-019-0193-2. Epub 2019 Mar 4. PMID: 30833787. PMCID: PMC6668929  PubMed

Allen J, Hao S, Sears CL, Timp W., 2019, “Epigenetic changes induced by Bacteroides fragilis toxin (BFT).” Infect Immun. pii: IAI.00447-18. PubMed

Westerbeck JW, Machamer CE., 2019, “The Infectious Bronchitis Coronavirus Envelope Protein Alters Golgi pH to Protect Spike Protein and Promote Release of Infectious Virus.” J Virol.  pii: JVI.00015-19. PubMed

Yue WWS*, Silverman D*, Ren X, Frederiksen R, Sakai K, Yamashita T, Shichida Y, Cornwall MC4, Chen J, Yau KW., 2019 “Elementary response triggered by transducin in retinal rods.” Proc Natl Acad Sci U S A. 116(11):5144-5153 PMCID: PMC6421417 *equal contribution PubMed

Bartee D, Sanders S, Phillips PD, Harrison MJ, Koppisch AT, Freel Meyers CL., 2019, “Enamide Prodrugs of Acetyl Phosphonate Deoxy-d-xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents.” ACS Infect Dis. 5(3):406-417, PMCID: PMC6592275.  PubMed

Worden EJ, Hoffmann NA, Hicks CW, Wolberger C. 2019 Mar 7. “Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.” Cell.;176(6):1490-1501.e12. doi: 10.1016/j.cell.2019.02.002. Epub 2019 Feb 11. PMID: 30765112. PMCID: PMC6498860. PubMed.

Schiffhauer, ES., Ren, Y., Iglesias, V., Kothari, P., Iglesias, PA. and Robinson, DN., 2019, “Myosin IIB assembly-state determines myosin IIB mechanosensitive dynamics,” J. Cell Biol.218(3):895-908, PMCID: PMC6400566. PubMed

Vissers C, Ming GL, Song H., 2019, “Nanoparticle technology and stem cell therapy team up against neurodegenerative disorders.” Adv Drug Deliv Rev. 2019 Aug;148:239-251. doi: 10.1016/j.addr.2019.02.007. Epub 2019 Feb 21. PMID: 30797953; PMCID: PMC6703981. PubMed

Tao Y, Kang B, Petkovich DA, Bhandari YR, In J, Stein-O’Brien G, Kong X, Xie W, Zachos N, Maegawa S, Vaidya H, Brown S, Chiu Yen RW, Shao X, Thakor J, Lu Z, Cai Y, Zhang Y, Mallona I, Peinado MA, Zahnow CA, Ahuja N, Fertig E, Issa JP, Baylin SB, Easwaran H., 2019, “Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis.” Cancer Cell. 35(2):315-328.e6. PMID: 30753828. PMCID: PMC6636642. PubMed 

Zhang W, Zhang X, Xue Z, Li Y, Ma Q, Ren X, Zhang J, Yang S, Yang L, Wu M, Ren M, Xi R, Wu Z, Liu JL, Matunis E, Dai J, Gao G., 2019, “Probing the Function of Metazoan Histones with a Systematic Library of H3 and H4 Mutants.” Dev Cell. 48(3):406-419.e5. PubMed

Mohammad F, Green R, Buskirk AR., 2019 Feb 6, “A systematically-revised ribosome profiling method for bacteria reveals pauses at single-codon resolution.” Elife. 8. pii: e42591. PMCID: PMC6377232  PubMed

Kreutzberger AJB, Ji M, Aaron J, Mihaljević L, Urban S., 2019 Feb 1, “Rhomboid distorts lipids to break the viscosity-imposed speed limit of membrane diffusion. Science. 363(6426). pii: eaao0076. doi: 10.1126/science.aao0076. PMCID: PMC6368390  PubMed

Bruner KM, Wang Z, Simonetti FR, Bender AM, Kwon KJ, Sengupta S, Fray EJ, Beg SA, Antar AAR, Jenike KM, Bertagnolli LN, Capoferri AA, Kufera JT, Timmons A, Nobles C, Gregg J, Wada N, Ho YC, Zhang H, Margolick JB, Blankson JN, Deeks SG, Bushman FD, Siliciano JD, Laird GM, Siliciano RF., 2019, “A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.” Nature. 566(7742):120-125. PMID: 30700913. PMCID: PMC6447073. PubMed

Shubitowski TB, Poll BG, Natarajan N, Pluznick JL., 2019 Feb, “Short-chain fatty acid delivery: assessing exogenous administration of the microbiome metabolite acetate in mice,” Physiol Rep.7(4):e14005. doi: 10.14814/phy2.14005. PMCID: PMC6391713 PubMed

Howell M, Aliashkevich A, Sundararajan K, Daniel JJ, Lariviere PJ, Goley ED, Cava F, Brown PJB., 2019, “Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division. Mol Microbiol doi: 10.1111/mmi.14212. PubMed

Kothari, P., Srivastava, V., Aggarwal, V., Tchernyshyov, I., Van Eyk, J., Ha, T., and Robinson, DN., 2019, “Contractility kits promote assembly of the mechanoresponsive cytoskeletal network,” J. Cell Sci.  132(2): 1-12, PMCID: PMC6362397. PubMed

Meixiong J, Vasavda C, Green D, Zheng Q, Qi L, Kwatra SG, Hamilton JP, Snyder SH, Dong X., 2019, “Identification of a bilirubin receptor that may mediate a component of cholestatic itch.” Elife. 8. pii: e44116. PubMed

Avin BA, Wang Y, Gilpatrick T, Workman RE, Lee I, Timp W, Umbricht CB, Zeiger MA. 2019 Aug. “Characterization of human telomerase reverse transcriptase promoter methylation and transcription factor binding in differentiated thyroid cancer cell lines.” Genes Chromosomes Cancer.;58(8):530-540. doi: 10.1002/gcc.22735. PMID: 30664813. PMCID: PMC6621557. PubMed.

Capowski EE, Samimi K, Mayerl SJ, Phillips MJ, Pinilla I, Howden SE, Saha J, Jansen AD, Edwards KL, Jager LD, Barlow K, Valiauga R, Erlichman Z, Hagstrom A, Sinha D, Sluch VM, Chamling X, Zack DJ, Skala MC, Gamm DM. 2019 Jan 9. “Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.” Development. 146(1). pii: dev171686. doi: 10.1242/dev.171686. PMID: 3056793. PMCID: PMC6340149. PubMed.

Wied, TJ., Chin, AC. and Lau, AY., 2019, “High Conformational Variability in the GluK2 Kainate Receptor Ligand-Binding Domain,” Structure, 27(1):189-195.e2. doi: 10.1016/j.str.2018.09.008. PMCID: PMC6363114, PubMed

Lilley, BN., Sabbah, S., Hunyara, JL., Gribble, KD., Al-Khindi, T., Xiong, J., Wu, Z., Berson, DM., Kolodkin, AL., 2019 Jan 1, “Genetic access to neurons in the accessory optic system reveals a role for Sema6A in midbrain circuitry mediating motion perception,” J Comp Neurol. 527(1):282-296. doi: 10.1002/cne.24507. PMCID: PMC6312510 PubMed

Bowman CE, Wolfgang MJ., 2019 Jan, “Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.” Adv Biol Regul. 71:34-40. Review. PMCID: PMC6347522 PubMed

2018

Calzada, E., McCaffery, J.M. and Claypool, S. (2018). Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc1 complex function. bioRxiv (Pre-print), 269233; doi: Link

Ogunbona, O. B., Baile, M. G., & Claypool, S. M. (2018). Cardiomyopathy-associated mutation in the ADP/ATP carrier reveals translation-dependent regulation of cytochrome c oxidase activity. Molecular biology of the cell, 29(12), 1449-1464. PMCID: PMC6014099 PubMed

Ward, A., Kumari, G., Sen, R., Desiderio, S., 2018, “The RAG-2 Inhibitory Domain Gates Accessibility of the V(D)J Recombinase to Chromatin,” Mol Cell Biol. 38 (15) e00159-18; PMCID: PMC6048317 PubMed

Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, Dore LC, Dong Q, Zheng W, Jin P, Wu H, Shen B, Zhuang X, He C, Liu K, Song H, Ming GL., 2018, “Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System,” Neuron, 97(2):313-325 PMCID: PMC5777326 PubMed

Tutucci E, Livingston NM, Singer RH, Wu B., 2018, “Imaging mRNA In Vivo, from Birth to Death,” Annu Rev Biophys. 47:85-106 PubMed

Chevée, M., Robertson, J. J., Cannon, G. H., Brown, S. P., & Goff, L. A. (2018). Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons. Cell reports, 22(2), 441-455. PMCID: PMC5863578 PubMed

Buss, J., Coltharp, C., Huang, T., Pohlmeyer, C., Wang, SC., Hatem, C. and Xiao, J., 2013, “In vivo organization of the FtsZ-ring by ZapA and ZapB revealed by quantitative super-resolution microscopy,” Mol Microbiol. 89(6):1099-120. PMCID: PMC3894617  PubMed

Moyer, T., Kandels-Lewis, S., Ohta, M., Kitagawa, D., Holland, AJ., Karsenti, E., Lorca, T., Lince-Faria, M. and Bettencourt-Dias, M., 2016, “CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis,”  Curr Biol. 26(9):1127-37. PMCID: PMC4867225 PubMed

Adivarahan, S., Livingston, N., Nicholson, B., Rahman, S., Wu, B., Rissland, OS. and Zenklusen, D., 2018, “Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway,”Mol Cell. 72(4):727-738.e5. PMID: 30415950 PubMed

Wang, Y., Cho, C., Williams, J., Smallwood, PM., Zhang, C., Junge, HJ. and Nathans, J., 2018, “Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance,” Proc Natl Acad Sci U S A.pii: 201813217.  PMID: 30478038 PubMed

Schaffer, TB., Smith, JE., Cook, EK., Phan, T. and Margolis, SS., 2018, “PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5,” Cell Rep. 25(9):2470-2483.e8. PMID: 30485813. PMCID: PMC6371982 PubMed

Bedsaul, JR., Carter, NM., Deibel, KE., Hutcherson, SM., Jones, TA., Wang, Z., Yang, C., Yang, YK. and Pomerantz, JL., 2018, “Mechanisms of Regulated and Dysregulated CARD11 Signaling in Adaptive Immunity and Disease,” Front Immunol. doi: 10.3389/fimmu.2018.02105. eCollection 2018. Review. PMID: 30283447. PMCID: PMC6156143 PubMed

Zhu, L., Kandasamy, SK., Liao, SE. and Fukunaga, R., 2018, “LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes,” Nat Commun. 9(1):4031. PMCID: PMC6168497 PubMed 

 

Schmidt, K., Ralle, M., Schaffer, T., Jayakanthan, S., Bari, B., Muchenditsi, A. and Lutsenko, S., 2018, “ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal DOPAMINE-β-HYDROXYLASE,” J Biol Chem. pii: jbc.RA118.004889. PMID: 30341172 PubMed

Prasad, S.Huang, J.Zeng, Q.Brooks, BR., 2018, An explicit-solvent hybrid QM and MM approach for predicting pKa of smallmolecules in SAMPL6 challenge, J Comput Aided Mol Des. 32(10):1191-1201, PMID: 30276503. PubMed

 

Braun, E., Gilmer, J., Mayes, H., Mobley, D., Monroe, J., Samarjeet, S.P., Zuckerman, D., 2018, Best Practices for Foundations in Molecular Simulations 

Salvatierra J, Diaz-Bustamante M, Meixiong J, Tierney E, Dong X, Bosmans F. 2018 Dec 3. “A disease mutation reveals a role for NaV1.9 in acute itch.” J Clin Invest. 128(12):5434-5447. doi: 10.1172/JCI122481. Epub 2018 Nov 5. PMID: 30395542. PMCID: PMC6264633. PubMed

Chevée M, Brown SP. 2018 Dec. “The development of local circuits in the neocortex: recent lessons from the mouse visual cortex.” Curr Opin Neurobiol. 53:103-109. PMID: 30053693. PMCID: PMC6427921. PubMed

Tammia M, Mi R, Sluch VM, Zhu A, Chung T, Shinn D, Zack DJ, Höke A, Mao HQ. 2018 “Egr2 overexpression in Schwann cells increases myelination frequency in vitro,” Heliyon. 4(11):e00982 PubMed

Ryals M, Morell RJ, Martin D, Boger ET, Wu P, Raible DW, Cunningham LL., 2018, “The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity.” Front Cell Neurosci. 12:445. PubMed

Prasad S, Huang J, Zeng Q, Brooks BR. 2018 Oct 1. “An explicit-solvent hybrid QM and MM approach for predicting pKa of small molecules in SAMPL6 challenge.” J Comput Aided Mol Des.;32(10):1191-1201. doi: 10.1007/s10822-018-0167-1.PMID: 30276503. PMCID: PMC6342563. PubMed.

Chen S, Luperchio TR, Wong X, Doan EB, Byrd AT, Roy Choudhury K, Reddy KL, Krangel MS. (2018) “A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus,” Cell Rep. 25(7):1729-1740.e6. PMID: 30428344. PMCID: PMC6287930. PubMed

Metz KA, Teng X, Coppens I, Lamb HM, Wagner BE, Rosenfeld JA, Chen X, Zhang Y, Kim HJ, Meadow ME, Wang TS, Haberlandt ED, Anderson GW, Leshinsky-Silver E, Bi W, Markello TC, Pratt M, Makhseed N, Garnica A, Danylchuk NR, Burrow TA, Jayakar P, McKnight D, Agadi S, Gbedawo H, Stanley C, Alber M, Prehl I, Peariso K, Ong MT, Mordekar SR, Parker MJ, Crooks D, Agrawal PB, Berry GT, Loddenkemper T, Yang Y, Maegawa GHB, Aouacheria A, Markle JG, Wohlschlegel JA, Hartman AL, Hardwick JM. 2018 Nov. “KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect.” Ann Neurol.;84(5):766-780. doi: 10.1002/ana.25351. Epub 2018 Nov 8. PMID: 30295347. PubMed

Phua, SC., Nihongaki, Y. and Inoue, T., 2018, “Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides,” Curr Opin Cell Biol.; 50:72-78. PMCID: PMC5911401 PubMed

Tung B, Ma D, Wang S, Oyinlade O, Laterra J, Ying M, Lv SQ, Wei S, Xia S., 2018, “Krüppel-like factor 9 and histone deacetylase inhibitors synergistically induce cell death in glioblastoma stem-like cells.” BMC Cancer. 18(1):1025. PubMed

Zhu, J., Tsai, HJ., Gordon, MR., Li, R., 2018, “Cellular Stress Associated with Aneuploidy,” Dev Cell. 44(4):420-431. PMID: 29486194 PubMed

Wu, M., Hayward, D., Kalin, JH., Song, Y., Schwabe, JW., Cole, PA., 2018, “Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex,” Elife. 7. pii: e37231. PMCID: PMC6019071 PubMed

Salvatierra, J., Castro, J., Erickson, A., Li, Q., Braz, J., Gilchrist, J., Grundy, L., Rychkov, GY., Deiteren, A., Rais, R., King, GF., Slusher, BS., Basbaum, A., Pasricha, PJ., Brierley, SM. and Bosmans, F., 2018, “NaV1.1 inhibition can reduce visceral hypersensitivity,” JCI Insight. 3(11). pii: 121000. PMCID: PMC6124407 PubMed

 Liao, SE. and Fukunaga, R., 2018, “Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro,” Methods Mol Biol. 1680:101-121. PMID: 29030844 PubMed

Levine, MS. and Holland, AJ., 2018, “The impact of mitotic errors on cell proliferation and tumorigenesis,” Genes Dev.;32(9-10):620-638. PMCID: PMC6004076 [Available on 2018-11-01] PubMed

Duan, R., Kim, JH., Shilagardi, K., Schiffhauer, ES., Lee, DM., Son, S., Li, S., Thomas, C., Luo, T., Fletcher, DA., Robinson, DN. and Chen, EH., 2018, “Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion,” Nat Cell Biol. 20(6):688-698. PMID: 29802406 PubMed

Lambrus, BG., Moyer, TC. and Holland, AJ., 2018, “Applying the auxin-inducible degradation system for rapid protein depletion in mammalian cells,” Methods Cell Biol. 144:107-135. 5. PMID: 29804665 PubMed

Sanders, S., Bartee, D., Harrison, MJ., Phillips, PD., Koppisch, AT. and Freel Meyers, CL., 2018, “Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors,” PLoS One. 13(5):e0197638. PMCID: PMC5957436 PubMed

Schuller, AP. and Green, R., 2018, “Roadblocks and resolutions in eukaryotic translation,” Nat Rev Mol Cell Biol. PMCID: PMC6054806 [Available on 2019-02-01] PubMed

Neumann, NM., Perrone, MC., Veldhuis, JH., Huebner, RJ., Zhan, H., Devreotes, PN., Brodland, GW., and Ewald, AJ., 2018, “Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation,” Dev Cell. 45(1):67-82.e6. PMCID: PMC5983037 [Available on 2019-04-09] PubMed

Little HC, Tan SY, Cali FM, Rodriguez S, Lei X, Wolfe A, Hug C, Wong GW., 2018, “Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle”, Mol Cell Proteomics. 17(8):1546-1563. PMCID: PMC6072542. PubMed                      

Liao, SE., Ai, Y. and Fukunaga, R., 2018, “An RNA-binding protein Blanks plays important roles in defining small RNA and mRNA profiles in Drosophila testes,” Heliyon. 2018 Jul 25;4(7):e00706. eCollection. PMCID: PMC6074722 PubMed

Ramachandran, KV., Fu, JM., Schaffer, TB., Na, CH., Delannoy, M. and Margolis, SS., 2018, “Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome,” Mol Cell. 71(1):169-177.e6. PMCID: PMC6070390 [Available on 2019-07-05] PubMed

Sundararajan, K., Vecchiarelli, A., Mizuuchi, K. and Goley, ED., 2018, “Species- and C-terminal linker-dependent variations in the dynamic behavior of FtsZ on membranes in vitro,” Mol Microbiol. PMID: 30010220. PMCID: PMC6195856. PubMed

Divakaruni, AS., Hsieh, WY., Minarrieta, L., Duong, TN., Kim, KKO., Desousa, BR., Andreyev, AY., Bowman, CE., Caradonna, K., Dranka, BP., Ferrick, DA., Liesa, M., Stiles, L., Rogers, GW., Braas, D., Ciaraldi, TP., Wolfgang, MJ., Sparwasser, T., Berod, L., Bensinger, SJ. and Murphy, AN., 2018, “Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis,” Cell Metab. 2018 Jun 16. pii: S1550-4131(18)30383-8.  PMCID: PMC6125190 [Available on 2019-09-04] PubMed

Sirka OK, Shamir ER, Ewald AJ. 2018 Oct 1. “Myoepithelial cells are a dynamic barrier to epithelial dissemination.” J Cell Biol. 217(10):3368-3381. doi: 10.1083/jcb.201802144. Epub 2018 Jul 30. PMID: 30061105. PMCID: PMC6168248. PubMed.

Eldred KC, Hadyniak SE, Hussey KA, Brenerman B, Zhang PW, Chamling X, Sluch VM, Welsbie DS, Hattar S, Taylor J, Wahlin K, Zack DJ, Johnston RJ Jr. 2018 “Thyroid hormone signaling specifies cone subtypes in human retinal organoids,” Science. 362(6411). PubMed

Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. 2018 Sep 4. “Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis.”Cell Metab.;28(3):490-503.e7. doi: 10.1016/j.cmet.2018.06.001. Epub 2018 Jun 28. PMID: 30043752. PMCID: PMC6125190. PubMed.

Fligor CM, Langer KB, Sridhar A, Ren Y, Shields PK, Edler MC, Ohlemacher SK, Sluch VM, Zack DJ, Zhang C, Suter DM, Meyer JS., 2018, “Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells.” Sci Rep. 8(1):14520. PubMed

Veenhuis RT, Kwaa AK, Garliss CC, Latanich R, Salgado M, Pohlmeyer CW, Nobles CL, Gregg J, Scully EP, Bailey JR, Bushman FD, Blankson JN. 2018 Sep 20. “Long-term remission despite clonal expansion of replication-competent HIV-1 isolates.” JCI Insight.;3(18). pii: 122795. doi: 10.1172/jci.insight.122795. eCollection 2018 Sep 20. PMID: 30232278. PMCID: PMC6237238. PubMed.

Zhou Y, Bond AM, Shade JE, Zhu Y, Davis CO, Wang X, Su Y, Yoon KJ, Phan AT, Chen WJ, Oh JH, Marsh-Armstrong N, Atabai K, Ming GL, Song H. 2018 Sep 6. “Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool.” Cell Stem Cell. 23(3):444-452.e4. doi: 10.1016/j.stem.2018.08.005. Epub 2018 Aug 30. PMID: 30174295. PMCID: PMC6128767. PubMed.

Greenspan LJ, Matunis EL., 2018, “Retinoblastoma Intrinsically Regulates Niche Cell Quiescence, Identity, and Niche Number in the Adult Drosophila Testis.” Cell Rep. 24(13):3466-3476.e8. PubMed

Wei S, Wang J, Oyinlade O, Ma D, Wang S, Kratz L, Lal B, Xu Q, Liu S, Shah SR, Zhang H, Li Y, Quiñones-Hinojosa A, Zhu H, Huang ZY, Cheng L, Qian J, Xia S., 2018, “Heterozygous IDH1R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP.” Oncogene. 37(38):5160-5174. PubMed

Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, Bosmans F. 2018 Jun 7. “NaV1.1 inhibition can reduce visceral hypersensitivity” JCI Insight 3(11). pii: 121000. doi: 10.1172/jci.insight.121000. eCollection 2018 Jun 7. PMID: 29875317. PMCID: PMC6124407. PubMed.

Dadi H, Jones TA, Merico D, Sharfe N, Ovadia A, Schejter Y, Reid B, Sun M, Vong L, Atkinson A, Lavi S, Pomerantz JL, Roifman CM. 2018 May. “Combined immunodeficiency and atopy caused by a dominant negative mutation in caspase activation and recruitment domain family member 11 (CARD11).” J Allergy Clin Immunol.;141(5):1818-1830.e2. doi: 10.1016/j.jaci.2017.06.047. Epub 2017 Aug 19. PMID: 28826773. PubMed.

El-Diwany R, Soliman M, Sugawara S, Breitwieser F, Skaist A, Coggiano C, Sangal N, Chattergoon M, Bailey JR, Siliciano RF, Blankson JN, Ray SC, Wheelan SJ, Thomas DL, Balagopal A. 2018 Aug 1. “CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans.” Sci Adv. 4(8):eaat0843. doi: 10.1126/sciadv.aat0843. eCollection 2018 Aug. PMID: 30083606. PMCID: PMC6070316. PubMed.

Goodwin CR, Rath P, Oyinlade O, Lopez H, Mughal S, Xia S, Li Y, Kaur H, Zhou X, Ahmed AK, Ho S, Olivi A, Lal B., 2018, “Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts.” Clin Neurol Neurosurg. 171:26-33. PubMed

Han L, Limjunyawong N, Ru F, Li Z, Hall OJ, Steele H, Zhu Y, Wilson J, Mitzner W, Kollarik M, Undem BJ, Canning BJ, Dong X., 2018 Mar. “Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyper-responsiveness.” Nat Neurosci, 21(3):324-328. doi: 10.1038/s41593-018-0074-8. PMCID: PMC5857222. PubMed.

Gonzalez-Hurtado E, Lee J, Choi J, Wolfgang MJ., 2018 Jan, “Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing.” Mol Metab, doi: 10.1016/j.molmet.2017.11.004. PMCID: PMC5784326. PubMed.

Cairns, L., Tran, T., Fowl, BH., Patterson, A., Kim, YJ., Bothner, B. and Kavran, JM., 2018, “Salvador has an extended SARAH domain that mediates binding to Hippo kinase,” J Biol Chem. pii: jbc.RA117.000923. PMCID: PMC5900767 PubMed

Oldach, LM., Gorshkov, K., Mills, WT. 4th,  Zhang, J. and Meffert, MK., 2018, “A Biosensor for MAPK-Dependent Lin28 Signaling,” Mol Biol Cell. pii: mbc.E17-08-0500. PMCID: PMC5935066 PubMed

Yoon, KJ., Vissers, C., Ming, GL. and Song, H., 2018, “Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence,” J Cell Biol. pii: jcb.201802117. Review. PMCID: PMC5987727 PubMed

Kalin, JH., Wu, M., Gomez, AV., Song, Y., Das, J., Hayward, D., Adejola, N., Wu, M., Panova, I., Chung, HJ., Kim, E., Roberts, HJ., Roberts, JM., Prusevich, P., Jeliazkov, JR., Roy Burman, SS., Fairall, L., Milano, C., Eroglu, A., Proby, CM., Dinkova-Kostova, AT., Hancock, WW., Gray, JJ., Bradner, JE., Valente, S., Mai, A., Anders, NM., Rudek, MA., Hu, Y., Ryu, B., Schwabe, JWR., Mattevi, A., Alani, RM. and Cole, PA., 2018, “Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors,” Nat Commun. 9(1):53. PMCID: PMC5754352 PubMed

Uzoma, I., Hu, J., Cox, E., Xia, S., Zhou, J., Rho, HS., Guzzo, C., Paul, C., Ajala, O., Goodwin, CR., Jeong, J., Moore, C., Zhang, H., Meluh, P., Blackshaw, S., Matunis, M., Qian, J., Zhu, H., 2018, “Global Identification of SUMO Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration,” Mol Cell Proteomics. pii: mcp.RA117.000014. PMCID: PMC5930406 Pubmed

West-Foyle, H., Kothari, P., Osborne, J. and Robinson, DN., 2018, “14-3-3 proteins tune non-muscle myosin II assembly,” J Biol Chem. pii: jbc.M117.819391. PMCID: PMC5936829 PubMed

Ruan, L., Zhang, X. and Li, R., 2018, “Recent insights into the cellular and molecular determinants of aging,” J Cell Sci. 131(3). pii: jcs210831. doi: 10.1242/jcs.210831. Review. PMCID: PMC5826050 PubMed

Islam, N. and Garza, LA., 2018, “Adipose and Hair Function: An aPPARent Connection,” J Invest Dermatol. 138(3):480-482. PMID: 29477189 PubMed

Gilbert, CE., Sztul, E., Machamer, CE., 2018, “Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins,” Mol Biol Cell. pii: mbc.E17-11-0622. PMCID: PMC5896932 [Available on 2018-06-30] PubMed

Sluch VM, Chamling X, Wenger C, Duan Y, Rice DS, Zack DJ., 2018, “Highly efficient scarless knock-in of reporter genes into human and mouse pluripotent stem cells via transient antibiotic selection”, PLoS One. 13(11):e0201683. PMCID: PMC6264506. PubMed

Oyinlade O, Wei S, Lal B, Laterra J, Zhu H, Goodwin CR, Wang S, Ma D, Wan J, Xia S. 2018, “Targeting UDP-α-D-glucose 6-dehydrogenase inhibits glioblastoma growth and migration.” Oncogene. 37(20):2615-2629. PubMed

Dresselhaus EC, Boersma MCH, Meffert MK. 2018 Apr 25. “Targeting of NF-κB to Dendritic Spines Is Required for Synaptic Signaling and Spine Development” J Neurosci.;38(17):4093-4103. doi: 10.1523/JNEUROSCI.2663-16.2018. Epub 2018 Mar 19. PMID: 29555853. PMCID: PMC5963848. PubMed.

Schuller AP, Zinshteyn B, Enam SU, Green R. 2018 Feb 28. “Directed hydroxyl radical probing reveals Upf1 binding to the 80S ribosomal E site rRNA at the L1 stalk.” Nucleic Acids Res.; 46(4):2060-2073. doi: 10.1093/nar/gkx1263. PMID: 29253221. PMCID: PMC5829565 PubMed.

Pohlmeyer CW, Laskey SB, Beck SE, Xu DC, Capoferri AA, Garliss CC, May ME, Livingston A, Lichmira W, Moore RD, Leffell MS, Butler NJ, Thorne JE, Flynn JA, Siliciano RF, Blankson JN. 2018, “Cross-reactive microbial peptides can modulate HIV-specific CD8+ T cell responses.” PLoS One. 13(2):e0192098. PubMed

Daniszewski M, Senabouth A, Nguyen QH, Crombie DE, Lukowski SW, Kulkarni T, Sluch VM, Jabbari JS, Chamling X, Zack DJ, Pébay A, Powell JE, Hewitt AW., 2018, “Single cell RNA sequencing of stem cell-derived retinal ganglion cells.” Sci Data. 5:180013. PubMed

Gonzalez-Hurtado E, Lee J, Choi J, Wolfgang MJ. 2018, “Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing,” Mol Metab. 45-56. PubMed

2017

Yourik, P., Aitken, CE., Zhou, F., Gupta, N., Hinnebusch, AG. and Lorsch, JR., 2017, “Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity,” Elife. 6. pii: e31476. PMCID: PMC5726853 PubMed

Vissers, C., Ming, GL. and Song, H., 2017, “Stem cells take the stairs,” J Biol Chem. 292(48):19605-19606. PMCID: PMC5712602 PubMed

Scherer, PC., Zaccor, NW., Neumann, NM., Vasavda, C., Barrow, R., Ewald, AJ., Rao, F., Sumner, CJ. and Snyder, SH., 2017, “TRPV1 is a physiological regulator of μ-opioid receptors,”  Proc Natl Acad Sci U S A. 114(51):13561-13566. PMCID: PMC5754810  PubMed

Schuller, AP., Zinshteyn, B., Enam, SU. and Green, R., 2017, “Directed hydroxyl radical probing reveals Upf1 binding to the 80S ribosomal E site rRNA at the L1 stalk,” Nucleic Acids Res. PMCID: PMC5829565 PubMed

Kim, DI., Cutler, JA., Na, CH., Reckel, S., Renuse, S., Madugundu, AK., Tahir, R., Goldschmidt, HL., Reddy, KL., Huganir, RL., Wu, X., Zachara, NE., Hantschel, O. and Pandey, A., 2017, “BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation,” J Proteome Res. PMCID: PMC6092923 PubMed

Wan, J., Su, Y., Song, Q., Tung, B., Oyinlade, O., Liu, S., Ying, M., Ming, G. L., Song, H., Qian, J., Zhu, H.,  Xia, S. (2017). Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration. eLife, 6, e20068. doi:10.7554/eLife.20068 PubMed

Nakamura, H., Lee, A. A., Afshar, A. S., Watanabe, S., Rho, E., Razavi, S., Suarez, A., Lin, Y. C., Tanigawa, M., Huang, B., DeRose, R., Bobb, D., Hong, W., Gabelli, S. B., Goutsias, J., Inoue, T. (2017). Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions. Nature materials, 17(1), 79-89. PMCID: PMC5916848 PubMed

Avin, B., Sahli, Z., Zeiger, M., 2017, “Molecular Biology of Endocrine Tumors,” In V.T. DeVita, S.A. Rosenberg, T.S. Lawrence (Eds) Cancer: Principles and Practice of Oncology (Chapter 7), 11th Ed., Philadelphia, PA: Wolters Kluwer ISBN 9781496394637

Lee, CS., Lu, T. and Seydoux, G., 2017, “Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B,” Elife. 6. pii: e30201. PMCID: PMC5734877 PubMed

Sundararajan, K. and Goley, ED., 2017 Oct., “The intrinsically disordered C-terminal linker of FtsZ regulates protofilament dynamics and superstructure in vitro.,” J Biol Chem. pii: jbc.M117.809939. PMCID: 5733589 (available on 2018-12-15)  PubMed

Levine, M. and Holland, A., 2017, “Cell cycle proteins moonlight in multiciliogenesis,” Science. 358(6364):716-718. No abstract available. PMCID: PMC5749915 PubMed

Lariviere, PJ., Szwedziak, P., Mahone, CR., Löwe, J. and Goley, ED., 2017, “FzlA, an essential regulator of FtsZ filament curvature, controls constriction rate during Caulobacter division,” Mol Microbiol. PMCID: PMC5760450 PubMed

Surcel, A., Schiffhauer, E.S., Thomas, D., Zhu, Q., DiNapoli, K., Herbig, M., Otto, O., Guck, J. Jaffee, E., Iglesias, P., Anders, R. and Robinson, D., 2017, “Harnessing the adaptive potential of mechanoresponsive proteins to overwhelm pancreatic cancer dissemination and invasion,” bioRxiv. 

Burr, R., Ribbens, D., Raychaudhuri, S., Stewart, EV., Ho, J. and Espenshade, PJ., 2017, “Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast,” J Biol Chem. 292(39):16333-16350. PMCID: PMC5625062 PubMed

Clasen, SJ., Shao, W., Gu, H. and Espenshade, P., 2017, “Prolyl dihydroxylation of pre-ribosomal uS12/Rps23 regulates fungal hypoxic adaptation,” Elife. 6. pii: e28563. PMCID: PMC5690285 PubMed

 

Lee, JH., Wendorff, TJ. and Berger, JM., 2017, “Resveratrol: a novel type of topoisomerase II inhibitor,” J Biol Chem. pii: jbc.M117.810580. PMCID: PMC5743075 (available on 2018-12-22) PubMed

Greenspan, LJ. and Matunis, EL., 2017, “Live Imaging of the Drosophila Testis Stem Cell Niche,” Methods Mol Biol. 1463:63-74. PMID: 27734347 PubMed

Kuzmichev, YV., Veenhuis, RT., Pohlmeyer, CW., Garliss, CC., Walker- Sperling, VE., Blankson, JN., 2017, “A CD3/CD28 microbead-based HIV-1 viral outgrowth assay,” J Virus Erad. 3(2):85-89. PMCID: PMC5384271. PubMed

Walker-Sperling, VE., Pohlmeyer, CW., Veenhuis, RT., May, M., Luna, KA., Kirkpatrick, AR., Laeyendecker, O., Cox, AL., Carrington, M., Bailey, JR., Arduino, RC. and Blankson, JN., 2017, “Factors Associated With the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller,”  EBioMedicine. 16:141-149. PMCID: PMC5474502 PubMed

Yoon, KJ., Ringeling, FR., Vissers, C., Jacob, F., Pokrass, M., Jimenez-Cyrus, D., Su, Y., Kim, NS., Zhu, Y., Zheng, L., Kim, S., Wang, X., Doré, LC., Jin, P., Regot, S., Zhuang, X., Canzar, S., He, C., Ming, GL. and Song, H., 2017, “Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation,” Cell. 201pii: S0092-8674(17)31052-8 PMCID: PMC5679435 (available 2018-11-02) PubMed

Ogunbona, OB., Onguka, O., Calzada, E. and Claypool, SM., 2017, “Multitiered and Cooperative Surveillance of Mitochondrial Phosphatidylserine Decarboxylase 1,” Mol Cell Biol. 2017 37(17). pii: e00049-17. PMCID: PMC5559681 PubMed 

Meier, EL., Daitch, AK., Yao, Q., Bhargava, A., Jensen, GJ. and Goley, ED., 2017, “FtsEX-mediated regulation of the final stages of cell division reveals morphogenetic plasticity in Caulobacter crescentus,” PLoS Genet. 13(9):e1006999. PMCID: PMC5607218 PubMed

Kim, SP., Li, Z., Zoch, ML., Frey, JL., Bowman, CE., Kushwaha, P., Ryan, KA., Goh, BC., Scafidi, S., Pickett, JE., Faugere, MC., Kershaw, EE., Thorek, DLJ., Clemens, TL., Wolfgang, MJ. and Riddle, RC., 2017, “Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner,” JCI Insight. 2(16). pii: 92704. PMCID:PMC5621897 PubMed

Burr, R. and Espenshade, PJ., 2017, “Oxygen-responsive transcriptional regulation of lipid homeostasis in fungi: Implications for anti-fungal drug development,” Semin Cell Dev Biol. pii: S1084-9521(17)30201-X. PMCID: PMC5826825 PubMed

Nguyen-Ngoc, KV., Silvestri, VL., Georgess, D., Fairchild, AN. and Ewald, AJ., “Mosaic loss of non-muscle myosin IIA and IIB is sufficient to induce mammary epithelial proliferation,” J Cell Sci. pii: jcs.208546. PMCID: PMC5665442 PubMed

Miao, C., Schiffhauer, ES., Okeke, EI., Robinson, DN. and Luo, T., 2017, “Parallel Compression Is a Fast Low-Cost Assay for the High-Throughput Screening of Mechanosensory Cytoskeletal Proteins in Cells,” ACS Appl Mater Interfaces. 9(34):28168-28179. 21. PMCID:PMC5891216 PubMed

 Cho, C., Smallwood, PM. and Nathans, J., 2017, “Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation,” Neuron. 95(5):1056-1073.e5. PMID: 28803732 PubMed

Yoon, KJ., Song, G., Qian, X., Pan, J., Xu, D., Rho, HS., Kim, NS., Habela, C., Zheng, L., Jacob, F., Zhang, F., Lee, EM., Huang, WK., Ringeling, FR.,Vissers, C., Li, C., Yuan, L., Kang, K., Kim, S., Yeo, J., Cheng, Y., Liu, S., Wen, Z., Qin, CF., Wu, Q., Christian, KM., Tang, H., Jin, P., Xu, Z., Qian, J., Zhu, H., Song and H., Ming, GL., 2017 Sep 7. “Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins,” Cell Stem Cell. pii: S1934-5909(17)30293-X. PMCID: PMC5600197 PubMed

Kothari, P., Schiffhauer, ES. and Robinson, DN., 2017, “Cytokinesis from nanometers to micrometers and microseconds to minutes,” Methods Cell Biol.137:307-322

Sluch VM, Chamling X, Liu MM, Berlinicke CA, Cheng J, Mitchell KL, Welsbie DS, Zack DJ. 2017 Nov. “Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells.” Stem Cells Transl Med. 6(11):1972-1986. doi:10.1002/sctm.17-0059. Epub 2017 Oct 10. PMID: 29024560. PMCID: PMC6430043. PubMed.

Lei, X., Seldin, MM., Little, HC., Choy, N., Klonisch, T., and Wong, GW., 2017, “C1q/TNF-related protein 6 (CTRP6) links obesity to adipose tissue inflammation and insulin resistance,” J Biol Chem. jbc.M116.766808. PMCID: 5592665

Lee, J., Choi, J., Selen Alpergin, ES., Zhao, L., Hartung, T., Scafidi, S., Riddle, RC., Wolfgang, MJ., 2017, “Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance,” Cell Rep. 20(3):655-667. PMCID: 25546239 PubMed

Sanders, S., Vierling, RJ., Bartee, D., DeColli, AA., Harrison, MJ., Aklinski, JL., Koppisch, AT. and Freel Meyers, CL., 2017, “Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase,” ACS Infect Dis. PMCID: PMC5650741 PubMed

Schuller, AP., and Green, R., 2017, “The ABC(E1)s of Ribosome Recycling and Reinitiation,” Mol Cell. 66(5):578-580. PMID: 28575655 PubMed

Welsbie, DS., Mitchell, KL., Jaskula-Ranga, V., Sluch, VM., Yang, Z., Kim, J., Buehler, E., Patel, A., Martin, SE., Zhang, PW., Ge, Y., Duan, Y., Fuller, J., Kim, BJ., Hamed, E., Chamling, X., Lei, L., Fraser, IDC., Ronai, ZA., Berlinicke, CA. and Zack, DJ., 2017, “Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons,” Neuron. 94(6):1142-1154.e6O PMCID: PMC5553555 PubMed

Vasavda, C., Zaccor, NW., Scherer, PC., Sumner, CJ. and Snyder, SH., 2017, 2017, “Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding,” mJ Vis Exp. 2017 Jun 9;(124). PMID: 28654029 PubMed

McClary, B., Zinshteyn, B., Meyer, M., Jouanneau, M., Pellegrino, S., Yusupova, G., Schuller, A., Reyes, JCP., Lu, J., Guo, Z., Ayinde, S., Luo, C., Dang, Y., Romo, D., Yusupov, M., Green, R., and Liu, JO., 2017, “Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A,” Cell Chem Biol. 24(5):605-613.e5. PMCID: PMC5562292  PubMed

Sundararajan K, and Goley ED, 2017, “Cytoskeletal Proteins in Caulobacter crescentus: Spatial Orchestrators of Cell Cycle Progression, Development, and Cell Shape,” Subcell Biochem. 84:103-137. PMcID: PMC5554946 PubMed

Jernberg, JN., Bowman, CE., Wolfgang, MJ., and Scafidi, SJ., 2017, “Developmental regulation and localization of Carnitine Palmitoyltransferases (CPTs) in rat brain,” Neurochem. PMCID: PMC5927624 PubMed

Ramachandran, K. and Margolis SS., 2017, “A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function,” Nat Struct Mol Biol. PMCID: PMC5383508   PubMed

Sell, GL., Schaffer, TB., and Margolis, SS., 2017 “Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer’s-like impairment in mice,” J Clin Invest. pii: 85504. PMCID: PMC5409082 PubMed

El-Diwany, R., Breitwieser, FP., Soliman, M., Skaist, AM., Srikrishna, G., Blankson, JN., Ray, SC., Wheelan, SJ., Thomas, DL., and Balagopal, A., 2017, “Intracellular HIV-1 rna and CD4+ t cell activation in patients starting antiretrovirals,”  AIDS. PMCID: PMC5572749 PubMed

Cox, E., Hwang, W., Uzoma, I., Hu, J., Guzzo, C., Jeong, J., Matunis, M., Qian, J., Zhu, H., and Blackshaw, S., 2017, “Global analysis of SUMO-binding proteins identifies SUMOylation as a key regulator of the INO80 chromatin remodeling complex,” Mol Cell Proteomics. pii: mcp.M116.063719. PMCID: PMC5417823 PubMed

Lu, YW., Acoba, MG., Selvaraju, K., Huang, TC., Nirujogi, RS., Sathe, G., Pandey, A.,and Claypool, SM., 2017, “Human adenine nucleotide translocases physically and functionally interact with respirasomes,” Mol Biol Cell. pii: mbc.E17-03-0195. PMCID: PMC5449148 PubMed

Goodrich, AC., Meyers, DJ. and Frueh, DP., 2-17, “Molecular Impact of Covalent Modifications on Nonribosomal Peptide Synthetase Carrier Protein Communication,” J Biol Chem. 2017 Apr 28. pii: jbc.M116.766220.PMCID: PMC5473208 PubMed

Radley, AH., Schwab, RM., Tan, Y., Kim, J., Lo, EKW., Cahan, P.,2017, “Assessment of engineered cells using CellNet and RNA-seq,” Nat Protoc. 12(5):1089-1102. PMCID: PMC5765439 PubMed

Bowman, CE., Rodriguez, S., Selen Alpergin, ES., Acoba, MG., Zhao, L., Hartung, T., Claypool, SM., Watkins, PA., and Wolfgang, MJ., 2017, “The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency,” Cell Chem Biol. pii: S2451-9456(17)30109-5. PMCID: PMC5482780 PubMed

Schuller, A.P., Wu, C.C., Dever, T.E., Buskirk, A.R. & Green, R., 2017, eIF5A functions globally in translation elongation and termination. Molecular Cell 66, 194–205. PMCID: PMC5414311  PubMed

Ruan, L., Zhou, C., Jin, E., Kucharavy, A., Zhang, Y., Wen, Z., Florens, L., Li, R., 2017, “Cytosolic proteostasis through importing of misfolded proteins into mitochondria,” Nature. PMCID: PMC5793917 PubMed​

Cairns, L., Tran, T. and Kavran, JM., 2017, “Structural Insights into the Regulation of Hippo Signaling,” ACS Chem Biol. PubMed

Lambrus, BG. and Holland, AJ., 2017, “A New Mode of Mitotic Surveillance,” Trends Cell Biol. pii: S0962-8924(17)30014-4. PMCID: PMC5403546 PubMed

Petersen, PS., Lei, X., Wolf, RM., Rodriguez, S., Tan, SY., Little, HC., Schweitzer, MA., Magnuson, TH., Steele, KE. and Wong, GW., 2017, “CTRP7 deletion attenuates obesity-linked glucose intolerance, adipose tissue inflammation, and hepatic stress,” Am J Physiol Endocrinol Metab. ajpendo.00344.2016. PMID: PMC5406989 PubMed

Bettridge, J., Na, CH., Pandey, A. and Desiderio, S., 2017, “H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase,” Proc Natl Acad Sci U S A. 114(8):1904-1909. PMCID: PMC5338453 PubMed

Burr, R., Stewart, EV. and Espenshade, PJ., 2017, “Coordinate Regulation of Yeast Sterol Regulatory Element-Binding Protein (SREBP) and Mga2 Transcription Factors,” J Biol Chem. 2017 Feb 15. pii: jbc.M117.778209. PMCID: PMC5392677 PubMed

Mills, EW., Green, R. and Ingolia, NT., 2017, “Slowed decay of mRNAs enhances platelet specific translation,” Blood. pii: blood-2016-08-736108. PMCID: PMC5409447 PubMed

Gonzalez-Hurtado, E., Lee, J., Choi, J., Selen Alpergin, ES., Collins, SL., Horton, MR. and Wolfgang, MJ., 2017, “The Loss Of Macrophage Fatty Acid Oxidation Does Not Potentiate Systemic Metabolic Dysfunction,” Am J Physiol Endocrinol Metab :ajpendo.00408.2016. PMCID: PMC5451524 PubMed

El-Diwany, R., Cohen, VJ., Mankowski, MC., Wasilewski, LN., Brady, JK., Snider, AE., Osburn, WO., Murrell, B., Ray, SC., Bailey, JR., 2017, “Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1,” PLoS Pathog. 13(2):e1006235. PMCID: PMC5342271 PubMed

Li, Z., Tseng, PY., Tiwari, V., Xu, Q., He, SQ., Wang, Y., Zheng, Q., Han, L., Wu, Z., Blobaum, AL., Cui, Y., Tiwari, V., Sun, S., Cheng, Y., Huang-Lionnet, JH., Geng, Y., Xiao, B., Peng, J., Hopkins, C., Raja, SN., Guan, Y. and Dong, X., 2017, “Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain,” Proc Natl Acad Sci U S A. pii: 201615255. PMCID: PMC5347560 PubMed

Bachas, S., Kohrs, B. and Wade, HV.,2017, “Unconventional coupling between ligand recognition and allosteric control in the multidrug resistance gene regulator, BmrR,” ChemMedChem. PubMed​

Phua, SC., Chiba, S., Suzuki, M., Su, E., Roberson, EC., Pusapati, GV., Setou, M., Rohatgi, R., Reiter, JF., Ikegami, K. and Inoue, T., 2017, “Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision,” Cell. 168(1-2):264-279.e15. PMCID: PMC5660509 PubMed

Levine, MS., Bakker, B., Boeckx, B., Moyett, J., Lu, J., Vitre, B., Spierings, DC., Lansdorp, PM., Cleveland, DW., Lambrechts, D., Foijer, F. and Holland, AJ., 2017, “Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals,” Dev Cell. pii: S1534-5807(16)30917-0. PMCID: PMC5296221 PubMed

Schiffhauer, ES. and Robinson, DN., 2017, “Mechanochemical Signaling Directs Cell-Shape Change,”  Biophys J. 112(2):207-214. Review. PMCID: PMC5266144 PubMed

Peng, YJ., Zhang, X., Gridina, A., Chupikova, I., McCormick, DL., Thomas, RJ., Scammell, TE., Kim, G., Vasavda, C., Nanduri, J., Kumar, GK., Semenza, GL., Snyder, SH. and Prabhakar, NR., 2017, “Complementary roles of gasotransmitters CO and H2S in sleep apnea,” Proc Natl Acad Sci U S A. pii: 201620717. PMCID: PMC5307452 PubMed

Kumar, P., Tan., Y. and Cahan, P., 2017, “Understanding development and stem cells using single cell-based analyses of gene expression,” Development. 144(1):17-32. PMCID: PMC5278625 PubMed

Prasad, TS., Mohanty, AK., Kumar, M., Sreenivasamurthy, SK., Dey, G., Nirujogi, RS., Pinto, SM., Madugundu, AK., Patil, AH., Advani, J., Manda, SS., Gupta, MK., Dwivedi, SB., Kelkar, DS., Hall, B., Jiang, X., Peery, A., Rajagopalan, P., Yelamanchi, SD., Solanki, HS., Raja, R., Sathe, GJ., Chavan, S., Verma, R., Patel, KM., Jain, AP., Syed, N., Datta, KK., Khan, AA., Dammalli, M., Jayaram, S., Radhakrishnan, A., Mitchell, CJ., Na, CH., Kumar, N., Sinnis, P., Sharakhov, IV., Wang, C., Gowda, H., Tu, Z., Kumar, A. and Pandey, A., 2016, “Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes,” Genome Res. 27(1):133-144. PMCID: PMC5204337 PubMed

Burr, R., Stewart, EV., Shao, W., Zhao, S., Hannibal-Bach, HK., Ejsing, CS. and Espenshade, PJ., 2016, “Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast,” J Biol Chem. 291(23):12171-83. PMCID: PMC4933267 PubMed

Smith, J., Calidas, D., Schmidt, H., Lu, T., Rasoloson, D. and Seydoux, G., 2016, “Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3,” Elife. 5. pii: e21337. PMCID:PMC5262379  PubMed

2016

Jouanneau, M., McClary, B., Reyes, J.C.P., Chen, R., Chen, Y., Plunkett, W., Cheng, X., Milinichik, A.Z., Albone, E.F., Liu, J.O., Romo, D. (2016). Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe. Bioorg. Med. Chem. Lett. 26(8):2092-7 PMCID: PMC5522753 PubMed

Yoon, KJ., Ringeling, FR., Vissers, C., Jacob, F., Pokrass, M., Jimenez-Cyrus, D., Su, Y., Kim, NS., Zhu, Y., Zheng, L., Kim, S., Wang, X., Dore, LC., Jin, P. Regot, S., Zhuang, X., Canzar, S., He, C., Ming, GL., and Song, H., 2017, “Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation,” Cell.  pii: S0092-8674(17)31052-8. PMCID: PMC5679435 PubMed

König, G., Pickard, FC.Huang, J.Simmonett, AC.Tofoleanu, F.Lee, J.Dral, PO.Prasad, S., Jones, M., Shao, Y.Thiel, W.Brooks, BR., 2016, Calculating distribution coefficients based on multi-scale free energy simulations: an evaluation of MM and QM/MM explicit solvent simulations of water-cyclohexanetransfer in the SAMPL5 challenge, J Comput Aided Mol Des. 2016 Nov;30(11):989-1006. PMID: 27577746 PubMed

 

Cox, PM. and Bumpus, NN., 2016, “Single Heteroatom Substitutions in the Efavirenz Oxazinone Ring Impact Metabolism by CYP2B6,” ChemMedChem. PMID: 27860311. PubMed​

Su, Z., Wang, F., Lee, JH., Stephens, KE., Papazyan, R., Voronina, E., Krautkramer, KA., Raman, A., Thorpe, JJ., Boersma, MD., Kuznetsov, VI., Miller, MD., Taverna, SD., Phillips, GN. Jr. and Denu, JM., 2016, “Reader domain specificity and lysine demethylase-4 family function,” Nat Commun. 7:13387. PMCID: PMC5114558.  ​PubMed

Tan, SY., Little, HC., Lei, X., Li, S., Rodriguez, S. and Wong, GW., 2016, “Partial deficiency of CTRP12 alters hepatic lipid metabolism,” Physiol Genomics. :physiolgenomics.00111.2016.​ PubMed

Schiffhauer, ES., Luo, T., Mohan, K., Srivastava, V., Qian, X., Griffis, ER., Iglesias, PA., Robinson, DN., 2016, “Mechanoaccumulative Elements of the Mammalian Actin Cytoskeleton,” Curr Biol. 26(11):1473-9. PMID: 27185555 PubMed​

Chen, Z., Dempsey, DR., Thomas, SN., Hayward, D., Bolduc, DM. and Cole, PA., 2016, “Molecular Features of Phosphatase and Tensin Homolog (PTEN) Regulation by C-terminal Phosphorylation,” J Biol Chem. (27):14160-9. PMCID: PMC4933174 PubMed

Shen, Y., Stracquadanio, G., Wang, Y., Yang, K., Mitchell, LA., Xue, Y., Cai, Y., Chen, T., Dymond, JS., Kang, K., Gong, J., Zeng, X., Zhang, Y., Li, Y., Feng, Q., Xu, X., Wang, J., Wang, J., Yang, H., Boeke, JD. and Bader, JS., 2016, “SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes,” Genome Res. 26(1):36-49. PMID: 26566658 ​PubMed

Lambrus, BG., Daggubati, V., Uetake, Y., Scott, PM., Clutario, KM., Sluder, G. and Holland, AJ., 2016, “A USP28-53BP1-p53-p21 signaling axis arrestsgrowth after centrosome loss or prolonged mitosis,” J Cell Biol. 214(2):143-53. PMID: 27432896 PubMed

Shamir, ER., Coutinho, K., Georgess, D., Auer, M. and Ewald, AJ., 2016, “Twist1+ epithelial cells retain adhesive and proliferative capacity throughout dissemination,” Biol Open. pii: bio.019703. PMID: 27402962 PubMed

Nomura, M., Liu, J., Rovira, II., Gonzalez-Hurtado, E., Lee, J., Wolfgang, MJ., Finkel, T., 2016, “Fatty acid oxidation in macrophage polarization,” Nat Immunol.17(3):216-7. PMID: 26882249 PubMed

Ellison, D., Mugler, A., Brennan, MD., Lee, SH., Huebner, RJ., Shamir, ER., Woo, LA., Kim, J., Amar, P., Nemenman, I., Ewald, AJ. and Levchenko, A., 2016, “Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis,” Proc Natl Acad Sci U S A. 113(6):E679-88. PMID: 26792522 PubMed​

Mills, EW., Wangen, J., Green, R. and Ingolia, NT., 2016, “Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets,” Cell Rep. 17(1):1-10. PMID: 27681415 PubMed​

Hwang, J., Ribbens, D., Raychaudhuri, S., Cairns, L.Gu, H., Frost, A., Urban, S. and Espenshade, PJ., 2016, “A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP,” EMBO J. pii: e201693923. PMID: 27655872 PubMed

Freed, D. and Pevsner, J., 2016, “The Contribution of Mosaic Variants to Autism Spectrum Disorder,” PLoS Genet. 12(9):e1006245. doi: 10.1371/journal.pgen.1006245. PMID: 27632392 PubMed

Avin, BA., Umbricht, CB. and  Zeiger, MA., 2016, “Human telomerase reverse transcriptase regulation by DNA methylation, transcription factor binding and alternative splicing,” (Review), nt J Oncol. PMID: 27779655 PubMed

Tu-Sekine, B., Goldschmidt, HL. and Raben, DM., 2016, “DGK-θ: Structure, Enzymology, and Physiological Roles,” Front Cell Dev Biol. 4:101. PMCID:PMC5021689. PubMed

Pohlmeyer, CW., Walker-Sperling, VE., Blankson, JN., 2016, “What can we do to reduce the viral reservoir in HIV-1-infected individuals?,”Future Microbiol. 11:839-42. PMID: 27416850. PubMed

Hanlon, CD. and Andrew, DJ., 2016, “Drosophila FoxL1 non-autonomously coordinates organ placement during embryonic development,” Dev Biol. 419(2):273-284. PMCID: PMC5237845. PubMed

Cheung, KJ., Padmanaban, V., Silvestri, V., Schipper, K., Cohen, JD., Fairchild, AN., Gorin, MA., Verdone, JE., Pienta, KJ., Bader, JS. and Ewald, AJ., 2016, “Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters,” Proc Natl Acad Sci U S A. 113(7):E854-63.Epub 2016 Feb 1. PMID: 26831077 PubMed

Rodriguez, S., Lei, X., Petersen, PS., Tan, SY., Little, HC., Wong, GW., 2016, “Loss of CTRP1 disrupts glucose and lipid homeostasis,” Am J Physiol Endocrinol Metab. 23:ajpendo.00087.2016. PMID: 27555298 PubMed

Martin-Eauclaire, MF., Salvatierra, J., Bosmans, F. and Bougis, PE., 2016, “The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension,” FEBS Lett. PMID: 27528512 PubMed

Huebner, RJ., Neumann, NM., Ewald, AJ., 2016, “Mammary epithelial tubes elongate through MAPK-dependent coordination of cell migration,” Development. 143(6):983-93. PMID: 26839364 PubMed

Ma, Q., de Cuevas, M., Matunis, EL., “Chinmo is sufficient to induce male fate in somatic cells of the adult Drosophila ovary,” Development. 143(5):754-63. PMID: 26811385  PubMed

Moreno, A., Froehlig, JR., Bachas, S., Gunio, D., Alexander, T., Vanya, A. and Wade, H., 2016, “Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins,” Biochemistry. 55(34):4850-63. 18. PMID: 27505298 PubMed

Ferrandino, G., Nicola, JP., Sánchez, YE., Echeverria, I., Liu, Y., Amzel, LM. and Carrasco, N., 2016, “Na+ coordination at the Na2 site of the Na+/I- symporter,” Proc Natl Acad Sci U S A. pii: 201607231. PMID: 27562170 PubMed

Yuan, G., Peng, YJ., Khan, SA., Nanduri, J., Singh, A., Vasavda, C., Semenza, GL., Kumar, GK., Snyder, SH. and Prabhakar, NR., 2016, “H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea,” Sci Signal. 9(441):ra80. PMID: 27531649 PubMed

Laskey, SB., Pohlmeyer, CW., Bruner, KM. and Siliciano, RF., 2016, “Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality,”  PLoS Pathog. 12(8):e1005689. PMCID:PMC4975415 PubMed

Oh, Y., Cho, GS., Li, Z., Hong, I., Zhu, R., Kim, MJ., Kim, YJ., Tampakakis, E., Tung, L., Huganir, R., Dong, X., Kwon, C. and Lee, G., 2016, “Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons,” Cell Stem Cell. PMID: 27320040 PubMed

Lee, J., Choi, J., Scafidi, S. and Wolfgang, MJ., 2016, “Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation,” Cell Rep. 16(1):201-12. PMID: 27320917  PubMed

Cho, S., Dickey, SW., and Urban, S., 2016, “Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis,” Mol Cell. pii: S1097-2765(15)00978-8. PubMed

Campbell, DP., Chrysostomou, E. and Doetzlhofer, A., 2016, “Canonical Notch signaling plays an instructive role in auditory supporting cell development,” Sci Rep. 6:19484. PMCID: PMC472625 PubMed

Calzada, E., Onguka, O. and Claypool, SM., 2016, “Phosphatidylethanolamine Metabolism in Health and Disease,” Int Rev Cell Mol Biol. 321:29-88. PubMed

Ellison, D., Mugler, A., Brennan, MD., Lee, SH., Huebner, RJ., Shamir, ER., Woo, LA., Kim, J., Amar, P., Nemenman, I., Ewald, AJ. and Levchenko, A., 2016, “Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis,” Proc Natl Acad Sci U S A. pii: 201516503. PubMed

Goldschmidt, HL., Tu-Sekine, B., Volk, L., Anggono, V., Huganir, RL. and Raben, DM., 2016,  “DGKθ Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses,” Cell Rep. 14(2):200-7. PubMed

Mirsafian, H., Manda, SS., Mitchell, CJ., Sreenivasamurthy, S., Ripen, AM., Mohamad, SB., Merican, AF., and Pandey, A., 2016,  “Long non-coding RNA expression in human primary monocytes,” Genomics. pii: S0888-7543(16)30002-7. PubMed

Wasilewski, LN., El-Diwany, R., Munshaw, S., Snider, AE., Brady, JK., Osburn, WO., Ray, SC., and Bailey, JR., 2016, “A hepatitis C virus envelope polymorphism confers resistance to neutralization by polyclonal sera and broadly neutralizing monoclonal antibodies,” J Virol. pii: JVI.02837-15. PubMed

Pedersen, SM., Chan, W., Jattani, RP., Mackie, DS. and Pomerantz, JL., 2015, “Negative Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181,” Mol Cell Biol. pii: MCB.00876-15.  PubMed

Pedersen, SM., Chan, W., Jattani, RP., Mackie, DS., and Pomerantz, JL., 2016,  “Correction for Pedersen et al., Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181,” Mol Cell Biol. 36(8):1322.​​ PubMed

Jattani, RP., Tritapoe, JM., and Pomerantz, JL., 2016, “Intramolecular Interactions and Regulation of Cofactor Binding by the Four Repressive Elements in the Caspase Recruitment Domain-Containing Protein 11 (CARD11) Inhibitory Domain,” J Biol Chem. pii: jbc.M116.717322.​​PubMed

Lee, J., Choi, J., Aja, S., Scafidi, S., and Wolfgang, MJ., 2016, “Loss of Adipose Fatty Acid Oxidation Does Not Potentiate Obesity at Thermoneutrality,” Cell Rep. 14(6):1308-16.​ PMCID: PMC4758873 PubMed

Bachas, S., Kohr, B., and Wade, H., 2016, “Charge is Major Determinant of Activation of the Ligand-Responsive Multidrug Resistance Gene Regulator,” BmrR. C​hemMedChem. ​ PubMed

Shirley, MD., Frelin, L., López, JS., Jedlicka, A., Dziedzic, A., Frank-Crawford, MA., Silverman, W., Hagopian, L., and Pevsner, J., 2016, “Copy Number Variants Associated with 14 Cases of Self-Injurious Behavior,” PLoS One. 11(3):e0149646.​ ​ PubMed

Meier, EL., Razavi, S., Inoue, T., and Goley, ED., 2016, “A novel membrane anchor for FtsZ is linked to cell wall hydrolysis in Caulobacter crescentus,” Mol Microbiol.​ ​ PubMed

Salvatierra, J. and Bosmans, F., 2016, “A painful tale about synthetic scorpion toxins,” Channels (Austin). [Epub ahead of print]​ ​ PubMed​

Chamling, X., Sluch, VM., and Zack, DJ., 2016, “The Potential of Human Stem Cells for the Study and Treatment of Glaucoma,” Invest Ophthalmol Vis Sci. 57(5):ORSFi1-6.​ PubMed

Mitchell, CJ., Kim, MS., Zhong, J., Nirujogi, RS., Bose, AK., and Pandey, A., 2016, “Unbiased identification of substrates of protein tyrosine phosphatase ptp-3 in C. elegans,” Mol Oncol.  pii: S1574-7891(16)30010-2.​ PubMed​

Zitouni, S., Francia, ME., Leal, F., Montenegro Gouveia, S., Nabais, C., Duarte, P., Gilberto, S., Brito, D., Moyer, T., Kandels-Lewis, S., Ohta, M., Kitagawa, D., Holland, AJ., Karsenti, E., Lorca, T., Lince-Faria, M., Bettencourt-Dias, M., 2016, “CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis,”  Curr Biol. pii: S0960-9822(16)30300-1.​ PubMed

Lei, X., Rodriguez, S., Petersen, PS., Seldin, MM., Bowman, CE., Wolfgang, MJ., and Wong, GW., 2016, “Loss of CTRP5 improves insulin action and hepatic steatosis,” Am J Physiol Endocrinol Metab. ajpendo.00010.2016. PubMed

Bowman, CE., Zhao, L., Hartung, T., and Wolfgang, MJ., 2016, “Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series,” Mol Cell Biol. 36(15):2089-104. PMCID: PMC4946427 PubMed 

Lin, X., Steinberg, S., Kandasamy, SK., Afzal, J., Mbiyangandu, B., Liao, SE., Guan, Y., Corona-Villalobos, CP., Matkovich, SJ.,  Epstein, N., Tripodi, D., Huo, Z., Cutting, G., Abraham, TP., Fukunaga, R., and Abraham, MR., 2016, “Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis,” PLoS One. 11(5):e0156065. eCollection 2016.​  PubMed

Pokorná, L., Čermáková, P., Horváth, A., Baile, MG., Claypool, SM., Griač, P., Malínský, J. and Balážová, M., 2016, “Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and function,” Biochim Biophys Acta. 1857(1):34-45. PMCID: PMC4690203  PubMed

Mitchell, CJ., Kim, MS., Na, CH., and Pandey, A., 2016, ” PyQuant: a versatile framework for analysis of quantitative mass spectrometry data,” Mol Cell Proteomics. pii: mcp.O115.056879  15(8):2829-38. PMCID: PMC4974355  PubMed​

Lee, J., Choi, J., Wong, GW., and Wolfgang, MJ., 2016, “Neurometabolic roles of ApoE and Ldl-R in mouse brain,” J Bioenerg Biomembr. ​48(1):13-21. PMCID: PMC4733629  PubMed

2015

Maruotti, J., Sripathi, SR., Bharti, K., Fuller, J., Wahlin, KJ., Ranganathan, V., Sluch, VM., Berlinicke, CA., Davis, J., Kim, C., Zhao, L., Wan, J., Qian, J., Corneo, B., Temple, S., Dubey, R., Olenyuk, BZ., Bhutto, I., Lutty, GA., and Zack, DJ., 2015, “Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells,” Proc Natl Acad Sci U S A. 112(35):10950-5.​ PMCID: PMC4568212  PubMed

Lin, Q., Jia, B., Mitchell, LA., Luo, J., Yang, K., Zeller, KI., Zhang, W., Xu, Z., Stracquadanio, G., Bader, JS., Boeke, JD., and Yuan, YJ., 2015, “RADOM, an efficient in vivo method for assembling designed DNA fragments up to 10 kb long in Saccharomyces cerevisiae,” ACS Synth Biol. 4(3):213-20.​ PubMed

Clister, T., Mehta, S. and Zhang, J., 2015, “Single-cell Analysis of G-protein Signal Transduction,” J Biol Chem, 290(11):6681-8. PMCID: PMC4358091 PubMed

Greenspan, LJ., de Cuevas, M. and Matunis, E., 2015, “Genetics of Gonadal Stem Cell Renewal,” Annu Rev Cell Dev Biol,31:291-315  PMCID: PMC4659427 PubMed

Garcia-Gonzalo FR*, Phua SC*, Roberson EC, Garcia III G, Abedin M, Schurmans S, Inoue T, Reiter JF. 2015. Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Developmental Cell. 34: 400-409. (*co-first authors) PMCID: PMC4557815 PubMed

Phua, SC., Lin, YC. and Inoue, T., 2015, “An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli,” Cell Calcium, 58: 415-422, Review. PMCID: PMC4564334 [Available on 2016-10-01] PubMed

Koutmou, KS., Schuller, AP., Brunelle, JL., Radhakrishnan, A., Djuranovic, S. and Green, R., 2015, “Ribosomes slide on lysine-encoding homopolymeric A stretches,” Elife, 4: e05534. PMCID: PMC4363877 PubMed

Goodrich, AC. and Frueh, DP., 2015, “A Nuclear Magnetic Resonance Method for Probing Molecular Influences of Substrate Loading in Nonribosomal Peptide Synthetase Carrier Proteins. Biochemistry, 54, 1154-6.  PMCID: PMC4378656 PubMed

Lu, YW. and Claypool, SM., 2015, “Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes,” Front Genet. 2015 Feb 3;6:3 PMCID: PMC4315098

PubMed

Kowalinski, E., Schuller, A., Green, R. and Conti, E., 2015, “Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases,” Structure, 23(7):1336-43 PMCID: PMC4509514  PubMed

Sluch, VM., Davis, CH., Ranganathan, V., Kerr, JM., Krick, K., Martin, R., Berlinicke, CA., Marsh-Armstrong, N., Diamond, JS., Mao, HQ. and Zack, DJ., 2015, “Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line,” Sci Rep. 5:16595. PMCID: PMC4643248 PubMed

Cheng, YL. and Andrew, DJ., 2015, “Extracellular Mipp1 Activity Confers Migratory Advantage to Epithelial Cells during Collective Migration,” Cell Rep. 13(10):2174-88. PMCID: PMC4776642. PubMed

Goodrich, AC., Harden, BJ. and Frueh, DP., 2015, “Solution Structure of a Nonribosomal Peptide Synthetase Carrier Protein Loaded with Its Substrate Reveals Transient, Well-Defined Contacts,” J Am Chem Soc. PMID: 26334259​ PubMed

Sun, G. j, Zhou, Y., Ito, S., Bonaguidi, M. a, O’Brien, G. s, Kawasaki, N., Modak, N., Zhu, Y., Ming, G.-L., Song, H., “Latent tri-lineage potential of adult neural stem cells in the hippocampus revealed by Nf1 inactivation”, Nature Neuroscience, 2015 Dec;18(12):1722-4. PMID: 26523645 PubMed

Ward, MD. and Leahy, DJ., 2015, “Kinase activator-receiver preference in ErbB heterodimers is determined by intracellular regions and is not coupled to extracellular asymmetry,” J Biol Chem. 290(3):1570-9. PMCID: PMC4340403 PubMed

Deng, K., Pertea, M., Rongvaux, A., Wang, L., Durand, CM., Ghiaur, G., Lai, J., McHugh, HL., Hao, H., Zhang, H., Margolick, JB., Gurer, C., Murphy, AJ., Valenzuela, DM., Yancopoulos, GD., Deeks, SG., Strowig, T., Kumar, P., Siliciano, JD., Salzberg, SL., Flavell, RA., Shan, L. and Siliciano, RF, 2015, “Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations,” Nature.15;517(7534):381-5. PMCID: PMC4406054  PubMed

Multhaup, ML., Seldin, MM., Jaffe, AE., Lei, X., Kirchner, H., Mondal, P., Li, Y., Rodriguez, V., Drong, A., Hussain, M., Lindgren, C., McCarthy, M., Näslund, E., Zierath, JR., Wong, GW. and Feinberg, AP., 2015, “Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes,” Cell Metab. 21(1):138-49. PMCID: PMC4340475  PubMed

Dancy, BM. and Cole, PA., 2015, “Protein Lysine Acetylation by p300/CBP,” Chem Rev, 115(6):2419-52. PMCID: PMC4378506 PubMed

Goodrich, AC. and Frueh, DP., 2015, “A Nuclear Magnetic Resonance Method for Probing Molecular Influences of Substrate Loading in Nonribosomal Peptide Synthetase Carrier Proteins. Biochemistry, 54, 1154-6.  PMCID: PMC4378656 PubMed

Harr, JC.*, Luperchio, TR.*, Wong, X.*, Cohen, E*., Wheelan, SJ. and Reddy, KL., 2015, “Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins,” J Cell Biol. 208(1):33-52. PMCID: PMC4284222 *equal contribution.​ PubMed​

Surcel, A., Ng, WP., West-Foyle, H., Zhu, Q., Ren, Y., Avery, LB., Krenc, AK., Meyers, DJ., Rock, RS., Anders, RA., Freel, Meyers, CL. and Robinson, DN., 2015, “Pharmacological activation of myosin II paralogs to correct cell mechanics defects,” Proc Natl Acad Sci USA, 112(5):1428-33.  PMCID: PMC4321244 PubMed​

Clister, T., Mehta, S. and Zhang, J., 2015, “Single-cell Analysis of G-protein Signal Transduction,” J Biol Chem, 290(11):6681-8. PMCID: PMC4358091 PubMed

Koutmou, K.S., Schuller, A.P., Brunelle, J.L., Radhakrishnan, A., Djuranovic, S. & Green, R. Ribosomes slide on lysine-encoding homopolymeric A stretches. eLife, e05534 (2015). . PMCID: PMC4363877 PubMed​

Lu, YW. and Claypool, SM., 2015, “Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes,” Front Genet. 2015 Feb 3;6:3 PMCID: PMC4315098  PubMed​

Lei, X.*, Li, Q., Rodriguez, S.*, Tan, SY.*, Seldin, MM.*, McLenithan, JC., Jia, W. and Wong, GW., 2015, “Thromboxane synthase deficiency improves insulin action and attenuates adipose tissue fibrosis,” Am J Physiol Endocrinol Metab. 308(9):E792-804 *equal contribution PubMed

Cox, E., Uzoma, I., Guzzo, C., Jeong, JS., Matunis, M., Blackshaw, S. and Zhu, H., 2015, “Identification of SUMO E3 Ligase-Specific Substrates Using the HuProt Human Proteome Microarray,” Methods Mol Biol. 1295:455-63. PMCID: unknown PubMed

Zhou, X., Clister, TL., Lowry, PR., Seldin, MM., Wong, GW. and Zhang, J., 2015, “Dynamic Visualization of mTORC1 Activity in Living Cells,” Cell Rep. pii: S2211-1247(15)00177-1. PMCID: PMC4567530  PubMed

Eginton C, Cressman WJ, Bachas S, Wade H, Beckett D. Allosteric Coupling via Distant Disorder-to-Order Transitions. J Mol Biol. 2015 Apr 24;427(8):1695-1704. doi: 10.1016/j.jmb.2015.02.021. Epub 2015 Mar 4. PubMed

 

Deng, H., Wang, W., Yu, J., Zheng, Y., Qing, Y., and Pan, D., 2015, “Spectrin regulates Hippo signaling by modulating cortical actomyosin activity,”  ELife, 4:e06567.  PMCID: PMC4412106  PubMed

Yoo, SW., Motari, MG., Susuki, K., Prendergast, J., Mountney, A., Hurtado, A. and Schnaar, RL., 2015 “Sialylation regulates brain structure and function,” FASEB J. 29(7):3040-53. PMCID: PMC4478807 PubMed​

Metcalf, Pate, KA., Pohlmeyer, CW., Walker-Sperling, VE., Foote, JB., Najarro, KM., Cryer, CG., Salgado, M., Gama, L., Engle, EL., Shirk, EN., Queen, SE., Chioma, S., Vermillion, MS., Bullock, B., Li, M., Lyons, CE., Adams, RJ., Zink, MC., Clements, JE., Mankowski, JL. and Blankson, JN., 2015, “A murine viral outgrowth assay to detect residual HIV-1 in patients with undetectable viral loads,” J Infect Dis. 212:1387-1396. PMCID: PMC4601916 ​ PubMed

Onguka, O., Calzada, E., Ogunbona, OB. and Claypool, SM., 2015, “Phosphatidylserine Decarboxylase 1 Autocatalysis and Function Does Not Require a Mitochondrial-specific Factor,” J Biol Chem, 290: 12744-52  PMCID: PMC4432291  PubMed​

Li, Z., He, SQ., Tseng, PY., Xu, Q., Tiwari, V., Yang, F., Shu, B., Zhang, T., Tang, Z., Raja, SN., Wang, Y., Dong, X. and Guan, Y., 2015, “The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms,” Neuroscience, 300:393-403. PMCID: PMC4485588  PubMed​

Zhang, W., Wu, J., Ward, MD., Yang, S., Chuang, YA., Xiao, M., Li, R., Leahy, DJ. and Worley, PF., 2015, “Structural basis of arc binding to synaptic proteins: implications for cognitive disease.” Neuron. 22;86(2):490-500. PMCID: PMC4409568 PubMed

Kurbanov, F., Kim, Y., Latanich, R., Chaudhari, P., El-Diwany, R., Knabel, M., Kandathil, AJ., Cameron, A., Cox, A., Jang, YY., Thomas, DL. and Balagopal, A., 2015, “IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes,” Antivir Ther. doi: 10.3851/IMP2974. [Epub ahead of print]  PMCID: unknownPubMed

Hasan, S., Hétié, P amd Matunis, EL., 2015, “Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1,” Dev Biol, 404(1):27-39 PMCID: PMC4469572 PubMed

Westerbeck, JW. and Machamer, CE., 2015, “A Coronavirus E Protein is Present in Two Distinct Pools with Different Effects on Assembly and the Secretory Pathway,” J Virol., 89:18.  PMCID: PMC4542375  PubMed

Zhou, Y., Williams, J., Smallwood, PM. and Nathans, J., 2015, “Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina,” PLoS One. 10(12):e0143650.​ ​ PubMed

Lim, C., Gandhi, S., Biniossek, ML., Feng, L., Schilling, O., Urban, S., and Chen, X., 2015, “An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation,” Cell Rep. 13(2):315-25. PMCID: PMC4607668 PubMed

Subramanian, M., Timmerman, CK., Schwartz, J.L., Pham, DL. and Meffert, MK., 2015, “Characterizing autism spectrum disorders by key biochemical pathways,” Front Neurosci. 9:313.  Review. PMCID: PMC4586332 PubMed

Lambrus, BG., Uetake, Y., Clutario, KM., Daggubati, V., Snyder, M., Sluder, G. and Holland, AJ., 2015, “p53 protects against genome instability following centriole duplication failure,” J Cell Biol., 210(1):63-77. PMCID: PMC4494000  PubMed

Hobbs, RP., DePianto, DJ., Jacob, JT., Han, MC., Chung, BM., Batazzi, AS., Poll, BG., Guo, Y., Han, J., Ong, S., Zheng, W., Taube, JM., Čiháková, D., Wan, F. and Coulombe, PA. 2015, “Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes,” Nat Genet. 47(8):933-8. PMCID: PMC4520766 ​PubMed​

Moore,CD.*, Ajala, OZ.* and Zhu, H., 2015, “Applications in high-content functional protein microarrays,” Curr Opin Chem Biol. 30:21-27.  Review. *equal contribution PubMed

Echeverria, I., Liu, Y., Gabelli, SB., and Amzel, LM., 2015, “Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α,” FEBS J. 282(18):3528-42.​ PMCID: PMC4573839 PubMed

Margolis, SS., Sell, GL., Zbinden, MA., and Bird, LM., 2015, “Angelman Syndrome,” Neurotherapeutics. 12(3):641-50.​ ​ PubMed

Ellis, JM., Bowman, CE. and Wolfgang, MJ., 2015, “Metabolic and tissue-specific regulation of acyl-CoA metabolism,” PLoS One. 10(3):e0116587.​ ​ PubMed

Yuan, G.*, Vasavda, C.*, Peng, YJ.*, Makarenko, VV.*, Raghuraman, G., Nanduri, J., Gadalla, MM., Semenza, GL., Kumar, GK., Snyder, SH. and Prabhakar, NR., 2015, “Protein kinase G-regulated production of H2S governs oxygen sensing,” Sci Signal. 8(373):ra37. *equal contribution  PubMed​

Mohammad, F., Woolstenhulme, CJ., Green, R., and Buskirk, AR., 2015, “Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling,” Cell Rep. pii: S2211-1247(15)01529-6.​  PubMed

Metcalf Pate, KA., Pohlmeyer, CW., Walker-Sperling, VE., Foote, JB., Najarro, KM., Cryer, CG., Salgado, M., Gama, L., Engle, EL., Shirk, EN., Queen, SE., Chioma, S., Vermillion, MS., Bullock, B., Li, M., Lyons, CE., Adams, RJ., Zink, MC., Clements, JE., Mankowski, JL., and Blankson, JN., 2015, “A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads,” J Infect Dis. 212(9):1387-96. PubMed

de la Peña, AH., Suarez, A., Duong-Ly, KC., Schoeffield, AJ., Pizarro-Dupuy, MA., Zarr, M., Pineiro, SA., Amzel, LM. and Gabelli, SB., 2015, “Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus,” PLoS One, PMID: 26524597 PubMed

Baras, AS., Mitchell, CJ., Myers, JR., Gupta, S., Weng, LC., Ashton, JM., Cornish, TC., Pandey, A. and  Halushka, MK., 2015, “miRge – A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy,” PLoS One. PMID: 26571139  PubMed

Phua, SC., Lin, YC. and Inoue, T., 2015, “An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli,” Cell Calcium. 58(4):415-22. Review. PMID: 25828566 PubMed​

Lim, C., Gandhi, S., Biniossek, ML., Feng, L., Schilling, O., Urban, S., Chen, X., 2015, An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation. Cell Rep. 13(2):315-25. PMID: 26440886  PubMed

Sundararajan, K.*, Miguel, A., Desmarais, SM., Meier, EL*., Casey, Huang, K. and Goley, ED.*, 2015, “The bacterial tubulin FtsZ requires its intrinsically disordered linker to direct robust cell wall construction,” Nat Commun. 6:7281. PMCID: PMC4532373 *equal contribution​ PubMed

Kurbanov, F., Kim, Y., Latanich, R., Chaudhari, P., El-Diwany, R., Knabel, M., Kandathil, AJ., Cameron, A., Cox, A., Jang, YY., Thomas, DL. and Balagopal, A., 2015, “IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes,” Antivir Ther. doi: 10.3851/IMP2974. [Epub ahead of print]  PMCID: unknown PubMed

Greenspan, LJ., de Cuevas, M. and Matunis, E., 2015, “Genetics of gonadal stem cell renewal,” Annu Rev Cell Dev Biol. 31:291-315. PMID: 26355592 PubMed​

Lee, CF., Lo, YC., Cheng, CH., Furtmüller, GJ., Oh, B., Andrade-Oliveira, V., Thomas, AG., Bowman, CE., Slusher, BS., Wolfgang, MJ., Brandacher, G., Powell, JD., 2015, “Preventing Allograft Rejection by Targeting Immune Metabolism,” Cell Rep. 13(4):760-70. PMID: 26489460 PubMed

Mitchell, CJ., Getnet, D., Kim, MS., Manda, SS., Kumar, P., Huang, TC., Pinto, SM., Nirujogi, RS., Iwasaki, M., Shaw, PG., Wu, X., Zhong, J., Chaerkady, R., Marimuthu, A., Muthusamy, B., Sahasrabuddhe, NA., Raju, R., Bowman, C., Danilova, L., Cutler, J., Kelkar, DS., Drake, CG., Prasad, TS., Marchionni, L., Murakami, PN., Scott, AF., Shi, L., Thierry-Mieg, J., Thierry-Mieg, D., Irizarry, R., Cope, L., Ishihama, Y., Wang, C., Gowda, H. and Pandey, A., 2015, “A multi-omic analysis of human naïve CD4+ T cells,” BMC Syst Biol. 9:75. PMID: 26542228 PubMed

2014

Goodrich, A.C., Nichols, S.R., and Frueh, D.P, 2014, “Resonance Assignments and Structure Determination of Large and Challenging Proteins,” Encyclopedia of Magnetic Resonance. 3. 

Zhang, H., Zou, B., Du, F., Xu, K. and Li, M., 2014, “Reporting Sodium Channel Activity using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5,” Mol Pharmacol.87(2):207-17  PMCID: PMC4293450 PubMed

Van den Elzen, A.M.G., Schuller, A., Green, R. and Séraphin, B., 2014, “Dom34-Hbs1 mediated dissociation of inactive 80S ribosomes promotes restart of translation after stress.,” EMBO J. 33, 265-276 (2014). PMCID: PMC3989619 ​PubMed

Davis, C.-H.O., Kim, K.-Y., Bushong, E. a, Mills, E. a, Boassa, D., Shih, T., Kinebuchi, M., Phan, S., Zhou, Y., Bihlmeyer, N. a, Nguyen, J.V., Jin, Y., Ellisman, M.H., Marsh-Armstrong, N., “Transcellular degradation of axonal mitochondria”, Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9633-8. PMID: 24979790 PubMed

Wang, JT. and Seydoux, G., 2014, “P granules,” Curr Biol. 24(14):R637-8. PubMed

Schaughency, P., Merran, J., and Corden, JL., 2014, “Genome-wide mapping of yeast RNA polymerase II termination,” PLoS Genet. 10(10):e1004632.​ PubMed

Bruner, JK., Zou, B., Zhang, H., Zhang, Y., Schmidt, K. and Li, M., 2014, “Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel,” Eur J Pharmacol. pii: S0014-2999(14)00463-4. PubMed

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Baile, MG., Lu, YW. and Claypool, SM., 2014, “The topology and regulation of cardiolipin biosynthesis and remodeling in yeast,” Chem Phys Lipids, 179:25-31. PMCID: PMC3947685   PubMed

Wang, Y., Wang, JT., Rasoloson, D., Stitzel, ML., O’Connell, KF., Smith, HE. and Seydoux, G., 2014, “Identification of Suppressors of mbk-2/DYRK by Whole-Genome Sequencing,” G3 (Bethesda), 4(2):231-41.  PMCID: PMC3931558  PubMed

Hétié, P., de Cuevas, M. and Matunis, E., 2014, “Conversion of quiescent niche cells to somatic stem cells causes ectopic niche formation in the Drosophila testis,” Cell Rep. 7(3):715-21. PMCID: PMC4080611​ PubMed

Shamir, ER. and Ewald, AJ., 2014, “Three-dimensional organotypic culture: experimental models of mammalian biology and disease,” Nat Rev Mol Cell Biol. 15(10):647-64. PMCID: PMC4352326 PubMed

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Herb, BR., 2014, “Epigenetics as an answer to Darwin’s “special difficulty”,” Front Genet. 5:321. PMCID: PMC4162389 PubMed

Chen, BC., Legant, WR., Wang, K., Shao, L., Milkie, DE., Davidson, MW., Janetopoulos, C., Wu, XS., Hammer, JA. 3rd, Liu, Z., English, BP., Mimori-Kiyosue, Y., Romero, DP., Ritter, AT., Lippincott-Schwartz, J., Fritz-Laylin, L., Mullins, RD., Mitchell, DM., Bembenek, JN., Reymann, AC., Böhme, R., Grill, SW., Wang, JT., Seydoux, G., Tulu, US., Kiehart, DP. and Betzig, E., 2014, “Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution,” Science. 346(6208):1257998. PMCID: PMC4336192 PubMed​

Hua, ZL., Jeon, S., Caterina, MJ. and Nathans, J., 2014, “Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system,” Proc Natl Acad Sci U S A. 111(29):E3005-14.  PMCID: PMC4115534​ PubMed

Ren, Y., West-Foyle, H., Surcel, A., Miller, C. and Robinson, DN., 2014, “Genetic suppression of a phosphomimic myosin II identifies system-level factors that promote myosin II cleavage furrow accumulation,” Mol Biol Cell. 25(25):4150-65.  PMCID: PMC4263456  PubMed

Salgado, M., Gandhi, S., Buckheit, RW., Berkenblit, GV. and Blankson, JN., 2014, “Evolution of an attenuated HIV-1 isolate in an elite suppressor,” AIDS Res Hum Retroviruses. 30(3):284-8. Epub 2013 Nov 13. PubMed

Cox, PM. and Bumpus, NN., 2014, “Structure-Activity Studies Reveal the Oxazinone Ring Is a Determinant of Cytochrome P450 2B6 Activity Toward Efavirenz,” ACS Med Chem Lett. 5(10):1156-1161. PMCID: PMC4191608 PubMed​

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Kalia, J., Milescu, M., Salvatierra, J., Wagner, J., Klint, JK., King, GF., Olivera, BM. and Bosmans, F., 2014, “From Foe to Friend: Using Animal Toxins to Investigate Ion Channel Function,” J Mol Biol. 427(1):158-75, Review. PMCID: PMC4277912 PubMed

Salvatierra, J., Lee, DA., Zibetti, C., Duran-Moreno, M., Yoo, S., Newman, EA., Wang, H., Bedont, JL., de Melo, J., Miranda-Angulo, AL., Gil-Perotin, S., Garcia-Verdugo, JM. and Blackshaw, S., 2014, “The LIM Homeodomain Factor Lhx2 Is Required for Hypothalamic Tanycyte Specification and Differentiation,” J Neurosci. 34(50):16809-20. PMCID: PMC4261103 PubMed​

Bende, NS., Dziemborowicz, S., Mobli, M., Herzig, V., Gilchrist, J., Wagner, J., Nicholson, GM., King, GF. and Bosmans, F., 2014, “A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a,” Nat Commun. 5:4350. PMCID: PMC4115291 PubMed

Stine, RR., Greenspan, LJ., Ramachandran, KV. and Matunis, EL., 2014, “Coordinate Regulation of Stem Cell Competition by Slit-Robo and JAK-STAT Signaling in the Drosophila Testis,” PLoS Genet. 10(11):e1004713. PMCID: PMC4222695  PubMed

Cleveland, TE 4th., McCabe, JM. and Leahy, DJ., 2014, “Detergent-solubilized Patched purified from Sf9 cells fails to interact strongly with cognate Hedgehog or Ihog homologs,” Protein Expr Purif, 104C, 92-102. PMCID: PMC4380871 PubMed

McCabe, JM. and Leahy, DJ., 2014, “Smoothened Goes Molecular: New Pieces in the Hedgehog Signaling Puzzle.” J Biol Chem, 6: 3500-7 PMCID: PMC4319017 PubMed​

Kelkar, DS., Provost, E., Chaerkady, R., Muthusamy, B., Manda, SS., Subbannayya, T., Selvan, LD., Wang, CH., Datta, KK., Woo, S., Dwivedi, SB., Renuse, S., Getnet, D., Huang, TC., Kim, MS.,, Pinto, SM., Mitchell, CJ., Madugundu, AK., Kumar, P., Sharma, J., Advani, J., Dey, G., Balakrishnan, L., Syed, N., Nanjappa, V., Subbannayya, Y., Goel, R., Keshava Prasad, TS., Bafna, V., Sirdeshmukh, R., Gowda, H., Wang, C., Leach, SD. and Pandey, A., 2014, “Annotation of the Zebrafish Genome through an Integrated Transcriptomic and Proteomic Analysis,” Mol Cell Proteomics. 13(11):3184-98. PMCID: PMC4223501 PubMed

Qing, Y., Yin, F., Wang, W., Zheng, Y., Guo, P., Schozer, F., Deng, H., and Pan, D., 2014, “The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6,” Elife, 3.  PMCID: PMC4118621   PubMed

Mehta, S., Aye-Han, NN., Ganesan, A., Oldach, L., Gorshkov, K. and Zhang, J., 2014, “Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin,” Elife. 3:e03765. PMCID: PMC4141273 PubMed

Berk, JM., Simon, DN., Jenkins-Houk, CR., Westerbeck, JW., Grønning-Wang, LM., Carlson, CR. and Wilson, KL., 2014, “The molecular basis of emerin-emerin and emerin-BAF interactions,” J Cell Sci. 127(Pt 18):3956-69. PMCID: PMC4163644 PubMed

Zhou, Y. and Nathans, J., 2014, “Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling,” Dev Cell. 31(2):248-56. PMCID: PMC4223636  PubMed

Rattner, A., Wang, Y., Zhou, Y., Williams, J. and Nathans, JH., 2014, “The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling,” Invest Ophthalmol Vis Sci. 55(12):8614-25. PMCID: PMC4280883  PubMed

Wang, J. T., Smith, J., Chen, B.-C., Schmidt, H., Rasoloson, D., Paix, A., Lambrus, BG., Calidas, D., Betzig, E., and Seydoux, G., 2014, “Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically-disordered proteins in C. elegans,” eLife, 3: e04591. PMCID: PMC4296509 PubMed

Heydarian, M., Luperchio, TR., Cutler, J., Mitchell, CJ., Kim, M., Pandey, A., Sollner-Webb, B. and Reddy, K., 2014, “Prediction of Gene Activity in Early B Cell Development Based on an Integrative Multi-Omics Analysis,” J Proteomics Bioinform. 7. pii: 1000302. PMCID: PMC4276347 PubMed

Ma, Q., Wawersik, M. and Matunis, EL., 2014, “The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche,” Dev Cell, 31(4):474-86. PMCID: PMC4254588  PubMed​

Tu-Sekine, B., Goldschmidt, H. and Raben, DM., 2014, “Diacylglycerol, phosphatidic acid, and their metabolic enzymes in synaptic vesicle recycling,” Adv Biol Regul, 57:147-52. PubMed

Lu, C., Ward, A., Bettridge, J., Liu, Y. and Desiderio, S., 2014, “An Autoregulatory Mechanism Imposes Allosteric Control on the V(D)J Recombinase by Histone H3 Methylation,” Cell Rep.10(1):29-38 PMCID: PMC4308961 PubMed

Freed, D., Stevens, EL. and Pevsner, J., 2014, “Somatic mosaicism in the human genome,” Genes (Basel). 5(4):1064-94. Review. PMCID: PMC4276927 PubMed

  • Lee J, Ellis JM, Wolfgang MJ. Adipose Fatty Acid Oxidation Is Required for Thermogenesis and Potentiates Oxidative Stress-Induced Inflammation. Cell Rep. 2015 Jan 7. pii: S2211-1247(14)01052-3. doi: 10.1016/j.celrep.2014.12.023. [Epub ahead of print] PubMed​

Suarez, A., Ueno, T., Huebner, R., McCaffery, JM. and Inoue, T., 2014, “Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells,” Sci Rep. 4:4693.   PubMed

Cross, BM., Breitwieser, GE., Reinhardt, TA. and Rao, R., 2014, “Cellular calcium dynamics in lactation and breast cancer: from physiology to pathology,” Am J Physiol Cell Physiol. 306(6):C515-26. PMCID: PMC3948975 PubMed​

Wong, X., Luperchio, TR. and Reddy, KL., 2014, “NET gains and losses: the role of changing nuclear envelope proteomes in genome regulation,” Curr Opin Cell Biol. 28C:105-120.  Review.​ PubMed

Colis, L., Peltonen, K., Sirajuddin, P., Liu, H., Sanders, S., Ernst, G., Barrow, JC. and Laiho, M., 2014, “DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response,” Oncotarget, 5(12):4361-4369. PMCID: PMC4147329 PubMed

Davis, CH., Kim, KY., Bushong, EA., Mills, EA., Boassa, D., Shih, T., Kinebuchi, M., Phan, S., Zhou, Y., Bihlmeyer, NA., Nguyen, JV., Jin, Y., Ellisman, MH. and Marsh-Armstrong, N., 2014, “Transcellular degradation of axonal mitochondria,” Proc Natl Acad Sci U S A. 111(26):9633-8.  PMCID: PMC4084443 PubMed

Guzzo, CM., Ringel, A., Cox, E., Uzoma, I., Zhu, H., Blackshaw, S., Wolberger, C. and Matunis, MJ., 2014, “Characterization of the SUMO-Binding Activity of the Myeloproliferative and Mental Retardation (MYM)-Type Zinc Fingers in ZNF261 and ZNF198,” PLoS One. 9(8):e105271. PMCID: PMC4136804​ PubMed

Kuang, Z., Cai, L., Zhang, X., Ji, H., Tu, BP. and Boeke, JD., 2014, “High-temporal-resolution view of transcription and chromatin states across distinct metabolic states in budding yeast,” Nat Struct Mol Biol. 21(10):854-63  PMCID: PMC4190017 ​ PubMed

Papazyan, R., Voronina, E., Chapman, JR., Luperchio, TR., Gilbert, TM., Meier, E., Mackintosh, SG., Shabanowitz, J., Tackett, AJ., Reddy, KL., Coyne, RS., Hunt, DF., Liu, Y. and Taverna, SD., 2014, “Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis,” Elife. 3:e02996. PMCID: PMC4141274 PubMed

Cieniewicz, AM., Moreland, L., Ringel, AE., Mackintosh, SG., Raman, A., Gilbert, TM., Wolberger, C., Tackett, AJ. and Taverna, SD., 2014, “The bromodomain of Gcn5 regulates site-specificity of lysine acetylation on histone H3,” Mol Cell Proteomics,13(11):2896-910.  PMCID: PMC4223480 PubMed

Gilbert, TM., McDaniel, SL., Byrum, SD., Cades, JA., Dancy, BC., Wade, H., Tackett, AJ., Strahl, BD. and Taverna, SD., 2014, “An H3K36me3 binding PWWP protein targets the NuA3 acetyltransferase complex to coordinate transcriptional elongation at coding regions,” Mol Cell Proteomics, 13(11):2883-95. PMCID: PMC4223479​ PubMed

Li, Y., Ma, Q., Cherry, CM. and Matunis, EL., 2014, “Steroid signaling promotes stem cell maintenance in the Drosophila testis,” Dev Biol. 394(1):129-41.  PMCID: PMC4165524​ PubMed

Kim, YS., Chu, Y., Han, L., Li, M., Li, Z., Lavinka, PC., Sun, S., Tang, Z., Park, K., Caterina, MJ., Ren, K., Dubner, R., Wei, F. and Dong, X., 2014, “Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain,” Neuron, 81(4):873-87.  PMCID: PMC3943838 PubMed

Debeljak, M., Freed, DN., Welch, JA., Haley, L., Beierl, K., Iglehart, BS., Pallavajjala, A., Gocke, CD., Leffell, MS., Lin, MT., Pevsner, J., Wheelan, SJ and Eshleman, JR., 2014, “Haplotype counting by next-generation sequencing for ultrasensitive human DNA detection,” J Mol Diagn. 16(5):495-503.      PubMed 

Colis, L., Ernst, G., Sanders, S., Liu, H., Sirajuddin, P., Peltonen, K., DePasquale, M., Barrow, JC. and Laiho, M., 2014, “Design, synthesis, and structure-activity relationships of pyridoquinazolinecarboxamides as RNA polymerase I inhibitors,” J Med Chem 57(11):4950-61.​ PMCID: PMC4059246​ PubMed 

Prendergast, J., Umanah, GK., Yoo, SW., Lagerlöf, O., Motari, MG., Cole, RN., Huganir, RL., Dawson, TM., Dawson, VL. and Schnaar, RL., 2014, “Ganglioside regulation of AMPA receptor trafficking,” J Neurosci. 34(39):13246-58. PMCID: PMC4172811  PubMed

Paix, A., Wang, Y., Smith, H., Lee, CY., Calidas, D., Lu, T., Smith, J., Schmidt, H., Krause, M. and Seydoux, G., 2014, “Scalable and Versatile Genome Editing Using Linear DNAs with Micro-homology to Cas9 Sites in Caenorhabditis elegans,” Genetics, 198(4):1347-56.  PMCID: PMC4256755 PubMed

Li, Z., He, SQ., Xu, Q., Yang, F., Tiwari, V., Liu, Q., Tang, Z., Han, L., Chu, YX., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Guan, X., Wei, F., Raja, SN., Dong, X. and Guan, Y., 2014, “Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice,” Pain, 155(8):1613-21. PMCID: PMC4104261  PubMed

Gilbert, CE., Zuckerman, DM., Currier, PL. and Machamer, CE., 2014, “Three basic residues of intracellular loop 3 of the Beta-1 adrenergic receptor are required for golgin-160-dependent trafficking,” Int J Mol Sci. 15(2):2929-45. PMCID: PMC3958891 PubMed

Brubaker, SW., Gauthier, AE., Mills, EW., Ingolia, NT. and Kagan, JC.,  2014, “A Bicistronic MAVS Transcript Highlights a Class of Truncated Variants in Antiviral Immunity,” Cell. 2014 Feb 13;156(4):800-11. doi: 10.1016/j.cell.2014.01.021. PMCID: PMC3959641 PubMed

Meier, EL. and Goley, ED., 2014, “Form and function of the bacterial cytokinetic ring,” Curr Opin Cell Biol. 26C:19-27.  PubMed

Oldach, L. and Zhang, J., 2014, “Genetically Encoded Fluorescent Biosensors for Live-Cell Visualization of Protein Phosphorylation,” Chem Biol. 21(2):186-197. PMCID: PMC4050661  PubMed

Luperchio, TR., Wong, X. and Reddy, KL., 2014, “Genome regulation at the peripheral zone: lamina associated domains in development and disease,” Curr Opin Genet Dev. 25C:50-61.  Review. PubMed

Huebner, RJ. and Ewald, AJ., 2014, “Cellular foundations of mammary tubulogenesis,” Semin Cell Dev Biol, 31:124-31. Review.​ PMCID: PMC4116098 PubMed

Annaluru, N., Muller, H., Mitchell, LA., Ramalingam, S., Stracquadanio, G., Richardson, SM., Dymond, JS., Kuang, Z., Scheifele, LZ., Cooper, EM., Cai, Y., Zeller, K., Agmon, N., Han, JS., Hadjithomas, M., Tullman, J., Caravelli, K., Cirelli, K., Guo, Z., London, V., Yeluru, A., Murugan, S., Kandavelou, K., Agier, N., Fischer, G., Yang, K., Martin, JA., Bilgel, M., Bohutski, P., Boulier, KM., Capaldo, BJ., Chang, J., Charoen, K., Choi, WJ., Deng, P., DiCarlo, JE., Doong, J., Dunn, J., Feinberg, JI., Fernandez, C., Floria, CE., Gladowski, D., Hadidi, P., Ishizuka, I., Jabbari, J., Lau, CY., Lee, PA., Li, S., Lin, D., Linder, ME., Ling, J., Liu, J., Liu, J., London, M., Ma, H., Mao, J., McDade, JE., McMillan, A., Moore, AM., Oh, WC., Ouyang, Y., Patel, R., Paul, M., Paulsen, LC., Qiu, J., Rhee, A., Rubashkin, MG., Soh, IY., Sotuyo, NE., Srinivas, V., Suarez, A., Wong, A., Wong, R., Xie, WR., Xu, Y., Yu, AT., Koszul, R., Bader, JS., Boeke, JD. and Chandrasegaran, S., 2014, “Total synthesis of a functional designer eukaryotic chromosome,” Science. 344(6179):55-8. . Erratum in: Science. 2014 May 23;344(6186):816. PMCID: PMC4033833 PubMed

Hodge, DL., Berthet, C., Coppola, V., Kastenmüller, W., Buschman, MD., Schaughency, PM., Shirota, H., Scarzello, AJ., Subleski, JJ., Anver, MR., Ortaldo, JR., Lin, F., Reynolds, DA., Sanford, ME., Kaldis, P., Tessarollo, L., Klinman, DM. and Young, HA., 2014, “IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice,” J Autoimmun. 53:33-45. PMCID: PMC4148478 PubMed

Shamir, ER., Pappalardo, E., Jorgens, DM., Coutinho, K., Tsai, WT., Aziz, K., Auer, M., Tran, PT., Bader, JS. and Ewald, AJ., 2014, “Twist1-induced dissemination preserves epithelial identity and requires E-cadherin,” J Cell Biol. 204(5):839-56. PMCID: PMC3941052 PubMed

Sluch, VM. and Zack, DJ. 2014, “Stem cells, retinal ganglion cells and glaucoma,” Dev Ophthalmol. 53:111-21. PMCID: PMC4547935  PubMed

Kim, MS., Pinto, SM., Getnet, D., Nirujogi, RS., Manda, SS., Chaerkady, R., Madugundu, AK., Kelkar, DS., Isserlin, R., Jain, S., Thomas, JK., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, NA., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, LD., Patil, AH., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, SK., Marimuthu, A., Sathe, GJ., Chavan, S., Datta, KK., Subbannayya, Y., Sahu, A., Yelamanchi, SD., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, KR., Syed, N., Goel, R., Khan, AA., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, TC., Zhong, J., Wu, X., Shaw, PG., Freed, D., Zahari, MS., Mukherjee, KK., Shankar, S., Mahadevan, A., Lam, H., Mitchell, CJ., Shankar, SK., Satishchandra, P., Schroeder, JT., Sirdeshmukh, R., Maitra, A., Leach, SD., Drake, CG., Halushka, MK., Prasad, TS., Hruban, RH., Kerr, CL., Bader, GD., Iacobuzio-Donahue, CA., Gowda, H. and Pandey, A., 2014, “A draft map of the human proteome, “Nature. 509(7502):575-81. PMCID: PMC4403737 PubMed

Chivukula, RR., Shi, G., Acharya, A., Mills, EW., Zeitels, LR., Anandam, JL., Abdelnaby, AA., Balch, GC., Mansour, JC., Yopp, AC., Maitra, A. and Mendell, JT., 2014, “An Essential Mesenchymal Function for miR-143/145 in Intestinal Epithelial Regeneration,” Cell.157(5):1104-16. PMCID: PMC4175516​ PubMed

Salgado, M., Swanson, MD., Pohlmeyer, CW., Buckheit, RW 3rd., Wu, J., Archin, NM., Williams, TM., Margolis, DM., Siliciano, RF., Garcia, JV. and Blankson,  JN., 2014, “HLA-B*57 Elite Suppressor and Chronic Progressor HIV-1 Isolates Replicate Vigorously and Cause CD4+ T cell Depletion in Humanized BLT Mice,” J Virol. 88:3340-3352  PMCID: PMC3957943 PubMed

2013

He, SQ., Han, L., Li, Z., Xu, Q., Tiwari, V., Yang, F., Guan, X., Wang, Y., Raja, SN., Dong, X. and Guan, Y., 2013, “Temporal changes in MrgC expression after spinal nerve injury,” Neuroscience. pii: S0306-4522(13)01065-8. PMCID: PMC3945476 

Lin, YC., Phua, SC., Lin, B. and Inoue, T.,  2013, “Visualizing molecular diffusion through passive permeability barriers in cells: conventional and novel approaches,” Curr Opin Chem Biol. 17(4):663-71. Review. PMCID: PMC3860267 PubMed

Su, S., Phua, SC., DeRos,e R., Chiba, S., Narita, K., Kalugin, PN., Katada, T., Kontani, K., Takeda, S. and Inoue, T., 2013, “Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia,” Nat Methods. 10(11):1105-7. PMCID: PMC3860264 PubMed

Patenaude, C., Zhang, Y., Cormack, B., Koehler, J. and Rao, R., 2013, “Essential Role for Vacuolar Acidification in Candida albicans Virulence,” J Biol Chem. 288(36):26256-64.  PMCID: PMC3764829PubMed

Frueh, DP., Goodrich, AC., Mishra, SH. and Nichols, SR., 2013, “NMR methods for structural studies of large monomeric and multimeric proteins,” Curr Opin Struct Biol., 23, 734-9. PMCID: PMC3805735PubMed

Eyler, DE., Wehner, KA. and Green, R., 2013, “Eukaryotic release factor 3 is required for multiple turnovers of peptide release catalysis by eukaryotic release factor 1,” J Biol Chem., 288(41):29530-8. PMCID: PMC3795251  PubMed

Yu, H., Lin, Z., Mattmann, ME., Zou, B., Terrenoire, C., Zhang, H., Wu, M., McManus, OB., Kass, RS., Lindsley, CW., Hopkins, CR. and Li, M., 2013, “Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels,” Proc Natl Acad Sci U S A. 110(21):8732-7. PMCID: PMC3666726 PubMed

Shirley, MD, 2013, “Concerns regarding “Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA”, Genomics. 102(4):430.  PubMed

Tu-Sekine, B., Goldschmidt, H., Petro, E. and Raben, DM., 2013, “Diacylglycerol kinase θ: regulation and stability,” Adv Biol Regul. 53(1):118-26. PMCID: PMC3992713PubMed

Berk, JM., Tifft, KE. and Wilson, KL., 2013, “The nuclear envelope LEM-domain protein emerin,” Nucleus, 4(4):298-314. PMCID: PMC3810338  PubMed

Hu, S., Wan, J., Su, Y., Song, Q., Zeng, Y., Nguyen, HN., Shin, J., Cox, E., Rho, HS., Woodard, C., Xia, S., Liu, S., Lyu, H., Ming, GL., Wade, H., Song, H., Qian, J. and Zhu, H., 2013, “DNA methylation presents distinct binding sites for human transcription factors,” Elife. 2:e00726. PMCID: PMC3762332 PubMed​

Wang, Z., Raines, LL., Hooy, RM., Roberson, H., Leahy, DJ. and Cole, PA., 2013, “Tyrosine Phosphorylation of Mig6 Reduces Its Inhibition of the Epidermal Growth Factor Receptor,” ACS Chem Biol. 8(11):2372-6. PMCID: PMC3830645PubMed

Lessard, JC., 2013, “Growth Media for E. coli,” Methods Enzymol. 533:181-9. PMID: 24182923  PubMed

Donnelly, CJ., Zhang, PW., Pham, JT., Heusler, AR., Mistry, NA., Vidensky, S., Daley, EL., Poth, EM., Hoover, B., Fines, DM., Maragakis, N., Tienari, PJ., Petrucelli, L., Traynor, BJ., Wang, J., Rigo, F., Bennett, CF., Blackshaw, S., Sattler, R. and Rothstein, JD., 2013, “RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention,” Neuron. ;80(2):415-28. PMCID: PMC4098943 PubMed

Salgado, M., Buckheit, R., Gandhi, S., Berkenblit, G., Blankson, J., 2013, “Evolution of an Attenuated HIV-1 Isolate in an Elite Suppressor,” AIDS Res Hum Retroviruses. PubMed

Lessard, JC., Piña-Paz, S., Rotty, JD., Hickerson, RP., Kaspar, RL., Balmain, A. and Coulombe, PA., 2013, “Keratin 16 regulates innate immunity in response to epidermal barrier breach,” Proc Natl Acad Sci USA, 110(48):19537-42. PMCID: PMC3845144 PubMed

Abrams, EW., Cheng, YL. and Andrew, DJ., 2013, “Drosophila KDEL Receptor Function in the Embryonic Salivary Gland and Epidermis,” PLoS One. 2013 Oct 18;8(10):e77618. PMCID: PMC3799842 PubMed

Teng, X., Dayhoff-Brannigan, M., Cheng, WC., Gilbert, CE., Sing, CN., Diny, N.L., Wheelan, SJ., Dunham, MJ., Boeke, JD., Pineda, FJ. and Hardwick, JM., 2013, “Genome-wide Consequences of Deleting Any Single Gene,” Mol Cell. 52(4):485-94. PMCID: PMC3975072     PubMed

Rath, P., Lal, B., Ajala, O., Li, Y., Xia, S., Kim, J. and Laterra, J., 2013, “In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells,” Transl Oncol. 6(2):104-11. Epub 2013 Apr 1. PMCID: PMC3612837      PubMed

Ruch, TR. and Machamer, CE., 2012, “The coronavirus E protein: assembly and beyond,” Viruses, 4(3):363-82. PMCID: PMC3347032 Pubmed 

Baile, MG. and Claypool, SM., 2013, “The power of yeast to model diseases of the powerhouse of the cell,” Front Biosci (Landmark Ed). 18:241-78. Review, PMCID: PMC3874933 PubMed

Zhang, F., Bhat, S., Gabelli, SB., Chen, X., Miller, MS., Nacev, BA., Cheng, YL., Meyers, DJ., Tenney, K., Shim, JS., Crews, P., Amzel, LM., Ma, D. and Liu, JO., 2013, “Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells,” J Med Chem. 56(10):3996-4016. PMCID: PMC3714011. PubMed

Cross, BM., Hack, A., Reinhardt, TA. and Rao, R., 2013, “SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation,” PLoS One. ;8(6):e67348. PMCID: PMC3696057 PubMed

Whited, K., Baile, MG., Currier, P. and Claypool, SM., 2013, “Seven functional classes of Barth syndrome mutation,” Hum Mol Genet. 1;22(3):483-92. PMCID: PMC3606006 PubMed

2012

Issigonis, M. and Matunis, E., 2012, “The Drosophila BCL6 homolog Ken and Barbie promotes somatic stem cell self-renewal in the testis niche,” Dev Biol. 368(2):181-92. PMCID: PMC3402624 Pubmed

Huster, D., Kühne, A., Bhattacharjee, A., Raines, L., Jantsch, V., Noe, J., Schirrmeister, W., Sommerer, I., Sabri, O., Berr, F., Mössner, J., Stieger, B., Caca, K. and Lutsenko, S., 2012, “Diverse functional properties of Wilson disease ATP7B variants,” Gastroenterology. 142(4), 947-956. PMCID: PMC3461965 Pubmed 

Hobbs, RP., Lessard, JC. and Coulombe, PA., 2012, “Keratin intermediate filament proteins – novel regulators of inflammation and immunity in skin,” J Cell Sci.,125(Pt 22):5257-8. PMCID: PMC3561851 Pubmed

Clayton, AM., Cirimotich, CM., Dong, Y. and Dimopoulos, G., 2013, “Caudal is a negative regulator of the Anopheles IMD pathway that controls resistance to Plasmodium falciparum infection,” Dev Comp Immunol. 39(4):323-32. PMCID: PMC3892953 Pubmed

Tamura, Y., Onguka, O., Itoh, K., Endo, T., Iijima, M., Claypool, SM. and Sesaki, H., 2012, “Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P,” J Biol Chem. 287(52):43961-71. PMCID: PMC3527979 Pubmed 

Stevens, EL., Baugher, JD., Shirley, MD., Frelin, LP. and Pevsner, J., 2012, “Unexpected relationships and inbreeding in HapMap phase III populations,” PLoS One. 7(11):e49575. PMCID: PMC3501496 Pubmed

Han, L., Ma, C., Liu, Q., Weng, HJ., Cui, Y., Tang, Z., Kim, Y., Nie, H., Qu, L., Patel, KN., Li, Z., McNeil, B., He, S., Guan, Y., Xiao, B., Lamotte, RH. and Dong, X., 2013, “A subpopulation of nociceptors specifically linked to itch,” Nat Neurosci.16(2):174-82. PMCID: PMC3557753 Pubmed 

Wang, Y., Rattner, A., Zhou, Y., Williams, J., Smallwood, PM. and Nathans, J., 2012, “Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity,” Cell. 151(6):1332-44, PMCID: PMC3535266  Pubmed 

Porter, JR., Burg, JS., Espenshade, PJ. and Iglesias, PA., 2012, “Identifying a static nonlinear structure in a biological system using noisy, sparse data,” J Theor Biol. 300:232-41. PMCID: PMC3307847  Pubmed 

Phua, SC., Pohlmeyer, C. and Inoue, T., 2012, “Rapidly relocating molecules between organelles to manipulate small GTPase activity,” ACS Chem Biol. 7(12):1950-5. PMCID: PMC3528809 PubMed

Mularoni, L., Zhou, Y., Bowen, T., Gangadharan, S., Wheelan, SJ. and Boeke, JD., 2012, “Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots,” Genome Res. 22(4):693-703. doi: 10.1101/gr.129460.111. Epub 2012 Jan 4, PMCID: PMC3317151Pubmed 

Lessard, JC. and Coulombe, PA., 2012, “Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders,” J Invest Dermatol,132(5):1384-91. PMCID: PMC3326191 Pubmed 

Ewald, AJ., Huebner, RJ., Palsdottir, H., Lee, JK., Perez, MJ., Jorgens, DM., Tauscher, AN., Cheung, KJ., Werb, Z. and Auer, M., 2012, “Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium,” J Cell Sci. 125(Pt 11):2638-54. PMCID: PMC3403234  Pubmed 

Zhong, J., Kim, MS., Chaerkady, R., Wu, X., Huang, TC., Getnet, D., Mitchell, CJ., Palapetta, SM., Sharma, J., O’Meally, RN., Cole, RN., Yoda, A., Moritz, A., Loriaux, MM., Rush, J., Weinstock, DM., Tyner, JW. and Pandey, A., 2012, “TSLP signaling network revealed by SILAC-based phosphoproteomics,” Mol Cell Proteomics. 11(6):M112.017764.PMCID: PMC3433886 Pubmed 

Shirley, MD., Tang, H., Gallione., CJ, Baugher, JD., Frelin, LP., Cohen, B., North, PE., Marchuk, DA., Comi, AM. and Pevsner, J., 2013, “Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ,” N Engl J Med., 368(21):1971-9.  PMCID: PMC3749068 PubMed

West-Foyle, H. and Robinson, DN., 2012, “Cytokinesis mechanics and mechanosensing,” Cytoskeleton, 69(10):700-709. PMCID: PMC3477504 Pubmed 

Herb, BR., Wolschin, F., Hansen, KD., Aryee, MJ., Langmead, B., Irizarry, R., Amdam, GV., and Feinberg, AP., 2012, “Reversible switching between epigenetic states in honeybee behavioral subcastes,” Nat Neurosci. 15(10):1371-3. PMCID: PMC3518384Pubmed 

Hatori, Y., Clasen, S., Hasan, NM., Barry, AN. and Lutsenko, S., 2012, “Functional partnership of the copper export machinery and glutathione balance in human cells,” J Biol Chem. 2287(32):26678-87. PMCID: PMC3411007 Pubmed 

Zhu, H., Cox, E. and Qian, J.,2012, “Functional protein microarray as molecular decathlete: A versatile player in clinical proteomics,” Proteomics Clin Appl. 6(11-12):548-62.  PMCID: PMC3600421 Pubmed

Jilek, BL., Zarr, M., Sampah, ME., Rabi, SA., Bullen, CK., Lai, J., Shen, L. and Siliciano, RF., 2012, “A quantitative basis for antiretroviral therapy for HIV-1 infection,” Nat Med. 18(3):446-51. PMCID: PMC3296892 Pubmed

Carracedo, A., Weiss, D., Leliaert, AK., Bhasin, M., de Boer, VC., Laurent, G., Adams, AC., Sundvall, M., Song, SJ., Ito, K., Finley, LS., Egia, A., Libermann, T., Gerhart-Hines, Z., Puigserver, P., Haigis, MC., Maratos-Flier, E., Richardson, AL., Schafer, ZT. and Pandolfi, PP., 2012, “A metabolic prosurvival role for PML in breast cancer,” J Clin Invest. 122(9):3088-100. PMCID: PMC3433768  Pubmed

Rotty, JD. and Coulombe PA., 2012, “A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair,” J Cell Biol,197(3):381-9. PMCID: PMC3341159  Pubmed

Darby, MM., Serebreni, L., Pan, X., Boeke, JD. and Corden, JL., 2011, “The Saccharomyces cerevisiae Nrd1-Nab3 transcription termination pathway acts in opposition to Ras signaling and mediates response to nutrient depletion,” Mol Cell Biol., 32(10):1762-75. PMCID: PMC3347421Pubmed​ 

Ruch, TR. and Machamer, CE., 2012, “A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein,” PLoS Pathog., 2012;8(5):e1002674. PMCID: PMC3343006  Pubmed 

Stevens, EL., Heckenberg, G., Baugher, JD., Roberson, ED., Downey, TJ. and Pevsner, J., 2012, “Consanguinity in Centre d’Étude du Polymorphisme Humain (CEPH) pedigrees,” Eur J Hum Genet. 20(6):657-67. PMCID: PMC3355261 Pubmed  

Alammar Zaritsky, L., Gama, L. and Clements, JE., 2012, “Canonical type I IFN signaling in simian immunodeficiency virus-infected macrophages is disrupted by astrocyte-secreted CCL2,” J Immunol. 188(8):3876-85. PMCID: PMC3343693 Pubmed 

Shoemaker, CJ. and Green, R., 2012, “Translation drives mRNA quality control,” Nat Struct Mol Biol. 19(6):594-601. PMCID: PMC4299859 Pubmed 

Becker, T., Franckenberg, S., Wickles, S., Shoemaker, CJ.Anger, A.,  Armache, JP., Sieber, H., Ungewickell, C., Berninghausen, O., Dabarkov, I., Karcher, A., Thomm, M., Hopfner, KP., Green, R. and Beckmann, R., 2012, “Structural basis of highly conserved ribosome recycling in eukaryotes  and archaea,” Nature. 482(7386):501-6. PMID: 22358840 Pubmed 

Simon, DN., Domaradzki, T., Hofmann, WA. and Wilson, KL., 2013, “Lamin A tail modification by SUMO1 is disrupted by familial partial lipodystrophy-causing mutations,” Mol Biol Cell., 24(3):342-50. PMCID: PMC3564541  Pubmed 

Huster, D., Kühne, A., Bhattacharjee, A., Raines, L., Jantsch, V., Noe, J., Schirrmeister, W., Sommerer, I., Sabri, O., Berr, F., Mössner, J., Stieger, B., Caca, K. and Lutsenko, S., 2012, “Diverse functional properties of Wilson disease ATP7B variants,” Gastroenterology. 142(4), 947-956. PMCID: PMC3461965 Pubmed 

Currier, DG., Polk, RC. and Reeves, RH., 2012, “A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome,” Prog Brain Res. 197:223-36. PMCID: PMC4405118 Pubmed 

Rodriguez, S. and Wolfgang, MJ., 2012, “Targeted chemical-genetic regulation of protein stability in vivo,” Chem Biol. 19(3):391-8. PMCID: PMC3314227 Pubmed 

DeRose, R., Pohlmeyer, C., Umeda, N., Ueno, T., Nagano, T., Kuo, S. and Inoue, T., 2012, “Spatio-temporal manipulation of small GTPase activity at subcellular level and on timescale of seconds in living cells,” J Vis Exp. (61). pii: 3794. PMCID: PMC3460574 Pubmed 

Dancy, BC., Ming, SA., Papazyan, R., Jelinek, CA., Majumdar, A., Sun, Y., Dancy, BM., Drury, WJ 3rd., Cotter, RJ., Taverna ,SD. and Cole, PA., 2012, “Azalysine analogues as probes for protein lysine deacetylation and demethylation,” J Am Chem Soc. 134(11):5138-48. PMCID: PMC3313494 Pubmed

Miyamoto, T., DeRose, R., Suarez, A., Ueno, T., Chen, M., Sun, TP., Wolfgang, MJ., Mukherjee, C., Meyers, DJ. and Inoue, T., 2012, “Rapid and orthogonal logic gating with a gibberellin-induced dimerization system,” Nat Chem Biol. 8(5):465-70. PMCID: PMC3368803 Pubmed 

Kouser, M., Speed, HE., Dewey, CM., Reimers, JM., Widman, AJ., Gupta, N., Liu, S., Jaramillo, TC., Bangash, M., Xiao, B., Worley, PF. and Powell, CM., 2011, “Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission,” Cell, 145(5):758-72 PMCID: PMC3834052  PubMed

Schaughency, P., Merran, J. and Corden, JL., 2010, “Genome-Wide Mapping of Yeast RNA Polymerase II Termination,” PLoS Genet. 10(10):e1004632.  PMCID: PMC4191890  PubMed

Nguyen-Ngoc, KV., Cheung, KJ., Brenot, A., Shamir, ER., Gray, RS., Hines, WC., Yaswen, P., Werb, Z. and Ewald, AJ., 2012, “ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium,” Proc Natl Acad Sci U S A. 109(39):E2595-604. Epub 2012 Aug 23, PMCID: PMC3465416 PubMed

Wang, JT. and Seydoux, G., 2013, “Germ cell specification,” Adv Exp Med Biol. 757:17-39. Review, PMCID: unknown  Pubmed​

Chan, W., Schaffer, TB. and Pomerantz, JL., 2013, “A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival,” Mol Cell Biol. 33(2):429-43. PMCID: PMC3554118 Pubmed

Shilagardi, K., Li, S., Luo, F., Marikar, F., Duan, R., Jin, P., Kim, JH., Murnen, K. and Chen, EH., 2013, “Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion,” Science. PMCID: PMC3631436 PubMed

Huang, Q., Purzycka, KJ., Lusvarghi, S., Li, D., Legrice, SF. and Boeke, JD., 2013,  “Retrotransposon Ty1 RNA contains a 5′-terminal long-range pseudoknot required for efficient reverse transcription,” RNA. 19(3):320-32. PMCID: PMC3677243 PubMed

Newman, RH., Hu, J., Rho, HS., Xie, Z., Woodard, C., Neiswinger, J., Cooper, C., Shirley, M., Clark, HM., Hu, S., Hwang, W., Jeong, JS., Wu, G., Lin, J., Gao, X., Ni, Q., Goel, R., Xia, S., Ji, H., Dalby, KN., Birnbaum, MJ., Cole, PA., Knapp, S., Ryazanov, AG., Zack, DJ., Blackshaw, S., Pawson, T., Gingras, AC., Desiderio, S., Pandey, A., Turk, BE., Zhang, J., Zhu, H. and Qian, J., 2013, “Construction of human activity-based phosphorylation networks,” Mol Syst Biol. 9:655. PMCID: PMC3658267  PubMed

Stine, RR. and Matunis, EL., 2013,  ‘JAK-STAT signaling in stem cells, ‘ Adv Exp Med Biol. 786:247-67. PMID: 23696361 PubMed

Baile, MG., Whited, K. and Claypool, SM., 2013, “Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling,” Mol Biol Cell. ;24(12):2008-20. PMCID: PMC3681703  PubMed

Zhao, X., Tang, Z., Zhang, H., Atianjoh, FE., Zhao, JY., Liang, L., Wang, W., Guan, X., Kao, SC., Tiwari, V., Gao, YJ., Hoffman, PN., Cui, H., Li, M., Dong, X. and Tao, YX., 2013, “A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons,” Nat Neurosci. 16(8):1024-31 PMCID:  PMC3742386 PubMed

Baugher, JD., Baugher, BD., Shirley, MD and Pevsner, J., 2013, “Sensitive and specific detection of mosaic chromosomal abnormalities using the Parent-of-Origin-based Detection (POD) method,” BMC Genomics. 14:367. PMCID: PMC3680018 PubMed

2000

Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, Vo LT, Zhou Y, North TE, Zon LI, Daley GQ, Schlaeger TM., 2020 Apr 9, “Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System,” Stem Cell Reports pii: S2213-6711(20)30110-7. doi: 10.1016/j.stemcr.2020.03.020. PubMed