Photo of Taeyoung Hwang

Taeyoung Hwang

RNA is typically understood as an intermediary molecule between DNA and protein. But, many noncoding RNAs, as well as the noncoding regions of messenger RNA, are increasingly appreciated as important regulators of gene expression and cellular functions. The forefront...

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Image of Michael Piacentino

Piacentino, Michael

Epithelial-to-mesenchymal transition (EMT) is a cellular lifestyle change that produces highly invasive cells that can migrate long distances in the body. These processes are critical for normal embryonic development but are often reactivated in disease states such as cancer...

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Photo of Justus Kebschull

Kebschull, Justus

Understanding the brain using evolution, viruses, and barcode sequencing. Our research aims to understand the structure and function of the brain. To do so, we take a comparative approach and develop molecular, viral, and sequencing technologies to measure neuronal...

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Photo of Bindu Paul

Bindu Paul

Redox regulation plays a central role in signal transduction processes operating in the brain. Aberrant redox signaling is a hallmark of several neurodegenerative diseases such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis and various Ataxias. It...

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Peter Espenshade

Our laboratory’s research focuses on understanding (1) how cells measure levels of available nutrients and (2) how cells adapt to changes in nutrient supply to control metabolic homeostasis. Our studies have primarily centered on changes in cholesterol and oxygen...

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Andrew Feinberg

Understanding how the information in the genome is utilized is one of the central questions in modern biology. It has become clear that a critical level of gene regulation occurs through the chemical modification of both the DNA itself...

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Loyal Goff

The goal of my research program is to answer a fundamental biological question: how is the genome properly interpreted to coordinate the diversity of cell types observed during neuronal development? We are focused on the acquisition of specific cellular...

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Seth Blackshaw

The vertebrate central nervous system (CNS) is an amazingly complex structure composed of distinct subtypes of neurons and glia.  Our lab aims to identify the molecular mechanisms that control the generation of the major cell types of the vertebrate...

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Solange Brown

Our research takes a bottom-up approach to understanding how the neural circuits of this massively interconnected network of neurons are functionally organized and how dysfunction in these circuits contributes to neurodegenerative diseases like amyotrophic lateral sclerosis and neuropsychiatric disorders...

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