Angelika Doetzlhofer

Auditory hair cells, located in the inner ear cochlea are critical for our ability to detect sound. In mammals, neural innervated hair cells come in two flavors: inner hair cells, which are our primary mechanoreceptor and relay sound information...

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Seth Blackshaw

The vertebrate central nervous system (CNS) is an amazingly complex structure composed of distinct subtypes of neurons and glia. Our lab aims to identify the molecular mechanisms that control the generation of the major cell types of the vertebrate...

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Image of Sergi Regot

Sergi Regot

A fundamental property of living cells is their extraordinary ability to sense and respond to a changing environment. In higher eukaryotes, malfunctioning of signaling networks has many devastating consequences such as cancer, diabetes or autoimmunity. Such consequences arise from...

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Hiromi Sesaki

Our laboratory is interested in the molecular mechanisms and physiological roles of mitochondrial fusion. Mitochondria are highly dynamic and control their morphology by a balance of fusion and fission. The regulation of membrane fusion and fission generates a striking...

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Geraldine Seydoux

Our lab studies the earliest stages of embryogenesis to understand how single-celled eggs develop into complex multicellular embryos. We study how RNAs and proteins become localized to pattern the developmental potential of newly fertilized eggs. We have identified a...

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Shanthini Sockanathan

The nervous system consists of a great variety of neurons and glia that together form the components and circuits necessary for nervous system function. Neuronal and glial diversity are generated through a series of highly orchestrated events that control...

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Sean Taverna

Eukaryotic cells package their genomes in the form of chromatin, which is comprised of histone proteins and DNA. Modification of chromatin by chemical marks such as methylation and acetylation affects how cellular machineries interpret the genome. The Taverna laboratory...

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Patrick Cahan

My lab is an interdisciplinary group that devises and experimentally tests computational tools to explore cell type identity and its molecular underpinnings. A unifying component of our research is the gene regulatory network (GRN). GRNs are programs encoded in...

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Deborah Andrew

We study how epithelial tubular organs – which are essential to life in all multicellular organisms – form and specialize. Using the simple unbranched tubes of the Drosophila salivary gland and the beautifully branched tubular network of the Drosophila...

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