Xinzhong Dong

My laboratory has taken a multidisciplinary approach to understand the cellular and molecular mechanisms of different types of somatosensations including pain and itch, which are initiated and mediated by primary sensory neurons in dorsal root ganglia (DRG). We identified...

Read More

Loyal Goff

The goal of my research program is to answer a fundamental biological question: how is the genome properly interpreted to coordinate the diversity of cell types observed during neuronal development? We are focused on the acquisition of specific cellular...

Read More

Richard Huganir

Neurotransmitter receptors mediate signal transduction at the postsynaptic membrane of synaptic connections between neurons in the nervous system. We have been studying the molecular mechanisms in the regulation of neurotransmitter receptor function. Recently we have focused on glutamate receptors,...

Read More

Alex Kolodkin

Research in my laboratory is focused on understanding how neuronal connectivity is established during development. Our work investigates the function of extrinsic guidance cues and their receptors on axonal guidance, dendritic morphology, and synapse formation and function. For several...

Read More

Solange Brown

Our research takes a bottom-up approach to understanding how the neural circuits of this massively interconnected network of neurons are functionally organized and how dysfunction in these circuits contributes to neurodegenerative diseases like amyotrophic lateral sclerosis and neuropsychiatric disorders...

Read More

Angelika Doetzlhofer

Auditory hair cells, located in the inner ear cochlea are critical for our ability to detect sound. In mammals, neural innervated hair cells come in two flavors: inner hair cells, which are our primary mechanoreceptor and relay sound information...

Read More

Paul Worley

The focus of our research is to identify mechanisms of protein synthesis-dependent neuronal plasticity. The approach uses differential cloning techniques to identify mRNAs that are rapidly induced in neurons by synaptic activity. Classical studies established that rapid, de novo...

Read More

King-Wai Yau

Our laboratory is interested in the area of sensory transduction: specifically visual and olfactory transductions, which are the processes by which the senses of vision and olfaction are initiated. These two processes have interesting similarities and differences. Vision can...

Read More

Seth Blackshaw

The vertebrate central nervous system (CNS) is an amazingly complex structure composed of distinct subtypes of neurons and glia. Our lab aims to identify the molecular mechanisms that control the generation of the major cell types of the vertebrate...

Read More

Solomon H. Snyder

Neurotransmitters, Second Messengers and Drug Action in the Nervous System Our lab studies diverse signaling systems including those of neurotransmitters and second messengers as well as the actions of drugs upon these processes. We have been interested in...

Read More