Loyal Goff

The goal of my research program is to answer a fundamental biological question: how is the genome properly interpreted to coordinate the diversity of cell types observed during neuronal development? We are focused on the acquisition of specific cellular...

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Rachel Green

The ribosome is the macromolecular complex that translates the genetic code into functional polypeptides. We are interested in how this ribonucleoprotein (RNA + protein) machine catalyzes and coordinates the complex molecular events of translation. Current work in the Green...

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Taekjip Ha

My research is focused on pushing the limits of single-molecule detection methods to study complex biological systems. His group develops state-of-the-art biophysical techniques (e.g., multicolor fluorescence, super-resolution imaging, combined force and fluorescence spectroscopy, vesicular encapsulation, single-molecule pull-down) and applies...

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Andrew Feinberg

Understanding how the information in the genome is utilized is one of the central questions in modern biology. It has become clear that a critical level of gene regulation occurs through the chemical modification of both the DNA itself...

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Ryuya Fukunaga

The Fukunaga lab is broadly interested in RNA biology. More specifically, the Fukunaga lab investigates the mechanism and biology of post-transcriptional gene regulation controlled by small silencing RNAs and RNA-binding proteins. Our research projects will answer fundamental biological questions...

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Seth Blackshaw

The vertebrate central nervous system (CNS) is an amazingly complex structure composed of distinct subtypes of neurons and glia. Our lab aims to identify the molecular mechanisms that control the generation of the major cell types of the vertebrate...

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Michael Caterina

My lab studies mechanisms underlying pain sensation, using a combination of mouse genetics and a range of in vitro and in vivo assays that include behavior, electrophysiology, imaging, neuroanatomy, and biochemistry. Among the areas of focus in the lab...

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Angelika Doetzlhofer

Auditory hair cells, located in the inner ear cochlea are critical for our ability to detect sound. In mammals, neural innervated hair cells come in two flavors: inner hair cells, which are our primary mechanoreceptor and relay sound information...

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Sean Taverna

Eukaryotic cells package their genomes in the form of chromatin, which is comprised of histone proteins and DNA. Modification of chromatin by chemical marks such as methylation and acetylation affects how cellular machineries interpret the genome. The Taverna laboratory...

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Mollie K. Meffert

How are gene programs regulated to modify the brain during experience and disease? The Meffert lab studies molecular mechanisms underlying enduring changes in brain function. We are interested in understanding how programs of gene expression are coordinated and maintained...

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