Faculty

Richard Ambinder

James B. Murphy Professor

Virology and human cancer; antiviral therapy; antitumor therapy; lymphoma pathogenesis and treatment

Faculty Pharmacology and Molecular Sciences Immunology Virology

Deborah Andrew

Professor

Building body parts – discovering the mechanisms by which organs achieve their unique architectures and physiological specializations during embryonic development

Faculty Cell Biology Cell Adhesion Cell Differentiation Cell Migration Developmental Biology Genetics Genomics/Proteomics Membranes Signal Transduction Transcription/RNA Processing Translation

Netzahualcóyotl Arroyo Currás

Assistant Professor

Pharmacokinetics, Biosensors, In-vivo sensing

Faculty Metabolism Signal Transduction Single Molecule Biophysics

Scott Bailey

Associate Professor

Structural and molecular mechanisms in nucleic-acid biology

Faculty Chemical Biology DNA Replication Enzymology Noncoding RNA Structural Biology Transcription/RNA Processing

James C. Barrow

Professor

Drug discovery for disorders of neurodevelopment

Faculty Pharmacology and Molecular Sciences Channels/Transporters Chemical Biology Drug Design Neurobiology

James M. Berger

Professor

Structural and molecular mechanisms of nucleic-acid machines and assemblies; control of DNA replication and chromosome superstructure

Faculty Biophysics and Biophysical Chemistry Enzymology Genome Structure/Chromatin Structural Biology Cancer Biology Chemical Biology DNA Replication Drug Design

Seth Blackshaw

Professor

Building and rebuilding the Retina and hypothalamus

Faculty Neuroscience Developmental Biology Epigenetics Genome Structure/Chromatin Genomics/Proteomics Metabolism Neurobiology Noncoding RNA

Solange Brown

Associate Professor

Functional organization of the neocortex

Faculty Neuroscience Genomics/Proteomics Neurobiology Sensory Biology

Patrick Cahan

Associate Professor

Hybrid experimental/ computational lab studying gene regulatory networks in development, stem cell engineering, and cancer

Faculty Cancer Biology Cell Differentiation Computational Biology Developmental Biology Genomics/Proteomics Stem Cell Biology

Danfeng Cai

Assistant Professor

Biomolecular condensates in homeostasis and cancer

Faculty Nuclear Structure Single Molecule Biophysics Transcription/RNA Processing Cancer Biology Genome Structure/Chromatin

Gregory V. Carr

Associate Professor

Preclinical models of neurological and psychiatric disorders

Faculty Genetics Neurobiology Developmental Biology Drug Design

Michael Caterina

Solomon H. Snyder Professor of Neurosurgery, Professor of Biological Chemistry & Neuroscience

Molecular and Cellular Mechanisms of Pain Sensation

Faculty Biological Chemistry Channels/Transporters Neurobiology Noncoding RNA Sensory Biology Signal Transduction

Steven Claypool

Associate Professor

Mitochondrial Phospholipid Metabolism in Health and Disease

Faculty Physiology Channels/Transporters Membranes Metabolism

Janice Clements

Professor and Vice Dean for Faculty

Molecular Pathogenesis and Latency of SIV & HIV

Faculty Molecular Biology and Genetics Immunology Virology

Luisa Cochella

Assistant Professor

Transcriptional and Post-transcriptional Mechanisms for Cell Diversification

Faculty Molecular Biology and Genetics Noncoding RNA Transcription/RNA Processing Cell Differentiation Developmental Biology Epigenetics Genetics

Robert N. Cole

Assistant ProfessorDirector of Mass Spectrometry and Proteomics Facility, Director of Mass Spectrometry Core for Johns Hopkins Kimmel Cancer Center

Functional interactions of proteins in human health and disease.

Faculty Biological Chemistry Cancer Biology Cell Adhesion

Jeff Coller

Bloomberg Distinguished Professor of RNA Biology and Therapeutics

mRNA translation, mRNA stability, RNA modifications

Faculty Molecular Biology and Genetics Translation Computational Biology Genetics Genomics/Proteomics Noncoding RNA

Brendan Cormack

Professor

Fungal pathogenesis: the host-pathogen interaction for the yeast pathogen Candida glabrata

Faculty Molecular Biology and Genetics Genetics Genomics/Proteomics Microbiology Microbial Pathogenesis Transcription/RNA Processing

Peter Devreotes

Professor

Genetic analysis of chemotaxis eukaryotic cells

Faculty Cell Biology Cell Adhesion Cell Migration Computational Biology Developmental Biology Genetics

Angelika Doetzlhofer

Associate Professor

Cell specification and differentiation in the mammalian auditory system

Faculty Neuroscience Developmental Biology Neurobiology Noncoding RNA Sensory Biology

Xinzhong Dong

Professor

Molecular and Cellular Studies of Somatosensation, Inflammation, and related diseases

Faculty Neuroscience Translation Immunology Neurobiology Sensory Biology Signal Transduction

Mikala Egeblad

Professor

Cancer Biology, metastasis, and innate immunity

Faculty Cell Biology Cancer Biology Cell Differentiation Cell Migration Immunology Signal Transduction

Peter Espenshade

Professor, Associate Dean for Graduate Biomedical Education

Mechanisms of Nutrient Sensing

Faculty Cell Biology Cancer Biology Genetics Genomics/Proteomics Membranes Membrane Traffic Metabolism Signal Transduction Transcription/RNA Processing Translation

Andrew Ewald

Professor

Cellular mechanisms and molecular regulation of epithelial morphogenesis during development and breast cancer

Faculty Cell Biology Cancer Biology Cell Adhesion Cell Division Cell Migration Developmental Biology Genetics

Bloomberg Distinguished Professor of Epigenetics Professor of Medicine, Biomedical Engineering, Oncology, Molecular Biology & Genetics, Psychiatry & Behavioral Sciences, Biostatistics, and Mental Health

Epigenetics in development and disease

Faculty Molecular Biology and Genetics Noncoding RNA Chemical Biology Nuclear Structure Computational Biology Stem Cell Biology Developmental Biology Structural Biology Drug Design Transcription/RNA Processing Epigenetics Genetics Genome Structure/Chromatin Genomics/Proteomics Cancer Biology Metabolism Cell Differentiation Neurobiology Cell Migration

Caren L. Freel Meyers

Professor

Medicinal chemistry, chemical biology, drug delivery, bacterial isoprenoid and vitamin and biosynthesis, design of anti-infective strategies

Faculty Pharmacology and Molecular Sciences Enzymology Chemical Biology Drug Design

Dominique Frueh

Associate Professor

NMR studies of active enzymatic systems: dynamic molecular communication in Nonribosomal Peptide Synthetases

Faculty Biophysics and Biophysical Chemistry Structural Biology Chemical Biology Computational Biology Drug Design Enzymology Microbial Pathogenesis

Dax Fu

Associate Professor

Zinc physiology with a focus on structure, function and regulation of zinc transporters

Faculty Physiology Channels/Transporters Structural Biology

Ryuya Fukunaga

Associate Professor

Mechanism and biology of small silencing RNAs

Faculty Biological Chemistry Enzymology Genetics Noncoding RNA Transcription/RNA Processing Translation

Luis Garza

Professor

Stem Cells and Regeneration

Faculty Cell Differentiation Developmental Biology Noncoding RNA Stem Cell Biology

Loyal Goff

Assistant Professor

Long non-coding RNAs in neural cell fate decisions

Faculty Neuroscience Cell Differentiation Channels/Transporters Computational Biology Developmental Biology Genome Structure/Chromatin Genomics/Proteomics Neurobiology Noncoding RNA Transcription/RNA Processing

Erin Goley

Associate ProfessorBCMB Admissions Director

Bacterial cell biology: growth, division, and shape regulation

Faculty Biological Chemistry Cell Division Cytoskeleton Microbiology

Stephen Gould

Professor

Exosome biogenesis and retrovirus budding

Faculty Biological Chemistry Developmental Biology Genetics Virology

Rachel Green

Bloomberg Distinguished ProfessorDirector, BCMB Graduate Program

Mechanisms of Ribosome Translation and Translational Control

Faculty Molecular Biology and Genetics Translation Enzymology Noncoding RNA Transcription/RNA Processing

J. Marie Hardwick

Professor

Molecular mechanisms of programmed cell death and its role in viral pathogenesis

Faculty Pharmacology and Molecular Sciences Cancer Biology Cell Death Membranes Metabolism Neurobiology Virology

Taeyoung Hwang

Assistant Professor

Regulatory RNA in brain development and disorders, RNA genomics

Faculty Cancer Biology Computational Biology Epigenetics Genome Structure/Chromatin Genomics/Proteomics Neurobiology Noncoding RNA Stem Cell Biology Transcription/RNA Processing

Miho Iijima

Professor

Lipid Signaling in Chemotaxis

Faculty Cell Biology Cell Migration Cytoskeleton Genetics Membranes Signal Transduction Cancer Biology Cell Division

Takanari Inoue

Professor, BCMB Program Director

Synthetic cell biology: total synthesis of cellular functions such as neutrophil chemotaxis and ciliary mechano-sensation

Faculty Cell Biology Signal Transduction Cell Migration Chemical Biology Cytoskeleton Membranes

Reza Kalhor

Assistant Professor

Genomics, Synthetic Biology, Developmental Biology

Faculty Stem Cell Biology Cell Differentiation Cell Division Computational Biology Developmental Biology Epigenetics Genetics Genome Structure/Chromatin Genomics/Proteomics Neurobiology Nuclear Structure

Tomomi Karigo

Assistant Professor

Neural circuit mechanisms underlying the development of social behaviors

Faculty Developmental Biology Neurobiology

Jennifer Kavran

Assistant Professor

Mechanistic studies of eukaryotic signaling pathways

Faculty Chemical Biology Developmental Biology Enzymology Signal Transduction Structural Biology Cancer Biology

Kebschull, Justus

Assistant Professor

Understanding the brain using evolution, viruses, and barcode sequencing.

Faculty Neuroscience Developmental Biology Genomics/Proteomics Neurobiology Transcription/RNA Processing Virology Computational Biology

Alex Kolodkin

Professor

Molecular Mechanisms of Neuronal Growth Cone Guidance

Faculty Neuroscience Cell Adhesion Cytoskeleton Developmental Biology Genetics Neurobiology Signal Transduction

Anastasia Kralli

Professor

Regulatory pathways that control adaptive metabolic responses in adipose and skeletal muscle tissues

Faculty Metabolism Signal Transduction Transcription/RNA Processing

Albert Lau

Associate Professor

Molecular mechanics of allostery and binding

Faculty Biophysics and Biophysical Chemistry Drug Design Neurobiology Signal Transduction Structural Biology Channels/Transporters Computational Biology

Anthony K. L. Leung

Professor

Laboratory of PARP biology in RNA metabolism

Faculty Chemical Biology Genomics/Proteomics Noncoding RNA Transcription/RNA Processing Translation Virology

Chang Liu

Assistant Professor

Mechanisms of viral and host gene regulation

Faculty Immunology Microbial Pathogenesis Structural Biology Transcription/RNA Processing Virology

Jian Liu

Associate Professor

Theoretical modeling, Mechanobiology, Cell Migration, Membrane trafficking, Cell Division

Faculty Cell Division Cell Migration Membrane Traffic

Jun Liu

Professor

Chemical biology and molecular biology; use of small molecules to probe important cellular processes and pathways; translational medicine

Faculty Pharmacology and Molecular Sciences Structural Biology Transcription/RNA Processing Cancer Biology Chemical Biology Drug Design Enzymology Immunology Signal Transduction

Svetlana Lutsenko

Professor

Human copper homeostasis: mechanism of copper transport, regulatory networks, the role in lipid metabolism, disorders of copper misbalance

Faculty Physiology Cell Differentiation Channels/Transporters Membranes Membrane Traffic Metabolism

Jonathan Lynch

Assistant Professor

Microbiology, Host Microbe Symbiosis, Microbiome

Faculty Metabolism Microbiology Microbial Pathogenesis Neurobiology

Brady J. Maher

Associate Professor

Molecular and physiological basis of psychiatric disorders

Faculty Channels/Transporters Developmental Biology Neurobiology Stem Cell Biology

Seth Margolis

Associate Professor

Molecular Mechanisms of Synapse Formation in Development and Disease

Faculty Biological Chemistry Cytoskeleton Developmental Biology Neurobiology Signal Transduction

Keri Martinowich

Associate Professor

Regulation of experience-dependent gene expression in brain circuits that control behavior

Faculty Neurobiology Noncoding RNA Signal Transduction Transcription/RNA Processing Developmental Biology

Erika Matunis

Professor

Signals Regulating Stem Cell Self-renewal

Faculty Cell Biology Cell Differentiation Developmental Biology Epigenetics Genetics Stem Cell Biology

Mollie K. Meffert

Associate Professor

The Regulation of Neuronal Gene Expression in Health and Disease

Faculty Biological Chemistry Cancer Biology Genomics/Proteomics Neurobiology Noncoding RNA Signal Transduction Transcription/RNA Processing Translation

Susan Michaelis

Professor

The premature aging disease progeria and lamin A processing; ubiquitin-proteasome mediated protein quality control.

Faculty Cell Biology Channels/Transporters Enzymology Genetics Genome Structure/Chromatin Membranes

Joshua Modell

Assistant Professor

Molecular mechanisms of CRISPR-Cas Immunity

Faculty Immunology Microbiology Microbial Pathogenesis Noncoding RNA Signal Transduction Transcription/RNA Processing Virology Computational Biology DNA Replication Genetics Genomics/Proteomics

Ulrich Mueller

Bloomberg Distinguished ProfessorDirector, Developmental Neuroscience

Auditory Perception and Development of Neocortical Circuits

Faculty Cell Migration Channels/Transporters Cytoskeleton Developmental Biology Genetics Neurobiology Sensory Biology Signal Transduction Cell Adhesion Stem Cell Biology Cell Differentiation Cell Division

Jeremy Nathans

Professor

Molecular mechanisms of retinal development and disease; the role of Frizzled receptors in mammalian development

Faculty Molecular Biology and Genetics Neurobiology Sensory Biology Developmental Biology Genetics

Tamara O’Connor

Assistant Professor

Molecular dissection of host-pathogen interactions and the evolution of virulence strategies in natural reservoirs

Faculty Biological Chemistry Genetics Immunology Microbiology Microbial Pathogenesis Signal Transduction

Bindu Paul

Assistant Professor

Redox signaling in aging and neurodegeneration

Faculty Pharmacology and Molecular Sciences Cell Differentiation Immunology Channels/Transporters Membrane Traffic Chemical Biology Metabolism Cytoskeleton Microbiology Developmental Biology Neurobiology Drug Design Signal Transduction Enzymology Structural Biology Epigenetics Transcription/RNA Processing Genetics Virology Genome Structure/Chromatin Cell Death Genomics/Proteomics

Diane Peters

Assistant Professor

Development of novel small molecule therapeutics for inflammatory bowel disease; in vivo pharmacology.

Faculty

Piacentino, Michael

Assistant Professor

Epithelial-to-mesenchymal transition (EMT)

Faculty Developmental Biology Genomics/Proteomics Membranes Membrane Traffic Metabolism Signal Transduction Stem Cell Biology Cell Adhesion Cell Differentiation Cell Migration Cytoskeleton

Jennifer Pluznick

Associate Professor

Elucidating the role of sensory receptors, such as olfactory receptors, in regulating renal function

Faculty Physiology Signal Transduction Metabolism Sensory Biology

Joel L. Pomerantz

Associate Professor

Functional Specificity and Design of Signal Transduction Pathways

Faculty Biological Chemistry Translation Virology Cancer Biology Cell Death Cell Division Genetics Genome Structure/Chromatin Immunology Microbial Pathogenesis Signal Transduction Transcription/RNA Processing

Christopher J. Potter

Associate Professor

Insect Olfaction: Molecules, Neurons, and Behavior

Faculty Neuroscience Developmental Biology Genetics Neurobiology Sensory Biology

Bethany Powell Gray

Assistant Professor

Using nucleic acid chemistry and biology to create safer cancer drugs and tunable imaging agents for cancer detection

Faculty Pharmacology and Molecular Sciences

Zhaozhu Qiu

Associate Professor

Molecular Biology and Physiology of Ion Transport

Faculty Physiology Neurobiology Sensory Biology Signal Transduction Channels/Transporters Membranes

Rajini Rao

Professor

Ion transport in health and disease. Emerging roles for Ca²⁺ signaling and endosomal pH in cancer, autism and neurodegenerative disorders

Faculty Physiology Cancer Biology Channels/Transporters Membranes Microbial Pathogenesis Neurobiology Signal Transduction

Karen Reddy

Assistant Professor

Understanding how the nuclear periphery and other subcompartments contribute to general nuclear architecture and to specific gene regulation

Faculty Biological Chemistry Epigenetics Genome Structure/Chromatin Genomics/Proteomics Nuclear Structure Transcription/RNA Processing

Sergi Regot

Assistant Professor

Signaling Network Dynamics at Single Cell Level

Faculty Molecular Biology and Genetics Cell Differentiation Computational Biology Developmental Biology Immunology Signal Transduction Cancer Biology

Douglas Robinson

Professor

Cytokinesis and Cell Shape Control

Faculty Cell Biology Genetics Cancer Biology Cell Division Chemical Biology Computational Biology Cytoskeleton

Ronald Schnaar

Professor

Molecular basis of cell-cell interactions in the nervous and immune systems; glycobiology

Faculty Pharmacology and Molecular Sciences Cell Adhesion Glycobiology Immunology Membranes Neurobiology Signal Transduction

Hiromi Sesaki

Professor

Molecular Mechanisms and Physiological Roles of Mitochondrial Fusion and Division

Faculty Cell Biology Enzymology Genetics Genomics/Proteomics Immunology Signal Transduction Developmental Biology

Geraldine Seydoux

Professor

Developmental genetics: RNA and protein dynamics in embryos

Faculty Molecular Biology and Genetics Developmental Biology Genetics Transcription/RNA Processing Translation

Theresa A. Shapiro

Professor

Discovery, development and clinical trials of drugs for malaria and sleeping sickness; in vitro pharmacokinetics-pharmacodynamics; long-acting chemoprophylaxis

Faculty Pharmacology and Molecular Sciences Chemical Biology DNA Replication Drug Design Genome Structure/Chromatin Metabolism

Robert Siliciano

Professor

Host-virus interaction in HIV infection

Faculty Molecular Biology and Genetics Immunology Microbial Pathogenesis Virology

Solomon H. Snyder

Professor

Neurotransmitters, Second Messengers and Drug Action in the Nervous System

Faculty Neuroscience Signal Transduction

Shanthini Sockanathan

Professor

Mechanisms of differentiation and degeneration in the nervous system

Faculty Neuroscience Cell Death Developmental Biology Membranes Neurobiology Signal Transduction

Jungsan (Jay) Sohn

Associate Professor

Understanding how biological stress-sensors are assembled, detect danger signals, and initiate stress-response

Faculty Biophysics and Biophysical Chemistry Structural Biology Chemical Biology Enzymology Immunology

Genevieve Stein-O’Brien

Assistant Professor

Single cell gene molecular profiling. Study of human diseases as a source of variation in phenotypes and genotypes.

Faculty Neuroscience Stem Cell Biology Transcription/RNA Processing Cancer Biology Cell Differentiation Computational Biology Developmental Biology Epigenetics Genetics Neurobiology

Shuying Sun

Associate Professor

RNA metabolism dysfunction and RNA-targeting therapy in neurodegeneration

Faculty Noncoding RNA Nuclear Structure Transcription/RNA Processing Translation Cell Death Epigenetics Genome Structure/Chromatin Neurobiology

Winston Timp

Associate Professor

Sequencing Technology Development and Application to Genetics, Epigenetics and Transcriptomics

Faculty Genetics Genome Structure/Chromatin Genomics/Proteomics Single Molecule Biophysics Transcription/RNA Processing Cancer Biology Computational Biology Epigenetics

Edward Twomey

Assistant Professor

Structural and molecular mechanisms of neurotransmission and protein homeostasis.

Faculty Biophysics and Biophysical Chemistry Channels/Transporters Membranes Membrane Traffic Structural Biology

Jiou Wang

Professor

Protein and RNA Homeostasis in Neurodegeneration

Faculty Noncoding RNA Signal Transduction Transcription/RNA Processing Translation Chemical Biology Computational Biology Epigenetics Genetics Genome Structure/Chromatin Metabolism Neurobiology

Shigeki Watanabe

Associate Professor

Cellular and molecular characterizations of rapid changes during synaptic plasticity

Faculty Cell Biology Signal Transduction Structural Biology Cell Adhesion Cell Death Channels/Transporters Cytoskeleton Membranes Membrane Traffic Metabolism Neurobiology Sensory Biology

Katherine Wilson

Professor

Nuclear envelope, lamins and nucleoskeleton; Emery-Dreifuss muscular dystrophy

Faculty Cell Biology Cancer Biology Genetics Genome Structure/Chromatin Glycobiology Metabolism Nuclear Structure Signal Transduction Transcription/RNA Processing

Cynthia Wolberger

Professor

Structural and molecular mechanisms of ubiquitin signaling and chromatin modification; regulation of transcription

Faculty Biophysics and Biophysical Chemistry Enzymology Epigenetics Genome Structure/Chromatin Structural Biology Transcription/RNA Processing

Michael Wolfgang

Professor

Cellular and organismal metabolism

Faculty Biological Chemistry Metabolism Neurobiology Chemical Biology Enzymology Genetics

G. William Wong

Professor

Systems Physiology of Peptide Hormones

Faculty Physiology Metabolism Signal Transduction

Paul Worley

Professor

Molecular mechanism of neuronal plasticity

Faculty Neuroscience Signal Transduction

Bin Wu

Assistant Professor

Single molecule imaging, RNA biology, neuroscience and gene expression

Faculty Biophysics and Biophysical Chemistry Cancer Biology Single Molecule Biophysics

Carl Wu

Bloomberg Distinguished Professor

Chromatin remodeling as a fundamental regulator of gene activity

Faculty Epigenetics Genome Structure/Chromatin Genomics/Proteomics Nuclear Structure Transcription/RNA Processing Cell Differentiation Enzymology

Mark Wu

Professor

Molecular and Circuit Mechanisms Underlying Motivated Behavior

Faculty Channels/Transporters Genetics Neurobiology Signal Transduction

Jie Xiao

Professor

Single-molecule and single-cell studies of cell division, chromosome conformation, transcription and gene regulation

Faculty Biophysics and Biophysical Chemistry DNA Replication Genome Structure/Chromatin Microbiology Single Molecule Biophysics Transcription/RNA Processing Cancer Biology Cell Division Cytoskeleton

King-Wai Yau

Professor

Cellular and Molecular Neuroscience

Faculty Neuroscience Channels/Transporters Membranes Neurobiology Sensory Biology Signal Transduction

Natasha Zachara

Associate Professor

O-GlcNAc, A Novel Regulator of the Cellular Stress Response and Cell Surival

Faculty Biological Chemistry Cancer Biology Cell Death Enzymology Genomics/Proteomics Glycobiology Metabolism Signal Transduction

Heng Zhu

Professor

Signal Transduction, protein network, host-pathogen interaction, protein chip approach to study proteomics

Faculty Pharmacology and Molecular Sciences Transcription/RNA Processing Genomics/Proteomics

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