Erin Goley

The growing crisis in antibiotic resistance necessitates a complete molecular understanding of the mechanisms and regulation of bacterial growth and replication to inform development of new drugs. Our laboratory aims to elucidate the mechanisms bacteria use to grow and...

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Jie Xiao

My laboratory focuses on developing novel single-molecule imaging tools in live cells to probe various dynamic aspects of cellular processes. We develop single-molecule gene expression reporting systems and chromosomal DNA conformation markers to probe the dynamics of gene regulation...

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Tamara O'Connor

The outcome of most parasitic relationships is decided by an elaborate series of events involving hundreds of proteins. Understanding this interaction requires the analysis of the molecular mechanisms operating in both organisms and the causal relationships acting at the...

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Joshua Modell

CRISPR-Cas loci serve as acquired immune systems which protect their bacterial and archaeal hosts from viruses and plasmids. CRISPR immunity occurs in two phases: First, short DNA segments from foreign invaders are captured and inserted into the CRISPR locus...

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