Shanthini Sockanathan

The nervous system consists of a great variety of neurons and glia that together form the components and circuits necessary for nervous system function. Neuronal and glial diversity are generated through a series of highly orchestrated events that control...

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Shigeki Watanabe

My lab studies the cellular and molecular basis of synaptic transmission and plasticity. Neuronal signaling events at synapses determine circuit responses and result in specific behavioral outputs. This signaling is dynamic – modulated by synapse activity history and perceived...

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Katherine Wilson

We study the structure and function of the cell nucleus, ‘mothership’ of the human genome. We seek to understand how nuclear envelope (NE) membrane proteins interact with nuclear intermediate filament (‘lamina’) networks and other partners to collectively establish, protect...

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Tamara O’Connor

The outcome of most parasitic relationships is decided by an elaborate series of events involving hundreds of proteins. Understanding this interaction requires the analysis of the molecular mechanisms operating in both organisms and the causal relationships acting at the...

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Jennifer Pluznick

Our lab is interested in the role that chemosensation plays in regulating physiological processes, particularly in the kidney and the cardiovascular system. We have found that sensory receptors (olfactory receptors, taste receptors, and other G-protein coupled receptors) are expressed...

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Joel L. Pomerantz

My laboratory is interested in the molecular mechanisms by which cells interpret signals from their environment that instruct them to proliferate, differentiate, or die by apoptosis. This process is of fundamental importance in the development and function of the...

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Zhaozhu Qiu

Molecular Biology and Physiology of Ion Transport Chloride is the most abundant free negatively charged ion in the body. Chloride channels are cell-membrane embedded proteins, allowing the movement of chloride in and out of the cells. Defects in chloride...

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Anastasia Kralli

Organisms go through cycles of metabolic activity, driven by internal cues (circadian, circannual clocks) and physiologic/behavioral inputs (e.g. feeding/fasting, physical activity/rest). In addition, organisms face environmental challenges (physical, chemical or psychological stressors) that require continual adaptation of the pathways...

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Deborah Andrew

We study how epithelial tubular organs – which are essential to life in all multicellular organisms – form and specialize. Using the simple unbranched tubes of the Drosophila salivary gland and the beautifully branched tubular network of the Drosophila...

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Rajini Rao

The Rao laboratory studies the role of novel ion transporters in human health and disease. One project focuses on the calcium signaling in breast cancer. We showed that an isoform of the secretory pathway Ca2+-ATPase, SPCA2, interacts with ion...

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