Douglas Robinson

Multi-cellular living organisms grow from single cells into multicellular, complex systems composed of highly diverse cell-types organized into tissues, which in turn form organs and organ systems. To organize and maintain this complex architecture, the organism must undergo constant...

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Ronald Schnaar

Our work bridges from biochemical to preclinical translational studies to harness the power of glycobiology for therapeutic benefits. All cells are endowed with a diverse coat of glycans, their “glycocalyx,” which represents the face of the cell to the...

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Hiromi Sesaki

Our laboratory is interested in the molecular mechanisms and physiological roles of mitochondrial fusion. Mitochondria are highly dynamic and control their morphology by a balance of fusion and fission. The regulation of membrane fusion and fission generates a striking...

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Geraldine Seydoux

Our lab studies gene regulation in germ cells, with a focus on “RNA granules” which are phase-separated compartments rich in RNA and proteins. We have identified a family of intrinsically-disordered proteins that form gel-like assemblies that sequester RNA (RNA...

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Theresa A. Shapiro

The central theme of our research is chemotherapy of malaria and African sleeping sickness. On a molecular basis, we are interested in understanding the mechanism of action for existing agents, and in identifying vulnerable targets for much-needed new chemotherapy....

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Robert Siliciano

For the 34 million people infected with HIV-1, the best current hope for avoiding the fatal consequences of the infection lies in treatment with antiretroviral therapy (ART), which consists of combinations of three drugs that inhibit specific steps in...

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Solomon H. Snyder

Neurotransmitters, Second Messengers and Drug Action in the Nervous System Our lab studies diverse signaling systems including those of neurotransmitters and second messengers as well as the actions of drugs upon these processes.  We have been interested in atypical...

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Shanthini Sockanathan

The nervous system consists of a great variety of neurons and glia that together form the components and circuits necessary for nervous system function. Neuronal and glial diversity are generated through a series of highly orchestrated events that control...

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Jungsan (Jay) Sohn

Research Interests: We are interested in understanding mechanisms that allow biological stress-sensors to detect danger signals and initiate highly coordinated coping-responses by assembling into higher order molecular assemblies. Innate immunity is the first line of defense against invading pathogens...

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Shigeki Watanabe

My lab studies the cellular and molecular basis of synaptic transmission and plasticity. Neuronal signaling events at synapses determine circuit responses and result in specific behavioral outputs. This signaling is dynamic – modulated by synapse activity history and perceived...

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