OR
Virology and human cancer; antiviral therapy; antitumor therapy; lymphoma pathogenesis and treatment
Building body parts – discovering the mechanisms by which organs achieve their unique architectures and physiological specializations during embryonic development
Structural and molecular mechanisms of nucleic-acid machines and assemblies; control of DNA replication and chromosome superstructure
Role of drug metabolism in non-nucleoside reverse transcriptase inhibitor-mediated toxicity
Fungal pathogenesis: the host-pathogen interaction for the yeast pathogen Candida glabrata
Molecular mechanisms of neuronal death and survival in models of stroke, Parkinson's and Alzheimer’s disease
Molecular and Cellular Studies of Somatosensation, Inflammation, and related diseases
Cellular mechanisms and molecular regulation of epithelial morphogenesis during development and breast cancer
Epigenetics in development and disease
NMR studies of active enzymatic systems: dynamic molecular communication in Nonribosomal Peptide Synthetases
Zinc physiology with a focus on structure, function and regulation of zinc transporters
Molecular mechanisms of programmed cell death and its role in viral pathogenesis
Regulatory pathways that control adaptive metabolic responses in adipose and skeletal muscle tissues
Theoretical modeling, Mechanobiology, Cell Migration, Membrane trafficking, Cell Division
Human copper homeostasis: mechanism of copper transport, regulatory networks, the role in lipid metabolism, disorders of copper misbalance
Molecular Mechanisms of Synapse Formation in Development and Disease
The premature aging disease progeria and lamin A processing; ubiquitin-proteasome mediated protein quality control.
Auditory Perception and Development of Neocortical Circuits
Functional Specificity and Design of Signal Transduction Pathways
Structure, regulation, interfacial enzymology, and functions of lipid metabolizing enzymes involved in signal transduction cascades
Ion transport in health and disease. Emerging roles for Ca2+ signaling and endosomal pH in cancer, autism and neurodegenerative disorders
Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation
Molecular basis of cell-cell interactions in the nervous and immune systems; glycobiology
Molecular Mechanisms and Physiological Roles of Mitochondrial Fusion and Division
Discovery, development and clinical trials of drugs for malaria and sleeping sickness; in vitro pharmacokinetics-pharmacodynamics; long-acting chemoprophylaxis
Neurotransmitters, Second Messengers and Drug Action in the Nervous System
Understanding how biological stress-sensors are assembled, detect danger signals, and initiate stress-response
Cellular and molecular characterizations of rapid changes during synaptic plasticity
Nuclear envelope, lamins and nucleoskeleton; Emery-Dreifuss muscular dystrophy
Structural and molecular mechanisms of ubiquitin signaling and chromatin modification; regulation of transcription
Chromatin remodeling as a fundamental regulator of gene activity
Single-molecule and single-cell studies of cell division, chromosome conformation, transcription and gene regulation
Signal Transduction, protein network, host-pathogen interaction, protein chip approach to study proteomics