Thomas Schaffer


Columbia Biosciences Corporation

BS, The Pennsylvania State University

2018

Alumni

Name Graduation Year
Thomas Schaffer 2018

Publications

  • Sell GL, Xin W, Cook EK, Zbinden MA, Schaffer TB, O'Meally RN, Cole RN, Margolis SS., 2021, Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice, Sci Rep., 11(1):19414. doi: 10.1038/s41598-021-97898-w. PMCID: PMC8484563.  PubMed

  • Schmidt, K., Ralle, M., Schaffer, T., Jayakanthan, S., Bari, B., Muchenditsi, A. and Lutsenko, S., 2018, “ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal DOPAMINE-β-HYDROXYLASE,” J Biol Chem. pii: jbc.RA118.004889. PMID: 30341172 PubMed

  • Schaffer, TB., Smith, JE., Cook, EK., Phan, T. and Margolis, SS., 2018, “PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5,” Cell Rep. 25(9):2470-2483.e8. PMID: 30485813. PMCID: PMC6371982 PubMed

  • Sell, GL., Schaffer, TB., and Margolis, SS., 2017 “Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice,” J Clin Invest. pii: 85504. PMCID: PMC5409082 PubMed

  • Chan, W., Schaffer, TB. and Pomerantz, JL., 2013, "A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival," Mol Cell Biol. 33(2):429-43. PMCID: PMC3554118 Pubmed