Ryuya Fukunaga

The Fukunaga lab is broadly interested in RNA biology. More specifically, the Fukunaga lab investigates the mechanism and biology of post-transcriptional gene regulation controlled by small silencing RNAs and RNA-binding proteins. Our research projects will answer fundamental biological questions...

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Loyal Goff

The goal of my research program is to answer a fundamental biological question: how is the genome properly interpreted to coordinate the diversity of cell types observed during neuronal development? We are focused on the acquisition of specific cellular...

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Erin Goley

The growing crisis in antibiotic resistance necessitates a complete molecular understanding of the mechanisms and regulation of bacterial growth and replication to inform development of new drugs. Our laboratory aims to elucidate the mechanisms bacteria use to grow and...

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Stephen Gould

Animal cells secrete small vesicles (~50-250 nm diameter) that have the same topology as the cell. These vesicles, known as exosomes and microvesicles (EMVs), can be taken up by neighboring cells, completing a pathway of intercellular vesicle traffic. Our...

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Rachel Green

The ribosome is a complex molecular machine that translates the genetic code into functional polypeptides. Our work focuses on understanding how the ribosome functions at a molecular level and how changes in its activity lead to mRNA quality control...

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J. Marie Hardwick

Our laboratory studies the basic molecular mechanisms of programmed cell death, an evolutionarily conserved process to eliminate cells. Because these pathways normally contribute to the millions of cell deaths that occur per day per individual, defects in cell death...

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Miho Iijima

Mechanisms of gradient sensing and chemotaxis are conserved in mammalian leukocytes and Dictyostelium amoebae. Both cells use G protein linked signaling pathways. PH domains specific for PtdIns(3,4)P2 and PtdIns(3,4,5)P3 bind to the membrane at the leading edge of the...

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Takanari Inoue

Research Focus Our research focuses on “synthetic cell biology” to dissect and reconstitute intricate signaling networks. In particular, we investigate positive-feedback mechanisms underlying the initiation of neutrophil chemotaxis (known as a symmetry breaking process), as well as spatio-temporally dynamic...

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Alex Kolodkin

Our research is focused on understanding how neuronal connectivity is established during development.  Our work investigates the function of extrinsic guidance cues and their receptors on axonal guidance, dendritic morphology, and synapse formation and function.  For several years we...

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Xinzhong Dong

My laboratory has taken a multidisciplinary approach to understand the cellular and molecular mechanisms of different types of somatosensations including pain and itch, which are initiated and mediated by primary sensory neurons in dorsal root ganglia (DRG). We identified...

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