My lab’s focus is on the development and application of sequencing technologies to gain a deeper understanding of biology and a more accurate set of clinical tools for human disease. Our research integrates the principles of biophysics, molecular biology, and computational biology to create new tools for exploring the epigenome and genome of various lifeforms, ranging in size from the flu virus to hummingbirds to California redwoods. Based on the knowledge gained from these studies, we apply their toolsets to clinical samples for the diagnosis, surveillance, and treatment of human disease.