People

Colin Gliech

Colin Gliech

cgliech1@jhmi.edu

Publications

Gliech CR, Holland AJ., 2026, Biological clocks keep a watch on mitosis, Nat Cell Biol., 28(1):13-20. doi: 10.1038/s41556-025-01784-w. PMID: 41495199  PubMed
Hicks CW, Gliech CR, Rahman S, Zhang X, Eneim AS, Vasquez SJ, Holland AJ, Wolberger C., 2025, Haspin kinase binds to a nucleosomal DNA supergroove, Nat Struct Mol Biol., 32(6):1030-1037. doi: 10.1038/s41594-025-01502-y. PMCID: PMC12170164  PubMed
Curinha A, Huang Z, Anglen T, Strong MA, Gliech CR, Jewett CE, Friskes A, Phan TP, Nicholas Z, Holland AJ., 2025, Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome, J Cell Biol., 224(4):e202403022. doi: 10.1083/jcb.202403022. PMCID: PMC11864076  PubMed
Gliech CR, Yeow ZY, Tapias-Gomez D, Yang Y, Huang Z, Tijhuis AE, Spierings DC, Foijer F, Chung G, Tamayo N, Bahrami-Nejad Z, Collins P, Nguyen TT, Plata Stapper A, Hughes PE, Payton M, Holland AJ., 2024, Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition, EMBO J., 43(5):666-694. doi: 10.1038/s44318-024-00031-6. PMCID: PMC10907621  PubMed
Burigotto M, Vigorito V, Gliech C, Mattivi A, Ghetti S, Bisio A, Lolli G, Holland AJ, Fava LL., 2023, PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability, EMBO Rep., 24(12):e57234. doi: 10.15252/embr.202357234. PMCID: PMC10702821  PubMed
Burigotto M, Vigorito V, Gliech C, Mattivi A, Ghetti S, Bisio A, Lolli G, Holland AJ, Fava LL., 2023, PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability, EMBO Rep., e57234. doi: 10.15252/embr.202357234. PMID: 37888778  PubMed
Scott P, Curinha A, Gliech C, Holland AJ., 2023, PLK4 self-phosphorylation drives the selection of a single site for procentriole assembly, J Cell Biol., 222(12):e202301069. doi: 10.1083/jcb.202301069. PMCID: PMC10541313  PubMed
Gliech CR, Holland AJ., 2020, Keeping track of time: The fundamentals of cellular clocks, J Cell Biol., 219(11):e202005136. doi: 10.1083/jcb.202005136. PMCID: PMC7594491  PubMed