Joshua Modell

CRISPR-Cas loci serve as acquired immune systems which protect their bacterial and archaeal hosts from viruses and plasmids. CRISPR immunity occurs in two phases: First, short DNA segments from foreign invaders are captured and inserted into the CRISPR locus...

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Winston Timp

My lab’s focus is on the development and application of sequencing technologies to gain a deeper understanding of biology and a more accurate set of clinical tools for human disease. Our research integrates the principles of biophysics, molecular biology,...

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Mark Wu

Each day, animals engage in goal-directed behaviors to satisfy innate drives, such as the need for sleep, food, and water. Despite the essential nature of these behaviors, many of the molecular and neural circuit mechanisms underlying these behaviors remain...

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Ulrich Mueller

MECHANOTRANSDUCTION AND AUDITORY PERCEPTION Hair cells in the inner ear are mechanosensors for the perception of sound and head movements. Sound signals directly activate mechanically gated ion channels in hair cells, leading to hair cell depolarization and the release...

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