Recent Publications

2018

Wang, Y., Cho, C., Williams, J., Smallwood, PM., Zhang, C., Junge, HJ. and Nathans, J., 2018, “Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance,” Proc Natl Acad Sci U S A.pii: 201813217.  PMID: 30478038 PubMed
Schaffer, TB., Smith, JE., Cook, EK., Phan, T. and Margolis, SS., 2018, “PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5,” Cell Rep. 25(9):2470-2483.e8. PMID: 30485813. PMCID: PMC6371982 PubMed
Bedsaul, JR., Carter, NM., Deibel, KE., Hutcherson, SM., Jones, TA., Wang, Z., Yang, C., Yang, YK. and Pomerantz, JL., 2018, “Mechanisms of Regulated and Dysregulated CARD11 Signaling in Adaptive Immunity and Disease,” Front Immunol. doi: 10.3389/fimmu.2018.02105. eCollection 2018. Review. PMID: 30283447. PMCID: PMC6156143 PubMed
Zhu, L., Kandasamy, SK., Liao, SE. and Fukunaga, R., 2018, “LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes,” Nat Commun. 9(1):4031. PMCID: PMC6168497 PubMed   
Schmidt, K., Ralle, M., Schaffer, T., Jayakanthan, S., Bari, B., Muchenditsi, A. and Lutsenko, S., 2018, “ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal DOPAMINE-β-HYDROXYLASE,” J Biol Chem. pii: jbc.RA118.004889. PMID: 30341172 PubMed
Prasad, S., Huang, J., Zeng, Q., Brooks, BR., 2018, An explicit-solvent hybrid QM and MM approach for predicting pKa of smallmolecules in SAMPL6 challenge, J Comput Aided Mol Des. 32(10):1191-1201, PMID: 30276503. PubMed  
Braun, E., Gilmer, J., Mayes, H., Mobley, D., Monroe, J., Samarjeet, S.P., Zuckerman, D., 2018, Best Practices for Foundations in Molecular Simulations 
Salvatierra J, Diaz-Bustamante M, Meixiong J, Tierney E, Dong X, Bosmans F. 2018 Dec 3. “A disease mutation reveals a role for NaV1.9 in acute itch.” J Clin Invest. 128(12):5434-5447. doi: 10.1172/JCI122481. Epub 2018 Nov 5. PMID: 30395542. PMCID: PMC6264633. PubMed  
Chevée M, Brown SP. 2018 Dec. "The development of local circuits in the neocortex: recent lessons from the mouse visual cortex." Curr Opin Neurobiol. 53:103-109. PMID: 30053693. PMCID: PMC6427921. PubMed
Tammia M, Mi R, Sluch VM, Zhu A, Chung T, Shinn D, Zack DJ, Höke A, Mao HQ. 2018 "Egr2 overexpression in Schwann cells increases myelination frequency in vitro," Heliyon. 4(11):e00982 PubMed
Ryals M, Morell RJ, Martin D, Boger ET, Wu P, Raible DW, Cunningham LL., 2018, "The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity." Front Cell Neurosci. 12:445. PubMed  
Prasad S, Huang J, Zeng Q, Brooks BR. 2018 Oct 1. “An explicit-solvent hybrid QM and MM approach for predicting pKa of small molecules in SAMPL6 challenge.” J Comput Aided Mol Des.;32(10):1191-1201. doi: 10.1007/s10822-018-0167-1.PMID: 30276503. PMCID: PMC6342563. PubMed.  
Chen S, Luperchio TR, Wong X, Doan EB, Byrd AT, Roy Choudhury K, Reddy KL, Krangel MS. (2018) "A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus," Cell Rep. 25(7):1729-1740.e6. PMID: 30428344. PMCID: PMC6287930. PubMed
Metz KA, Teng X, Coppens I, Lamb HM, Wagner BE, Rosenfeld JA, Chen X, Zhang Y, Kim HJ, Meadow ME, Wang TS, Haberlandt ED, Anderson GW, Leshinsky-Silver E, Bi W, Markello TC, Pratt M, Makhseed N, Garnica A, Danylchuk NR, Burrow TA, Jayakar P, McKnight D, Agadi S, Gbedawo H, Stanley C, Alber M, Prehl I, Peariso K, Ong MT, Mordekar SR, Parker MJ, Crooks D, Agrawal PB, Berry GT, Loddenkemper T, Yang Y, Maegawa GHB, Aouacheria A, Markle JG, Wohlschlegel JA, Hartman AL, Hardwick JM. 2018 Nov. “KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect.” Ann Neurol.;84(5):766-780. doi: 10.1002/ana.25351. Epub 2018 Nov 8. PMID: 30295347. PubMed  
Phua, SC., Nihongaki, Y. and Inoue, T., 2018, “Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides,” Curr Opin Cell Biol.; 50:72-78. PMCID: PMC5911401 PubMed
Tung B, Ma D, Wang S, Oyinlade O, Laterra J, Ying M, Lv SQ, Wei S, Xia S., 2018, "Krüppel-like factor 9 and histone deacetylase inhibitors synergistically induce cell death in glioblastoma stem-like cells." BMC Cancer. 18(1):1025. PubMed
Zhu, J., Tsai, HJ., Gordon, MR., Li, R., 2018, “Cellular Stress Associated with Aneuploidy,” Dev Cell. 44(4):420-431. PMID: 29486194 PubMed  
Wu, M., Hayward, D., Kalin, JH., Song, Y., Schwabe, JW., Cole, PA., 2018, “Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex,” Elife. 7. pii: e37231. PMCID: PMC6019071 PubMed
Salvatierra, J., Castro, J., Erickson, A., Li, Q., Braz, J., Gilchrist, J., Grundy, L., Rychkov, GY., Deiteren, A., Rais, R., King, GF., Slusher, BS., Basbaum, A., Pasricha, PJ., Brierley, SM. and Bosmans, F., 2018, “NaV1.1 inhibition can reduce visceral hypersensitivity,” JCI Insight. 3(11). pii: 121000. PMCID: PMC6124407 PubMed
 Liao, SE. and Fukunaga, R., 2018, “Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro,” Methods Mol Biol. 1680:101-121. PMID: 29030844 PubMed
Levine, MS. and Holland, AJ., 2018, “The impact of mitotic errors on cell proliferation and tumorigenesis,” Genes Dev.;32(9-10):620-638. PMCID: PMC6004076 [Available on 2018-11-01] PubMed
Duan, R., Kim, JH., Shilagardi, K., Schiffhauer, ES., Lee, DM., Son, S., Li, S., Thomas, C., Luo, T., Fletcher, DA., Robinson, DN. and Chen, EH., 2018, “Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion,” Nat Cell Biol. 20(6):688-698. PMID: 29802406 PubMed
Lambrus, BG., Moyer, TC. and Holland, AJ., 2018, “Applying the auxin-inducible degradation system for rapid protein depletion in mammalian cells,” Methods Cell Biol. 144:107-135. 5. PMID: 29804665 PubMed
Sanders, S., Bartee, D., Harrison, MJ., Phillips, PD., Koppisch, AT. and Freel Meyers, CL., 2018, “Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors,” PLoS One. 13(5):e0197638. PMCID: PMC5957436 PubMed
Schuller, AP. and Green, R., 2018, “Roadblocks and resolutions in eukaryotic translation,” Nat Rev Mol Cell Biol. PMCID: PMC6054806 [Available on 2019-02-01] PubMed
Neumann, NM., Perrone, MC., Veldhuis, JH., Huebner, RJ., Zhan, H., Devreotes, PN., Brodland, GW., and Ewald, AJ., 2018, “Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation,” Dev Cell. 45(1):67-82.e6. PMCID: PMC5983037 [Available on 2019-04-09] PubMed
Little HC, Tan SY, Cali FM, Rodriguez S, Lei X, Wolfe A, Hug C, Wong GW., 2018, “Multiplex Quantification Identifies Novel Exercise-regulated Myokines/Cytokines in Plasma and in Glycolytic and Oxidative Skeletal Muscle”, Mol Cell Proteomics. 17(8):1546-1563. PMCID: PMC6072542. PubMed                      
Liao, SE., Ai, Y. and Fukunaga, R., 2018, “An RNA-binding protein Blanks plays important roles in defining small RNA and mRNA profiles in <i>Drosophila</i> testes,” Heliyon. 2018 Jul 25;4(7):e00706. eCollection. PMCID: PMC6074722 PubMed
Ramachandran, KV., Fu, JM., Schaffer, TB., Na, CH., Delannoy, M. and Margolis, SS., 2018, “Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome,” Mol Cell. 71(1):169-177.e6. PMCID: PMC6070390 [Available on 2019-07-05] PubMed
Sundararajan, K., Vecchiarelli, A., Mizuuchi, K. and Goley, ED., 2018, “Species- and C-terminal linker-dependent variations in the dynamic behavior of FtsZ on membranes in vitro,” Mol Microbiol. PMID: 30010220. PMCID: PMC6195856. PubMed
Divakaruni, AS., Hsieh, WY., Minarrieta, L., Duong, TN., Kim, KKO., Desousa, BR., Andreyev, AY., Bowman, CE., Caradonna, K., Dranka, BP., Ferrick, DA., Liesa, M., Stiles, L., Rogers, GW., Braas, D., Ciaraldi, TP., Wolfgang, MJ., Sparwasser, T., Berod, L., Bensinger, SJ. and Murphy, AN., 2018, “Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis,” Cell Metab. 2018 Jun 16. pii: S1550-4131(18)30383-8.  PMCID: PMC6125190 [Available on 2019-09-04] PubMed
Sirka OK, Shamir ER, Ewald AJ. 2018 Oct 1. “Myoepithelial cells are a dynamic barrier to epithelial dissemination.” J Cell Biol. 217(10):3368-3381. doi: 10.1083/jcb.201802144. Epub 2018 Jul 30. PMID: 30061105. PMCID: PMC6168248. PubMed.  
Eldred KC, Hadyniak SE, Hussey KA, Brenerman B, Zhang PW, Chamling X, Sluch VM, Welsbie DS, Hattar S, Taylor J, Wahlin K, Zack DJ, Johnston RJ Jr. 2018 "Thyroid hormone signaling specifies cone subtypes in human retinal organoids," Science. 362(6411). PubMed
Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. 2018 Sep 4. “Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis.”Cell Metab.;28(3):490-503.e7. doi: 10.1016/j.cmet.2018.06.001. Epub 2018 Jun 28. PMID: 30043752. PMCID: PMC6125190. PubMed.  
Fligor CM, Langer KB, Sridhar A, Ren Y, Shields PK, Edler MC, Ohlemacher SK, Sluch VM, Zack DJ, Zhang C, Suter DM, Meyer JS., 2018, "Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells." Sci Rep. 8(1):14520. PubMed
Veenhuis RT, Kwaa AK, Garliss CC, Latanich R, Salgado M, Pohlmeyer CW, Nobles CL, Gregg J, Scully EP, Bailey JR, Bushman FD, Blankson JN. 2018 Sep 20. “Long-term remission despite clonal expansion of replication-competent HIV-1 isolates.” JCI Insight.;3(18). pii: 122795. doi: 10.1172/jci.insight.122795. eCollection 2018 Sep 20. PMID: 30232278. PMCID: PMC6237238. PubMed.  
Zhou Y, Bond AM, Shade JE, Zhu Y, Davis CO, Wang X, Su Y, Yoon KJ, Phan AT, Chen WJ, Oh JH, Marsh-Armstrong N, Atabai K, Ming GL, Song H. 2018 Sep 6. “Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool.” Cell Stem Cell. 23(3):444-452.e4. doi: 10.1016/j.stem.2018.08.005. Epub 2018 Aug 30. PMID: 30174295. PMCID: PMC6128767. PubMed.  
Greenspan LJ, Matunis EL., 2018, "Retinoblastoma Intrinsically Regulates Niche Cell Quiescence, Identity, and Niche Number in the Adult Drosophila Testis." Cell Rep. 24(13):3466-3476.e8. PubMed
Wei S, Wang J, Oyinlade O, Ma D, Wang S, Kratz L, Lal B, Xu Q, Liu S, Shah SR, Zhang H, Li Y, Quiñones-Hinojosa A, Zhu H, Huang ZY, Cheng L, Qian J, Xia S., 2018, "Heterozygous IDH1R132H/WT created by "single base editing" inhibits human astroglial cell growth by downregulating YAP." Oncogene. 37(38):5160-5174. PubMed
Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, Bosmans F. 2018 Jun 7. “NaV1.1 inhibition can reduce visceral hypersensitivity” JCI Insight 3(11). pii: 121000. doi: 10.1172/jci.insight.121000. eCollection 2018 Jun 7. PMID: 29875317. PMCID: PMC6124407. PubMed.
Dadi H, Jones TA, Merico D, Sharfe N, Ovadia A, Schejter Y, Reid B, Sun M, Vong L, Atkinson A, Lavi S, Pomerantz JL, Roifman CM. 2018 May. “Combined immunodeficiency and atopy caused by a dominant negative mutation in caspase activation and recruitment domain family member 11 (CARD11).” J Allergy Clin Immunol.;141(5):1818-1830.e2. doi: 10.1016/j.jaci.2017.06.047. Epub 2017 Aug 19. PMID: 28826773. PubMed.  
Goodwin CR, Rath P, Oyinlade O, Lopez H, Mughal S, Xia S, Li Y, Kaur H, Zhou X, Ahmed AK, Ho S, Olivi A, Lal B., 2018, "Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts." Clin Neurol Neurosurg. 171:26-33. PubMed  
El-Diwany R, Soliman M, Sugawara S, Breitwieser F, Skaist A, Coggiano C, Sangal N, Chattergoon M, Bailey JR, Siliciano RF, Blankson JN, Ray SC, Wheelan SJ, Thomas DL, Balagopal A. 2018 Aug 1. “CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans.” Sci Adv. 4(8):eaat0843. doi: 10.1126/sciadv.aat0843. eCollection 2018 Aug. PMID: 30083606. PMCID: PMC6070316. PubMed.  
Han L, Limjunyawong N, Ru F, Li Z, Hall OJ, Steele H, Zhu Y, Wilson J, Mitzner W, Kollarik M, Undem BJ, Canning BJ, Dong X., 2018 Mar. "Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyper-responsiveness." Nat Neurosci, 21(3):324-328. doi: 10.1038/s41593-018-0074-8. PMCID: PMC5857222. PubMed.
Gonzalez-Hurtado E, Lee J, Choi J, Wolfgang MJ., 2018 Jan, "Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing." Mol Metab, doi: 10.1016/j.molmet.2017.11.004. PMCID: PMC5784326. PubMed.
Cairns, L., Tran, T., Fowl, BH., Patterson, A., Kim, YJ., Bothner, B. and Kavran, JM., 2018, “Salvador has an extended SARAH domain that mediates binding to Hippo kinase,” J Biol Chem. pii: jbc.RA117.000923. PMCID: PMC5900767 PubMed
Oldach, LM., Gorshkov, K., Mills, WT. 4th,  Zhang, J. and Meffert, MK., 2018, “A Biosensor for MAPK-Dependent Lin28 Signaling,” Mol Biol Cell. pii: mbc.E17-08-0500. PMCID: PMC5935066 PubMed
Yoon, KJ., Vissers, C., Ming, GL. and Song, H., 2018, “Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence,” J Cell Biol. pii: jcb.201802117. Review. PMCID: PMC5987727 PubMed
Kalin, JH., Wu, M., Gomez, AV., Song, Y., Das, J., Hayward, D., Adejola, N., Wu, M., Panova, I., Chung, HJ., Kim, E., Roberts, HJ., Roberts, JM., Prusevich, P., Jeliazkov, JR., Roy Burman, SS., Fairall, L., Milano, C., Eroglu, A., Proby, CM., Dinkova-Kostova, AT., Hancock, WW., Gray, JJ., Bradner, JE., Valente, S., Mai, A., Anders, NM., Rudek, MA., Hu, Y., Ryu, B., Schwabe, JWR., Mattevi, A., Alani, RM. and Cole, PA., 2018, “Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors,” Nat Commun. 9(1):53. PMCID: PMC5754352 PubMed
Wang, S., Shi, X., Wei, S., Ma, D., Ajala, O., Lv, SQ., Ying, M., Zhang, YA., Claypool, SM., Watkins, P. and Xia, S., 2018, “Krüppel-like factor 4 (KLF4) induces mitochondrial fusion and increases spare respiratory capacity of human glioblastoma cells,” J Biol Chem. pii: jbc.RA117.001323. PMCID: PMC5925822 PubMed

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