People

Shelby Hutcherson

Shelby Hutcherson

Publications

Ghosh A, Jones TA, Mackinnon S, Hutcherson SM, Tritapoe JM, Mongia P, Shah N, Mehlhop EM, Carter NM, Pomerantz JL., 2025, Potentiation of noncanonical NF-κB signaling and marginal zone B cell expansion by CARD11-mediated regulation of p100 processing, Cell Rep., 44(12):116616. doi: 10.1016/j.celrep.2025.116616. PMCID: PMC12818902  PubMed
Carter NM, Hankore WD, Yang YK, Yang C, Hutcherson SM, Fales W, Ghosh A, Mongia P, Mackinnon S, Brennan A, Leone RD, Pomerantz JL., 2025, QRICH1 mediates an intracellular checkpoint for CD8+ T cell activation via the CARD11 signalosome, Sci Immunol., 10(105):eadn8715. doi: 10.1126/sciimmunol.adn8715. PMID: 40085689  PubMed
Bedsaul JR, Shah N, Hutcherson SM, Pomerantz JL., 2022, Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants, iScience, 25(2):103810. doi: 10.1016/j.isci.2022.103810. PMCID: PMC8844825  PubMed
Hutcherson SM, Bedsaul JR, Pomerantz JL., 2021, Pathway-Specific Defects in T, B, and NK Cells and Age-Dependent Development of High IgE in Mice Heterozygous for a CADINS-Associated Dominant NegativeCARD11 Allele, J Immunol., 207(4):1150-1164. doi: 10.4049/jimmunol.2001233, PMCID: PMC8355193. PubMed

Wang Z, Hutcherson SM, Yang C, Jattani RP, Tritapoe JM, Yang YK, Pomerantz JL., 2019, “Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling,” J Biol Chem. 2019 Oct 4;294(40):14648-14660. doi: 10.1074/jbc.RA119.009551. PMCID: PMC6779434 PubMed

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