Shanthini Sockanathan

The nervous system consists of a great variety of neurons and glia that together form the components and circuits necessary for nervous system function. Neuronal and glial diversity are generated through a series of highly orchestrated events that control...

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Shigeki Watanabe

My lab studies the cellular and molecular basis of synaptic transmission and plasticity. Neuronal signaling events at synapses determine circuit responses and result in specific behavioral outputs. This signaling is dynamic – modulated by synapse activity history and perceived...

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Katherine Wilson

Within each human cell is a NUCLEUS, ‘mothership’ of the human genome and still the least-understood cellular structure. Chromosomes are enclosed by the nuclear envelope (NE) and communicate with the cytoplasm through Nuclear Pore Complexes (NPCs). The inner and...

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Seth Margolis

Synapses are specialized cell-cell junctions which connect individual neurons together and are the sites of transmission of information between neurons.While the molecular mechanisms which promote synapse formation have been a subject of intense investigation, little is known about the...

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Mollie K. Meffert

The goal of the Meffert lab is to gain a mechanistic understanding of how selective gene programs are recruited and maintained to modify the nervous system during development, experience-dependent plasticity, and in injury or disease.  Rather than focusing on...

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Tamara O’Connor

The outcome of most parasitic relationships is decided by an elaborate series of events involving hundreds of proteins. Understanding this interaction requires the analysis of the molecular mechanisms operating in both organisms and the causal relationships acting at the...

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Jennifer Pluznick

Our lab is interested in the role that chemosensation plays in regulating physiological processes, particularly in the kidney and the cardiovascular system. We have found that sensory receptors (olfactory receptors, taste receptors, and other G-protein coupled receptors) are expressed...

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Joel L. Pomerantz

My laboratory is interested in the molecular mechanisms by which cells interpret signals from their environment that instruct them to proliferate, differentiate, or die by apoptosis. This process is of fundamental importance in the development and function of the...

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Zhaozhu Qiu

Chloride is the most abundant free negatively charged ion in the body. Chloride channels are cell-membrane embedded proteins, allowing the movement of chloride in and out of the cells. Defects in chloride fluxes are responsible for many human disorders....

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Daniel Raben

A major effort in our laboratory focuses on understanding the biochemistry and chemistry underlying the molecular aspects involved in regulating lipid metabolizing signaling enzymes and the physiological roles of this regulation. Control of lipid metabolizing enzymes involves the modulation...

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