Xinzhong Dong

My laboratory has taken a multidisciplinary approach to understand the cellular and molecular mechanisms of different types of somatosensations including pain and itch, which are initiated and mediated by primary sensory neurons in dorsal root ganglia (DRG). We identified...

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Richard Huganir

Neurotransmitter receptors mediate signal transduction at the postsynaptic membrane of synaptic connections between neurons in the nervous system. We have been studying the molecular mechanisms in the regulation of neurotransmitter receptor function. Recently we have focused on glutamate receptors,...

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Michael Caterina

Our laboratory studies the molecular and cellular mechanisms underlying the perception of pain under healthy conditions and in the setting of pathology.  Towards this goal, we utilize a wide spectrum of approaches including behavioral analysis, in vivo and in...

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Angelika Doetzlhofer

Auditory hair cells, located in the inner ear cochlea are critical for our ability to detect sound. In mammals, neural innervated hair cells come in two flavors: inner hair cells, which are our primary mechanoreceptor and relay sound information...

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King-Wai Yau

Our laboratory is interested in the area of sensory transduction: specifically visual and olfactory transductions, which are the processes by which the senses of vision and olfaction are initiated. These two processes have interesting similarities and differences. Vision can...

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Solange Brown

Our research takes a bottom-up approach to understanding how the neural circuits of this massively interconnected network of neurons are functionally organized and how dysfunction in these circuits contributes to neurodegenerative diseases like amyotrophic lateral sclerosis and neuropsychiatric disorders...

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Shigeki Watanabe

My lab studies the cellular and molecular basis of synaptic transmission and plasticity. Neuronal signaling events at synapses determine circuit responses and result in specific behavioral outputs. This signaling is dynamic – modulated by synapse activity history and perceived...

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Jeremy Nathans

Biology: Frizzled receptors in development and disease   Our laboratory has focused for the past two decades on a large family of cell-surface receptors called Frizzled. This name refers to the appearance of fruit flies in which the receptor...

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Jennifer Pluznick

Our lab is interested in the role that chemosensation plays in regulating physiological processes, particularly in the kidney and the cardiovascular system. We have found that sensory receptors (olfactory receptors, taste receptors, and other G-protein coupled receptors) are expressed...

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Christopher J. Potter

The current research focus of my laboratory is investigating the olfactory system of Anopheles mosquitoes. We have developed new strains of Anopheles mosquitoes, utilizing the Q-system we originally developed for use in Drosophila, to explore how living Anopheles mosquitoes...

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