
Gregory V. Carr
855 N. Wolfe Street
Rangos 373
Baltimore, MD 21205
Su Y, DePasquale M, Liao G, Buchler I, Zhang G, Byers S, Carr GV, Barrow J, Wei H. Membrane bound catechol-O-methyltransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain. Eur J Pharmacol. 2021: 896: 173909.
Noback M, Zhang G, White N, Barrow JC, Carr GV. Post-weaning social isolation increases ΔFosB/FosB protein experession in sex-specific patterns in the prelimbic/inframlimbic cortex and hippocampus in mice. Neurosci Lett. 2021; 740: 135423.
Byers S, Buchler IP, DePasquale M, Rowley HL, Kulkarni RS, Pinder L, Kolobova A, Li C, Au V, Akuma D, Zhang G, Wei H, Cheetham SC, Barrow JC, Carr GV. Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility. Psychopharmacology. 2020; 237(9): 2695-2707.
Ernst G, Akuma D, Au V, Buchler IP, Byers S, Carr GV, Defays S, de Leon P, Demaude T, DePasquale M, Durieu V, Huang Y, Jigorel E, Kimos M, Kolobova A, Montel F, Moureau F, Poslusney M, Swinnen D, Vandergeten M-C, Van houtvin N, Wei H, White N, Wood M, Barrow JC. Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol-O-Methyltransferase. ACS Med. Chem. Lett. 2019; 10(11): 1573-1578.
Zhang G, Buchler IP, DePasquale M, Wormald M, Liao G, Wei H, Barrow JC, Carr GV. Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors. ACS Chemical Neurosci. 2019; 10(10):4221-4226.