Photo of Diane Peters

Diane Peters

The Peters lab applies a translational medicine approach to study the pathobiology of inflammatory bowel disease (IBD), with the ultimate goal of developing mechanistically novel IBD therapeutics. Our laboratory uses preclinical rodent colitis models and genetically modified mice to...

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Image of Bethany Powell Gray

Bethany Powell Gray

Using nucleic acid chemistry and biology to create safer cancer drugs and tunable imaging agents for cancer detection. Traditionally antibodies have been considered the gold standard of targeting ligands, able to specifically target desired cellular targets with high affinity....

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Photo of Luisa Cochella

Luisa Cochella

The evolution of multicellularity occurred hand in hand with the diversification of cell types with disparate morphologies and functions. This segregation of function across different cell types enabled astounding animal complexity; but at the same time, extreme specializations of...

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Photo of Justus Kebschull

Kebschull, Justus

Understanding the brain using evolution, viruses, and barcode sequencing. Our research aims to understand the structure and function of the brain. To do so, we take a comparative approach and develop molecular, viral, and sequencing technologies to measure neuronal...

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Bindu Paul

Redox regulation plays a central role in signal transduction processes operating in the brain. Aberrant redox signaling is a hallmark of several neurodegenerative diseases such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis and various Ataxias. It...

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Albert Lau

Research in my laboratory is focused on understanding the molecular mechanisms of multi-subunit assemblies involved in synaptic communication. We are particularly interested in elucidating the structural thermodynamics that govern subunit assembly, ligand binding, and allosteric control of neurotransmitter receptors....

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Jun Liu

Our primary research interest lies at the interface between chemistry, biology and medicine. We seek to discover new chemical ligands to modulate signaling pathways and cellular processes of interest by conducting high-throughput screening of chemical libraries we generate or...

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Svetlana Lutsenko

Copper plays an essential role in human physiology. It serves as a cofactor to key metabolic enzymes that are required for respiration, neurotransmitter biosynthesis, detoxification of radicals, blood clotting, connective tissue formation, and many others processes. Through currently unknown...

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Andrew Ewald

Background and Summary: Epithelial cells in a tissue live a crowded life connected to, and interacting with, other cell types, the extracellular matrix, and diverse signaling molecules. A fundamental question in biology is: how do the constituent cells of an...

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Andrew Feinberg

Understanding how the information in the genome is utilized is one of the central questions in modern biology. It has become clear that a critical level of gene regulation occurs through the chemical modification of both the DNA itself...

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