Photo of Taeyoung Hwang

Taeyoung Hwang

RNA is typically understood as an intermediary molecule between DNA and protein. But, many noncoding RNAs, as well as the noncoding regions of messenger RNA, are increasingly appreciated as important regulators of gene expression and cellular functions. The forefront...

Read More
Image of Michael Piacentino

Piacentino, Michael

Epithelial-to-mesenchymal transition (EMT) is a cellular lifestyle change that produces highly invasive cells that can migrate long distances in the body. These processes are critical for normal embryonic development but are often reactivated in disease states such as cancer...

Read More
Image of Genevieve Stein-O'Brien

Genevieve Stein-O’Brien

Single cell gene molecular profiling has demonstrated that cell classification requires more than a simple collection of markers. Current approaches do not account for the dynamic nature of cell states and inherent variation in cell types. This is especially...

Read More

Andrew Feinberg

Understanding how the information in the genome is utilized is one of the central questions in modern biology. It has become clear that a critical level of gene regulation occurs through the chemical modification of both the DNA itself...

Read More

Patrick Cahan

My lab is an interdisciplinary group that devises and experimentally tests computational tools to explore cell type identity and its molecular underpinnings. A unifying component of our research is the gene regulatory network (GRN). GRNs are programs encoded in...

Read More

Erika Matunis

What are cellular and molecular mechanisms that control tissue regeneration in vivo?  Stem cells ensure tissue renewal in most adult tissues, and their activities are under the precise control of signals from specific local microenvironments, or niches. The ability...

Read More

Reza Kalhor

Our research seeks to map and engineer cell fate using synthetic biology and genomics approaches. To accomplish this objective, we develop: (A) molecular technologies that write cellular histories into their genomes, (B) sequencing strategies that read out written information...

Read More
Image of Brady Maher

Brady J. Maher

My lab is focused on understanding fundamental mechanisms involved in brain development and brain function with an emphasis on how dysfunction in these mechanisms can result in neurodevelopmental and psychiatric disorders. By focusing on key developmental genes that are...

Read More

Luis Garza

What if you could grow a new heart or liver if your first one failed? Our lab is interested if organogenesis can happen again in adults. We use skin as our model system and try to ask basic questions...

Read More

Ulrich Mueller

MECHANOTRANSDUCTION AND AUDITORY PERCEPTION Hair cells in the inner ear are mechanosensors for the perception of sound and head movements. Sound signals directly activate mechanically gated ion channels in hair cells, leading to hair cell depolarization and the release...

Read More