Photo of Justus Kebschull

Kebschull, Justus

In the Kebschull Lab, we ask how brain areas, circuits, and cell types change across evolution to produce the complex network architecture of extant vertebrate brains. Answering these questions will not only teach us about evolution but reveal general...

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Williams, Dionna

The Williams Lab seeks to identify the fundamental mechanisms by which HIV, drugs of abuse, and the antiretroviral therapies used to treat the virus synergize to promote damage to the body. One of the major challenges in HIV eradication...

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Bindu Paul

Redox regulation plays a central role in signal transduction processes operating in the brain. Aberrant redox signaling is a hallmark of several neurodegenerative diseases such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis and various Ataxias. It...

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Carolyn Machamer

We are interested in the structure and function of the Golgi complex, a ubiquitous eukaryotic organelle that plays a central role in post-translational processing and sorting of newly synthesized proteins and lipids in the secretory pathway. The Golgi complex...

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Stephen Gould

Animal cells secrete small vesicles (~50-250 nm diameter) that have the same topology as the cell. These vesicles, known as exosomes and microvesicles (EMVs), can be taken up by neighboring cells, completing a pathway of intercellular vesicle traffic. Our...

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J. Marie Hardwick

Our laboratory studies the basic molecular mechanisms of programmed cell death, an evolutionarily conserved process to eliminate cells. Because these pathways normally contribute to the millions of cell deaths that occur per day per individual, defects in cell death...

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Janice Clements

Research in the Retrovirus Laboratory focuses on the molecular virology and pathogenesis of lentivirus infections. In particular, the simian immunodeficiency virus (SIV) is used to examine the molecular basis for the pathogenesis of HIV CNS disease. Research projects include...

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Robert Siliciano

For the 34 million people infected with HIV-1, the best current hope for avoiding the fatal consequences of the infection lies in treatment with antiretroviral therapy (ART), which consists of combinations of three drugs that inhibit specific steps in...

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Richard Ambinder

Epstein-Barr virus and Kaposi’s sarcoma herpesvirus are found in association with a variety of cancers. Our laboratory studies are aimed at better defining the role(s) of the virus in the pathogenesis of these diseases and the development of strategies...

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Joel L. Pomerantz

My laboratory is interested in the molecular mechanisms by which cells interpret signals from their environment that instruct them to proliferate, differentiate, or die by apoptosis. This process is of fundamental importance in the development and function of the...

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